40 results about "Cerebrospinal fluid flow" patented technology

The disclosure is directed to an implantable device for sensing CSF flow through an implantable ventricular shunt. The sensing device is implanted with the CSF shunt, and includes a flow sensor to sense flow rate or shunt blockage. The sensing device is either placed within or adjacent to the fluid path through the shunt. The sensing device transmits the sensed flow rate to an external monitoring device by wireless telemetry. The sensing device may be integrally formed as part of the shunt, or clamped onto a portion of the shunt, in which case the sensing device may be resusable. An external monitor receives the transmitted flow signal and presents information based on the flow signal. The sensing device may be inductively powered or include its own power supply.

An adjustable drainage system for regulating cerebrospinal fluid flow in a hydrocephalus patient where the drainage rate is adjusted in response to ventricular volume variations in the patient. The system includes an adjustable valve and a volume sensor that can be periodically energized with an external system controller device by the patient or attending physician to determine when, or if, a change in the ventricular volume has occurred. The system enables the user to adjust the valve's resistance in response to changes in the ventricular volume using the controller device so that a target ventricular volume can be achieved. Also provided is a method of continuously draining cerebrospinal fluid from the cranial cavity of the patient using the system of the present invention.

Cerebrospinal fluid shunts (implantable devices for diversion of excess fluid from the brain to other body cavities) used to treat hydrocephalus often malfunction. A common etiology of shunt malfunction is obstruction of the distal catheter tip by accumulating particulate matter such as fat or proteinaceous debris. The proposed implantable device maintains the patency of the cerebrospinal fluid shunt with mechanical energy which serves to “scrub” the catheter lumen of particulate debris. The proposed device accomplishes this by housing a source of mechanical energy which is coupled to the external aspect of the catheter, itself traversing through a bore in the device. The energy source secondarily induces a waveform in the cerebrospinal fluid flowing through the catheter. The fluid waveform exerts shearing forces on the catheter wall and serves to disrupt the formation and accumulation of debris that potentially could occlude the shunt catheter, thereby maintaining patency of the shunt.

A system for measuring quantitative CSF flow in shunt tubing implanted under the skin. The system includes an array of thermosensors clustered in three sections, cooling device, placed on the skin surface and an associated data acquisition and analysis device. Two sensor sections are placed over the shunt on the skin and measure real time temperature responses related to CSF movement. One array placed adjacent the cooling device collects data on thermal properties of skin including skin thermal condictivity, specific heat, diffusivity, perfusion, and thermal inertia. The method involves assessing thermal properties of skin and measuring CSF flow in shunt tubing. The method is useful for shunt patency assessment, CSF valve adjustment procedures and CSF flow measurements related to CSF over drainage. Alternatively, only one section of sensors need be used when determining relative CSF flow, without the need to determine thermal skin properties and by applying the cooling device continuously.

An implantable cerebral spinal fluid flow device and method. A body has an inlet for the cerebral spinal fluid, an outlet for the cerebral spinal fluid and a first interior cavity fluidly coupled with the inlet and the outlet. A first rotational element is mounted in the first interior cavity in a pathway between the inlet and the outlet. The first rotational element provides resistance to flow of the cerebral spinal fluid from the inlet to the outlet. In the method, the cerebral spinal fluid flow device is implanted. Resistance to rotation of the first rotational element to flow of the cerebral spinal fluid from the inlet to the outlet is provided.

The invention discloses a spinal puncture teaching model, belonging to the field of medical teaching. The spinal puncture teaching model comprises a spinal puncture model, a puncture needle, a cerebrospinal fluid flow guide device, an operation control circuit and a flexible drainage pipe, wherein the spinal puncture model consists of a lumbar vertebrae bone, a sacral vertebrae bone and a round pipe; a pressure sensor is arranged in the round pipe; a needle handle is provided with a side through pipe and a straight through pipe; the cerebrospinal fluid flow guide device consists of a liquid storage tank, a liquid feeding port, a liquid discharging port, cerebrospinal-fluid drainage liquid, a micropump, a micropump power supply circuit and a hydrops depth control floater; the operation control circuit consists of a power supply, a position indicating circuit and a hydrops depth control floater; and the position indicating circuit consists of a pressure sensor, an in-place indicating lamp and a relay. The spinal puncture teaching model disclosed by the invention has the beneficial effects that the effects of convenience, durability and intuition can be achieved, the notification of the operation practice working and the finishing condition information of spinal puncture can be directly realized, the repeated use can be achieved, and the purpose that the spinal puncture teaching model can bear the practice of repeated operation and training is realized.

The invention discloses a flow compensation method for a nuclear magnetic resonance imaging system. The flow compensation method is characterized by comprising the following steps that: (1) gradient combined pulses which satisfy flow compensation are applied in a frequency encoding direction between a 90-degree radio frequency pulse time series and a 180-degree radio frequency pulse time series of a fast spin echo (FSE) sequence; (2) a scattering gradient is applied before a signal acquisition gradient and before 180-degree radio frequency pulses, and a compensation gradient is applied after the acquisition gradient, and the signal acquisition gradient, the scattering gradient and the compensation gradient jointly form a first-order gradient velocity compensation gradient; (3) phase encoding gradient amplitude is set to be zero, and the time series of the sequence is set, and the amplitudes of the gradients are adjusted, and the amplitude of echo signal peaks of an echo chain is made to reach a maximum value, and the debugging of the sequence is completed; and (4) the sequence is outputted to a spectrometer, so that flow compensation can be realized. With the flow compensation method for the nuclear magnetic resonance imaging system of the invention adopted, situations such as cerebrospinal fluid flow and spinal fluid flow artifacts and image blurring can be significantly inhibited, and therefore, the problem of image artifact generation which is caused by physiological movement such as blood flow or periodic movement can be alleviated.

The present invention relates to a partial skull replacement consisting of polydimethylsiloxane (PDMS) and a method of monitoring biological tissues within a skull using the partial skull replacement. The method of monitoring using the partial skull replacement of the present invention has a minimal influence on intracranial pressure and cerebrospinal fluid flow as compared to a conventional cranial window technique using glass, and, by way of visualizing biological tissues within a skull with enhanced clarity, is expected to be usefully employed as a method of monitoring biological tissues within the skull.

The invention discloses a lumbar puncture needle, which comprises a needle, wherein the needle is provided with a tubular needle cavity, the tail of the needle is fixedly arranged on a handle, and the handle is provided with a cavity and a valve handle; the cavity consists of a handle cavity, a tubular handle cavity and a threaded through hole, the left end of the handle cavity communicates with the tubular handle cavity, the right end of the handle cavity communicates with the threaded through hole, the tubular needle cavity communicates with the tubular handle cavity, and the left end of the handle cavity is a conical tubular cavity surface; the valve handle comprises a threaded rod, the left end of the threaded rod is provided with an integrated valve handle cone, the right end of the threaded rod is provided with an integrated rotating handle, the threaded rod runs through the threaded through hole, the outer surface of the valve handle cone is matched with the conical tubular cavity surface, and the rotating handle is exposed on the right side of the handle; the bottom of the handle is provided with a fluid outlet seat, the top of the handle is provided with a pressure-measuring seat, the fluid outlet seat is provided with a valve, and the pressure-measuring seat is connected with a pressure-measuring device. The lumbar puncture needle can ensure that whether cerebrospinal fluid flows out or not can be directly viewed, can accurately control the flow of cerebrospinal fluid, and is easy and convenient to operate and safe to use.

An implantable shunt that includes one or more catheters configured so that the implantable shunt has a resistance to flow greater than about 3 mm Hg/mL/minute. An implantable shunt system that includes one or more catheters and a fluid control device that utilizes the properties of the catheters to improve the expected function of the shunt by providing a higher or lower resistance to the flow through the shunt and reduces the effect of pulsations of cerebrospinal fluid on the shunt system.

A magnetic resonance imaging apparatus according to an embodiment includes a collection unit and a generation unit. The collection unit collects data of an imaging area over a plurality of time phases within a certain respiratory cycle after applying a labeling pulse to a labeling area in which cerebrospinal fluid flows under a task of respiration. The generation unit generates images of a plurality of time phases depicting the cerebrospinal fluid by using the collected data.

The invention relates to a novel lumbar puncture needle capable of realizing semi-automatic needle insertion, belongs to the technical field of medical instruments, solves the problems of needle head displacement and too deep needle insertion caused by manual needle pushing in the existing lumbar puncture, and enables the needle insertion process to be more accurate and stable. The novel lumbar puncture needle structurally comprises a needle head, an electromagnetic three-way valve, an optical fiber sensor, a pressure sensor, a sensor shell, a stepping motor, a needle inserting track and a puncture needle shell, wherein the needle head is connected with the electromagnetic three-way valve. After cerebrospinal fluid flows in, three functional states are realized along with reversing of a valve core; the optical fiber sensor can be used for directly measuring the pressure of the cerebrospinal fluid; the stepping motor drives the needle head to slowly advance along a needle inserting track at a constant speed, so that needle inserting errors caused by manual needle pushing are avoided; and the pressure sensor measures the needle insertion resistance and provides a judgment basis for the needle insertion depth. Through semi-automatic reversing of the electromagnetic three-way valve, measurement of the pressure of the cerebrospinal fluid by the optical fiber sensor, constant-speed slow needle insertion driven by the stepping motor, and real-time reflection of needle insertion resistance by the pressure sensor, accurate and efficient lumbar puncture operation is realized.

The invention belongs to the technical field of medical equipment, and discloses a lumbar cistern drainage and intracranial pressure monitoring system. The system comprises a drainage tube (1), wherein a cerebrospinal fluid flowing channel (2) and a wire channel (3) are arranged on the drainage tube (1); a drainage hole (4) which communicates with the cerebrospinal fluid flowing channel (2) is formed in an insert-in end part of the drainage tube (1); a pressure sensor (5) is arranged on the insert-in end part of the drainage tube (1); the drainage tube (1) communicates with a connecting pipe (7) through an adapter (8); a flow controller (9) is arranged on the connecting pipe (7); and a backward-flow prevention structure is arranged at the tail end of the connecting pipe (7). According to the lumbar cistern drainage and intracranial pressure monitoring system disclosed by the invention, the change of intracranial pressure can be monitored, the drainage speed and the drainage volume of the cerebrospinal fluid can be controlled, and the backward-flow of the cerebrospinal fluid is avoided; and meanwhile, the risks of cerebral hernia caused by excessive amount of the drainage and over-high speed of the drainage during puncturing are avoided, and observation of the smoothness of the drainage of the cerebrospinal fluid is facilitated.

A method of determining a local cerebrospinal fluid flow rate. The method including the steps of positioning a distal end of the catheter in a flow of cerebrospinal fluid of the patient, the catheter including an infusion port and at least one temperature sensor positioned at a fixed distance from the infusion port, infusing a bolus of a temperature controlled fluid through the infusion port into the flow of cerebrospinal fluid, and monitoring a temperature sensed by the at least one temperature sensor, wherein a change in the temperature sensed by the at least one temperature sensor over time is representative of a local cerebrospinal fluid flow rate in proximity to the infusion port.

A process for reducing cerebrospinal fluid flow obstruction includes the administration of a therapeutic dose of a clot-reducing agent to a subject having preconditions or obstructive hydrocephalus symptoms. The dose is maintained within the subject for a period of time sufficient to reduce cerebrospinal fluid flow obstruction. The clot-reducing agent includes a plasminogen activator, a defibrinogenic agent, an anticoagulant, a platelet inhibitor and a combination thereof. A commercial kit is provided, containing a clot-reducing agent, an administering apparatus, together with instructions for use of the kit.

The invention discloses a cerebrospinal fluid drainage device and method. The cerebrospinal fluid drainage device comprises a drainage tubeline, a flow velocity sensor, a flow regulator and a drainagecontrol system, wherein the drainage control system comprises a man-machine interaction module and a drainage control module; the man-machine interaction module is used for inputting an expected flowvelocity/flow velocity range and an expected drainage amount, recording and displaying patient personal information, treatment information, a historical cerebrospinal fluid flow velocity and a current cerebrospinal fluid flow velocity, and judging a drainage state according to the current cerebrospinal fluid drainage amount and a real-time fluid flow velocity; and the drainage control module controls the flow regulator according to the current drainage state so as to enable the real-time fluid flow velocity to be equal to the expected flow velocity or fall into the expected flow velocity range or controls the current drainage to be paused/ended. The cerebrospinal fluid drainage device is simple in structure, automatic pressure and velocity regulation of automatic cerebrospinal fluid drainage can be achieved by directly improving a traditional cerebrospinal fluid drainage device, the pressure and velocity control precision is high, the product is reliable, and the use is convenient.

The invention discloses a cerebrospinal fluid stop valve. The erebrospinal fluid stop valve comprises a polysulfone plastic connector. The polysulfone plastic connector is axially provided with a first through hole. A groove communicated with the first through hole is formed in the polysulfone plastic connector. A silica gel membrane covers the orifice of the first through hole and is provided with a second through hole. The silica gel membrane is provided with a polysulfone plastic pressing cap matched with the polysulfone plastic connector. The polysulfone plastic pressing cap is provided with a third through hole. The first through hole, the second through hole and the third through hole are communicated with one another. The inner diameters of the first through hole and the third through hole are larger than the outer diameter of a catheter. The inner diameter of the second through hole is smaller than the outer diameter of the catheter. The cerebrospinal fluid stop valve has the advantages that the stop valve can effectively prevent cerebrospinal fluid from flowing out of a human body through the gap between a needle seat and the catheter during surgery, the surgery can be performed smoothly, the health of a patient is guaranteed, and the embarrassment of helplessness of doctors when the cerebrospinal fluid flows out of the human body during the surgery can be prevented effectively.

A medical device configured to improve dispersion of a medicament within cerebrospinal fluid of a patient is disclosed. The medical device includes an implantable catheter having: a distal tip configured to be positioned within a cerebrospinal fluid flow; a proximal tip; a body defining a lumen extending longitudinally along the implantable catheter, the lumen configured to enable a medicament to flow from the proximal tip to an infusion port positioned proximate the distal tip; and a piezoelectric element positioned proximate the infusion port, the piezoelectric element configured to selectively oscillate during administration of a medicament to improve dispersion of the medicament within the cerebrospinal fluid.

The invention relates to a sleeve type lumbar puncture needle and a use method thereof. The technical scheme of the invention is that the sleeve type lumbar puncture needle comprises a cylindrical needle head with an inner cavity, a handle with a communicating pipe cavity, and a trocar, wherein the needle head is provided with a first liquid outlet hole and a second liquid outlet hole; the trocar has a cylindrical structure matched with the inner cavity of the needle head and a through hole cavity; and the trocar is provided with a first liquid inlet hole, a second liquid inlet hole and a third liquid inlet hole. The sleeve type lumbar puncture needle provided by the invention has the technical effects that: a transparent observation window or a transparent handle is arranged to observe whether cerebrospinal fluid flows out or not intuitively and visually, the flow is controlled precisely when liquid is taken, the operation is convenient, and the setting and matching of the mutual positions between the first liquid outlet hole and the second liquid outlet hole, and the first liquid inlet hole, the second liquid inlet hole and the third liquid inlet hole enable the liquid outgoing manner and the liquid outgoing volume can be flexibly adjusted according to requirements of on-scene patients or operators. The sleeve type lumbar puncture needle is convenient to use, is safe and reliable, and is long in service life, accurate in adjustment, and complete in function.