The invention relates to the technical field of machines, in particular to a fixing device for lumbar puncture. The fixing device comprises a base, a back plate is arranged at the rear end of the base, a shoulder fixing plate is arranged at the right end of the back plate, a hip fixing plate is arranged at the left end of the back plate, and a chest fixing plate is arranged right in front of the back plate. The fixing device for lumbar puncture can be fixed to a puncture bed, and through the back plate, the shoulder fixing plate, the hip fixing plate and the chest fixing plate, a patient can be clamped and fixed inside the fixing device; by adjusting the distance between the shoulder fixing plate and the hip fixing plate, the fixing device adapts to patients with different body shapes, itis unnecessary to fix the body position of the patient by multiple persons, the patient also does not need to consume own physical power to keep a posture, and therefore a lot of labor is saved; in addition, the patient cannot move randomly easily in the fixing device, the surface of the fixing device is soft, people feel comfortable when touching the fixing device, a doctor can conveniently, rapidly and accurately conduct puncture operation, the speed of puncture operation is effectively increased, the efficiency of puncture operation is effectively improved, puncture time is shortened, and the pressure of the patient is relieved.