196results about How to "Prevent and reduce damage" patented technology

An organ perfusion apparatus and method monitor, sustain and/or restore viability of organs and preserve organs for storage and/or transport. Other apparatus include an organ transporter, an organ cassette and an organ diagnostic device. The method includes perfusing the organ at hypothermic and/or normothermic temperatures, preferably after hypothermic organ flushing for organ transport and/or storage. The method can be practiced with prior or subsequent static or perfusion hypothermic exposure of the organ. During the period in which the organ is preserved and/or maintained, the organ may be additionally be perfused to obtain data regarding the fluid and/or organ. The data may then be used to ultimately provide information regarding the perfusion efficacy and allow for altering of the perfusion parameters.

An organ perfusion apparatus and method monitor, sustain and/or restore viability of organs and preserve organs for storage and/or transport. The method includes perfusing the organ at hypothermic and/or normothermic temperatures, preferably after hypothermic organ flushing for organ transport and/or storage. The method can be practiced with prior or subsequent static or perfusion hypothermic exposure of the organ. Organ viability is restored by restoring high energy nucleotide (e.g., ATP) levels by perfusing the organ with a medical fluid, such as an oxygenated cross-linked hemoglobin-based bicarbonate medical fluid, at normothermic temperatures. In perfusion, organ perfusion pressure is preferably controlled in response to a sensor disposed in an end of tubing placed in the organ, by a pneumatically pressurized medical fluid reservoir, providing perfusion pressure fine tuning, overpressurization prevention and emergency flow cut-off. In the hypothermic mode, the organ is perfused with a medical fluid, preferably a simple crystalloid solution containing antioxidants, intermittently or in slow continuous flow. The medical fluid may be fed into the organ from an intermediary tank having a low pressure head to avoid organ overpressurization. Preventing overpressurization prevents or reduces damage to vascular endothelial lining and to organ tissue in general. Viability of the organ may be automatically monitored, preferably by monitoring characteristics of the medical fluid perfusate. The perfusion process can be automatically controlled using a control program.

A medical device comprises a stent having a reduced state and an expanded state and which is comprised of a plurality of interconnected struts. At least one strut is at least partially coated with a substance. The at least one strut has at least one bumper. The at least one bumper is constructed and arranged to prevent the substance on the at least one strut from being contacted by an adjacent component of the medical device when the stent is in the reduced state.

A light-emitting diode (LED) tube lamp with overcurrent and/or overvoltage protection capabilities includes a lamp tube, a first rectifying circuit, a filtering circuit, an LED lighting module, and a protection circuit. The lamp tube has pins for receiving an external driving signal. The first rectifying circuit is for rectifying the external driving signal to produce a rectified signal. The filtering circuit is for filtering the rectified signal to produce a filtered signal. The LED lighting module includes an LED module, wherein the LED lighting module is configured to receive the filtered signal to produce a driving signal, and the LED module is for receiving the driving signal for emitting light. The protection circuit is configured to determine whether to enter a protection state, wherein upon entering the protection state, the protection circuit works to limit or restrain the level of the filtered signal.

This invention provides compositions of active highly phosphorylated lysosomal sulfatase enzymes, their pharmaceutical compositions, methods of producing and purifying such lysosomal sulfatase enzymes and compositions and their use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the lysosomal sulfatase enzyme.

The present applications describes, inter alia, a retinal light management system that allows for removal of dangerous wavelengths of light while controlling the intensity of the remaining light that is allowed to pass to a user's eyes. In one embodiment, the system involves a pair of glasses that include filters that can be modified in the presence of light to reduce total light intensity reaching a diabetic's eyes.

A drain hose clip for securing a drain hose to a household appliance, and a household appliance having the drain hose clip and drain hose. The drain hose clip includes a body configured to be coupled to the drain hose and to secure the drain hose to the household appliance, and an orientation control feature on the body that engages a corresponding orientation control feature on the drain hose to maintain a fixed position of the drain hose with respect to the body of the drain hose clip.

An organ perfusion apparatus and method monitor, sustain and/or restore viability of organs and preserve organs for storage and/or transport. Other apparatus include an organ transporter, an organ cassette and an organ diagnostic device. The method includes perfusing the organ at hypothermic and/or normothermic temperatures, preferably after hypothermic organ flushing for organ transport and/or storage. The method can be practiced with prior or subsequent static or perfusion hypothermic exposure of the organ. Organ viability is restored by restoring high energy nucleotide (e.g., ATP) levels by perfusing the organ with a medical fluid, such as an oxygenated cross-linked hemoglobin-based bicarbonate medical fluid, at normothermic temperatures. During the period in which the organ is preserved and/or maintained, various drug research and development may be performed on and/or with the organ. The organ may be perfused with a fluid containing a substance such as a test substance to obtain data regarding the organ, the substance and an interaction of the substance and the organ. The data may then be used to ultimately provide information regarding the drugs efficacy in support of regulatory filings for new drugs.

Automated rotary brush harvesters that reduce or prevent damage to fruit or other crops (“produce”) when they are removed from trees or bushes, and methods of using such harvesters are disclosed. The harvesters may include a brush having flexible radiating members (e.g., filaments or bristles) for removing crops from trees or bushes and a conveyor paired therewith for receiving the produce from the brush. The brush and conveyor may be angled to aid in collecting the produce and preventing damage to the produce. The conveyor may be configured to deliver the produce to one or more bins, which may be mounted on a bin elevator system.

An organic light emitting diode (OLED) display device and a method of fabricating the same are provided. When an organic layer having an emission layer (EML) is formed using a deposition mask, damage to a pixel defining layer due to inconsistencies or unevenness of the deposition mask is prevented or reduced using spherical spacers disposed on the pixel defining layer. A plurality of spherical spacers are applied on the pixel defining layer prior to forming an opening in the pixel defining layer exposing the first electrode. An organic layer having an emission layer (EML) is formed on the first electrode at the opening by using a deposition mask. The spherical spacers prevent or reduce damage to the pixel defining layer caused by inconsistencies or unevenness in the deposition mask by maintaining a spacing between the pixel defining layer and the deposition mask.

A covering layer for a transcatheter heart valve is in various embodiments configured to prevent or reduce damage to the native valve tissue around the site where the prosthetic valve is implanted. In some cases, prosthetic valves are manufactured with the covering layer attached. Other covering layers are stand-alone accessories that can be mounted onto pre-existing prosthetic valves by an end user. Covering layers that can be mounted by an end user are provided with various features that can facilitate easier attachment of the covering layer to the prosthetic valve, which further reduces the possibility of damage to the covering layer or to the valve. Another covering is provided with two layers in order to insulate and protect the native tissue surrounding the implant from damage due to friction or abrasion, and/or other movement driven wear.

An adsorption drying apparatus, in particular for drying a compressed gas, includes an adsorption chamber (11) having a plurality of adsorption conduits (101) containing an adsorption material (123), a first feeding line (106) and a first discharging line (109) disposed at a first end (111) of the adsorption chamber (11), and a second feeding line (108) and a second discharging line (107) disposed at a second end (112) of the adsorption chamber (11). The adsorption chamber (11) is rotatable with respect to the feeding and discharging lines (106, 107, 108, 109) so that the adsorption conduits may be fluidically connected in temporal alternation, wherein the gas is dried in a drying sector (102), and the adsorption material (123) is regenerated in the regeneration sector (103). The first feeding line (106) is configured such that the gas stream to be dried may be fed to the regeneration sector (103) as a full flow. The second discharging line (107) is in communication with the second feeding line (108) and thus forms a connecting line in which a condenser is provided, and a pressure increasing device (18) is provided within the connecting line so as to increase the pressure of the gas flowing from the second discharging line (107) to the second feeding line (108). A cooling stream may be branched off at the first (111) or second end (112) of the adsorption chamber (11), as need be, to cool the adsorption chamber (11) within the cooling sector (119). The regeneration sector (103) and the drying sector (102) are connected in cascade for a serial through-flow, such that the gas stream fed to the drying sector (102) essentially completely corresponds to the gas stream discharged from the regeneration sector (103), optionally including the gas stream discharged from the cooling sector.

A motorcycle includes a guard frame provided near an upper portion of a vehicle body of the motorcycle that is arranged to reduce or prevent damage to the components of the motorcycle in the event of an overturn of the motorcycle. The guard frame includes a pair of guard frame rails, each rail extending in a longitudinal direction of the vehicle body. A connecting portion connects the rear end portions of the rails. The front end portion of each rail is fixed to a body frame of the motorcycle. The connecting portion is supported by the body frame for pivotal movement about a pivot axis. The rails have a normal bow shape that projects outwardly. In some arrangements, an intermediate portion of each rail is formed of a material having lower rigidity than a material of the front and rear end portions of the rail.

A backlight assembly includes a light source, a light-guiding member, a mold frame and a printed circuit board (“PCB”). The light source generates light. The light-guiding member guides the light generated from the light source. The mold frame receives the light-guiding member. An opening is formed through a side of the mold frame. The PCB drives the light source, and includes an extension portion extending through the opening of the mold frame.