17 results about "Nerve bundle" patented technology

The utility model discloses a bipolar electrode probe, comprising: an electrode assembly comprising two parallel electrode wires, each electrode wire comprising a contact portion and a transmission portion which are respectively close to two ends of the electrode wire, the contact portion being designed to be in a shape capable of picking up a nerve bundle; and the lead wire comprises two parallel wire harnesses, one end of each wire harness is electrically connected with one transmission part, and the other end of each wire harness is used for being connected with post-stage equipment. The nerve tract is picked up through the contact part extending into the lower part of the skin, so that the nerve tract is connected with a post-stage device through a lead wire, and nerve tract damage caused when the nerve tract is contacted by means of implantation, adhesion or puncture and the like is avoided.

The invention relates to the technical field of medical apparatus and instruments, and discloses a nerve repair fixing cannula, a flexible connection sheet can be bent into a tubular shape, so that two ends of the flexible connection sheet respectively wrap the peripheries of two nerve broken ends, the inner side of the flexible connection sheet is provided with a growth space, a tubular structure for nerve bridging is established, nerve axons grow directionally, and the two nerve broken ends are kept aligned; the multiple microneedles are arranged at the two ends of the flexible connecting piece at intervals, the connecting tension of the nerve bundle layer and the flexible connecting piece is dispersed, and the pain feeling of a patient is relieved; a needle head of the microneedle is used for being inserted into an adventitia so as to fix the bent flexible connecting piece to the nerve broken end, a needle rod penetrates through the flexible connecting piece, and the needle rod and the outer tangent plane of the bent flexible connecting piece at the needle threading position are obliquely arranged at a first preset angle, so that the mechanical stability of the nerve repair fixing sleeve installed on the nerve broken end is improved; the nerve broken end can be quickly and conveniently fixed, meanwhile, the damage to nerve tracts is reduced, and the situation that the nerve function recovery is affected by scars is avoided.

The object of this invention is to provide a method of producing a nerve bundle including efficiently extending axons of neural cells. As a solution to accomplish this end, neural cells are cultivated in the presence of feeder cells including at least one type of cells selected from vascular component cells and perivascular cells.

A pain management system includes: a resorbable electrode mounted on a substrate configured to be implanted on the nerve bundle of a patient, the resorbable electrode being configured to emit electrical pulses to the nerve bundle; and an electrical signal transmitter operatively and wirelessly connected with the resorbable electrode, the electrical signal transmitter configured to transmit signals to the electrode to generate electrical pulses, the electrical signal transmitter configured to be mounted on the patient's skin near the resorbable electrode.

The invention relates to the technical field of medical images, in particular to a nerve anesthesia puncture auxiliary positioning method based on an ultrasonic image, which comprises the following steps: acquiring a real-time ultrasonic image of a target area; carrying out automatic identification and segmentation on a neural structure in the ultrasonic image; fusing the probe space pose data acquired by the electromagnetic positioning system with the three-dimensional coordinates of the puncture needle; projecting a neural structure position and a virtual needle insertion path guide line on augmented reality display equipment in real time; compared with the prior art which depends on manual visual inspection of an ultrasonic image to position a neural structure and has the defects of high subjectivity, high requirement on operator experience and low minor nerve tract recognition rate, the scheme adopts a deep learning model based on an improved U-Net + + architecture; millimeter-level accurate recognition and segmentation of a neural structure are achieved in combination with a multi-modal fusion enhancement technology, the definition and stability of neural development under complex anatomical conditions are remarkably improved, and a reliable anatomical basis is provided for puncture path planning.

This invention discloses a method and system for image enhancement processing of traumatic neuropathic pain, relating to the fields of data processing and artificial intelligence. Based on multi-scale Gaussian difference edge extraction and structural tensor enhancement, this invention achieves precise preservation of blurred lesion boundaries; independently extracts structural features and optimal scale edge features to solve the problem of unbalanced feature responses caused by different lesion sizes; based on dual-path orthogonal constraints combined with spatial weight modulation, it achieves complete decoupling of lesion features from normal tissue; and utilizes edge features to generate a spatial attention mask to guide the reconstruction process while maintaining the continuity of nerve bundles and avoiding noise amplification. This achieves precise preservation of lesion details, effective suppression of noise, and structural reconstruction of the continuity of nerve bundles, providing clearer and more reliable imaging evidence for clinical diagnosis.

An apparatus includes a processor configured for communication with an intravascular imaging catheter. The processor is configured to control the intravascular imaging catheter to obtain a plurality of intravascular images during movement of the catheter along a length of a renal artery, where the plurality of intravascular images depicts one or more nerve bundles for targeting during a renal denervation treatment. The processor performs co-registration between a plurality of nerve bundle data points representative of the nerve bundles and associated with a treatment location along the length of the renal artery for the renal denervation treatment; and a first X-ray image of the renal artery obtained with a contrast fluid inside the renal artery. The processor outputs, to a display, a screen display based on the co-registration and configured to guide a user regarding the renal denervation treatment.

The application discloses an esterase-responsive lipid prodrug capsaicin nanoassemblies as well as a preparation method and application thereof, the nanoassemblies are formed by self-assembly of lipid prodrug capsaicin in an aqueous medium, and the average particle size of the nanoassemblies is 50-300 nm. The nanoassemblies can efficiently penetrate a nerve bundle membrane barrier, locally form a drug depot in nerve tissue, and slowly release active capsaicin under the action of esterase, so that long-acting, safe and selective analgesia is realized, and key problems such as poor permeability of free capsaicin, severe burning pain caused by injection, and narrow treatment window are solved.

The invention discloses a method and a device for evaluating the degree of invasion of a nerve and blood vessel bundle by a tumor, and the method comprises the steps: obtaining two-parameter resonance imaging of a patient, and extracting at least two modal data in the two-parameter resonance imaging; performing data alignment on the at least two types of modal data; inputting the at least two aligned modal data into a trained segmentation model, and outputting mask data including tumor and vascular nerve tract areas; converting the mask data into point cloud data; and calculating the geometrical relationship between the tumor and the vascular nerve tract region in the point cloud data, and judging the invasion degree between the tumor and the vascular nerve tract region based on the geometrical relationship between the tumor and the vascular nerve tract region and a preset invasion judgment rule. According to the invention, high-precision automatic segmentation of the tumor and vascular nerve tract area of the prostate cancer can be realized.

A method or actions performed by a processor of a system includes displaying a representation of multiple tracts, fibers, nerve bundles, modulation targets, or symptoms, and a representation of electrodes of a cuff lead; in response to selection of at least one of the electrodes, displaying an indication of which tracts, fibers, or nen e bundles can be activated or which modulation targets or symptoms can be affected, using the at least one selected electrode; in response to selection of one of the tracts, fibers, nerve bundles, modulation targets, or symptoms, displaying an indication of at least one of the electrodes for activating the selected tract, fiber, or nerve bundle or for affecting the selected modulation target or symptom; and, optionally, programming a stimulator to stimulate the nerve using the at least one selected electrode or the at least one indicated electrode.

The utility model relates to the technical field of medical instruments, in particular to a suturing auxiliary device which comprises a main body and an auxiliary part matched with the main body, the main body comprises an inner cylinder capable of being arranged between suturing tissues and an outer cylinder used for fixing the inner cylinder, an outer cylinder clamping end is arranged on the inner wall of the outer cylinder, and the auxiliary part is matched with the main body. The outer wall of the inner cylinder is provided with an outer cylinder clamping end, the outer wall of the inner cylinder is provided with an inner cylinder limiting end connected with the outer cylinder clamping end in a matched mode, the outer cylinder is provided with a locking piece, the auxiliary piece comprises a matching piece, and the matching piece is matched with the locking piece so that the outer cylinder can be switched between the locking state and the opening state. Through the cooperation of the inner cylinder and the outer cylinder and the action of the locking piece and the matching piece, the stability and the alignment state of a nerve bundle group in the operation process can be ensured, and the efficiency and the success rate of nerve suturing are improved; according to the utility model, a complicated connecting piece chute and a complicated sliding fastener do not need to be designed, so that the requirement on the process fineness is reduced, and the operation convenience is improved.

A system and method for prostate cancer treatment under local anesthesia includes creating a superficial skin and subcutaneous block in a perineal area of a patient by administering a first anesthetizing agent; creating a deep nerve block under ultrasound guidance by administering a second anesthetizing agent, the second anesthetizing agent infiltrating cavernosal nerve bundle tissue and periprostatic space; and ablating prostate tissue. The office-based method, statistical models and computer generated treatment plans identify and ablate prostate tissue containing cancer through or via the perineum while preserving prostate function, and critical anatomical structures. Multiple technologies are integrated and processed to deliver a safe treatment procedure, under local anesthesia by integrating the information of magnetic resonance imaging and planning the ablative treatment using algorithms that ensure maximal precision in both killing cancerous tissue and preserving healthy tissue along with its corresponding function.

The invention discloses a prostate cancer radical operation nerve real-time positioning method and system based on near infrared fluorescence imaging. Comprising the following steps: intravenously injecting an indocyanine green fluorescence contrast agent before an operation; an operation imaging system provided with an adjustable wavelength excitation light source, a high-sensitivity receiving device and a real-time image processing unit is adopted; the specific development of the vascular nerve bundle is realized by optimizing the excitation / emission wavelength and an image processing algorithm; guiding the surgical operation in real time and monitoring the signal intensity based on the fluorescent navigation image; after an operation, a multi-modal evaluation system such as three-dimensional pathological reconstruction, fluorescent marker analysis and intelligent pathological diagnosis is adopted to verify the operation effect. Through an innovative fluorescent development mechanism, an intelligent image processing technology and a multi-parameter intraoperative navigation system, accurate positioning and protection of a nerve structure in a prostatic cancer operation are realized, and the operation accuracy and the nerve retention rate are remarkably improved.

[Problem] To provide a method for producing a nerve fascicle, the method comprising efficiently elongating an axon of a nerve cell. [Solution] Nerve cells are cultured in the presence of feeder cells including at least one kind of cell selected from among angiogenic cells, perivascular cells, and oligodendrocytes.

The application relates to a Kaf electrode implanting device, which comprises a hand-held part, a transmission part and an execution part, a control unit is arranged on the hand-held part, the control unit is used for outputting operation instructions, the transmission part is used for transmitting the operation instructions to the execution part, and the execution part is used for pushing a Kaf electrode to a target area on a nerve bundle in response to the operation instructions. The application avoids the damage of nerve fibers caused by the deepening of surgical instruments, reduces the operation difficulty and time, and reduces the operation risk.

A pain management system includes: a resorbable electrode mounted on a substrate configured to be implanted on the nerve bundle of a patient, the resorbable electrode being configured to emit electrical pulses to the nerve bundle; and an electrical signal transmitter operatively and wirelessly connected with the resorbable electrode, the electrical signal transmitter configured to transmit signals to the electrode to generate electrical pulses, the electrical signal transmitter configured to be mounted on the patient's skin near the resorbable electrode.

The invention relates to the field of medical biological materials, and discloses a magnetic field guided bionic nerve bundle membrane network artificial graft and a preparation method thereof. An inner core of the magnetic-field-guided bionic nerve bundle membrane network artificial graft is an axially-oriented micron-sized fiber network, and an outer layer of the magnetic-field-guided bionic nerve bundle membrane network artificial graft is a polyethylene glycol diacrylate chitosan composite fiber layer. The bionic bundle membrane-like fiber network can realize full-time efficient repair and regeneration of peripheral neuropathy, the micron-sized distributed axial orientation fiber network provides support for cells, silk fibroin loaded on the fiber provides anchoring points for vascular endothelial cells and Schwann cells, myelination and orientated growth of axons are accelerated, and the application prospect is wide. And high-quality repair of injured / diseased nerves is realized.