11 results about "Nerve bundle" patented technology

The object of this invention is to provide a method of producing a nerve bundle including efficiently extending axons of neural cells. As a solution to accomplish this end, neural cells are cultivated in the presence of feeder cells including at least one type of cells selected from vascular component cells and perivascular cells.

A pain management system includes: a resorbable electrode mounted on a substrate configured to be implanted on the nerve bundle of a patient, the resorbable electrode being configured to emit electrical pulses to the nerve bundle; and an electrical signal transmitter operatively and wirelessly connected with the resorbable electrode, the electrical signal transmitter configured to transmit signals to the electrode to generate electrical pulses, the electrical signal transmitter configured to be mounted on the patient's skin near the resorbable electrode.

The invention relates to the technical field of medical images, in particular to a nerve anesthesia puncture auxiliary positioning method based on an ultrasonic image, which comprises the following steps: acquiring a real-time ultrasonic image of a target area; carrying out automatic identification and segmentation on a neural structure in the ultrasonic image; fusing the probe space pose data acquired by the electromagnetic positioning system with the three-dimensional coordinates of the puncture needle; projecting a neural structure position and a virtual needle insertion path guide line on augmented reality display equipment in real time; compared with the prior art which depends on manual visual inspection of an ultrasonic image to position a neural structure and has the defects of high subjectivity, high requirement on operator experience and low minor nerve tract recognition rate, the scheme adopts a deep learning model based on an improved U-Net + + architecture; millimeter-level accurate recognition and segmentation of a neural structure are achieved in combination with a multi-modal fusion enhancement technology, the definition and stability of neural development under complex anatomical conditions are remarkably improved, and a reliable anatomical basis is provided for puncture path planning.

This invention discloses a method and system for image enhancement processing of traumatic neuropathic pain, relating to the fields of data processing and artificial intelligence. Based on multi-scale Gaussian difference edge extraction and structural tensor enhancement, this invention achieves precise preservation of blurred lesion boundaries; independently extracts structural features and optimal scale edge features to solve the problem of unbalanced feature responses caused by different lesion sizes; based on dual-path orthogonal constraints combined with spatial weight modulation, it achieves complete decoupling of lesion features from normal tissue; and utilizes edge features to generate a spatial attention mask to guide the reconstruction process while maintaining the continuity of nerve bundles and avoiding noise amplification. This achieves precise preservation of lesion details, effective suppression of noise, and structural reconstruction of the continuity of nerve bundles, providing clearer and more reliable imaging evidence for clinical diagnosis.

The application discloses an esterase-responsive lipid prodrug capsaicin nanoassemblies as well as a preparation method and application thereof, the nanoassemblies are formed by self-assembly of lipid prodrug capsaicin in an aqueous medium, and the average particle size of the nanoassemblies is 50-300 nm. The nanoassemblies can efficiently penetrate a nerve bundle membrane barrier, locally form a drug depot in nerve tissue, and slowly release active capsaicin under the action of esterase, so that long-acting, safe and selective analgesia is realized, and key problems such as poor permeability of free capsaicin, severe burning pain caused by injection, and narrow treatment window are solved.

A method or actions performed by a processor of a system includes displaying a representation of multiple tracts, fibers, nerve bundles, modulation targets, or symptoms, and a representation of electrodes of a cuff lead; in response to selection of at least one of the electrodes, displaying an indication of which tracts, fibers, or nen e bundles can be activated or which modulation targets or symptoms can be affected, using the at least one selected electrode; in response to selection of one of the tracts, fibers, nerve bundles, modulation targets, or symptoms, displaying an indication of at least one of the electrodes for activating the selected tract, fiber, or nerve bundle or for affecting the selected modulation target or symptom; and, optionally, programming a stimulator to stimulate the nerve using the at least one selected electrode or the at least one indicated electrode.

A system and method for prostate cancer treatment under local anesthesia includes creating a superficial skin and subcutaneous block in a perineal area of a patient by administering a first anesthetizing agent; creating a deep nerve block under ultrasound guidance by administering a second anesthetizing agent, the second anesthetizing agent infiltrating cavernosal nerve bundle tissue and periprostatic space; and ablating prostate tissue. The office-based method, statistical models and computer generated treatment plans identify and ablate prostate tissue containing cancer through or via the perineum while preserving prostate function, and critical anatomical structures. Multiple technologies are integrated and processed to deliver a safe treatment procedure, under local anesthesia by integrating the information of magnetic resonance imaging and planning the ablative treatment using algorithms that ensure maximal precision in both killing cancerous tissue and preserving healthy tissue along with its corresponding function.

[Problem] To provide a method for producing a nerve fascicle, the method comprising efficiently elongating an axon of a nerve cell. [Solution] Nerve cells are cultured in the presence of feeder cells including at least one kind of cell selected from among angiogenic cells, perivascular cells, and oligodendrocytes.

The application relates to a Kaf electrode implanting device, which comprises a hand-held part, a transmission part and an execution part, a control unit is arranged on the hand-held part, the control unit is used for outputting operation instructions, the transmission part is used for transmitting the operation instructions to the execution part, and the execution part is used for pushing a Kaf electrode to a target area on a nerve bundle in response to the operation instructions. The application avoids the damage of nerve fibers caused by the deepening of surgical instruments, reduces the operation difficulty and time, and reduces the operation risk.

A pain management system includes: a resorbable electrode mounted on a substrate configured to be implanted on the nerve bundle of a patient, the resorbable electrode being configured to emit electrical pulses to the nerve bundle; and an electrical signal transmitter operatively and wirelessly connected with the resorbable electrode, the electrical signal transmitter configured to transmit signals to the electrode to generate electrical pulses, the electrical signal transmitter configured to be mounted on the patient's skin near the resorbable electrode.

The invention relates to the field of medical biological materials, and discloses a magnetic field guided bionic nerve bundle membrane network artificial graft and a preparation method thereof. An inner core of the magnetic-field-guided bionic nerve bundle membrane network artificial graft is an axially-oriented micron-sized fiber network, and an outer layer of the magnetic-field-guided bionic nerve bundle membrane network artificial graft is a polyethylene glycol diacrylate chitosan composite fiber layer. The bionic bundle membrane-like fiber network can realize full-time efficient repair and regeneration of peripheral neuropathy, the micron-sized distributed axial orientation fiber network provides support for cells, silk fibroin loaded on the fiber provides anchoring points for vascular endothelial cells and Schwann cells, myelination and orientated growth of axons are accelerated, and the application prospect is wide. And high-quality repair of injured / diseased nerves is realized.