7 results about "Sensory Functions" patented technology

This invention discloses a multi-sensory flexible tactile sensor, comprising a flexible cap base, multiple tactile sensing units, and multiple wires. The multiple tactile sensing units are circumferentially spaced on the outer peripheral surface of the flexible cap base. Each tactile sensing unit includes a flexible conductive layer and a flexible sensing layer. The flexible conductive layer is embedded in the flexible cap base, and the flexible sensing layer covers the flexible conductive layer and protrudes from the outer peripheral surface of the flexible cap base. The wires connect to the tactile sensing units and extend along the length of the flexible cap base. This invention also discloses an endoscope including a multi-sensory flexible tactile sensor and its state detection method. The flexible tactile sensor of this invention has multi-directional tactile sensing, instantaneous collision and continuous pressure differentiation sensing, hardness sensing, and other multi-sensory functions. Its good flexibility and conformability can adapt to the bending and movement requirements of the endoscope within the tissue being measured.

The invention belongs to the field of biomedical engineering, and discloses a function positioning system for connection of a medial thalamic pillow and an emotional cortex, which comprises the following steps of: performing near-infrared nerve stimulation on the medial thalamic pillow, and collecting an MRI (Magnetic Resonance Imaging) structure image and an MRI function image during stimulation; according to the MRI structure image, projecting a buckling back, a brain island, an amygdaloid nucleus and a subregion thereof, and a brain region adjacent to the buckling back, and respectively segmenting the buckling back, the brain island and the amygdaloid nucleus; different body emotion expression function partitions are positioned at the buckle back; positioning the internal sensory function subareas according to the subareas of the brain island; according to different subregions of the amygdala kernel, positioning the emotion function regions of the amygdala kernel; according to the MRI functional image, the activated voxel is evaluated, and according to the positions of the activated voxel in different emotional loop brain areas, the function positioning of the connection of the inner thalamic pillow and the emotional cortex is realized. According to the system, the specific topological connectivity of the inner thalamic pillow and the brain emotional cortex is realized.

This invention discloses a method and system for assessing implant-bone sensory function status. The method includes the following steps: S1. Applying a dynamic test excitation signal to a sensory measurement rod rigidly connected to the implant via a standard force generator; S2. Simultaneously acquiring the standard input force signal (F) output by the standard force generator. input ), and the implant response force signal (F) measured by the sensory measuring rod. implant S3. Response force signal (F) to the implant implant S4. Perform time-domain or frequency-domain analysis to extract at least one characteristic parameter characterizing the implant-bone sensing dynamic mechanical properties; S5. Based on the characteristic parameter, evaluate the implant-bone sensing functional state and mechanical stability.

The invention discloses a chimeric antigen receptor T cell specifically targeting FAP and application of the chimeric antigen receptor T cell in treatment of spinal cord injury. The invention finds that the FAP is a potential candidate for targeting pathological fibroblasts in a fiber scar formation pathology after spinal cord injury. The constructed FAP CAR-T cell can effectively recognize and eliminate cells expressing FAP, in mouse animal experiments, the FAP CAR-T cell not only can inhibit fiber scar formation after spinal cord injury, but also can promote movement and sensory function recovery, and a new treatment scheme and choice are provided for clinical treatment of spinal cord injury.

In various embodiments, methods are provided to improve motor function, and / or to improve motor control, and / or to improve sensory function, and / or to reduce pain in subjects with nerve root palsies (e.g., radiculopathies including, but not limited to cauda equina syndrome). In certain embodiments, methods are provided for the magnetic stimulation of the spinal cord or regions thereof to improve motor function of upper and / or lower extremities in subjects with impaired extremity motor function due to spinal cord or brain injury or pathology.

Provided is a composition for the treatment of herniated intervertebral disc or pain resulting therefrom, including a hydrogel patch, which shows the effects of improving neurological grade before and after the procedure, improving behavioral ability before and after the procedure, and recovering sensory ability, in a disc animal model. Accordingly, the composition can be useful for the prevention or treatment of the herniated intervertebral disc or pain resulting therefrom in a minimally invasive method.