14 results about "Sensory Functions" patented technology

This invention discloses a multi-sensory flexible tactile sensor, comprising a flexible cap base, multiple tactile sensing units, and multiple wires. The multiple tactile sensing units are circumferentially spaced on the outer peripheral surface of the flexible cap base. Each tactile sensing unit includes a flexible conductive layer and a flexible sensing layer. The flexible conductive layer is embedded in the flexible cap base, and the flexible sensing layer covers the flexible conductive layer and protrudes from the outer peripheral surface of the flexible cap base. The wires connect to the tactile sensing units and extend along the length of the flexible cap base. This invention also discloses an endoscope including a multi-sensory flexible tactile sensor and its state detection method. The flexible tactile sensor of this invention has multi-directional tactile sensing, instantaneous collision and continuous pressure differentiation sensing, hardness sensing, and other multi-sensory functions. Its good flexibility and conformability can adapt to the bending and movement requirements of the endoscope within the tissue being measured.

The invention relates to the technical field of medicine boxes, and discloses a medicine box special for senile diseases and having a reminding function, the medicine box comprises a shell assembly, the shell assembly comprises an outer box body, an outer cover is hinged to the outer surface of the outer box body, an inner box body is fixedly connected to the interior of the outer box body, and the interior of the inner box body is divided into four medicine storage cavities; an inner sealing cover is arranged at the top of the medicine storage cavity, a first magnet is embedded in the position, close to the edge, of the top of the outer box body, and a second magnet is embedded in the position, close to the edge, of the bottom of the outer cover. The multi-mode reminding system is constructed by integrating the clock chip, the voice module, the weighing module and the vibration motor, voice broadcast, corresponding LED light indication and synchronous vibration prompt are triggered at the preset medicine taking time, dynamic medicine quantity monitoring is combined, medicine shortage warning is automatically triggered when the medicine remaining amount is insufficient, and the medicine taking efficiency is improved. The problems of missing taking and wrong taking caused by memory deterioration or sensory function decline of old people are effectively solved, and the medication compliance and safety are remarkably improved.

The invention belongs to the field of biomedical engineering, and discloses a function positioning system for connection of a medial thalamic pillow and an emotional cortex, which comprises the following steps of: performing near-infrared nerve stimulation on the medial thalamic pillow, and collecting an MRI (Magnetic Resonance Imaging) structure image and an MRI function image during stimulation; according to the MRI structure image, projecting a buckling back, a brain island, an amygdaloid nucleus and a subregion thereof, and a brain region adjacent to the buckling back, and respectively segmenting the buckling back, the brain island and the amygdaloid nucleus; different body emotion expression function partitions are positioned at the buckle back; positioning the internal sensory function subareas according to the subareas of the brain island; according to different subregions of the amygdala kernel, positioning the emotion function regions of the amygdala kernel; according to the MRI functional image, the activated voxel is evaluated, and according to the positions of the activated voxel in different emotional loop brain areas, the function positioning of the connection of the inner thalamic pillow and the emotional cortex is realized. According to the system, the specific topological connectivity of the inner thalamic pillow and the brain emotional cortex is realized.

The present application relates to the field of biophysics technology, especially to a kind of calculation method for considering the contribution of biological activity to human sensory function.It includes a new type of calculation analysis model for considering the motion of cochlear acoustic function key support structure of biological activity based on physical mechanics principle.The present application deduces the periodic variation of the stiffness of basilar membrane in space and time while coupled with lymphatic fluid motion equation, and is solved.I.e.develop a kind of calculation method for considering the contribution of biological activity to human sensory function, and the correctness of the analytical method is verified by computer numerical simulation.The method established by the present application is easy to operate, feasible, efficient and accurate.

The invention provides a peripheral nerve rehabilitation evaluation system and method based on a multi-modal large model, and the system comprises a data preprocessing module and a multi-modal data fusion module which are used for extracting key features from data of different modals; fusing the features of different modes by adopting a multi-feature fusion method; using the fused feature data to train a multi-modal large model; the trained multi-modal large model is evaluated by using an independent test data set; the rehabilitation evaluation module is used for evaluating the movement function of the patient according to the biomechanical data and the video image data; and evaluating the sensory function of the patient in combination with the surface electromyogram signal and the electroencephalogram signal. According to the technical scheme, data fusion and analysis are carried out based on the multi-modal large model, the rehabilitation condition of the patient can be evaluated more accurately, and the accuracy and reliability of evaluation are improved.

This invention discloses a method and system for assessing implant-bone sensory function status. The method includes the following steps: S1. Applying a dynamic test excitation signal to a sensory measurement rod rigidly connected to the implant via a standard force generator; S2. Simultaneously acquiring the standard input force signal (F) output by the standard force generator. input ), and the implant response force signal (F) measured by the sensory measuring rod. implant S3. Response force signal (F) to the implant implant S4. Perform time-domain or frequency-domain analysis to extract at least one characteristic parameter characterizing the implant-bone sensing dynamic mechanical properties; S5. Based on the characteristic parameter, evaluate the implant-bone sensing functional state and mechanical stability.

To provide a sensitivity improvement device which can improve a sensing function of oral cavity and pharynx using a phenomenon called stochastic resonance.SOLUTION: A sensitivity improvement device of the present invention includes an actuator 14 for generating a noise vibration. By applying the noise vibration to a skin of head and neck or a tongue of a biological body, the sensing function of the oral cavity or a pharynx is improved using a phenomenon called stochastic resonance. Further, threshold value setting means 20 is provided for setting a vibration level of the noise vibration. The threshold value setting means 20 applies different vibration levels to a user, causes the user to input the stimulated vibration level at which the noise vibration is sensed and a non-stimulated vibration level at which the noise vibration is not sensed, and sets a threshold value specific to the user based on the input stimulated vibration level and the non-stimulated vibration level.SELECTED DRAWING: Figure 1

In various embodiments, methods are provided to improve motor function, and / or to improve motor control, and / or to improve sensory function, and / or to reduce pain in subjects with nerve root palsies (e.g., radiculopathies including, but not limited to cauda equina syndrome). In certain embodiments, methods are provided for the magnetic stimulation of the spinal cord or regions thereof to improve motor function of upper and / or lower extremities in subjects with impaired extremity motor function due to spinal cord or brain injury or pathology.

The application provides an upper gastrointestinal tract transport function detection device, which is provided with a functional device on a flexible core body; the functional device comprises an embeddable sensor, an impedance electrode, a microprocessor and a wireless module; the flexible core body can be swallowed through the oral cavity or inserted into the gastrointestinal tract for transport function detection, transport characteristic parameter collection is completed, and detection of different aspects of gastrointestinal function is realized; the embeddable sensor collects data through a storage chip or a matched external wireless receiver. The application adopts a bionic structure design, has the characteristics of being easy to swallow and inserted into the esophagus, can detect key parameters including axial pressure, acceleration and orientation, and further calculates various transport indexes and pressures at specific times and positions through the key parameters, solves the problems of function detection of esophageal tortuosity, transport acceleration, speed and trajectory, and meets the functional requirements of organic lesion and sensory function diagnosis by obtaining the information and the esophageal pressure and symptom related characteristics.

The invention discloses an application of psoralen in preparation of a medicine for preventing and treating cerebral ischemia-reperfusion injury. The invention firstly proposes and verifies that the psoralen can prevent and treat the cerebral ischemia reperfusion injury, including cerebral infarction, motor function injury, sensory function retardation or disappearance, equilibrium dysfunction and neurological function injury represented by reflex deficiency, and provides a new direction for mechanism research and treatment of the cerebral ischemia reperfusion injury.

The invention discloses a chimeric antigen receptor T cell specifically targeting FAP and application of the chimeric antigen receptor T cell in treatment of spinal cord injury. The invention finds that the FAP is a potential candidate for targeting pathological fibroblasts in a fiber scar formation pathology after spinal cord injury. The constructed FAP CAR-T cell can effectively recognize and eliminate cells expressing FAP, in mouse animal experiments, the FAP CAR-T cell not only can inhibit fiber scar formation after spinal cord injury, but also can promote movement and sensory function recovery, and a new treatment scheme and choice are provided for clinical treatment of spinal cord injury.

In various embodiments, methods are provided to improve motor function, and / or to improve motor control, and / or to improve sensory function, and / or to reduce pain in subjects with nerve root palsies (e.g., radiculopathies including, but not limited to cauda equina syndrome). In certain embodiments, methods are provided for the magnetic stimulation of the spinal cord or regions thereof to improve motor function of upper and / or lower extremities in subjects with impaired extremity motor function due to spinal cord or brain injury or pathology.

Provided is a composition for the treatment of herniated intervertebral disc or pain resulting therefrom, including a hydrogel patch, which shows the effects of improving neurological grade before and after the procedure, improving behavioral ability before and after the procedure, and recovering sensory ability, in a disc animal model. Accordingly, the composition can be useful for the prevention or treatment of the herniated intervertebral disc or pain resulting therefrom in a minimally invasive method.

The invention provides a self-powered sensory nerve morphology system integrating multiple perception functions and a preparation method thereof, belongs to the technical field of bionic nerve morphology systems, and aims to solve the technical problem that a self-powered bionic nerve component is single in perception function. The self-energized sensory neuromorphic system comprises a lower substrate, a lower electrode layer, a photoelectric sensitive signal processing layer, an upper electrode layer and an upper substrate, and the photoelectric sensitive signal processing layer is prepared by mixing a high-dielectric-property insulating material and a light-absorbing material. The photoelectric sensitive signal processing layer in the self-energized sensory neuromorphic system can sense touch, hearing and the like and can also sense illumination to simulate a biological visual function, so that a single device is promoted to simulate a biological multi-sensory function. The device simultaneously realizes touch, auditory and visual perception calculation functions, and promotes the artificial intelligence technology to realize more efficient multi-application scene and multi-perception interaction, thereby providing a more efficient and rapid development channel for the artificial intelligence technology.