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227 results about "Pain sensations" patented technology

Pain sensation - a somatic sensation of acute discomfort; "as the intensity increased the sensation changed from tickle to pain". painful sensation, pain. somaesthesia, somatesthesia, somatic sensation, somesthesia - the perception of tactual or proprioceptive or gut sensations; "he relied on somesthesia to warn him of pressure changes".

Cold/hot pain stimulation system

The invention discloses a cold / hot pain stimulation system, which mainly solves the problem that the laser stimulation equipment in the prior art cannot refrigerate and is complex in operation and high in cost in a nuclear magnetic environment. The cold / hot pain stimulation system comprises a cold / hot stimulation head (1), a protective net (2), a heat radiation water tank (3), a water pump (4), a water storage tank (5), an embedded type control module (6) and an upper computer, wherein the cold / hot stimulation head (1), the heat radiation water tank (3), the water pump (4) and the water storage tank (5) are connected with each other in sequence to form a water circulation system through water pipes; the cold / hot stimulation head (1) is connected with the upper computer (7) through the embedded type control module (6); the embedded type control module (6) controls the cold / hot stimulation head (1) to stimulate human skin according to the stimulation temperature set by the upper computer; and the actual stimulation temperature and pain sensation scores are transmitted to the upper computer (7) for storage and display through the embedded type control module (6). The cold / hot pain stimulation system disclosed by the invention is easy in operation and safe in use, and can be used for studying the pain sensation and evaluating pain relieving effect in a nuclear magnetic environment.
Owner:XIDIAN UNIV

Methods and compositions for studying, imaging, and treating pain

Saxitoxin analogue compounds, compositions, pharmaceutical compositions, methods of synthesis of saxitoxin analogues, methods of imaging, methods of treatment, including methods of treating pain, are provided. Saxitoxin (STX), gonyautoxin (GTX), and zetekitoxin, and variant STX compounds bind to sodium channels and are effective to reduce or block flow of sodium ions through such channels. Such channel block affects nerve and muscle action, and may be effective to reduce or block pain sensations, relax muscles, reduce muscle spasm, and reduce wrinkles. STX analogue binding to sodium channels may also be useful to locate, image, or mark sodium channels, and so be useful in studying sodium channels and sodium channel disorders, and in the diagnosis and treatment of patients suffering from sodium channel disorders. In embodiments, the variant STX compounds include conjugates having increased serum half-life as compared to STX when administered to a subject. In embodiments, the present disclosure provides a method for alleviating pain in a subject in need of treatment, the method comprising administering to the subject an effective amount of a saxitoxin analogue compound, or a pharmaceutically acceptable salt, isomer, tautomer or prodrug thereof, whereby pain in said subject is alleviated.
Owner:THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV

Anesthesia puncture fixing robot for pain department

The invention discloses an anesthesia puncture fixing robot for the pain department. The anesthesia puncture fixing robot comprises a base, wherein a stand column is abutted against the upper end of the base; a fixing block is fixed to the upper end of the stand column; a sliding groove is arranged on the bottom of the stand column; the fixing block is abutted against the inner wall of the sliding groove; the stand column is a U-shaped column; a fixing rod is fixed to the upper end of the stand column; a rotating block is rotatably connected to the circumferential side wall of the fixing rod; the rotating block is an L-shaped block; a puncture block is fixed to the bottom of the rotating block; a lead screw is rotatably connected to the inner wall of the puncture block through a bearing; and a mounting groove is arranged on the inner bottom of the puncture block in a penetrating mode. The anesthesia puncture fixing robot for the pain department has the advantages that a motor electrically drives a sliding plate to move, a puncture needle and a sliding plate can move at the same time under the action of an arc-shaped stop block and a protruding block, so that stable and continuous insertion of the puncture needle is achieved, manual supporting is not needed, the stability of the puncture needle in an insertion process can be guaranteed, pain feeling caused by buffering can be effectively reduced, and the anesthesia puncture fixing robot can be conveniently used for anesthesia in the pain department.
Owner:康敏
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