The invention discloses a distributed integrated modular avionic system hybrid dynamic reconfiguration system and method. The distributed integrated modular avionic system hybrid dynamic reconfiguration system at least comprises a first operation module, a second operation module, a third operation module, a fourth operation module, a fifth operation module, a first TTE exchanger and a second TTE exchanger, wherein the first operation module, the second operation module, the third operation module, the fourth operation module and the fifth operation module are connected through the first TTE exchanger and the second TTE exchanger, and the first TTE exchanger and the second TTE exchanger execute the TTE protocol. According to the protocol, in the communication process, a global clock is adopted for starting data receiving and transmitting, and the operation of each TTE exchanger and each operation module is only related with the global time. One operation module is set as the main reconfiguration management module to manage the remote reconfiguration work of the whole system in a uniform mode, and another operation module is set as the backup module.