44 results about "Neurovascular bundle" patented technology

A tissue protective system and method having particular application in thermoablative surgical therapies where heat or cold is used to create a kill zone for treating cancer cells as well as malignant or benign tumors in a targeted internal tissue area (e.g., the prostate) of a patient while sparing an adjacent benign internal tissue area (e.g., a neurovascular bundle). One of a hollow sheath or a balloon that is carried by a balloon catheter is located within an access opening that is made by a needle trocar inserted between the targeted tissue area in need of treatment and the benign tissue area to be protected in order to hold the protected tissue area off the targeted tissue area and away from the lethal temperature of the kill zone. The balloon of the balloon catheter is inflated in the access opening via a balloon channel which runs longitudinally through the catheter. At least one temperature sensor is mounted on the balloon and responsive to the temperature near the benign tissue area to be protected. Heat or cold is provided to the balloon from a heating wire or a circulating fluid, depending upon the temperature that is sensed by the temperature sensor.

An apparatus and method for protecting the neurovascular bundle during cryoablation of tissues of the prostate by heating the vicinity of the neurovascular bundle while cooling pathological tissues of a prostate to cryoablation temperatures, thereby cryoablating pathological tissues while protecting the neurovascular bundle from damage. A cryoprobe operable to cool a distal operating tip while heating a proximal shaft is presented.

A curved paddle electrode allows the electrode to be placed over a relatively flat or oval shaped nerve bundle attached to fascia tissue without having to separate the nerve bundle from the fascia tissue. The electrode includes at least one suture hole that allows the electrode to be held in place over the nerve bundle through a clip-on stitch, or equivalent. In one embodiment, the curved paddle electrode provides a tripolar electrode configuration that allows three spaced-apart parallel electrode contacts to be positioned transverse to a target nerve bundle. Such electrode configuration allows bipolar or tripolar stimulation to occur. Other embodiments employ less or more than three electrode contacts. A preferred application of the curved paddle electrode is for the treatment of erectile dysfunction (ED), where the electrode is placed over the neurovascular bundle attached to the rectal fascia tissue near the rectum.

A dental implantation system is for securing a dental prosthesis in a patient's jawbone including an alveolar bone, a basal bone adjacent the alveolar bone, and a neurovascular bundle running through the jawbone. The dental implantation system may include a dental implant fixture having an elongate shape and including an upper portion to be positioned in the alveolar bone to receive the dental prosthesis and defining a first axis. The dental implant fixture may also include a lower portion to be positioned in the basal bone and defining a second axis. The dental implant fixture may further include an intermediate offset-defining portion between the upper portion and the lower portion to define an offset between the first axis and the second axis so that the lower portion avoids the neurovascular bundle.

A tissue protective system and method having particular application in thermoablative surgical therapies where heat or cold is used to create a kill zone for treating cancer cells as well as malignant or benign tumors in a targeted internal tissue area (e.g., the prostate) of a patient while sparing an adjacent benign internal tissue area (e.g., a neurovascular bundle). One of a hollow sheath or a balloon that is carried by a balloon catheter is located within an access opening that is made by a needle trocar inserted between the targeted tissue area in need of treatment and the benign tissue area to be protected in order to hold the protected tissue area off the targeted tissue area and away from the lethal temperature of the kill zone. The balloon of the balloon catheter is inflated in the access opening via a balloon channel which runs longitudinally through the catheter. At least one temperature sensor is mounted on the balloon and responsive to the temperature near the benign tissue area to be protected. Heat or cold is provided to the balloon from a heating wire or a circulating fluid, depending upon the temperature that is sensed by the temperature sensor.

An implantable device and method for managing a patient's erectile dysfunction, wherein the device generally comprises: at least one power source member that is adapted to be implanted in the patient's lower abdominal wall; at least one pulse generating member that is adapted to be implanted in the patient's lower abdominal wall; and at least one electrode that is adapted to be implanted at the suprapubic level of the patient's neurovascular bundle of the phallus, is connected to said power source member and pulse generating member, and is adapted to electrically stimulate the neurovascular bundle upon selective activation by the patient.

A method for treating pain or discomfort in a patient is disclosed. The method comprises stimulating a cranial nerve with an electrical signal. The pain or discomfort may be a withdrawal symptom. The cranial nerve may be in an auricular area of the patient. The cranial nerve may be cranial nerve V, cranial nerve VII, cranial nerve IX, cranial nerve X, or branches of greater and lesser occipital nerves thereof and their associated neurovascular bundles. The withdrawal symptom may result from cessation of an opioid. The method may further comprise administering a secondary drug treats one or more of the withdrawal symptoms and addiction. The secondary drug may be administered about one day to about one week after initiating the stimulating step.

An implantable device and method for managing a patient's erectile dysfunction, wherein the device generally comprises: at least one power source member that is adapted to be implanted in the patient's lower abdominal wall; at least one pulse generating member that is adapted to be implanted in the patient's lower abdominal wall; and at least one electrode that is adapted to be implanted at the suprapubic level of the patient's neurovascular bundle of the phallus, is connected to said power source member and pulse generating member, and is adapted to electrically stimulate the neurovascular bundle upon selective activation by the patient.

An apparatus and method for protecting the neurovascular bundle during cryoablation of tissues of the prostate by heating the vicinity of the neurovascular bundle while cooling pathological tissues of a prostate to cryoablation temperatures, thereby cryoablating pathological tissues while protecting the neurovascular bundle from damage. A cryoprobe operable to cool a distal operating tip while heating a proximal shaft is presented.

The invention discloses a nerve protection guide plate for mandible osteotomy. The guide plate is integrally attached to the bone face of the mandible, an arc guide area is arranged on the edge of the guide plate, and the arc and the length of the guide area are matched with the arc and the length of the inferior alveolar nerve canal. The nerve protection guide plate for mandible osteotomy enables osteotomy to be carried out more easily, and is convenient for an operator to operate; osteotomy under guidance of the guide plate allows a mandible diseased region to be cut off precisely along the boundary, residual is avoided, and the risk of postoperative recurrence is effective reduced; osteotomy under guidance of the guide plate can effectively preserve the inferior alveolar neurovascular bundle, the serious complications, such as postoperative affected side chin lip skin numbness, tooth remaining on the affected side lower jaw, nerve loss of alveolar bone and the like, ischemia, inactivation and even necrosis, due to cutting or accidentally injure are avoided, and the postoperative life quality of patients is improved.

An energy diffusing pad insertable within a glove. The pad includes a resilient material having a first and a second surface, and a front and rear portion. The first surface is positionable against a user's palm such that when the pad is aligned over the user's palm, the first surface of the cushion contacts at least the thenar and hypothenar eminences of a user's palm while not contacting the user's Median and Ulnar neurovascular bundles. The glove may include a pouch to retain the pad while in use. When in use, the pad is positioned over the user's palm, where the pad forms a bridge over the raised, bony thenar and hypothenar eminences of a user's palm. The pad diffuses the pressure of the grasped object away from the region between the thenar and hypothenar eminences, thus protecting the Median and Ulnar neurovascular bundles. A cushioned insert may be included within a portion of the pad to provide additional cushioning and protection of the Median and Ulnar nerves.

A method for treating pain or discomfort in a patient is disclosed. The method comprises stimulating a cranial nerve with an electrical signal. The pain or discomfort may be a withdrawal symptom. The cranial nerve may be in an auricular area of the patient. The cranial nerve may be cranial nerve V, cranial nerve VII, cranial nerve IX, cranial nerve X, or branches of greater and lesser occipital nerves thereof and their associated neurovascular bundles. The withdrawal symptom may result from cessation of an opioid. The method may further comprise administering a secondary drug treats one or more of the withdrawal symptoms and addiction. The secondary drug may be administered about one day to about one week after initiating the stimulating step.

The various embodiments of the present invention provide an inferior alveolar nerve (IAN) protector instrument for proper protection of neurovascular bundle and to prevent the traumatic injuries during oral and maxillofacial surgeries. The IAN protector instrument made of stainless steel has a shank, a blade and a handle. The shank is formed to serve as a soft tissue flap retractor while supporting the blade. The handle is designed with a finger rest for more control and in the pear shape for palm grasp. The shank is bent twice at 120 degrees. The blade is curved with a radius of curvature equal to ⅙-⅛ of a complete circle. The dissecting edge and both lateral line angles are rounded to avoid untoward cutting. The instrument is designed separately for right and left sides of the mouth.

A dental implantation system is for securing a dental prosthesis in a patient's jawbone including an alveolar bone, a basal bone adjacent the alveolar bone, and a neurovascular bundle running through the jawbone. The dental implantation system may include a dental implant fixture having an elongate shape and including an upper portion to be positioned in the alveolar bone to receive the dental prosthesis and defining a first axis The dental implant fixture may also include a lower portion to be positioned in the basal bone and defining a second axis. The dental implant fixture may further include an intermediate offset-defining portion between the upper portion and the lower portion to define an offset between the first axis and the second axis so that the lower portion avoids the neurovascular bundle.

The invention discloses a positioning device for a mandibular ramus osteotomy. The positioning device has two structures: according to the first structure, the positioning device comprises a first main rod, a subordinate rod, a first connector, a positioning rod, a first limiter and an intra-bone nail which takes a fixing effect during an operation; and according to the second structure, the positioning device comprises a second main rod, a guide plate, a first branch rod, a second branch rod, a second limiter, a third limiter, a second connector, a third connector and an intra-bone nail which takes a fixing effect during the operation. When the positioning device is used, an operation incision line can be kept away from mandibular nerve and mandibular nerve tube, and the location of an osteotomy line can be directly and accurately determined; and during the operation, injury of inferior alveolar nerve vessel bundles can be avoided, and a sufficient width with proximal segment can be guaranteed as well.

Electrical stimulation of neural activity in the neural innervation of the spleen that is associated with neurovascular bundles provides a useful way to treat acute medical conditions, such as trauma, hemorrhaging and shock.

The invention provides an intraoperative neurovascular bundle identification and injury early warning method and system based on artificial intelligence. According to the method, real-time image data are acquired through a multi-modal imaging device, multi-scale blood vessel features are extracted by adopting a three-stage cascade adaptive path convolution (APC) module, the long-range topology perception capability is enhanced in combination with a local-global interaction module (LGIM), global features are integrated by utilizing a cross-scale deformable convolutional network (CSDCN), and dimensions are compressed through a multi-branch feature distillation module (MFDM). And the multi-task classifier synchronously outputs the category, position and injury risk assessment of the blood vessel bundle, and real-time multi-modal early warning is realized through dynamic confidence threshold and mahalanobis distance anomaly detection. According to the invention, the accuracy and real-time performance of intraoperative nerve and blood vessel protection are obviously improved.

Electrical stimulation of neural activity in the neural innervation of the spleen that is associated with neurovascular bundles provides a useful way to treat acute medical conditions, such as trauma,hemorrhaging and shock.

Stimulation of neural activity in a nerve supplying the spleen, wherein the nerve is associated with a neurovascular bundle, can modulate pro- and anti-inflammatory molecules levels, thereby reducing inflammation and providing ways of treating inflammatory disorders. The invention provides improved ways of treating inflammatory disorders which minimize off-target effects.

The present inventive concept relates to a physical therapy device designed to isolate and strengthen ankle dorsiflexors and related muscle groups without compressing major neurovascular bundles that cross the ankle joints. The present inventive concept combines fulcrums along the medial and lateral aspects of the ankle with resistance along the posterior aspect of the ankle to achieve mobility and resistance against motion during use. Benefits of the present inventive concept include improved ankle stability and dexterity, mitigation of ankle injuries, and prevention of neurovascular compression around the ankle during use.

Electrical stimulation of neural activity in the neural innervation of the spleen that is associated with neurovascular bundles provides a useful way to treat acute medical conditions, such as trauma, hemorrhaging and shock.

Electrical stimulation of neural activity in the neural innervation of the spleen that is associated with neurovascular bundles provides a useful way to treat acute medical conditions, such as trauma, hemorrhaging, shock, acute respiratory distress syndrome (ARDS), severe respiratory distress syndrome (SARS), and coronavirus disease 19 (COVID-19).

Stimulation of neural activity in a nerve supplying the spleen, wherein the nerve is associated with a neurovascular bundle, can modulate pro- and anti-inflammatory molecules levels, thereby reducinginflammation and providing ways of treating inflammatory disorders. The invention provides improved ways of treating inflammatory disorders which minimize off-target effects.

A method for delivering ultrasound therapy using open loop control includes inserting a distal tip of a therapeutic ultrasound applicator into the urethra of a patient, the distal tip including an ultrasound transducer; acquiring ultrasonic images of the urethra and the prostate of the patient by using an ultrasonic imaging probe; aligning the distal tip of the therapeutic ultrasound applicator with the prostate of the patient using the ultrasound image; therapeutic ultrasound energy is delivered with the ultrasound transducer to the prostate of the patient according to a treatment plan that includes a predetermined limited angular range for therapeutic ultrasound energy that avoids the rectum, neurovascular bundle of the patient, where the therapeutic ultrasound energy is transmitted to the prostate of the patient using the ultrasound transducer. The therapeutic ultrasound is transmitted without temperature feedback data.

A penile prosthesis (1) comprising a main body (10) made of biocompatible material and comprising a first seat (4) for housing the urethra (U) of a user and a second seat (5) for housing the neurovascular bundle of the penis of said user, said first seat (4) being made from a part of said main body (10) opposite to the part in which said second seat (5) is made.

Stimulation of neural activity in a nerve supplying the spleen, wherein the nerve is associated with a neurovascular bundle, can modulate pro- and anti-inflammatory molecules levels, thereby reducing inflammation and providing ways of treating inflammatory disorders. The invention provides improved ways of treating inflammatory disorders which minimize off-target effects.

Electrical stimulation of neural activity in the neural innervation of the spleen that is associated with neurovascular bundles provides a useful way to treat acute medical conditions, such as trauma, hemorrhaging and shock.

Stromal Derived Factor-1 (SDF-1) is a small, naturally occurring, potent chemokine with inherent angiogenic, neurogenic, anti-apoptotic protein, which is also a potent stem cell chemoattractant, cardiovascular disease, and other metabolic disturbances. The present invention provides methods for treating erectile dysfunction in a male subject comprising administering to the major pelvic ganglion supplying the cavernous nerves subject compositions comprising SDF-1. SDF-1 promotes stem cell activation, to the major pelvic ganglion supplying the cavernous nerves, helps cell preservation, and prevents adverse penile remodeling. It can be administered as a protein or by gene therapy including but not limited to plasmid DNA, viral transduction, or nanoparticle delivery directly to the penis or to the neurovascular bundle or other pelvic nerve structures during the time of surgery, or before injury, or to treat existing erectile dysfunction.

A probe useful for introducing therapeutic materials between the neural sheath and contained neurovascular tissue provides a near field imaging device permitting final positioning of the probe to be conducted with submillimeter accuracy and a vacuum channel allowing the probe to be attached to the neural sheath to withdraw it and provide a defect through which therapeutic agents can be introduced.

The present invention relates to a navigation system (1000) and associated method for assisting a user navigating a surgical tool during a medical intervention carried out on a patient (10) previously equipped with at least one fiducial (20) located on a specific body part (30). The navigation system and method combine preoperative and intraoperative information in real-time so as to generate a current augmented 3D model of the specific body part and a current virtual tool localization to assist the user during the medical intervention. The invention provides a GPS-like surgical navigation system (1000), dynamically updating a patient-specific 3D model (i.e. current augmented 3D model) in real time during soft-tissue procedures, ensuring preservation of critical neurovascular bundles.