Treatment of acute medical conditions

一种医学、急性的技术，应用在治疗急性医学病况的装置领域，能够解决尚未研究脾神经刺激促存活效应等问题

Pending Publication Date: 2020-10-16
GALVANI BIOELECTRONICS LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the pro-survival effects of splenic nerve stimulation in acute medical conditions have not been studied

Method used

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  • Treatment of acute medical conditions
  • Treatment of acute medical conditions
  • Treatment of acute medical conditions

Examples

Experimental program
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Embodiment Construction

[0020] Nerves that supply the spleen

[0021] Innervation of the spleen is predominantly sympathetic or noradrenergic, with peptide neurons likely representing the majority of the remaining neurons. The human spleen is primarily innervated by the splenic plexus surrounding the splenic artery. The splenic artery is covered by nervous tissue that originates from the celiac plexus and continues to the spleen as the splenic plexus and splenic artery. The splenic plexus enters the spleen at the hilus, where the splenic artery bifurcates at terminal branches, and the splenic plexus continues with these branches into the parenchyma of the spleen.

[0022] The splenic plexus includes several fascicles that bypass the main splenic artery from the celiac artery to the spleen, each fascicle containing a small bundle of nerve fibers. The nerve cluster that bypasses the splenic nerve (or known as the periarterial nerve cluster) is referred to herein as the splenic artery nerve.

[0023...

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PUM

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Abstract

Electrical stimulation of neural activity in the neural innervation of the spleen that is associated with neurovascular bundles provides a useful way to treat acute medical conditions, such as trauma,hemorrhaging and shock.

Description

technical field [0001] The present invention relates to the treatment of acute medical conditions. More specifically, the present invention relates to devices, systems and methods for treating acute medical conditions. Background technique [0002] An acute medical condition as referred to herein refers to a rapid deterioration of the physiological state of a subject, which may be life threatening if not treated in time. Examples include trauma, sepsis, bleeding, severe hemophilia, severe lupus flare, severe Crohn's disease flare, allogeneic / autograph rejection, anaphylaxis and endotoxic shock. Therefore, these subjects required urgent medical attention to relieve suffering and minimize the risk of morbidity and mortality. Treatment of acute medical conditions varies by disease and, depending on the severity of the disease, these treatments are often unsuccessful. [0003] In contrast, chronic medical conditions are those characterized by a prolonged clinical course durin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N1/36A61B5/0408A61N1/05A61B5/021A61B5/024
CPCA61B5/021A61B5/02405A61B5/026A61B5/0816A61B5/4836A61N1/0553A61N1/0556A61N1/36017A61N1/36021A61N1/36053A61N1/36057A61N1/36071A61N1/36114A61N1/36135A61N1/36171A61N1/36185A61N1/3606A61N1/205A61N1/3616
Inventor D·J·周M·多内加I·古普塔
Owner GALVANI BIOELECTRONICS LTD
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