10 results about "Spinal Meninges" patented technology

The present application belongs to the technical field of medical devices, and relates to medical consumables for treating spinal cord injury, in particular to a double-layer core-shell structure artificial fiber dura mater for spinal cord injury and a preparation method thereof. The double-layer core-shell structure artificial fiber is used to form a film structure, the double-layer core-shell structure artificial fiber is composed of an outer shell structure and an inner core structure, the material of the outer shell structure is composed of PLGA and PEG, the outer shell structure is loaded with NM, the material of the inner core structure is PLA, and the inner core structure is loaded with NT3. The double-layer core-shell structure artificial fiber dura mater provided by the present application has the advantages of reducing spinal cord edema, preventing fiber adhesion, improving the microenvironment, promoting the repair of spinal cord injury, and the like.

The utility model discloses a spinal cord semi-cutting positioning device with a dura mater protection function, which comprises a semi-cutting positioning structure and a dura mater protection sheet, and is characterized in that the semi-cutting positioning structure comprises a mounting frame, a lifting driving module mounted on the mounting frame and a positioning guide pin mounted below a telescopic rod of the lifting driving module; the lifting driving module drives the positioning guide pin to lift; the dura mater protection sheet is in a lifting hook shape, an inner hook section and an outer arm section integrally connected with the inner hook section are formed, a depressed position of the inner hook section is a marrow containing groove so that the dura mater can be cut open, the dura mater protection sheet enables the inner hook section to stretch into an incision, after the spinal cord is placed in the marrow containing groove, the lifting driving module drives the positioning guide needle to descend, and then the dura mater is cut. The positioning guide needle is inserted into a central shaft of the spinal cord until the positioning guide needle abuts against the marrow containing groove. When the positioning guide needle punctures the spinal cord and the scalpel cuts down along the positioning guide needle, the dura mater can be protected by the dura mater protection sheet.

The invention relates to the field of medical auxiliary instruments, in particular to a spinal endoscopic dura mater retraction device which comprises a puncture component, and the puncture component is used for percutaneous puncture to the position close to a spinal canal dura mater; a suspension part is arranged in the puncture part, and the suspension part is used for extending out of the puncture part and being connected with the cut edge of the dura mater. An operation part is further arranged on the puncture part, and the operation part is used for adjusting the retraction force applied to the dural mater by the suspension part; by controlling the operation part, the suspension part is fixed and retracts the dura mater to expose the spinal cord tissue. Through the integration of puncture, suspension and operation components, the traction of the dura mater under the minimally invasive condition of the spine endoscope is realized.

The utility model discloses a channel wire pusher, which comprises a rod part welded at one end of a handle part, claw-shaped pushing hand parts used for pushing wires are distributed at the top end of the rod part, an obtuse angle is formed between the rod part and the handle part, the included angle between every two claw-shaped pushing hand parts is 30 degrees, the included angle between the handle part and the rod part is 160 degrees, and the rod part is connected with the handle part. The number of the claw-shaped pushing hand parts is three, the length of each claw-shaped pushing hand part is 0.4 cm, the diameter of each claw-shaped pushing hand part is 0.2 cm, the length of each handle part is 4 cm, the diameter of each handle part is 1 cm, and the length of each rod part is 15 cm, and the diameter of each rod part is 0.3 cm. The device has the advantages of being small and exquisite, free of surgical view shielding, wide in application range, firm in knotting and the like, assists in dura mater suturing in the spinal microchannel surgery, reduces cerebrospinal fluid leakage after the surgery, and improves the working efficiency. And therefore, the novel medical infusion support disclosed by the utility model has a good use effect.

The invention provides a construction method of a spinal cord injury animal model for maintaining the integrity of subarachnoid space, which comprises the following steps: adopting a mammal with spinal cord injury, clamping and closing the opening of the dura mater of the mammal, dripping biological glue in alignment with the clamped and closed position, and suturing after the biological glue becomes frost and the dura mater is adhered together. The invention also provides application of the spinal cord injury animal model for maintaining the integrity of the subarachnoid space in research on motor function, nervous tissue recovery or tissue morphology recovery of animals after spinal cord injury. The application shows that after experimental spinal cord injury is caused, the motion function and histomorphological recovery of a mouse can be improved by tightly suturing the dura mater.

The application belongs to the technical field of biomedical experimental animal model construction, and provides a rat severe spinal cord injury immediate decompression model construction method. The method establishes a standardized surgical procedure, including minimally invasive exposure through the paraspinal muscle gap, precise dura mater incision, warm saline low-pressure lavage debridement, and strict dura mater suture repair. The method realizes immediate and effective reduction of intrathecal pressure, removal of harmful substances in the injury area, and stabilization of the local microenvironment after severe spinal cord injury. The application solves the problems of instability, poor repeatability, and difficulty in simulating the clinical decompression effect caused by the non-standard dura mater incision, uncontrollable lavage, and high risk of secondary injury in the prior art. The model constructed by the method is highly standardized and has strong repeatability, and is suitable for in-depth study of the neuroprotective mechanism of dura mater incision decompression treatment for spinal cord injury.

The utility model discloses an artificial ligamentum flavum complex which comprises an artificial ligament and two fixing seats, and the two ends of the artificial ligament are fixedly connected with the two fixing seats respectively. Screw holes are formed in the two fixing seats, the two fixing seats are fixedly connected with the spine by installing screws into the respective screw holes, and the bone contact surfaces at the bottoms of the two fixing seats are provided with micropore structures. When the artificial ligamentum flavum complex is installed on the spine, the artificial ligamentum flavum complex can replace the cut ligamentum flavum to maintain the mechanical stability of the spine and cover the dura mater to reduce postoperative dura mater scars. Therefore, the artificial ligamentum flavum complex can replace ligamentum flavum removed in the operation, improve the stability of the spine of a patient, reduce postoperative spine instability, protect spinal canal duramater and nerves, reduce scar adhesion and improve the postoperative clinical effect.

The invention belongs to the technical field of biomedical materials, and discloses preparation of a low-swelling medical tissue sealant and application of the low-swelling medical tissue sealant in dura mater repair. The invention discloses a sealant. The sealant is prepared from the following raw materials: multi-arm polyethylene glycol active ester and aminated gelatin. The invention provides a sealant. The sealant is formed by crosslinking multi-arm polyethylene glycol active ester and aminated gelatin through amido bonds. The sealant has the advantages of rapid gelling, high mechanical strength, strong tissue adhesion, ultralow swelling ratio, controllable degradation and excellent biocompatibility. The sealant can realize in-situ sealing and repairing of dura mater injury and prevent leakage of cerebrospinal fluid, has antibacterial, anti-infection and nerve protection effects, is suitable for repairing of dura mater and dura mater, and is especially suitable for minimally invasive neurosurgery.

The application relates to the technical field of medical devices, and discloses an ultrasound-guided pressure monitoring epidural anesthesia positioning device, which comprises a placing shell, an upper tray and a lower tray arranged in the placing shell, and a puncture component comprising an ultrasound positioning epidural puncture needle assembly and a puncture sensor assembly, wherein the ultrasound positioning epidural puncture needle assembly comprises a puncture needle seat. The ultrasound-guided pressure monitoring epidural anesthesia positioning device can accurately determine the position of a needle tip, effectively avoid complications such as rupture of the spinal cord, blood vessel injury and nerve injury caused by blind puncture, significantly improve anesthesia safety, and clearly display anatomical structures such as ligaments and the spinal cord through ultrasound guidance. The ultrasound-guided pressure monitoring epidural anesthesia positioning device can significantly improve the puncture success rate for obese, patients with spinal deformity and old patients who are difficult to puncture in a traditional way. Meanwhile, the puncture pressure sensor can continuously monitor and display the pressure change curve in the puncture process, provide objective and quantitative judgment basis, and reduce the dependence on the subjective experience of an operator.

The application discloses a spinal cord hemisection device and a hemisection method for manufacturing an animal spinal cord injury model. The spinal cord hemisection device comprises a spinal cord hemisection device main body and a master control center. The master control center is arranged outside the spinal cord hemisection device main body and is used for controlling the action of the spinal cord hemisection device main body. The spinal cord hemisection device main body comprises a fixing frame, a hemisection driving mechanism, a spinal cord fixing structure and a cutting assembly. The hemisection driving mechanism is arranged on the fixing frame. The cutting assembly is installed on the hemisection driving mechanism in a lifting manner. After the fixing frame is arranged above a non-human primate to be modeled and a surgical incision of a dura mater is manually opened, the spinal cord fixing structure penetrates into the gap between the spinal cord and the dura mater, surrounds the outer periphery of the spinal cord, the hemisection driving mechanism is located above the incision and drives the cutting assembly to act, and the spinal cord fixing structure performs spinal cord hemisection. The application does not damage too much dura mater and is convenient for postoperative maintenance.