10 results about "Dibromopropane" patented technology

The application belongs to the technical field of oil and gas field development, and particularly relates to a temperature-resistant and salt-resistant foaming agent for drilling and a synthesis method thereof. The synthesis method is as follows: diphenylamine-4-sodium sulfonate, isopropyl alcohol and 1,3-dibromopropane are added into a four-necked flask, stirred, heated and refluxed to obtain a mixed solution; 90-95wt% of isopropyl alcohol in the mixed solution is distilled off under reduced pressure, distilled water is added, and the whole is transferred into a separatory funnel, fully shaken, separated, and a small amount of oil phase is discarded; the pH is adjusted to 2-3, a precipitate is separated out, suction filtration is performed, and an intermediate is obtained; the intermediate is transferred into a four-necked flask with isopropyl alcohol, sodium bromoethyl sulfonate is added, the pH is adjusted to 7-8, and the product solution is obtained by heating and refluxing; the product is obtained by vacuum distillation, recrystallization and drying. The foaming agent for drilling has the advantages of good temperature resistance, salt resistance and salinity resistance.

This invention discloses a magnetically supported thioether-chelated nitrogen heterocyclic carbene palladium complex MNPs-NHC-Pd, its preparation method, and its applications. Using an amino alcohol as a starting material, an imidazole derivative containing a hydroxyl group on the N-substituent is obtained through a condensation and ring-closing reaction. This derivative is then subjected to substitution reactions with thionyl chloride and cyclohexanethiol sequentially to obtain an imidazole derivative containing a thioether on the N-substituent. This derivative is then reacted with 1,3-dibromopropane to obtain an N-bromopropyl-N'-cyclohexane thioether-substituted imidazole bromium salt. This salt is then reacted with Pd(OAc)₂ or PdCl₂ via a direct metallization reaction to obtain the N-bromopropyl-substituted thioether-chelated nitrogen heterocyclic carbene palladium complex NHC-Pd. The NHC-Pd complex is then reacted with amino-functionalized magnetic nanoparticles (MNPs-NH₂) to prepare the magnetically supported thioether-chelated nitrogen heterocyclic carbene palladium complex MNPs-NHC-Pd. It not only possesses the activity of homogeneous nitrogen heterocyclic carbene palladium catalysts, but also has a simple synthesis method, high yield, and is easy to separate and reuse in catalytic C-C bonding reactions, showing good application prospects in the field of catalysis.

The invention provides a preparation method of Aciramidis, and relates to the technical field of organic synthesis. The method comprises the following steps: mixing acetylacetone, 1, 3-dibromopropane, a phase transfer catalyst, alkali and an organic solvent, and carrying out nucleophilic substitution reaction; mixing the compound as shown in the formula I, hydrazine hydrate and an organic solvent for condensation reaction; mixing the compound as shown in the formula J, 4-nitro-3-hydroxybenzoic acid, acid and an organic solvent, and carrying out ring-opening reaction; and mixing the obtained compound shown in the formula L, a fluorinating reagent, a phase transfer catalyst and an organic solvent, and carrying out aromatic nucleophilic substitution reaction to obtain Aoramidis. The cheap reagent 4-nitro-3-hydroxybenzoic acid is used, so that the production cost can be greatly reduced; through the construction of a four-membered ring, the reaction steps are optimized, and the Aoramidis can be prepared through the four-step reaction. The method is low in cost, few in synthesis steps and more beneficial to industrial production.

This invention discloses a haloalkane dehalogenase HLD-1405, its encoding gene, and its applications, belonging to the field of biotechnology. The amino acid sequence of this haloalkane dehalogenase HLD-1405 is shown in SEQ ID NO.2, and its encoding gene is shown in SEQ ID NO.1. This haloalkane dehalogenase HLD-1405 exhibits high catalytic activity towards 1,3-dibromopropane, with optimal operating conditions of 40℃ / pH 9.0, and retains 100% activity in 20% methanol. This haloalkane dehalogenase HLD-1405 can efficiently degrade short-chain haloalkanes and also has the ability to degrade pollutants such as DDT and hexachlorocyclohexane (HCH), showing great application potential in the treatment of stubborn pollutants and suitable for environmental bioremediation and industrial catalysis.

This invention relates to the application and method of a fluorescent ionic liquid in the detection of nitrophenol isomers. The fluorescent ionic liquid is (poly)1,3-di(N-methylimidazolyl)propane-1,4-naphthalenedicarboxylate, and the structure of the compound is shown in the following formula. The preparation method is as follows: First, 30 mL of NaOH solution (3 mol / L) and 9.47 g of 1,4-naphthalenedicarboxylate are added sequentially to a single-necked flask, and the mixture is refluxed at 30 °C for 24 h to obtain a clear brown solution, which is a sodium 1,4-naphthalenedicarboxylate solution. Next, 8 mL of 1,3-dibromopropane, 12 mL of N-methylimidazolium, and 50 mL of acetone are added sequentially to a three-necked flask. The mixture is stirred and refluxed at 45 °C for 20 h, washed three times with 50 mL of acetone each time, and filtered to obtain a white solid powder. Finally, the prepared sodium 1,4-naphthalenedicarboxylate solution and 8.3 g of the white solid product obtained in step two are added sequentially to a single-necked flask, and the mixture is stirred and reacted at 50 °C for 24 h. The prepared solution was rotary evaporated, dried, diluted with anhydrous ethanol, filtered, and dried again to obtain the target product (poly)1,3-di(N-methylimidazolyl)propane 1,4-naphthalenedicarboxylate. This invention is simple to operate and has high fluorescence intensity and sensitivity, making it suitable for fluorescence analysis and identification of nitrophenol isomers.

The invention discloses a blue light CsPbBr3 superlattice and a preparation method and application thereof, and belongs to the technical field of perovskite material preparation. The preparation method comprises the following steps: in a ketone solvent, reacting 4-hydroxytetraphenylethylene, 1, 3-dibromopropane and potassium carbonate to obtain (2-(4-(3-bromopropoxy) phenyl) ethylene-1, 1, 2-triyl) tribenzene; in an alcohol solvent, reacting the product with trimethylamine to obtain N, N-dimethyl-N-(3-(4-(1, 2, 2-triphenyl vinyl) phenoxy) propyl) methyl ammonium; dissolving the ligand in a halogenated hydrocarbon organic solution to obtain a ligand solution; and sequentially adding the ligand solution and the cesium oleate solution into the lead bromide solution, and carrying out ion exchange reaction at normal temperature to obtain the blue-light CsPbBr3 superlattice. The tetraphenyl ethylene quaternary ammonium salt molecules are introduced, so that the stability and highly ordered self-assembly of the nanosheet are improved.

The invention belongs to the technical field of organic synthesis, and particularly relates to a preparation method of absolute chiral 2-hydroxyhexahydro-1H-pyridine cyclo-7a-formic acid. The preparation method comprises the following steps: reacting 1-Boc-4-hydroxypyrrolidine-2-formic acid with benzyl bromide to obtain a first intermediate product; reacting the first intermediate product with 1, 3-dibromopropane to obtain a second intermediate product; reacting the second intermediate product with trifluoroacetic acid to obtain a third intermediate product; adjusting the pH value of the aqueous solution of the third intermediate product to be greater than or equal to 11 to obtain a fourth intermediate product; reacting the fourth intermediate product with a chiral agent to obtain a fifth intermediate product; and carrying out a reaction on the fifth intermediate product under a hydrogen condition to obtain the absolute chiral 2-hydroxyhexahydro-1H-pyridine cyclo-7a-formic acid. The absolutely chiral 2-hydroxyhexahydro-1H-pyridine cyclo-7a-formic acid product is prepared by reasonably optimizing the reaction process and adopting the simple reaction process, and is suitable for industrial application.

The application discloses a preparation method and application of a branched polyarylide ion exchange membrane, and comprises the following steps: preparing a branched polyarylide high polymer by using p-terphenyl, diphenylethane, triphenylmethane and indigo; preparing 6-bromoalkyl-1-methylpiperidine monomers by using 1,3-dibromopropane and N-methylpiperidine; after reaction of the branched polyarylide high polymer, the 6-bromoalkyl-1-methylpiperidine monomers and K2CO3, pouring into ethyl acetate, filtering and drying, piperidine functionalized branched polyarylide high polymer is obtained; after dissolving the piperidine functionalized high polymer in N-methylpyrrolidone, casting on a glass plate, drying into a film, soaking in a KOH solution, a branched polyarylide ion exchange membrane is obtained. − The branched polyarylide ion exchange membrane has excellent OH conductivity, and meets the application requirement of anion exchange membrane electrolysis water.

This invention provides a method for preparing high-purity piminodin, relating to the field of piminodin preparation. The method includes: a first nucleophilic substitution of 1,3-dibromopropane and aniline, followed by deprotection treatment of 1-benzyl-4-cyano-4-phenylpiperidine hydrochloride, hydrolysis, esterification, and a second nucleophilic substitution to obtain crude piminodin, which is then purified to obtain piminodin with a purity greater than 99.9%. This invention uses readily available commercial raw materials and shortens the synthetic route compared to existing methods, significantly improving synthetic efficiency. In the intermediate synthesis process, each reaction step has only one reaction site. In the deprotection process, palladium on carbon is used as a catalyst to improve the reaction yield. Simple treatment allows for direct vacuum concentration, overcoming the low yield problem of existing deprotection steps. The purification process removes most impurities through natural volatilization of n-hexane, and after two recrystallizations, the purity of the piminodin product is greater than 99.6%, with a single impurity content of less than 0.2%.

The application discloses nano-antibacterial polyester masterbatch and an extrusion preparation method thereof, and belongs to the technical field of polyester masterbatch preparation. The nano-antibacterial polyester masterbatch is composed of the following components in parts by weight: 50-70 parts of polybutylene terephthalate, 10-22 parts of a nano-antibacterial agent, 5-10 parts of a composite anti-yellowing agent, 0.5-1.2 parts of a dispersing agent, 1-3 parts of a lubricant, 6-9 parts of a filler and 0.3-0.6 parts of a plasticizer, wherein the nano-antibacterial agent is prepared from o-phenylenediamine, 2-thiophene formaldehyde, bromine propargyl, 4-fluorochlorobenzyl and sodium azide, and the composite anti-yellowing agent is prepared from 4-hydroxyacetophenone, benzaldehyde, 1,3-dibromopropane, 4-[(methylamino)methyl]piperidine-1-carboxylic acid tert-butyl ester and p-methoxybenzenesulfonyl chloride. The polyester masterbatch prepared by the method has excellent antibacterial performance and anti-aging performance.