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7 results about "Balanced salt solution" patented technology

A balanced salt solution (BSS) is a solution made to a physiological pH and isotonic salt concentration. Solutions most commonly include sodium, potassium, calcium, magnesium, and chloride. Balanced salt solutions are used for washing tissues and cells and are usually combined with other agents to treat the tissues and cells. They provide the cells with water and inorganic ions, while maintaining a physiological pH and osmotic pressure.

Phacoemulsification aspiration sleeve for intraocular and extraocular penetration and perfusion confirmation of glaucoma tube surgery

ActiveKR102991524B1ConjunctivaAqueous humor
The present invention relates to an ophthalmic ultrasonic emulsification sleeve for confirming intraocular and extraocular penetration and perfusion, which allows determining whether aqueous humor communication between the inside and outside of the eye is smooth through a microtube implanted in the eye during glaucoma tube surgery. The sleeve is characterized by having a rigid branch tube made of a material harder than a sleeve made of a soft material, provided in a perfusion port that allows the injection of a balance salt solution into the eye, and with the branch tube connected to the perfusion port, the tip of the branch tube protrudes further than the tip of the Paco tip, and the end of the microtube inside the eye is connected to the tip of the branch tube, so that the establishment of aqueous humor communication of the microtube can be quickly and accurately and sensorially confirmed based on the pattern of pressure change in the conjunctival area and surrounding blood flow change that occurs when the balance salt solution leaks out of the eye.
Owner:THE CATHOLIC UNIV OF KOREA IND ACADEMIC COOP FOUND

A detection kit and identification method for CTCs based on SCLC molecular typing using microfluidic chips and multiplex immunofluorescence probe technology.

This invention discloses a detection kit and identification method for CTCs based on SCLC molecular typing using microfluidic chips and multiplex immunofluorescence probe technology. The kit includes a microfluidic chip, a biotin-labeled trapping agent, a balanced salt solution, a tissue cell fixation solution, a specific hybridization blocking solution, an active nuclear staining solution, and a diluent. It also includes a detection agent composed of key subtype markers of SCLC labeled with different fluorescein groups, SCLC-related marker detection antibodies, and leukocyte auxiliary identification markers, or a detection agent composed of key subtype markers of SCLC labeled with different fluorescein groups and leukocyte auxiliary identification markers. This application enables non-invasive, early, and sensitive detection and analysis of the expression of four immunomarkers involved in CTCs in the peripheral blood of patients: ASCL1, NEUROD1, POU2F3, and YAP1. It is suitable for early tumor screening and can also be used for pan-cancer immunotherapy guidance, immunotherapy efficacy monitoring, and prognostic assessment.
Owner:HANGZHOU WATSON BIOTECH INC

Anterior chamber maintainer (ACM)

PendingUS20250367029A1Eye surgeryMedical devicesParacentesisSaline solutions
An anterior chamber maintainer (ACM), which is to be utilized in connection with maintaining physiological intraocular pressure during intraocular surgery, is disclosed and comprises an axially elongated tubular member which is adapted to be fluidically connected at a first end to a supply of balanced salt solution (BSS) for introduction into the anterior chamber of an eye so as to maintain adequate intraocular pressure while performing any intraocular surgery. A second opposite end of the anterior chamber maintainer (ACM) is provided with a sharply pointed end for insertion through a paracentesis incision formed within the limbus region of the eye, and a non-deformable, incompressible, tapered, annular bulbous portion is interposed between the first and second ends such that as the second end passes through the paracentesis incision, the non-deformable, incompressible, tapered, annular bulbous portion will cause the paracentesis incision to deform or expand radially outwardly, and after passing through the paracentesis incision, the non-deformable, incompressible, annular bulbous portion will trap the anterior chamber maintainer (ACM) within the anterior chamber of the eye.
Owner:WHITSETT JEFFREY

Compatibility method of retinal pigment epithelial cell cryopreservation preparation

PendingCN120860062ASenses disorderDead animal preservationAmino Acid InjectionCryopreservation
The invention relates to a compatibility method of a retinal pigment epithelial cell cryopreservation preparation, which comprises the steps of dilution, balancing, washing and compatibility: 1) a dilution step: preparing a diluted solution which comprises a balanced salt solution (for perfusion), preferably, the diluted solution further comprises a compound amino acid injection; 2) a balancing step: resuscitating cells in the RPE cell cryopreservation preparation, then mixing the cells with the prepared diluted solution, and standing for balancing; (3) washing: centrifuging the solution, absorbing and discarding the supernate, adding a balanced salt solution (for perfusion), resuspending the cells, centrifuging, and absorbing and discarding the supernate; and 4) a compatibility step: adding a balanced salt solution (for perfusion) into the cell precipitate, and adjusting the cell to a required density according to a living cell density result.
Owner:BEIJING ZEPHYRM BIOTECHNOLOGY CO LTD

Systems for real-time laser power monitoring

The present disclosure generally relates to systems and methods for laser power measurement, and more particularly, systems and methods for laser power measurement in a sterile operating environment. In certain embodiments described herein, power measurement is performed utilizing two laser sources: 1) a first laser source configured to generate a first laser beam (treatment laser); and 2) a second laser source configured to generate a second laser beam (test laser). The first laser beam generates a bubble in a test material (e.g., water, saline, balanced salt solution, gel, etc.) and the second laser beam is reflected back with the reflected portion of the second laser beam being measured to determine a lifetime of the bubble and correlate the lifetime measurement with a power measurement based on a correlation curve.
Owner:ALCON INC

A system for real-time laser power monitoring

[0001] The present disclosure relates generally to systems and methods for laser power measurement, and more particularly, to systems and methods for laser power measurement in a sterile working environment. In certain embodiments described herein, power measurements are made utilizing two laser sources: 1) a first laser source configured to generate a first laser beam (a treatment laser), and 2) a second laser source configured to generate a second laser beam (a test laser). The first laser beam generates gas bubbles in a test material (e.g., water, saline, balanced salt solution, gel, etc.), and the second laser beam is reflected back, and the reflected portion of the second laser beam is measured to determine the bubble lifetime, and the lifetime measurements are correlated with power measurements based on a correlation curve.
Owner:ALCON INC

Ocular insert for use in the treatment of dry eye

A tear-fluid insoluble, ocular insert adapted for insertion into the eye of a subject, which is a mammal, for the sustained release of an agent selected from a therapeutic agent, a balanced salt solution, and a mixture thereof, wherein the insert comprises a bacterial cellulose hydrogel and an aqueous solution comprising the therapeutic agent and / or balanced saline solution.
Owner:CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) +1