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Gastrointestinal tract oral CT (Computed Tomography) contrast agent

A contrast agent, gastrointestinal technology, applied in the direction of X-ray contrast agent preparation, etc., can solve the problems of reducing the efficiency of radiologists in examining gastrointestinal diseases, increasing the economic burden of patients, and short residence time, reducing the intake of a large amount of water and The problem of contrast media, the effect of improving diagnostic efficiency and reducing economic burden

Pending Publication Date: 2022-04-08
福建宸润生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Diatrizoate or ioversol, which is commonly used clinically, is mixed with drinking water to assist gastrointestinal CT contrast, because it takes a lot of time for patients to undergo CT examinations and wait for examinations, while diatrizoate or ioversol Ioversol mixed with drinking water is used to assist gastrointestinal contrast in the gastrointestinal tract for a short period of time, and as time goes by, its CT value decreases significantly, which will reduce the efficiency of radiologists in the examination of gastrointestinal diseases
In order to ensure the accuracy of the disease examination, the patient can only ingest a large amount of drinking water and contrast agent again, which not only increases the financial burden for the patient, but also makes the patient's body in an uncomfortable state

Method used

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  • Gastrointestinal tract oral CT (Computed Tomography) contrast agent
  • Gastrointestinal tract oral CT (Computed Tomography) contrast agent
  • Gastrointestinal tract oral CT (Computed Tomography) contrast agent

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] A gastrointestinal oral CT contrast agent, comprising 1% food grade liquid paraffin, 1% soybean salad oil, 0.6% sodium carboxymethyl cellulose, 0.15% xylitol, 0.15% potassium sorbate, and ioversol Or iohexol 0.5%, the rest is purified water.

Embodiment 2

[0018] A gastrointestinal oral CT contrast agent, comprising 0.5% food grade liquid paraffin, 0.5% soybean salad oil, 0.5% sodium carboxymethyl cellulose, 0.1% xylitol, 0.1% potassium sorbate, and ioversol Or iohexol 1%, the rest is purified water.

Embodiment 3

[0020] A gastrointestinal oral CT contrast agent, comprising 1.5% food grade liquid paraffin, 1.5% soybean salad oil, 1% carboxymethyl cellulose sodium, 0.3% xylitol, 0.15% potassium sorbate, and ioversol by weight 0.75% or iohexol%, and the rest is purified water.

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PUM

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Abstract

The invention discloses an oral CT (Computed Tomography) contrast agent for gastrointestinal tracts. The oral CT contrast agent comprises the following components in percentage by mass: 0.5-1.5% of edible liquid paraffin, 0.5-1.5% of soybean salad oil, 0.5-1% of sodium carboxymethyl cellulose, 0.1-0.3% of a food additive, 0.1-0.2% of a preservative, 0.5-1% of ioversol or iohexol and the balance of purified water. The gastrointestinal tract contrast performance can be remarkably improved, the contrast agent CT imaging time can be prolonged, the diagnosis efficiency of doctors is effectively improved, the problem that a large amount of water and contrast agents are taken again is reduced, the economic burden of patients is reduced, and the situation that the bodies of the patients are uncomfortable is prevented.

Description

technical field [0001] The invention belongs to the technical field of CT imaging examination, and in particular relates to a CT contrast agent taken orally in the gastrointestinal tract. Background technique [0002] In the X-ray examination of the human abdomen, there are many internal organs and the density of the tissues is roughly similar. It is necessary to introduce a CT contrast agent that is harmless to the human body to improve the contrast of the gastrointestinal tract or lesions in order to achieve ideal diagnosis and inspection results. [0003] Diatrizoate or ioversol, which is commonly used clinically, is mixed with drinking water to assist gastrointestinal CT contrast, because it takes a lot of time for patients to undergo CT examinations and wait for examinations, while diatrizoate or ioversol Ioversol mixed with drinking water is used to assist gastrointestinal contrast in the gastrointestinal tract for a short period of time, and as time goes by, its CT va...

Claims

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Application Information

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IPC IPC(8): A61K49/04
Inventor 张达刘小龙密夫山林展杨英祥陈三妹王昌华
Owner 福建宸润生物科技有限公司
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