227results about How to "Synthetic raw materials are readily available" patented technology

The invention discloses a halogen-free high-efficiency flame retardant composition and a preparation method thereof. The halogen-free high-efficiency flame retardant composition is prepared from the following components in percentage by mass: 10-80% of phenyl melamine carboxyethyl phenyl phosphinic acid condensation compound, 15-70% of melamine and / or derivative thereof and 5-20% of organic phosphate. The halogen-free flame retardant composition can be used for flame retarding of various polyolefin, nylon, polyurethane, polyester and other synthetic materials and textiles, and is particularly suitable for polyester and nylon engineering plastic; and by the addition of 12wt% of the flame retardant composition to polybutylene terephthalate (PBT) resin, the flame-retarding level can reach UL 94 V-0 (1.6 mm). The flame retardant composition has the characteristics of high flame retarding efficiency, good fluidity, no precipitation and the like, and can meet the use requirements of flame-retardant resin for electric appliance shells and supports, electronic and electric device connectors and the like.

The invention discloses several non-peripherial substituted phthalocyanine metal complexes and making method, which introduces functional group into position a (position 1(4), 8(11), 15(18) and 22(25)) of phthalocyanine complex.

The present invention provides several application of non-peripheral substituted phthalocyanine metal coordination compound. The invented phthalocyanine metal coordination compound has the application for preparing photosensitive medicine preparation which can be used in photodynamic therapy or photodynamic diagnosis, and has the application for preparing photosensitizer which can be used in photodynamic purification or disinfection. Besides, it can be used as fluorescence probe or can be used for determining protein content.

The invention discloses a preparation method of a metal organic framework material and application of the metal organic framework material in a cyclohexyl hydroperoxide decomposition reaction. Transition metal salt and terephthalic acid or a derivative thereof are subjected to a hydrothermal synthesis reaction in a sodium acetate solution to obtain the metal organic framework material, then the metal organic framework material serving as a catalyst is added into industrial cyclohexane uncatalysed oxidation liquid, the temperature is controlled to be 50-150 DEG C, the time is controlled to be 0.1-5 h, cyclohexyl hydroperoxide decomposition is carried out to obtain hexamethylene and cyclohexanone, the conversion rate of cyclohexyl hydroperoxide is larger than 95%, and the selectivity of alcohol ketone reaches up to 100%; the activity of the repeatedly-recycled catalyst is kept unchanged basically. Compared with other catalysts containing metal active components, the catalyst is high in catalytic efficiency, recyclable and stable in reusability; when the catalyst is applied to the cyclohexyl hydroperoxide decomposition reaction, the decomposition process is conducted under the alkali-free condition, the catalytic efficiency is very high, and pollution caused by waste alkali liquor to the environment is avoided.

The invention discloses amphiphilic block copolymer connected through molecular glue and a synthesis method and application of the copolymer, a hydrophilic compound and a hydrophobic compound for synthesizing the copolymer, and preparation methods of the compounds. The copolymer M has a structural formula shown in the specifications. The amphiphilic block copolymer M is prepared by mixing the hydrophilic compound, the hydrophobic compound and an oxidant in a halogenated hydrocarbon solvent. The copolymer M can be used as a medicine transport carrier, and a medicine is poorly soluble in water. Raw materials for synthesizing the compounds are simple and readily available, the synthesis process is the conventional reaction process, reaction conditions are mild, and the compounds can be massively prepared; and a micelle formed by self-assembling the block copolymer can be used for the medicine transport carrier.

The invention discloses a phthalocyanine metal complex as well as a preparation method and an application of the phthalocyanine metal complex. 3-[2,4,6-tri(dimethylamino methyl)-phenoxyl] phthalonitrile is prepared by using 2-phthalonitrile nitryl and 2,4,6-tri(dimethylamino methyl)-phenol as reactants, and further, the phthalocyanine metal complex substituted with amido or amido alpha bit is prepared. The phthalocyanine metal complex has the characteristics of high photosensitive activity and high water solubility; the phthalocyanine metal complex exists in water in a monomer mode, so that the photodynamic activity is facilitated in the water; the phthalocyanine metal complex is subjected to absorption spectroscopic redshift and shifted to a near-infrared area where is beneficial for penetrating through human tissues. The phthalocyanine metal complex is specially high in photodynamic antifungal activity and can be used for preparing photosensitizers or photodynamic medicines or photosensitive medicaments.

The invention provides a ring amidino-polymer flocculant and a preparation method thereof. The flocculant has the characteristics of large limiting viscosity, high charge density, good water solubility and the like, and is polymerized by acrylamide functional monomer and acrylonitrile through radicals. In the structural formula of the flocculant, degree of polymerization m is between 100 and 6,000, and degree of polymerization n is between 100 and 1,000; X is -Cl or -HSO4; and Y is one of -CN, -NH2, -CONH2, -NHCHO and -COOH substituent groups.

The invention provides a non-hydrolytic sol-gel method for preparing high-dispersity nano alumina, which comprises the following steps of: preparing a precursor by mixing an aluminum salt with an alcoholic solvent, heat-treating the prepared precursor by using a low-temperature non-aqueous solvent, washing the product with ethanol, centrifuging and then drying to obtain the powder body of the nano alumina with high dispersity. The nano alumina has small particle sizes which are distributed evenly, and can be stably dispersed in water. In the whole producing process, the raw materials are easy to get, the operation is simple, no minute and complicated sample after-treatment processes exist, the reaction yield reaches up to 98%, the industrial amplification factor is small, and thus the industrial production of the high-dispersity nano alumina can be realized.

The invention discloses a method of producing medium and mid-high olefines, such as C8, C12, C16 and C20, etc. with ionic liquid as catalyst to catalyze butylene to carry out butylene oligomerization. The method adopts the butylene as raw material; cation of the ionic liquid catalyst comes from hydrohalide of amine with alkyl, and anion of the ionic liquid catalyst is produced by a metallic compound that has one or two metals. In the technique of the invention, volume ratio of catalyst to butylene is low; conversion efficiency of butylene is high; selectivity of oligomerized product is high; distribution of oligomerized product is improved, and the invention has good social and economic benefits.

The invention relates to the field of pharmacy, and discloses a benzoic acid alogliptin composition troche and a preparation method thereof. The effective components of the benzoic acid alogliptin composition troche comprise benzoic acid alogliptin, mannitol, microcrystalline cellulose, croscarmellose sodium, magnesium stearate and 5% hydroxy propyl cellulose aqueous liquor. The synthetic materials are easy to obtain and low in cost. The troche is quick in disintegration speed, high in dissolution rate, good in stability, accurate in dosage and convenient to take and carry. The benzoic acid alogliptin composition troche is simple in step, short in production period, low in production cost and suitable for industrialized application, and the technical process is easy to control,.

The invention belongs to the technical field of drug preparation and specifically relates to a sitagliptin phosphate tablet and a preparation method thereof. The sitagliptin phosphate tablet comprises the following raw materials in parts by weight: 30 parts of sitagliptin phosphate, 55-70 parts of filler, 0-5 parts of adhesive, 1.5-3.0 parts of disintegrating agent and 1.5-5.0 parts of lubricating agent; the filler is selected from one or more of microcrystalline cellulose, sugar and inorganic salt; the adhesive is selected from one or more of hydroxypropyl methylcellulose, hydroxypropylcellulose, povidone K30 and starch; the disintegrating agent is selected from one or more of crosslinking sodium carboxymethylcellulose, sodium carboxymethyl starch and polyvinylpolypyrrolidone. Compared with the prior art, the sitagliptin phosphate tablet provided by the invention has the technical effects of easily acquired compound raw materials, high disintegration speed, high dissolution rate, high stability, simple steps of preparation method, easily controlled technological process, short production period, low production cost and suitability for industrialized application.

The invention discloses a preparation method of a multi-nuclear-shell hollow type catalyst nickel-nickel silicate-SiO2 based on methane reforming. The preparation method is characterized by includingthe following steps: (1) preparing silicon dioxide nanoparticles; (2) preparing the silicon dioxide nanoparticles with the particle size of 500 nanometers to 1 micrometer into a solution with the concentration of 1-10g / L, adding alkali liquor to adjust the pH to 8-13, adding nickel precursors with the concentration of 1-10g / L, and synthesizing into hollow nickel silicate spheres at the temperatureof 50-220 DEG C; (3) dispersing the hollow nickel silicate spheres into mixed liquor of surfactants and water, adding the alkali liquor after stirring, adjusting the pH to 10-14, and adding 10mL of tetraethoxysilane for room-temperature reaction to obtain nickel silicate-SiO2 nuclear shell hollow spheres; (4) reducing the nickel silicate-SiO2 nuclear shell hollow spheres under a hydrogen atmosphere with the temperature of 300-800 DEG C to obtain the high-dispersion nickel-nickel silicate-SiO2 multi-nuclear-shell hollow type catalyst. The prepared catalyst has the advantages of high sinteringresistance, high carbon deposition resistance, high-temperature stability and high specific surface area.

The invention relates to an ethylenediamine bicyclo-tetra methylene melamine phosphonate compound and a preparation method thereof, in particular to a novel ethylenediamine bicyclo-tetra methylene melamine phosphonate for polymer flame retardance and the preparation method thereof. The compound synthesized by a two-step method has the characteristics of high phosphor / nitrogen content, high thermal stability, good hydrolysis resistance and the like, wherein due to triazine ring and phosphor-oxygen-nitrogen six-membered heterocyclic ring in the molecular structure, the thermal stability of the compound is greatly improved, the decomposition temperature of the compound is higher than 280 DEG C; and the charing property and flame retardance of a flame retarding system can be greatly improved due to the triazine ring structure in the molecular structure, and the excellent synergetic flame retarding effect of organic phosphor and six-membered heterocyclic ring can be represented. The compound synthesized by the invention can be widely applied to flame retardance of various synthetic materials and textiles such as polyolefin, polyurethane, nylon and polyester; raw materials for synthesizing the compound are easy to obtain, the production process is simple, and is suitable for industrial production and application.

The invention relates to inorganic nano-material preparing, particularly to a preparation method for photosensitive and amphiphilic polyurethane-stabilized nano-zinc oxide, wherein a new photosensitive and amphiphilic polyurethane is adopted to carry out coating, an inverse emulsion technology is adopted to prepare the nano-zinc oxide, such that the photosensitive and amphiphilic polyurethane-stabilized nano-zinc oxide is formed. The novel nano-zinc oxide synthesized through the method provided by the present invention has a particle size of 20-800 nm, can be regulated through simply controlling reaction conditions (such as reactant concentrations, ultrasonic emulsification power and the like), and has good dispersity and good dispersion stability in an organic solvent system. The synthesis method for the photosensitive and amphiphilic polyurethane prepolymer has characteristics of simpleness, controllable process, easy availability of the raw materials, non toxicity and harm, and easy industrial production. The prepared nano-ZnO can be adopted as a functional nano-filler in various polymer systems, such that characteristics of anti-ultraviolet property, mechanical property and the like of the polymer can be improved.

The invention discloses application of non-surrounding displaced phthalocyanine zinc in preparing sonosensitizer, in particular discloses the non-surrounding displaced phthalocyanine zinc used as sonosensitizer in preparing sonodynamic therapy medicines. The non-surrounding displaced phthalocyanine zinc provided by the invention has a better biological compatibility, better biological selectivityand higher stability; and the preparation is simple, the operation is easy, synthetic raw materials are easy to obtain, and industrialization is easy to realize.

The invention relates to a chiral nitrogen-sulfur bidentate ligand and a synthesis method and an application thereof. The chiral nitrogen-sulfur bidentate ligand is obtained by esterifying carboxylic acid firstly and then carrying out a reaction with chiral sulfinyl amine; the ligand is combined with a transition metal palladium, symmetrical allyl acetate is used as a substrate, dimethyl malonate and dimethyl fluoromalonate are used as nucleophilic reagents, and a chiral carbon-carbon bond is successfully constructed. Compared with the prior art, the chiral nitrogen-sulfur bidentate ligand has easily obtained synthetic raw materials, and the synthetic method is simple; the prepared chiral nitrogen-sulfur bidentate ligand is N-(sulphinyl)picolinamide with optical activity is applied in construction of the chiral carbon-carbon bond catalyzed by the transition metal palladium, the reaction conditions are mild, the operation is simple, in addition, the reaction yield is also better and is generally 78%-99%, and the enantioselectivity is high and has the highest value of 93%.

The invention belongs to the technical field of a porous frame material and relates to a metallic organic frame material for separating CO2 and a preparation method thereof. The method comprises the following steps: uniformly mixing 0.2mmol cupric salt, 0.1mmol organic ligand, 5mL dimethyl sulfoxide, 2mL ethyl alcohol and 0.02-0.08mL hydroiodic acid and then filling into a glass bottle with a cover; crystalizing for 1 day at 90 DEG C, thereby acquiring a massive green crystal with excellent crystallinity; and using alcohol for cleaning the acquired massive green crystal and drying under room temperature, thereby acquiring an inorganic-organic hybrid porous metallic organic frame crystal compound. The prepared porous metallic organic frame crystal compound is a novel functional material forseparating CO2 mixed gas; the separating effect is excellent; the compounding materials are simple and feasible; the method is simple; the operation is convenient; and the repeatability is high.

The invention discloses a phthalocyanine-hydrotalcite complex and a preparation method and application thereof, and belongs to the field of inorganic-organic composite functional materials and preparation of photodynamic drugs. The complex consists of hydrotalcite and phthalocyanine, wherein the hydrotalcite electrostatically interacts with phthalocyanine; the phthalocyanine is insercalated between hydrotalcite layers, or is adsorbed to the surface of hydrotalcite; the weight percent of phthalocyanine in the complex is 0.01 to 50. The complex forms stable nanoparticles in a physiological solution, and is high in biocompatibility and photostability; the fluorescent performance and photodynamic activity of the complex are sensitive to the pH value of a system, so that the complex can be used as a targeted photosensitizer responsive to a tumor slightly-acid environment.

The present invention uses racemic valine (DL-Val) as raw material, uses inorganic acid as solvent, uses dextral dibenzoyl tartaric acid (D-DBTA) and levo-dibenoyl tartaric acid (L-DBTA0 as resolution agent according to the ratio of 1:0.5-1.2 in dilute inorganic solution, stirring for 0.5-2.0 hr. at 60-100 deg.C, then progressively cooling to room temp., filtering out crystal salt, using alkali to neutralize said crystal salt and mother liquor respectively in water and ethyl alcohol so as to respectively obtain the invented dextral valine (D-Val) and levo-valine (L-Val).

The invention provides an easily-modified near-infrared region II organic small molecule dye and a synthetic method and application of the easily-modified near-infrared region II organic small molecule dye. The near-infrared region II fluorescent dye belongs to polymethenyl pyran or polymethenyl thiapyran salt organic small molecules, and is prepared by a condensation reaction of polymethenyl aniline salt with pyran or thiopyran salt. The synthetic raw materials are easy to obtain, the cost is low, the preparation process is simple, the yield is high, and large-amount synthesis can be achieved. The purpose of adjusting the fluorescence emission spectrum is achieved by changing an intramolecular polymethenyl chain and hetero atom species. The small molecule dye has the maximum emission wavelength range of 1000-1200 nm, and is high in fluorescence quantum yield, good in light stability and quite applicable to living imaging. The small molecule dye can be linked to groups with specific functions by click chemistry for a variety of bioimaging application. Near-infrared region II fluorescent living imaging achieves low background noise, strong fluorescence signal and high signal-to-noise ratio.

The invention discloses a method for preparing multi-nuclear-shell hollow nickel-nickel silicate-CeO2 through methane reforming. The method includes the steps of (1) preparing silicon dioxide nanoparticles; (2) adding nickel precursors into the silicon dioxide nanoparticles, and preparing hollow nickel silicate spheres at the temperature of 50-220oC; (3) dispersing the hollow nickel silicate spheres into mixed liquor of ethyl alcohol and water, adding CeO2 precursors and precipitators, and performing reaction at the temperature of 40-150oC to obtain nickel silicate-CeO2 nuclear shell hollow nanospheres; (4) reducing the nickel silicate-CeO2 nuclear shell hollow nanospheres to obtain the high-dispersion nickel-nickel silicate-CeO2 multi-nuclear-shell hollow catalyst. The prepared multi-nuclear-shell hollow nickel-nickel silicate-CeO2 catalyst has the advantages of high sintering resistance on nickel and CeO2, hyperoxia hole concentration, high carbon deposition resistance, high nickel dispersity, high CeO2 dispersity and the like, and displays high catalytic activity and carbon deposition resistance when being applied to catalytic reaction based on low-temperature methane reforming.

The invention discloses 2-phenoxyl tetrahydrofuran (tetrahydropyrane) derivatives and the application thereof in synthesis of penoxsulam, and belongs to the field of pesticide synthesis. A new intermediate of a penoxsulam pesticide is synthesized by the derivatives of the design of the invention. A high-toxicity raw material is not required to be used in the preparation of the intermediate; a product is convenient to purify and high in yield; a synthesizing process is environment-friendly; the synthesis cost is low. The penoxsulam pesticide can be prepared conveniently by utilizing the intermediate; the intermediate has a good application prospect. The series of derivatives are easy and convenient to synthesize; compared with the reported penoxsulam intermediate, a low-boiling-point raw material with high toxicity, namely, chloromethyl methyl ether, is not required to be used in the synthesizing process; the safety of the synthesizing process is improved; the derivatives are favorable to industrialized production and application.

The invention belongs to the technical field of advanced nanocomposites, and particularly discloses a high-dispersity hollow anti-bell ringing type copper / silicon dioxide core-shell nanoparticle and a preparation method thereof. The preparation method comprises the following steps: synthesizing a copper nanoparticle with uniform morphology and size by adopting a high-temperature decomposition method; coating a layer of uniform silicon dioxide on the surface of the nanoparticle by using a cyclohexane / ammonia water reversed-phase micro-emulsion method so as to form a copper / silicon dioxide core-shell structure; and finally carrying out processing under an alkaline condition by utilizing a hydrothermal method so as to obtain the high-dispersity hollow anti-bell ringing type copper / silicon dioxide core-shell nanoparticle. The hollow anti-bell ringing type nanoparticle has the advantages of being high in copper metal dispersity, uniform in morphology and high in specific surface area, and has important application prospect in the fields of adsorptive separation and catalysis. According to a synthesis method provided by the invention, the control carried out on the specific surface area and copper dispersity of the hollow anti-bell ringing type core-shell nanoparticle can be realized. The synthesis raw materials are easy to get and the method is simple and rapid, so that large-batch synthesis can be realized.

The invention discloses a copper complex and the preparation method and application thereof, providing a cupric complex with 1, 10-phenanthroline, nitrate radical and N, N-dimethylfomamide. The preparation method of the cupric complex with 1, 10-phenanthroline is that nantokite, 1, 10-phenanthroline, nitrate radical and N, N-dimethylfomamide are mixed to react in solution to obtain the complex. The synthetic materials of the complex of the invention are easy to obtain and have low cost; the product precipitates in the form of crystalloid, thereby having a high purity and high production efficiency; besides, the complex can exist stably in natural states and has good water-solubility and fat-solubility; in addition, the complex of the invention has a good inhibiting effect on a plurality of cancer cells of lung cancer, liver cancer, adenocarcinoma of colon and so on, extensive effect and wide application range.

The invention belongs to the field of preparation of ionic hydrogen bond organic framework materials, and particularly discloses an ionic hydrogen bond organic framework material with proton conduction performance, the chemical formula of the ionic hydrogen bond organic framework material is {TPE-SO3H. 2 (DBD). 2 (DMF). 4 (H2O)} n, n is a positive integer, TPE-SO3H is 1, 1, 2, 2-tetrasulfonic acidphenyl ethylene, DBD is (C5NH4NH2) 22+, and DMF is N, N '-dimethylformamide. The structural unit belongs to a triclinic system, the space group is P-1, the molecular formula is C52H62N10O18S4, the cell parameters are as follows: alpha = 102.789 degrees, beta = 99.968 degrees and gamma = 112.169 degrees, each repetitive unit comprises four water molecules and two DMF molecules, two DBD molecules and one TPE-SO3H molecule, and amino groups on the DBD molecules and sulfonate groups on the TPE-SO3H molecule form a one-dimensional hydrogen bond network with water molecules. The material has good thermal stability, and has good performance for proton transportation. The invention discloses the preparation method of the material, the synthetic raw materials are easy to obtain, and the preparation process is simple. The ionic hydrogen bond organic framework material disclosed by the invention can be used as a proton conducting material and has a very good application prospect.

The invention relates to a sulfamic acid amphoteric surfactant and a synthesis method thereof, belonging to the technical field of organic compound synthesis. The synthesis method comprises the steps of: firstly synthesizing alkyl diamine or polyamine by using halohydrocarbon and diamine or polyamine in alkali condition, and secondly, reacting alkyl diamine or polyamine with halogenated sulphonating agent in alkali condition to synthesize a final product of sulfamic acid amphoteric surfactant. By controlling the reaction system at a certain alkaline pH value, the affects of hydrogen halide generated in the reaction process to equipment and the environment are overcome, meanwhile, the synthesis reaction speed and yield are improved, the final product has excellent surface activity property and hard water resistance, and can be applicable to the fields of development of oil and gas fields, corrosion inhibition of metal, surface cleaning, modification of fuel oil and the like.

The invention discloses a preparation method and application of blue-fluorescence carbon quantum dots, and belongs to the technical field of carbon quantum dots. Citric acid and hyaluronic acid are dissolved into water to obtain a mixed solution A; the mixed solution A is subjected to a hydrothermal reaction for 4-12 hours to obtain an HA-CDs solution; the HA-CDs solution is dialysed by using a dialysis membrane and then centrifuged, after standing, supernatant liquid is taken to obtain the blue-fluorescence carbon quantum dots. The hyaluronic acid and the citric acid are used as synthesizingraw materials, the novel carbon quantum dots high in fluorescence intensity is synthesized in one step, high-selectivity detection of folic acid can be achieved, and the carbon quantum dots which areeasily synthesized are applied in biological recognition.

The invention discloses a one-dimensional Bi-doped carbon nanowire composite material and a preparation method and application thereof. The one-dimensional Bi-doped carbon nanowire composite material is homogeneous in structure, regular and uniform in bismuth particle and completely embedded into carbon nanowires. The preparation method has the advantages of simple materials, availability to the materials, low price, simple synthesis method and environmental friendliness. The one-dimensional Bi-doped carbon nanowire composite material is high in cycling stability and specific capacity and capable of effectively inhibiting alloying volume expansion during cycling when used as lithium ion and sodion battery cathode materials, and is as high as 300 mAh g<-1> in capacity after 500 circles of cycling under the condition of 100 mA g<-1> and as high as 290 mAh g<-1> in capacity after 500 circles of cycling under the condition of 100 mA g<-1> when used as the lithium ion battery cathode material.

The invention relates to a hyperbranched polyether ester preparation method. Commercial bis-functionality haloalkane and tri-functionality hydroxyl / carboxyl are adopted as raw materials to realize one-pot synthesis of hyperbranched polyether ester through an A2+B3 polymerization method. The hyperbranched polyether ester preparation method is simple in procedures, the raw materials are easy to acquire, the prepared hyperbranched polyether ester contains high-reactivity end groups, and various functional groups or polymer chains can be introduced into the hyperbranched polyether ester by condensation reaction and ring opening reaction to prepare hyperbranched polymers with diversified performances and unique functions.

The invention discloses a phase change energy storage building material. The building material comprises the following components: ethylenediaminetetraacetic acid, toluene-2, 4-diisocyanate, a phase change material, cyclohexane, distilled water and an emulsifier; the invention further designs a preparation method of the phase change energy storage building material, and the preparation method comprises the flow of preparing an aqueous phase, emulsifying, polymerizing and separating product to obtain the phase change energy storage building material; the phase change energy storage building material can compound the phase change energy storage material with a proper building material to reinforce the storage capacity, and has good heat storage and temperature adjustment functions, the phase change energy storage building material is stable in chemical properties, free of toxic and irritating odor, low in cost and high in safety high, and the preparation method is simple and easy.