Application of non-surrounding displaced phthalocyanine zinc in preparing sonosensitizer

A zinc phthalocyanine, non-peripheral technology, applied in the application field of non-peripheral substituted zinc phthalocyanine in the preparation of sonosensitizers, which can solve the problems of sound sensitization ability to be improved, unstable composition and properties, and clinical application limitations , to achieve high stability, simple preparation and easy operation
CN102552907AActive Publication Date: 2012-07-11FUZHOU UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
FUZHOU UNIV
Publication Date
2012-07-11

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Abstract

The invention discloses application of non-surrounding displaced phthalocyanine zinc in preparing sonosensitizer, in particular discloses the non-surrounding displaced phthalocyanine zinc used as sonosensitizer in preparing sonodynamic therapy medicines. The non-surrounding displaced phthalocyanine zinc provided by the invention has a better biological compatibility, better biological selectivityand higher stability; and the preparation is simple, the operation is easy, synthetic raw materials are easy to obtain, and industrialization is easy to realize.
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Description

technical field

[0001] The invention belongs to the field of organic functional materials and medicines, and in particular relates to the application of non-peripheral substituted zinc phthalocyanine in the preparation of sound sensitizers. Background technique

[0002] In recent years, Sonodynamic Therapy (SDT) has received high attention as a new non-invasive and highly selective treatment method. The method is to use non-thermal ultrasound to activate the sound sensitizer in the target site, trigger a series of reactions, and generate active oxygen or other active substances, so as to kill tumor cells or other abnormal cells and achieve the purpose of treatment.

[0003] Sonodynamic therapy is established and developed on the basis of photodynamic therapy. Photodynamic therapy (PDT) uses light to activate the photosensitizer enriched in the target tissue to generate active oxygen and destroy the target tissue. With the development of photosensitizers and supporting lase...

Claims

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