37 results about "Hematoporphyrin" patented technology

Pharmaceutical formulation, its method of preparation, and its use. The pharmaceutical formulation contains peroxidic species or reaction products resulting from oxidation of an alkene, such as geraniol, by an oxygen-containing oxidizing agent, such as ozone; a penetrating solvent, such as dimethyl sulfoxide; a dye containing a chelated metal, such as hematoporphyrin; and an aromatic redox compound, such as benzoquinone. The pharmaceutical formulation is used to treat horses infected with Sarcocystis protozoal infections.

The use of a pharmaceutical formulation in treating coronary arteriosclerosis and a two-component pharmaceutical formulation. The pharmaceutical formulation contains peroxidic species or reaction products resulting from oxidation of an alkene, such as geraniol, by an oxygen-containing oxidizing agent, such as ozone; a penetrating solvent, such as dimithyl sulfoxide; a dye containing a chelated metal, such as hematoporphyrin; and an aromatic redox compound, such as benzoquinone.

A pharmaceutical formulation and its use. The pharmaceutical formulation contains peroxidic species or reaction products resulting from oxidation of an alkene, such as geraniol, by an oxygen-containing oxidizing agent, Su has ozone; a penetrating solvent, such as dimethylsulfoxide (''DMSO''); a dye containing a chelated metal, such as hematoporphyrin; and an aromatic redox compound, such as benzoquinone. The pharmaceutical formulation is used to effectively treat patients affected with cancer, such as lymphoma.

A method for destroying harmful cells is provided, applicable in treating proliferative diseases. The cells are destroyed by a combined treatment with a chemiluminescent agent and with a ligand-photosensitizer conjugate. The chemiluminescent agent emits light on reacting with oxygen species present in situ, the conjugate binds to the cell through its ligand and is activated by the emitted light, thereby destroying the cell. The method is demonstrated on a conjugate of transferrin-hematoporphyrin, which destroys cancerous cells in the presence of luminol.

A resin composition with a high crystallization rate that contains a polyalkylene furan dicarboxylate resin and a porphyrin compound, and a molded article composed of the resin composition. The polyalkylene furan dicarboxylate resin is preferably a polybutylene furan dicarboxylate resin. The porphyrin compound is preferably hematoporphyrin dihydrochloride. The molded article is obtained by molding the resin composition.

The invention provides a swainsonine derivative and a preparation method of a research reagent of the swainsonine derivative. The swainsonine is prepared through the following synthesis steps: a, adding chloroacetic acid and potassium hydroxide by taking swainsonine as a raw material and taking water as a solvent; b, feeding hematoporphyrin into thionyl chloride, and then adding cordycepin; and c, pouring the product obtained in the step a into the product obtained in the step b, and dropwise adding newly prepared potassium ethoxide into the obtained mixture, so that a swainsonine derivative solution is obtained. The swainsonine derivative disclosed by the invention is a product derived on the basis of a swainsonine structure, and by comparing, the difference is as follows: an enriched heterocyclic ring is connected, so that the swainsonine derivative disclosed by the invention has a function of enriching cancer cells, and can allow drugs to tend to parts with tumors but allow the drug concentration of other parts to be little.

The invention discloses a magnetic nanoparticle, the magnetic nanoparticle is Fe 3 o 4 The nanoparticle is the core, and the surface is coated with mesoporous silica, and the surface of the mesoporous silica material is modified with a photosensitizer and an embedded metal nanoparticle, and the photosensitizer is selected from hematoporphyrin, hematoporphyrin monomethyl ether, di Hydroporphine, one of 5-aminolevulinic acid. The magnetic nanoparticle prepared by the invention can be used as a nuclear magnetic resonance contrast agent to image and locate tumors, and then use the nuclear magnetic resonance imaging as a guide to perform photodynamic therapy on tumors.

The invention discloses a novel material containing biomimetic enzymes. The material uses PEI to synthesize gold nanoparticles. PEI is a positively charged polymer rich in imine groups and amine groups and has good water solubility. It can be combined with chloroauric acid Coordination of gold ions in the PEI, using the reduction of PEI branched chain amino groups to prepare gold nanoparticles with uniform particle size and stability. In addition, because the PEI molecule contains amino groups, it is easy to form an amide bond with Hemin, so that the Hemin molecule is connected to the PEI containing gold nanoparticles, and through centrifugation and separation and purification, a hematoporphyrin biomimetic material wrapped with gold nanoparticles is obtained. . This new type of material not only has the high catalytic performance of biomimetic enzymes, it can be used as an electrochemical probe to detect the content of pollutants in water, such as hydrogen peroxide, catechol, etc. On the other hand, due to the porous structure of the material itself, it can Dye molecules, such as methyl orange, rhodamine, etc., are adsorbed to protect the ecological environment.