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370 results about "Sapogenin" patented technology
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Sapogenins are the aglycones, or non-saccharide, portions of the family of natural products known as saponins. Sapogenins contain steroid or other triterpene frameworks as their key organic feature. For example, steroidal sapogenins such as tiggenin, neogitogenin, and tokorogenin have been isolated from the tubers of Chlorophytum arundinaceum. Some steroidal sapogenins can serve as a practical starting point for the semisynthesis of particular steroid hormones.
Topical Delivery System for Phytosterols
This invention relates to certain sugar esters of phytosterols of formula (I). These esters are useful for topical application, and for the treatment of skin condition, including age spots, acne, loss of cellular antioxidants, collagen loss, loss of skin pliability, loss of skin suppleness, skin wrinkles including fine lines, oxidation, damage from radiation, malfunction of matrix metalloproteases, malfunction of tyrosinases, damage from free radicals, damage from UV, dry skin, xerosis, ichthyosis, dandruff, brownish spots, keratoses, melasma, lentigines, liver spots, pigmented spots, dark circles under the eyes, skin pigmentation including darkened skin, blemishes, oily skin, warts, eczema, pruritic skin, psoriasis, inflammatory dermatoses, topical inflammation, disturbed keratinization, skin changes associated with aging, nail or skin requiring cleansers, conditioning or treatment, and hair or scalp requiring shampooing or conditioning, and combinations thereof;Wherein,n=0, 1, 2, or 3; andR=H, —CH2OH, —CH(OH)—CH2OH, —CH(OH)—CH(OH)—CH2OH; andR1=Substituent selected from a sapogenin, steroid, or terpenoid.
Owner:BIODERM RES
Methods for enhancing the transport of glucose into muscle
InactiveUS20050226948A1Effective quantityLow production costBiocideUnknown materialsCysteine thiolateTryptophan
The present invention is directed to novel compositions of bio-active compounds comprising 4-hydroxyisoleucine and one or more compounds selected from the group of amino acids, alkaloids, glycosides, volatile oils, saponins, sapogenins, mannans, flavonoids, fatty acids, vitamins and provitamins, minerals, and carbohydrates. Preferably, the novel compositions of bio-active compounds include 4-hydroxyisoleucine and one or more amino acids selected from the group consisting of arginine, aspartate, threonine, serine, glutamate, proline, glycine, alanine, cysteine, valine, methionine, isoleucine, leucine, tryptophan, phenylalanine, ornithine, proline, lysine, histidine, and gamma-aminobutyrate. The composition of bio-active compounds preferably include between about ten percent and about seventy percent of 4-hydroxyisoleucine and between about twenty percent and about forty percent of other amino acids. The bio-active compounds of the novel composition of the present invention may be derived, isolated, and / or extracted from Fenugreek seeds. A preferred method for extracting the bio-active compounds from Fenugreek seeds includes the steps of: (1) providing a plurality of Fenugreek seeds; (2) preparing the Fenugreek seeds; and (3) extracting a novel composition of bio-active compounds from the Fenugreek seeds, which include a preliminary extraction step and a secondary extraction step. The compositions of bio-active compounds have been found to be helpful in restoring healthy energy balance in humans and animals, aiding in weight management efforts, and for balancing blood sugar levels by way of assisting the body to make more efficient use of existing (i.e., endogenous) insulin.
Owner:TSI INC
Methods for affecting homeostasis and metabolism in a mammalian body
InactiveUS20050233014A1Effective quantityLow production costOrganic active ingredientsBiocideCysteine thiolateTryptophan
The present invention is directed to novel compositions of bio-active compounds comprising 4-hydroxyisoleucine and one or more compounds selected from the group of amino acids, alkaloids, glycosides, volatile oils, saponins, sapogenins, mannans, flavonoids, fatty acids, vitamins and provitamins, minerals, and carbohydrates. Preferably, the novel compositions of bio-active compounds include 4-hydroxyisoleucine and one or more amino acids selected from the group consisting of arginine, aspartate, threonine, serine, glutamate, proline, glycine, alanine, cysteine, valine, methionine, isoleucine, leucine, tryptophan, phenylalanine, ornithine, proline, lysine, histidine, and gamma-aminobutyrate. The composition of bio-active compounds preferably include between about ten percent and about seventy percent of 4-hydroxyisoleucine and between about twenty percent and about forty percent of other amino acids. The bio-active compounds of the novel composition of the present invention may be derived, isolated, and / or extracted from Fenugreek seeds. A preferred method for extracting the bio-active compounds from Fenugreek seeds includes the steps of: (1) providing a plurality of Fenugreek seeds; (2) preparing the Fenugreek seeds; and (3) extracting a novel composition of bio-active compounds from the Fenugreek seeds, which include a preliminary extraction step and a secondary extraction step. The compositions of bio-active compounds have been found to be helpful in restoring healthy energy balance in humans and animals, aiding in weight management efforts, and for balancing blood sugar levels by way of assisting the body to make more efficient use of existing (i.e., endogenous) insulin.
Owner:TSI INC
Composition comprising xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof
InactiveUS20050220910A1Preventing cerebral agingEnhance memoryBiocideSugar derivativesRheumatismHeadaches
This invention provides compositions, methods and process of producing extracts from Xanthoceras sorbifolia. The extract comprises alkaloids, coumarins, saccharides, proteins, polysaccharides, glycosides, saponins, tannins, acid, flavonoids and others. The composition can be used for treating cancer, arthritis, rheumatism, poor circulation, arteriosclerosis, Raynaud's syndrome, angina pectoris, cardiac disorder, coronary heart disease, headache, dizziness, kidney disorder, impotence and premature ejaculation; for preventing cerebral aging; for improving memory, cerebral functions; or for curing enuresis, frequent micturition, urinary incontinence, dementia, weak intelligence and Alzheimer's disease, autism, brain trauma, Parkinson's disease or other diseases caused by cerebral dysfunctions, and treating arthritis, rheumatism, poor circulation, arteriosclerosis, Raynaud's syndrome, angina pectoris, cardiac disorder, coronary heart disease, headache, dizziness, kidney disorder. This invention provides compounds comprising at least one sugar, a triterpene, such as Sapogenin, and at least one side chains at Carbon 21 and 22, such as Angeloyl groups. The compounds of the present have various pharmaceutical and therapeutic applications.
Owner:PACIFIC ARROW
Composition comprising Xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof
InactiveUS7524824B2Preventing cerebral agingEnhance memoryBiocideSugar derivativesSide chainProstate cancer
This invention provides compositions, methods and process of producing extracts from Xanthoceras sorbifolia. The extract comprises alkaloids, coumarins, saccharides, proteins, polysaccharides, glycosides, saponins, tannins, acid, flavonoids and others. The composition can be used for treating breast, leukocyte, liver, ovarian, bladder, prostate, bone or brain cancer. This invention provides compounds comprising at least one sugar, a triterpene, such as Sapogenin, and at least one side chains at Carbon 21 and 22, such as Angeloyl groups. The compounds of the present have various pharmaceutical and therapeutic applications, including treating breast, leukocyte, liver, ovarian, bladder, prostate, bone or brain cancer.
Owner:PACIFIC ARROW
Triterpene saponins, methods of synthesis, and uses thereof
The present invention relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, intermediates thereto, and uses thereof. QS-7 is a potent immuno-adjuvant that is significantly less toxic than QS-21, a related saponin that is currently the favored adjuvant in anticancer and antiviral vaccines. Tedious isolation and purification protocols have hindered the clinical development of QS-7. A novel semi-synthetic method is provided wherein a hydrolyzed prosapogenin mixture is used to synthesize QS-7, QS-21, and related analogs, greatly facilitating access to QS-7 and QS-21 analogs for preclinical and clinical evaluation.
Owner:SLOAN KETTERING INST FOR CANCER RES
Bindwood sapogenin and its preparation method and use
InactiveCN101125880AImprove the level ofLower blood sugarOrganic active ingredientsMetabolism disorderDiabetes mellitusNigella glandulifera
The invention relates to a hederagenin and a preparation method and purposes thereof. The compound is that the hederagenin is distilled from Nigella glandulifera freyn by degreasing, leaching and macroporous resin absorption, a structure of the hederagenin is confirmed by using physico-chemical constants, spectra database and single crystal method of X-ray diffractometry, the distilled hederagenin is proved in vitro to have the effect of tyrosine protein phosphatase PTP1B retardant and purposes as anti-diabetes drugs and health care products, meanwhile, the hederagenin is also applicable to be combination of drugs made from the compound or derivatives of the compound.
Owner:XINJIANG TECHN INST OF PHYSICS & CHEM CHINESE ACAD OF SCI
Cleaning production technique of 16-dehydro pregnenetrolone and its same kind compound
InactiveCN1475494AImprove utilizationEliminate environmental pollutionSteroidsCompound aOrganic solvent
Owner:SHANGHAI INST OF ORGANIC CHEM CHINESE ACAD OF SCI
Medical application of protopanaxatriol and protopanaxadiol in nervous system diseases
The invention relates to medical application of protopanaxa-triol (PPT), protopanaxadiol (PPD) and mixtures of the PPT and the PPD in any proportion in nervous system diseases, which are preferably used for treating and / or preventing epilepsy, cerebral ischemic diseases, memory disorder and parkinsonism syndrome.
Owner:王泽君
Application of ginseng secondary saponin and aliphatic ester derivative thereof in preventing and treating diabetes mellitus
InactiveCN102600189AImproves Glucose ToleranceOrganic active ingredientsMetabolism disorderGinsenosideFatty acid ester
The invention provides new application of ginseng secondary saponin and aliphatic ester derivative of the ginseng secondary saponin in preventing and treating diabetes mellitus. The ginseng secondary saponin and aliphatic ester derivative the ginseng secondary saponin can reduce blood sugar of the diabetics and improve glucose tolerance. The ginseng secondary saponin described by the invention mainly comprises RF1, RF3, Rh1, Mc, Mx, Rk1, Rk2, Rk3, Rh3, Rh4, Rg5, S-PPd, S-PPt and the like. The ginseng secondary saponin aliphatic ester described by the invention mainly comprises C-K aliphatic ester, Rh2 aliphatic ester, Rk3 aliphatic ester, Rh4 aliphatic ester, RF1 aliphatic ester, ginsengenin aliphatic ester and the like.
Owner:JILIN AGRICULTURAL UNIV
Method of protecting plants from bacterial and fungal diseases
Improved methods and compositions for protecting plants or seeds from plant diseases are provided. The compositions comprise (and preferably consist essentially of) saponin, such as triterpene type saponins extracted from quinoa or quillaja. Compositions according to the invention may comprise (or consist essentially of) a quantity of a sapogenin compound, preferably a sapogenins selected from the group consisting of oleanolic acid, hederagenin, phytolaccinic acid, and quillaic acid. The methods comprise contacting the portion of the plant (e.g., foliage, shoot, etc.) to be treated with a disease-inhibiting or protective amount of the composition. The compositions can also be used to treat plant seeds or tubers prior to planting thereof, as well as soil adjacent a growing plant. The inventive compositions are particularly useful for the treatment, control and / or prevention of bacterial diseases. The saponins of the invention can be applied as liquids or dry particulates, and are especially suited for the treatment of tomato and potato plants and their respective seeds.
Owner:NORTHERN QUINOA CORP
17 alpha, 22-dicarboxy furo compound and its use
This invention refers to 17alpha ,22 - dihydroxy Furan Steride compounds and its application. The compound' s structure formula is drawing in right graph, wherein the R1, R2 and R3 = H, C1-10 direct chain, cyclane group or alkenyl , triethylsilyl, dimethyl- tert-butylsilyl-biphenyl-tert-butylsilyl, methoxymethyl or tetrahydropyranyl. R4 = H see right formula a, b, C1-10 direct chain, cyclane group, alkenyl or alkynyl , R5 = C1-10 direct chain or cyclane group, R6 = H, C1-10 direct chain or cyclane group or alkenyl, triethylsilyl, dimethyl- tert-butylsilyl, biphenyl-tert-butylsilyl, methoxymethyl, tetrahydropyranyl. The start materials is diosgenin, which is easy available and cheap. Through F-cyclic degrading, the degradation product' s structure is converted into 17alpha,22 - dihydroxy furan steride compound. The compound again with F-cyclic restructure becomes the sapogenin, which is medicinal value. The process thereof is simple, adapted for industrialized production. It's glycoside of medicinal herbs Chonglou (Paris petiolata bak) sapogenin as one active ingredient, whose synthesis is provided herewith is effectively.
Owner:SHANGHAI INST OF ORGANIC CHEMISTRY - CHINESE ACAD OF SCI +1
Composition, extraction process and use of total triterpene sapogenin extracted from bamboo
InactiveCN1506373AEfficient extractionHigh precisionOrganic active ingredientsNervous disorderShootFriedelin
The present invention discloses the composition, extraction process and use of total triterpene sapogenin extracted from bamboo. The triterpene sapogenin is extracted from stem, branch, leaf, root, shoot, etc. of bamboo as one kind of gramineous plant via supercritical CO2 fluid extraction process. The test via vanillin-perchloric acid colorimetry method and GC-MS method shows that the extractive has total triterpene sapogenin content of 10-90 %, friedelin content of 5-35 % and lupenone content of 1-10 %. The extractive as one mixture of five-cycle triterpene compounds (EZR2002) has excellent physiological and pharmacological activity of resisting free radical, resisting oxidation, resisting tumor, lowering blood pressure, etc. and may be used in medicine and health care article for preventing and treating cardiac and cerebral vascular diseases and resisting tumor and may be also used in cosmetics.
Owner:张英 +1
Composition comprising xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof
InactiveUS20090263512A1Preventing cerebral agingEnhance memoryBiocideSugar derivativesRheumatismCoronary heart disease
Owner:PACIFIC ARROW
Triterpene saponins, methods of synthesis, and uses thereof
The present invention relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, intermediates thereto, and uses thereof. QS-7 is a potent immuno-adjuvant that is significantly less toxic than QS-21, a related saponin that is currently the favored adjuvant in anticancer and antiviral vaccines. Tedious isolation and purification protocols have hindered the clinical development of QS-7. A novel semi-synthetic method is provided wherein a hydrolyzed prosapogenin mixture is used to synthesize QS-7, QS-21, and related analogs, greatly facilitating access to QS-7 and QS-21 analogs for preclinical and clinical evaluation.
Owner:SLOAN KETTERING INST FOR CANCER RES
Therapeutic methods and uses of sapogenins and their derivatives
InactiveUS20110190249A1Increase synthesisFacilitated releaseOrganic active ingredientsSenses disorderMedicineSapogenin
The invention discloses therapeutic methods and uses of certain steroidal sapogenins, related compounds and derivatives thereof, in the treatment of non-cognitive neurodegeneration, non-cognitive neuromuscular degeneration, motor-sensory neurodegeneration or receptor dysfunction or loss in the absence of cognitive, neural and neuromuscular impairment.
Owner:PHYTOPHARM LTD
On-off total saponin as well as its extracting method and application
ActiveCN101161251AGood treatment effectIncrease carotid flowAntipyreticAnalgesicsCervical spondylosisArthritis
A dipsacus root total saponin is disclosed in the present invention, its weight percent accounts for 60 percent to 95 percent of dipsacus root medicinal materials extraction gross, and in dipsacus root total saponin 3-O-alpha-L-arabinopyranosyl-hederagenin-28-O-beta-D-glucopyranosyl(1-6)-beta-D-glucopyranoside accounts for 30 percent to 90 percent of dipsacus root medicinal materials extraction. A dipsacus root extracting method and its application in preparing medicine for treating cervical vertebra, arthritis, hyperosteogeny or osteoporosis are also disclosed in the present invention. By researching pharmacologic effect of the dipsacus root total saponin, finding that the dipsacus root total saponin prepared by the present invention has obvious anti-inflammation, pain-relieving, increasing carotid blood flow and decreasing blood viscosity, treating oestrogen deficiency type osteoporosis function, and has obvious prevention and cure for experimental cervical spondylosis, arthritis, hyperosteogeny or osteoporosis.
Owner:GUANGZHOU BOJI MEDICINE SERVICES
Smilax sapogenin derivative and preparation and applications thereof
InactiveCN102924559AHigh activityImprove solubilityOrganic active ingredientsNervous disorderDiseasePharmaceutical drug
The invention relates to a synthetic method and medical applications of a natural medicine rhizoma anemarrhenae smilax sapogenin structure derivative for resisting senile dementia. The high-purity rhizoma anemarrhenae sapogenin is used as a prodrug, and is subjected to structural modification methods such as inversion of configuration, oxidation, ammoniation, different degrees and locations of ring opening to increase the druggability, and pharmacology proves that the rhizoma anemarrhenae sapogenin has activity resisting senile dementia. The new application of the rhizoma anemarrhenae sapogenin and derivatives thereof in preparation of the medicine for resisting senile dementia is developed through the pharmacological activity.
Owner:SHENYANG PHARMA UNIVERSITY +1
Steroid compounds with endothelin receptor A antagonistic activity and intermediate thereof
InactiveCN101475623AHas endothelin receptor A antagonistic activityOrganic active ingredientsSteroidsSapogeninKetone
The invention provides a structure and a synthetic method thereof. The structure is obtained by modifying structures such as yam steroid sapogenin, proluton, dehydroepihydro-ketone and the like, and has an endothelin receptor A antagonistic active compound.
Owner:JIANGSU SIMCERE PHARMACEUTICAL R & D CO LTD
Use of hederagenin and its derivatives in preparing antidepressant product
InactiveCN101214250ALow toxicityIncrease contentOrganic active ingredientsNervous disorderDiseaseHypericum extract
The present invention relates to a novel purpose of hederagenin and a derivative of the hederagenin. An anti-depression test of the hederagenin and the derivative of the hederagenin shows obvious anti-depression activity, wherein, the salt derivative of the hederagenin has stronger anti-depression activity than the hederagenin; the hederagenin has stronger anti-depression activity than hederangenoside; the activities of the hederagenin and a hypericum extract are equivalent; sodium hederagenin has higher activity than the hypericum extract. The present invention has obvious pharmacological effect and stable quality; the raw material of the present invention has abundant source and cheap price and is safe with low toxin; the present invention has simple preparation technology and high yield, which provides novel medicine source for preventing, diagnosing, examining, protecting, remedying and researching on the depression and diseases directly related to the depression, is fit for the industrialization production, is easy for popularizing and applying and has very important value for developing and using Chinese officinal plant resource. Affective mental disorder is listed at top in Chinese disease general burden, and the research and manufacture of the drug for preventing and remedying the depression has obvious social benefit and economic benefit.
Owner:SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
Diosgenin piperazine derivatives and preparation method thereof
The invention relates to novel diosgenin piperazine compounds, a preparation method thereof and application of a medicinal composition taking the compounds as active ingredients in antitumor aspects. The preparation method comprises the steps of: preparing 1-sterides piperazine compounds from diosgenin and piperazine serving as raw materials; and reacting the 1-sterides piperazine compound with ArX to synthesize a series of 1-sterides-4-substituted piperazine compounds, wherein the 1-sterides-4-substituted piperazine compounds are expressed by general formulas (I) and (II). Pharmacological tests prove that the diosgenin piperazine compounds have the obvious inhibitory action on A375, A549 and HepG-2 cell strains, and are superior to diosgenin.
Owner:SICHUAN UNIV
Pure natural cleaning lotion
InactiveCN1952095AAdapt to different needsGood degreasingAmpholytes/electroneutral surface-active compoundsDetergent compounding agentsBetaineAdditive ingredient
The invention relates to a kind of natural cleaning dew. The characteristic of the invention is that all the materials of the cleaning dew are from nature, so the product is totally worthy of the name 'pure natural cleaning dew'. The betaine, tea sapogenin and coconut oil derivates are natural active compounds which have good quality of deoiling and decontaminating; the protease can remove the pesticide residue; the rice vinegar can sterilize different things; lemon essence can add incense and protect skin; the extracts of the traditional Chinese medicine have the function of heat-clearing and detoxicating, killing parasites to relieve itching, enriching skins and hair. Combining the previous ingredients scientifically can get different kinds of cleaning products to satisfy varied needs of customers, such as cleaning vegetables, eating apparatus and cookers or cleaning hands, hair and bodies.
Owner:吴煌发
Method for preparing pulsatilla chinensis (Bunge) Regel saponin matter and application of pulsatilla chinensis (Bunge) Regel saponin matter in preparation of antischistosomal medicament
ActiveCN102068445AOrganic active ingredientsSugar derivativesMedicinal herbsLiquid chromatography mass spectroscopy
The invention relates to a method for preparing a pulsatilla chinensis (Bunge) Regel saponin matter and application of the pulsatilla chinensis (Bunge) Regel saponin matter in preparation of an antischistosomal medicament. The pulsatilla chinensis (Bunge) Regel saponin matter is a single-component compound, and the method for preparing the pulsatilla chinensis (Bunge) Regel saponin matter comprises the following steps of: grinding the pulsatilla chinensis (Bunge) Regel medicinal materials into coarse powder, soaking by using ethanol, performing reflux extraction, condensing and drying, collecting dry extract, dissolving the dry extract in water, performing macroporous resin adsorption, and collecting the ethanol eluation part; and treating by using an opposite phase silica gel column, and collecting the eluation part of methanol and water to obtain the single-component compounds. According to the comparison with a comparison product and the LC / MS / MS test, the compounds are 3-O-alpha-L-rhamnopyranosyl-(1-2)-alpha-L-arabinopyranosyl-hederagenin28-O-alpha-L-rhamnopyranosyl-(1-4)-beta-D-glucopyranose-(1-6)-beta-D-glucopyranoside.
Owner:JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
Bulk medicament for treating orthopedic disorders and preparation method thereof
ActiveCN101366721AHigh purityImprove quality controlOrganic active ingredientsSkeletal disorderDiseaseMedicine
The invention discloses a bulk drug for treating orthopaedic diseases. The bulk drug is Chinese teasel root saponin VI and is prepared by extracting traditional Chinese medicinal materials which contain the Chinese teasel root saponin VI; the weight percentage content of the Chinese teasel root saponin VI occupies 95.0 to 99.9 percent of the total amount of an extract of the Chinese teasel root saponin VI; and the chemical name of the bulk drug is 3-O-alpha-L-arabopyranose ivy sapogenin-28-O-beta-D-glucopyranose(1-6)-beta-D-glucopyranoside. The invention also discloses a method for preparing the bulk drug - the Chinese teasel root saponin VI. The method comprises the following steps of extraction, concentration, separation of the total saponin, decolorization and purification and refinement. The preparation method has the advantages that the preparation method has high extraction rate and low cost, is safe and environment-friendly and is suitable for industrialized mass production. The invention also provides application of the bulk drug in preparing medicines for preventing and treating the orthopaedic diseases including osteoporosis, fracture and osteoarthritis.
Owner:博济医药科技股份有限公司
Ginseng stem leaf total sapogenin oral pharmaceutical preparation as well as preparation method and application thereof
The invention relates to a ginseng stem leaf total sapogenin oral pharmaceutical preparation as well as a preparation method and an application thereof, belonging to the field of traditional Chinese medicines. Total aglycone extracted from ginseng stem leaf is hydrolyzed to obtain ginseng stem leaf total sapogenin, and the ginseng stem leaf total sapogenin is made into an efficient preparation by matching with a special auxiliary material, thereby the bioavailability of the ginseng stem leaf total sapogenin can be greatly improved. The preparation has obvious curative effect in the aspect of curing diseases such as coronary heart disease, stenocardia, miocardial infarction, hepatitis, tumour, pulmonary heart disease, high blood pressure, and the like or the aspect of preventing depressive illness and senile-resistant.
Owner:北京凯瑞创新医药科技有限公司
Topical delivery system for phytosterols
This invention relates to certain sugar esters of phytosterols of formula (I). These esters are useful for topical application, and for the treatment of skin condition, including age spots, acne, loss of cellular antioxidants, collagen loss, loss of skin pliability, loss of skin suppleness, skin wrinkles including fine lines, oxidation, damage from radiation, malfunction of matrix metalloproteases, malfunction of tyrosinases, damage from free radicals, damage from UV, dry skin, xerosis, ichthyosis, dandruff, brownish spots, keratoses, melasma, lentigines, liver spots, pigmented spots, dark circles under the eyes, skin pigmentation including darkened skin, blemishes, oily skin, warts, eczema, pruritic skin, psoriasis, inflammatory dermatoses, topical inflammation, disturbed keratinization, skin changes associated with aging, nail or skin requiring cleansers, conditioning or treatment, and hair or scalp requiring shampooing or conditioning, and combinations thereof;Wherein,n=0, 1, 2, or 3; andR=H, —CH2OH, —CH(OH)—CH2OH, —CH(OH)—CH(OH)—CH2OH; andR1=Substituent selected from a sapogenin, steroid, or terpenoid.
Owner:BIODERM RES
Rusco saponin element and application of its saponin in preparation of medicine preventing and treating embolus disease
An application of ruscorectal and / or its heteroside prepared from ruscorectal and saccharide chain in preparing the medicine for preventing and treating thrombotic diseases is disclosed.
Owner:CHINA PHARM UNIV
Methods for deriving, isolating, and/or extracting amino acid compositions from Fenugreek seed
InactiveUS20050238738A1Effective quantityLow production costBiocideUnknown materialsCysteine thiolateTryptophan
The present invention is directed to novel compositions of bio-active compounds comprising 4-hydroxyisoleucine and one or more compounds selected from the group of amino acids, alkaloids, glycosides, volatile oils, saponins, sapogenins, mannans, flavonoids, fatty acids, vitamins and provitamins, minerals, and carbohydrates. Preferably, the novel compositions of bio-active compounds include 4-hydroxyisoleucine and one or more amino acids selected from the group consisting of arginine, aspartate, threonine, serine, glutamate, proline, glycine, alanine, cysteine, valine, methionine, isoleucine, leucine, tryptophan, phenylalanine, ornithine, proline, lysine, histidine, and gamma-aminobutyrate. The composition of bio-active compounds preferably include between about ten percent and about seventy percent of 4-hydroxyisoleucine and between about twenty percent and about forty percent of other amino acids. The bio-active compounds of the novel composition of the present invention may be derived, isolated, and / or extracted from Fenugreek seeds. A preferred method for extracting the bio-active compounds from Fenugreek seeds includes the steps of: (1) providing a plurality of Fenugreek seeds; (2) preparing the Fenugreek seeds; and (3) extracting a novel composition of bio-active compounds from the Fenugreek seeds, which include a preliminary extraction step and a secondary extraction step. The compositions of bio-active compounds have been found to be helpful in restoring healthy energy balance in humans and animals, aiding in weight management efforts, and for balancing blood sugar levels by way of assisting the body to make more efficient use of existing (i.e., endogenous) insulin.
Owner:TSI GROUP
Therapeutic methods and uses of sapogenins and their derivatives
The invention discloses therapeutic methods and uses of certain steroidal sapogenins, related compounds and derivatives thereof, in the treatment of non-cognitive neurodegeneration, non-cognitive neuromuscular degeneration, motor-sensory neurodegeneration or receptor dysfunction or loss in the absence of cognitive, neural and neuromuscular impairment.
Owner:PHYTOPHARM LTD
Method for preparing laxogenin by smilax scobinicaulis plants
InactiveCN101205249ANo pollution in the processSimple preparation processSteroidsPlant ingredientsSmilax scobinicaulisChemical synthesis
Owner:NORTHWEST A & F UNIV
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