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44results about How to "Good spectral properties" patented technology

Silicon phthalocyanine compound and composite, their preparation and application thereof

An axially substituted silicon-phthalocyanin match and its composition are disclosed, which have high optical spectrum characteristics and can be used as the photosensitizer used for photodynamic therapy to tumor and the diseases other than cancer, photodynamic diagnosis and photodynamic disinfecting.
Owner:FUZHOU UNIVERSITY

Use of non-periphery substituted phthalocyaniu metal complex

The present invention provides several application of non-peripheral substituted phthalocyanine metal coordination compound. The invented phthalocyanine metal coordination compound has the application for preparing photosensitive medicine preparation which can be used in photodynamic therapy or photodynamic diagnosis, and has the application for preparing photosensitizer which can be used in photodynamic purification or disinfection. Besides, it can be used as fluorescence probe or can be used for determining protein content.
Owner:FUZHOU UNIV

Method for preparing Y2O3:Tb<3+>@SiO2-NH2 fluorescence sensor array used for detecting organic chlorine pesticide

ActiveCN106092983AIncreased sensitivityStrong selective recognition abilityFluorescence/phosphorescenceSensor arrayHigh sensitive
The invention relates to a method for preparing a Y2O3:Tb<3+>@SiO2-NH2 fluorescence sensor array used for detecting an organic chlorine pesticide. The marking recognition sites in the fluorescence sensor array are mutually effected with organic chlorine pesticide molecules (target molecules), the target molecules and Tb<3+> on the recognition sites form an organic ligand through coordination, and change of the fluorescence intensity of Tb<3+> is used for detecting the target molecules. The method comprises the following three steps: preparing Y2O3:Tb<3+> fluorescent powder, then synthesizing a Y2O3:Tb<3+>@SiO2-NH2 fluorescence probe having capability for identifying the marking target molecules, finally, through a micromachining technology and a plasma etching method, dropping the fluid suspension of the fluorescence probe having the capability for identifying the marking target molecules on a silicon chip, naturally drying the silicon chip, and spontaneously putting the fluorescence probe materials in a micro hole to obtain the fluorescence sensor array for high-selectivity identification and high sensitive signal detection on the target molecules.
Owner:HEFEI UNIV

Phthalocyanine metal complex as well as preparation method and application thereof

The invention discloses a phthalocyanine metal complex as well as a preparation method and an application of the phthalocyanine metal complex. 3-[2,4,6-tri(dimethylamino methyl)-phenoxyl] phthalonitrile is prepared by using 2-phthalonitrile nitryl and 2,4,6-tri(dimethylamino methyl)-phenol as reactants, and further, the phthalocyanine metal complex substituted with amido or amido alpha bit is prepared. The phthalocyanine metal complex has the characteristics of high photosensitive activity and high water solubility; the phthalocyanine metal complex exists in water in a monomer mode, so that the photodynamic activity is facilitated in the water; the phthalocyanine metal complex is subjected to absorption spectroscopic redshift and shifted to a near-infrared area where is beneficial for penetrating through human tissues. The phthalocyanine metal complex is specially high in photodynamic antifungal activity and can be used for preparing photosensitizers or photodynamic medicines or photosensitive medicaments.
Owner:FUZHOU UNIV

Synthesis method of near infrared silver sulfide quantum dots

The invention discloses a synthesis method of near infrared silver sulfide quantum dots, belonging to the technical field of functional nanomaterials. The synthesis method comprises the following steps: (1) dissolving silver nitrate crystals into a polar solvent ethylene glycol, stirring at a dark place being 3 DEG C-5 DEG C until dissolving is achieved, so as to obtain a solution A; (2) under the stirring state, adding a mercaptan carboxylic acid solution to obtain a solution B; (3) placing the solution B under the condition of 70 DEG C to 80 DEG C and stirring at a dark place, reacting for 2min to 8min, so as to lead the solution B to gradually become milk white from colorless and gradually form silver sulfide crystal nucleus; (4) increasing the reaction temperature to 140 DEG C to 150 DEG C from 70 DEG C to 80 DEG C, continuously reacting, to gradually transform the milk white solution B into clear brown solution B, and form stable silver sulfide crystal nucleus; (5) rapidly cooling to room temperature and stopping reaction; and (6) ultrafiltering to remove the solvent and reaction side products, adding water for washing and dispersing, to obtain silver sulfide quantum dots. The method is simple and highly efficient, and can conduct mass production, the synthesized quantum dots are good in water phase dispersity, scattered and uniform in particle size and stable in optical property.
Owner:NORTHEASTERN UNIV

Preparation method for terpyridine pyridinium complex and application thereof in reverse transcriptase inhibition

The invention belongs to the field of research and development of HIV inhibitors, and discloses a preparation method for a terpyridine pyridinium (II) complex and application thereof in HIV reverse transcriptase inhibition. The structure of a cationic moiety of the terpyridine pyridinium (II) complex is as shown in a formula I. A preparation process for the terpyridine pyridinium (II) complex is optimized, the raw material cost is low, and the reaction time is short. The obtained complex is high in purity and yield and has good water solubility and excellent spectral properties. The terpyridine pyridinium (II) complex has the capability of selective binding to a TAR region on HIV RNA, and can block the reverse transcription process of viral RNA by reverse transcriptase and inhibit the replication of viral RNA. The terpyridine pyridinium (II) complex is a highly affinitive HIV RNA selective binding reagent and a highly active HIV reverse transcriptase inhibitor, and is an HIV drug having a great application potential.
Owner:YUNNAN UNIV

Axial nucleoside asymmetrically-modified silicon phthalocyanine and preparation method and application thereof

The invention discloses axial nucleoside asymmetrically-modified silicon phthalocyanine and a preparation method and application thereof, belonging to the preparation field of a photodynamic medicine or a photosensitizer. The axial nucleoside asymmetrically-modified silicon phthalocyanine disclosed by the invention can be applied to photodynamic treatment, photodynamic diagnosis or photodynamic disinfection as a photosensitizer, has the structural characteristic of axial asymmetric substitution, and shows good amphipathicity and excellent photodynamic activity.
Owner:FUZHOU UNIV

Phthalocyanine silicon modified by amino ethyl groups and phenoxy groups as well as preparation method and application thereof

The invention discloses phthalocyanine silicon modified by amino ethyl groups and phenoxy groups as well as a preparation method and application thereof, which belong to the field of the preparation of photodynamic medicines or photosensitizers. The phthalocyanine silicon modified by the amino ethyl groups and the phenoxy groups, which is provided by the invention, can be used as a photosensitizer for photodynamic therapy, photodynamic diagnosis or photodynamic disinfection, has the advantages of definite composition, simple and convenient preparation, high photodynamic activity and the like, is easy to realize industrialization and has obvious economic and social benefits.
Owner:FUZHOU UNIV

Silicon phthalocyanine axially bonded with piperidine or morpholine derivative with ester bond

The invention discloses a silicon phthalocyanine axially bonded with a piperidine or morpholine derivative with an ester bond as well as a preparation method and application of the silicon phthalocyanine and belongs to the field of preparing photodynamic drugs or photosensitizers. The silicon phthalocyanine can be used as a photosensitizer used for carrying out photodynamic antibacterium, photodynamic cancer resistance, photodynamically treating other diseases, photodynamic disinfection and photodynamic diagnosis and has the advantages of simple preparation, strong photosensitization and the like, and the maximum absorption spectrum is located in a near infrared region.
Owner:FUZHOU UNIV

Silicon phthalocyanine axially modified by aminoethyl phenoxyl and polyethylene glycol oligomer

ActiveCN103254223AGood amphipathyAsymmetric instead of uniqueAntibacterial agentsBiocidePhotosensOligomer
The invention discloses silicon phthalocyanine axially modified by aminoethyl phenoxyl and polyethylene glycol oligomer as well as a preparation method and application of silicon phthalocyanine, belonging to the field of preparation of photodynamic medicaments or photosensitizers. The silicon phthalocyanine provided by the invention can be used as a photosensitizer for photodynamic treatment, photodynamic diagnosis or photodynamic sterilization, has the structural characteristic of axially asymmetrical substitution and shows favorable amphipathy and extremely high photodynamic activity.
Owner:FUZHOU UNIV

Non-peripheral quaternary ammonium group modified zinc phthalocyanine as well as preparation method and application thereof

The invention discloses non-peripheral quaternary ammonium group modified zinc phthalocyanine as well as a preparation method and application thereof, and belongs to the field of preparation of photodynamic medicines or photosensitizers. The non-peripheral quaternary ammonium group modified zinc phthalocyanine provided by the invention can be used as a photosensitizer for photodynamic therapy andphotodynamic diagnosis, and can also be used for photodynamic-immune synergistic therapy. The unique structure of the polypeptide enables the polypeptide to be combined with an immune checkpoint blocking agent for use, so that the polypeptide has an excellent synergistic anti-tumor effect and has a remarkable application prospect in treatment of metastatic tumors.
Owner:FUZHOU UNIV

Phthalocyanine metal complex containing piperazine ethyoxyl modification group and preparing method thereof

The invention discloses a phthalocyanine metal complex containing piperazine ethyoxyl modification group and a preparing method thereof and belongs to the field of photodynamic drug preparing or photosensitizer preparing. The phthalocyanine metal complex containing piperazine ethyoxyl modification group is characterized in that the phthalocyanine metal complex has amphipathy and absorbs and sends spectrums to the wavelength position where the spectrums can pierce through human tissues in red shift mode, and photosensitizer is high in reactive oxygen production capacity. The preparing method is simple and has remarkable economic effect and social effect.
Owner:FUZHOU UNIV

A kind of phthalocyanine metal complex and its preparation method and application

The invention discloses a phthalocyanine metal complex as well as a preparation method and an application of the phthalocyanine metal complex. 3-[2,4,6-tri(dimethylamino methyl)-phenoxyl] phthalonitrile is prepared by using 2-phthalonitrile nitryl and 2,4,6-tri(dimethylamino methyl)-phenol as reactants, and further, the phthalocyanine metal complex substituted with amido or amido alpha bit is prepared. The phthalocyanine metal complex has the characteristics of high photosensitive activity and high water solubility; the phthalocyanine metal complex exists in water in a monomer mode, so that the photodynamic activity is facilitated in the water; the phthalocyanine metal complex is subjected to absorption spectroscopic redshift and shifted to a near-infrared area where is beneficial for penetrating through human tissues. The phthalocyanine metal complex is specially high in photodynamic antifungal activity and can be used for preparing photosensitizers or photodynamic medicines or photosensitive medicaments.
Owner:FUZHOU UNIV

Organosilicon group-modified fluorine-boron dipyrrole fluorochrome and preparation method and application thereof

The invention relates to the technical field of organic chemical industry and fine chemical engineering, and provides an organosilicon group-modified fluorine-boron dipyrrole fluorochrome and a preparation method and an application thereof, which solve all problems of a modification system based on carbon chemistry. Under inert gas protection, iodo BODIPY and silane-containing hydrogen are taken as the raw materials, under alkaline condition, the raw materials are subjected to a catalytic reaction for 24-72 hours in a solvent at room temperature, and the material is separated through silica-gel column chromatography to prepare the organosilicon group-modified fluorine-boron dipyrrole fluorochrome. The organosilicon group-modified fluorine-boron dipyrrole fluorochrome has excellent spectrum properties such as high molar extinction coefficient and high fluorescence quantum yield, can greatly increase the light stability, and is the ideal light functional material.
Owner:HANGZHOU NORMAL UNIVERSITY

Pericyclic monosubstituted amphiphilic phthalocyanine photosensitive agent as well as preparation and application thereof

The invention discloses a pericyclic monosubstituted amphiphilic phthalocyanine photosensitive agent as well as preparation and application thereof, which belongs to the field of preparation of photodynamic drugs or photosensitive agents. A compound of the invention has the characteristics that the amphipathy is realized, the structure is clear, nano particles which can be assembled into a quenching state in a physiological solution is realized, but the nano particles can be activated by albumin, and the pericyclic monosubstituted amphiphilic phthalocyanine photosensitive agent is an activatable targeting photosensitive agent.
Owner:FUZHOU UNIV

A silicon phthalocyanine with an axial ester bond linking piperidine or morpholine derivatives

The invention discloses a silicon phthalocyanine axially bonded with a piperidine or morpholine derivative with an ester bond as well as a preparation method and application of the silicon phthalocyanine and belongs to the field of preparing photodynamic drugs or photosensitizers. The silicon phthalocyanine can be used as a photosensitizer used for carrying out photodynamic antibacterium, photodynamic cancer resistance, photodynamically treating other diseases, photodynamic disinfection and photodynamic diagnosis and has the advantages of simple preparation, strong photosensitization and the like, and the maximum absorption spectrum is located in a near infrared region.
Owner:FUZHOU UNIV

Method for enhancing yellow emission intensity of YAG: Ce fluorescent powder

InactiveCN106957653AEnhanced yellow light emission intensityStrong yellow light emission intensityLuminescent compositionsAl powderLuminous intensity
The invention provides a method for enhancing yellow emission intensity of YAG: Ce fluorescent powder. The method comprises the following steps: by taking Al powder as a reducing agent, respectively filling the Al powder and YAG: Ce powder into a crucible boat, wherein the Al powder and the YAG: Ce powder are separately arranged, and a mass ratio of the reducing agent Al powder to the YAG: Ce powder is (0.03-1):1; and adding the powder into a vacuum tube furnace, and performing heating treatment at the temperature of 1000 DEG C for 6-10 hours. Compared with luminous intensity of YAG: Ce powder reduced at the temperature of 1000 DEG C for 8 hours by a 5% H2-95% N2 and CO reduction method, due to the same 460-nm blue light excitation, the YAG: Ce powder prepared by the method disclosed by the invention has high yellow emission intensity.
Owner:SHANGHAI INST OF TECH

A kind of metal porphyrin compound and its preparation method and application

The invention discloses a metalloporphyrin compound, its preparation method and application, and belongs to the technical field of medicinal chemistry. The metalloporphyrin compound represented by formula I of the present invention, or its optical isomer, pharmaceutically acceptable salt or solvate, has specific HIV RNA recognition and excellent HIV reverse transcriptase inhibition ability. The application of the compound of the present invention in the preparation of HIV TAR RNA selective recognition reagents, and the application of the preparation of HIV reverse transcriptase inhibitors.
Owner:YUNNAN UNIV

Method for processing special saddle point problem

The invention discloses a method for processing a special saddle point problem, which converts an original linear system into an equivalent linear system easy to solve and enables a preprocessing matrix P-1A to be provided with better spectral properties than an original matrix, so that the convergence speed of the algorithm is increased, and the calculation efficiency of the algorithm is improved; and the shielding effect is improved, the external interference is reduced, and data errors are prevented.
Owner:ZHENGZHOU UNIVERSITY OF AERONAUTICS

Phthalocyanine silicon modified by amino ethyl groups and phenoxy groups as well as preparation method and application thereof

The invention discloses phthalocyanine silicon modified by amino ethyl groups and phenoxy groups as well as a preparation method and application thereof, which belong to the field of the preparation of photodynamic medicines or photosensitizers. The phthalocyanine silicon modified by the amino ethyl groups and the phenoxy groups, which is provided by the invention, can be used as a photosensitizer for photodynamic therapy, photodynamic diagnosis or photodynamic disinfection, has the advantages of definite composition, simple and convenient preparation, high photodynamic activity and the like, is easy to realize industrialization and has obvious economic and social benefits.
Owner:FUZHOU UNIV

Silicon phthalocyanine modified by uridine derivatives and preparation method and application of silicon phthalocyanine

The invention discloses silicon phthalocyanine modified by uridine derivatives and a preparation method and application of the silicon phthalocyanine, and belongs to the field of preparation of photodynamic drugs or photosensitizer. The silicon phthalocyanine modified by the uridine derivatives can be used as a photosensitizer for photodynamic therapy, photodynamic diagnosis or photodynamic disinfection, has the advantages of high selectivity, high photodynamic activity and the like, and is explicit in composition and easy to prepare and industrialize.
Owner:FUZHOU UNIV

Silicon phthalocyanine modified by adenosine derivative and preparation method and application thereof

The invention discloses silicon phthalocyanine modified by an adenosine derivative and a preparation method and an application thereof, which belong to the field of preparation of photodynamic medicaments or photosensitizers. The silicon phthalocyanine modified by the adenosine derivative provided by the invention can be taken as a photosensitizer for use in photodynamic therapy, photodynamic diagnosis or photodynamic disinfection, has the advantages of high selectivity, high photodynamic activity and the like, has definite constitution, is easy and convenient to prepare, and is easy to be industrialized.
Owner:FUZHOU UNIV
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