5 results about "Benzoyl bromide" patented technology

This invention relates to the field of oilfield chemical additives technology, and discloses a method for preparing a 1-benzyl-10-phenylpyrrolo[1,2-a:3,4-b']dipyrazine-1-onium type quaternary ammonium salt high-temperature acidizing corrosion inhibitor. The method uses 2,2'-piperazine as the starting material, which undergoes a quaternization reaction with benzyl bromide to obtain a quaternary ammonium salt intermediate. The obtained intermediate undergoes an oxidative cyclization reaction with benzaldehyde and manganese dioxide in a dichloromethane system. After separation, drying, and purification, the target product is obtained. The preparation process of this invention is simple and easy to control, the product is easy to purify, and it is suitable for industrial production. It exhibits good synergistic effects with additives, excellent water solubility and compatibility, can stabilize and protect steel, reduce construction risks, and is suitable for various high-temperature acidizing operations.

The present application relates to a kind of cation macrocycle photosensitizer and its preparation method and application;Through triphenylamine derivative and p-benzyl bromide synthesis four cation macrocycle 1 molecule, 1 can be used as photosensitizer, the molecule can be through I / II type light reaction path to produce active oxygen, and under the condition of oxygen deficiency, biological molecule (NADH, BH4) is damaged to a large extent.In addition, further through the acylhydrazone bond of pH response, the polyethylene glycol (PEG) chain is modified on the molecule, obtains polyethylene glycol modified four cation macrocycle 1-PEG, through macrocyclic cation cavity, load tumor drug, self-assembly forms supramolecular nanoparticle, realizes the combined treatment of photodynamic and drug, system has remote operation and non-invasive, with drug release and acylhydrazone bond break, fluorescence emission intensity also gradually enhances, can be effectively navigated by fluorescence imaging drug treatment to tumor, thus it has wide application prospect in cancer diagnosis and treatment.

This invention belongs to the field of membrane material technology and discloses a high-flux, acid-resistant polyquaternary ammonium nanofiltration membrane and its preparation method. The method includes: (1) coating an aqueous solution containing cyclic tertiary nitrogen oligomers onto a porous support substrate membrane, wetting it, and then removing excess liquid; (2) subsequently coating the surface of the material obtained in step (1) with a hexane solution containing benzyl bromide, wetting it so that the tertiary nitrogen atoms on the cyclic tertiary nitrogen oligomers undergo a quaternization reaction with the benzyl bromide, gradually forming a dense separation membrane at the water-hexane interface; after the reaction is completed, it is dried to obtain the nanofiltration membrane. The nanofiltration membrane prepared by this invention overcomes the disadvantages of traditional polyquaternary ammonium membranes, which require several hours to prepare and have low permeability. A defect-free nanofiltration separation membrane can be prepared in just 1 minute. After soaking in 1M sulfuric acid for 30 days, it can still maintain high permeability and rejection rate, showing good application prospects.

This invention discloses a bipyrrole-based axially chiral phase transfer catalyst, its preparation method, and its application, belonging to the technical field of axially chiral phase transfer catalysts. The axially chiral compound (S)-1,9-diphenyl-5-((S)-1-phenylethyl)-5,6-dihydro-4H-dipyrrolo[1,2-b:2',1'-g][1,2,5]triazacycloheptane-3,7-dicarboxylic acid diethyl ester is used as a nucleophile to attack the partially positively charged carbon atom in the benzyl bromide reagent, replacing its bromide ion to generate a quaternary ammonium ion intermediate. The bromide ion attack causes the C-N bond to break, and the phenylethyl group on the quaternary ammonium ion intermediate detaches, forming a chiral tertiary amine with a benzyl group. Subsequently, it undergoes a quaternization reaction with excess benzyl bromide to obtain the chiral phase transfer catalyst. The prepared catalyst exhibits good catalytic activity in the [3+2] cycloaddition reaction of 2-(morpholine-4-carbonyl)allyl benzenesulfinate with phenylacryloylbenzene. The preparation method is simple and has broad application prospects.

The utility model discloses a kind of production devices of benzyl bromide, it is related to benzyl bromide production technical field, the inlet of reaction kettle is respectively communicated with formic acid tank, sulfuric acid tank, benzyl alcohol tank, purified water tank and bromine tank by pipeline, the top gas phase outlet of reaction kettle is communicated with reflux condenser by pipeline, the bottom outlet of reaction kettle is communicated with first liquid separator tank by pipeline, the oil phase outlet of first liquid separator tank is communicated with benzyl bromide product tank by pipeline.Using benzyl alcohol and bromine as main raw material, benzyl bromide is prepared by reaction, reaction selectivity is higher, by-product is significantly reduced, solve the problem that conventional toluene free radical halogenation method has many by-products, purification is complex, can directly obtain higher purity crude product by liquid separation initially.