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121 results about "Rheum Emodin" patented technology

Anti-stress and puffed mixed feed for ctenopharyngodon idellus and production method for feed

The invention relates to anti-stress and puffed mixed feed for ctenopharyngodon idellus and a production method for the feed. The mixed feed includes the following raw materials in mass percentage: 0-8% of meat and bone meal, 2-5% of broad bean albumen powder, 8-18% of soybean meal, 20-30% of rapeseed dregs, 10-15% of cottonseed meal, 10-20% of wheat, 10-20% of tapioca flour, 5-8% of rice bran, 2-4% of soya-bean oil, 0.2-0.4% of 50% choline chloride, 0.9-1.5% of monocalcium phosphate, 1-2% of vitamin premix, 1-2% of mineral premix, 1-2% of zeolite powder, 0.02-0.1% of GSH, 0.01-0.08% curcumin, 0.01-0.03% of tea polyphenol, 0.05-0.1% of taurine, 0.005-0.01% of rheum emodin, 0.01-0.02% of L-carnitine, and 0.02-0.03% of complex enzyme preparation. The anti-stress and puffed mixed feed improves the digestibility and deposition of feeding ctenopharyngodon idellus to nutrient substances of the feed, improves the immune, antioxidant and anti-stress ability of fish body and promotes growing of ctenopharyngodon idellus.
Owner:HUZHOU TEACHERS COLLEGE

Combined extraction and purification technique for multiple active ingredients of polygonum multiflorum

The invention relates to a combined extraction and purification technique for multiple active ingredients of a medicinal plant, in particular to a combined extraction and purification technique for multiple active ingredients of polygonum multiflorum. According to the method, stilbene glucoside, rheum emodin and chrysophanol in the polygonum multiflorum can be maximum extracted from the polygonum multiflorum into a solvent by using 70-80 percent of ethanol as an extraction solvent and are separated from starch in residual slag; water-soluble differences of the stilbene glucoside, the rheum emodin and the chrysophanol are used and water is used as a solvent so that the stilbene glucoside in alcohol extracts can be separated from the rheum emodin and the chrysophanol, and a crude product is obtained; the rheum emodin and the chrysophanol can be respectively separated from the alcohol extracts by successively using 5 percent of sodium carbonate and 5 percent of sodium hydroxide as solvents, and the rheum emodin and chrysophanol crude product can be obtained through an acid precipitation; and the polygonum multiflorum ethanol extract residual slag is washed by using water, and the starch with a purity of 85-87 percent can be obtained through precipitating water washing liquid. The invention has the characteristics of low cost, high efficiency, no pollution and high product purity.
Owner:JIANGSU UNIV

Chemical modification method capable of improving producing ability of reactive oxygen species (ROS) of rheum emodin

The invention relates to a chemical modification method capable of improving the anti-cancer activity of reactive oxygen species (ROS) through improving the producing ability of the ROS of rheum emodin. Experiments prove that a series of rheum emodin hyamines obtained by chemical modification to the rheum emodin have better anti-cancer activity on three kinds of cancer cells such as skin cancer A375, liver cancer HepG2 and stomach cancer AGS, and the anti-cancer activity and the producing ability of the ROS far exceeds those of the rheum emodin; moreover, experiments prove that the producing ability of the ROS and the anti-cancer activity of rheum emodin derivates are in positive correlation. The drug chemically modified by the chemical modification method has a certain selective killing effect on the cancer cells, and has a better prospect for development as an anti-cancer drug.
Owner:FUZHOU UNIV

Pharmaceutical composition suitable for mild disease of senile vascular dementia

The invention relates to a pharmaceutical composition suitable for mild disease of senile vascular dementia. The pharmaceutical composition is characterized by comprising 0.3-1.3g of tanshinone II A, 0.2-1.1g of ginsenoside Rg1, 0.075-0.3g of rheum emodin and 3.3-14g of pachymaran; preferably, the pharmaceutical composition also comprises components such as red flower, angelica sinensis, cinnamon, curcuma zedoary, euonymus alatus, caulis spatholobi, selaginella tamariscina, herba lycopi, rhodiola rosea, the fruit of Chinese wolfberry and the like for activating blood and tonifying qi.
Owner:SICHUAN GUANGDA PHARMA

Rheum emodin double-chain biquaternary ammonium salt with anti-cancer activity and preparation method of rheum emodin double-chain biquaternary ammonium salt

The invention discloses a rheum emodin double-chain biquaternary ammonium salt with the anti-cancer activity and a preparation method of the rheum emodin double-chain biquaternary ammonium salt. The rheum emodin double-chain biquaternary ammonium salt is a mixture of a rheum emodin 1,3-site biquaternary ammonium salt and a rheum emodin 3,8-site biquaternary ammonium salt. The preparation method comprises the following steps: performing Williamson etherification reaction on rheum emodin and p-benzyl bromide in the presence of K2CO3 so as to generate a mixture of 1,3-site dibromomethylbenzyl rheum emodin and 3,8-site dibromomethylbenzyl rheum emodin, and further reacting the dibromomethylbenzyl rheum emodin mixture with tertiary amine so as to obtain the mixture of 1,3-site biquaternary ammonium salt and rheum emodin 3,8-site biquaternary ammonium salt, wherein the two biquaternary ammonium salts are isomerides which cannot be separated on a chromatographic column. The anti-cancer activity evaluation shows that the activity of the rheum emodin double-chain biquaternary ammonium salt disclosed by the invention is higher than that of monoquaternary ammonium salt, and the rheum emodin double-chain biquaternary ammonium salt can be used in a medicine for treating malignant tumor, is particularly applicable to treatment on liver cancer, has a relatively small inhibition effect on normal cells, and has relatively great application prospect.
Owner:FUZHOU UNIV

Method for extracting bioactive ingredients in rhizoma polygoni cuspidati

The invention discloses a method for extracting bioactive ingredients in rhizoma polygoni cuspidati. The method includes the following steps that rhizoma polygoni cuspidati is taken, ground, screened with a 18-22-mesh sieve and put into a reflux tank; 75-85% ethyl alcohol with the weight 6-10 times that of rhizoma polygoni cuspidati is added, and reflux is carried out for 2.5-3.5 h at 55-65 DEG C; saturated ammonium sulfate is added into reflux liquid till precipitate is generated, and filtering is carried out to remove precipitate; ethyl alcohol is recycled, and alcohol extraction liquid is obtained; concentration is carried out, and concentrated extract is obtained; water precipitation is carried out, and supernatant liquid is taken; concentration is carried out again, and concentrated extract is obtained; alcohol dissolution is carried out, and supernatant liquid is taken; the supernatant liquid is subjected to plate ultrafiltration with SPES, and precipitate and supernatant liquid are collected; separation and purification of rheum emodin are carried out, wherein the purity of rheum emodin is 99.8%; the supernatant liquid is adsorbed with macroporous resin; separation and purification of polydatin are carried out, wherein the purity of polydatin is 99.5% or above; separation and purification of resveratrol are carried out, wherein the purity of resveratrol is 99.2% or above. According to the method, adopted equipment is simple, the process is simple and feasible, and industrial production is convenient; an adopted solvent is free of toxins or residues and does not cause environmental pollution.
Owner:HUNAN NUSTREETCARAX

Method for measuring effective ingredients of shenshuanning tablets

The invention relates to a method for measuring effective ingredients of shenshuanning tablets. The method includes the following steps of 1, preparing reference substance solutions, wherein proper quantities of reference substances including salvianic acid A sodium, salvianolic acid B, hesperidin, berberine hydrochloride, aloe-emodin, rheum emodin, rheinic acid, chrysophanol and emodin monomethyl ether are taken and precisely weighed, and methyl alcohol is added to prepare solutions; 2, preparing reference medicinal material solutions, wherein radix pseudostellariae powder, coptidis rhizome powder, rhizoma pinelliae powder, dried tangerine powder, poria cocos powder, rheum officinale powder, powder of the root of red-rooted salvia, powder of the root of bidentate achyranthes, safflower powder and licorice root powder are taken and precisely weighed, and methyl alcohol is added to prepare solutions; 3, preparing a solution for a test product, wherein sample powder is taken and precisely weighed, and methyl alcohol is added to prepare the solution; 4, carrying out a measuring method, wherein 5 microliters to 15 microliters of the solutions are respectively taken and respectively injected into a liquid chromatograph for testing, and chromatograms are recorded and compared with standard fingerprints.
Owner:QINHUANGDAO SHANHAIGUAN PHARMA CO LTD

Bushy knotweed leaf fingerprint HPLC method and its use in bushy knotweed leaf capsule quality control

ActiveCN106018629AHigh separation of chromatographic peaksSolving Quality Control IssuesComponent separationGoniothalamusHplc method
The invention provides a bushy knotweed leaf fingerprint HPLC method. The method comprises preparation of a sample to be detected and HPLC detection of the sample. The method can simultaneously detect 12 index components such as gallic acid, chlorogenic acid, ferulic acid, polydatin, rutin, isoquercitrin, quercitrin, resveratrol, quercetin, rheum emodin, chrysophanol and physcion in bushy knotweed leaf raw drugs and their products. The bushy knotweed leaf fingerprint HPLC method has a chromatographic peak resolution, realizes retention time stabilization of different samples and solves the bushy knotweed leaf capsule quality control problems.
Owner:云南海沣药业有限公司

Analysis method for four anthraquinones in blood plasma and application of four anthraquinones in pharmacokinetics

The invention discloses an analysis method for determining rheum emodin, aloe-emodin, chrysophanol and emodin monomethyl ether in blood plasma at the same time and application of rheum emodin, aloe-emodin, chrysophanol and emodin monomethyl ether in pharmacokinetics, wherein the analysis method for determining rheum emodin, aloe-emodin, chrysophanol and emodin monomethyl ether in the blood plasma at the same time comprises the following steps: (1) preparing a sample; (2) detecting. The analysis method for determining rheum emodin, aloe-emodin, chrysophanol and emodin monomethyl ether in the blood plasma at the same time has good specificity, high precision degree, high accuracy and wide linear range and can be used for in vivo pharmacokinetic determination of Chinese medicinal compositions.
Owner:北京中一堂科技有限公司

High-purity resveratrol preparation method

The invention discloses a high-purity resveratrol preparation method which comprises (1) pulping or crushing a bulk drug polygonum cuspidatum; (2) taking 30%-90% ethyl alcohol as a solvent to conduct pot group type dynamic countercurrent extraction, conducting vacuum concentration after extraction until no alcohol flavor exists, and keeping the mixture for later use; (3) adding a complex enzyme preparation to conduct enzymolysis, and concentrating and filtering after enzymolysis to obtain a crude product; (4) extracting the obtained crude product by using methyl alcohol, drying the extract to obtain a by-product rheum emodin, and enabling the extract liquor to be subjected to alumina column alumina column chromatography, methyl alcohol analysis, concentration, gasoline washing, activated carbon decoloration, ethyl alcohol crystallization and drying to obtain the high-purity resveratrol. According to the invention, extraction and then enzymolysis are conducted to convert the polygonin, so that the conversion time is shortened, the adoption of the dynamic countercurrent and the combination of vacuum pulse improve the extraction rate, the environment protecting production of the resveratrol with short period, less steps and low loss is implemented, and the application prospect is wide.
Owner:江苏桂柳牧业集团有限公司

Tea polyphenol, naringin or rheum emodin modified PP spunbonded non-woven cloth and preparation method

The invention relates to tea polyphenol, naringin or rheum emodin modified PP spunbonded non-woven cloth. The tea polyphenol, naringin or rheum emodin modified PP spunbonded non-woven cloth is prepared from the tea polyphenol, the naringin or the rheum emodin, and the mass percent of the tea polyphenol, the naringin or the rheum emodin is 0.1-5%. According to the tea polyphenol, naringin or rheumemodin modified PP spunbonded non-woven cloth, the tea polyphenol, the naringin or the rheum emodin and porous nano-materials are subjected to modified process, the porous nano-materials have the large specific surface area, the tea polyphenol, the naringin or the rheum emodin is packed in a porous material hole channel, so that components of the tea polyphenol, the naringin or the rheum emodin are not damaged when the non-woven cloth is prepared later, and thus the performance of the non-woven cloth is improved. A fat soluble solvent is added into the modified nano composite materials for grinding and uniform dispersing, the modified nano composite materials are subjected to mixing and silk-spraying with PP slices, the modified PP spunbonded non-woven cloth is obtained, and the softness,air permeability and water-absorbing quality of the non-woven cloth can be improved.
Owner:BESTEE MATERIAL (TSINGTAO) CO LTD

Modified ES fiber containing tea polyphenol, naringin or rheum emodin and preparing method of modified ES fiber

The invention relates to a modified ES fiber containing tea polyphenol, naringin or rheum emodin. The modified ES fiber comprises the tea polyphenol, naringin or rheum emodin, wherein the mass percentage of the tea polyphenol, naringin or rheum emodin is 0.1-5%. According to the modified ES fiber, the tea polyphenol, naringin or rheum emodin and a porous nanometer material are modified. Since theporous nanometer material has a large specific surface area, the tea polyphenol, naringin or rheum emodin is encapsulated in a pore channel of the porous material, so that the situation that components of the tea polyphenol, naringin or rheum emodin are damaged when the ES fiber is prepared in the later period is avoided, and the performance of the ES fiber is improved. By adding the tea polyphenol, naringin or rheum emodin, the antibacterial property, mechanical property and hygroscopic property of the ES fiber can be improved. According to the preparation of the ES fiber, by preparing functional master batches at first and then conducting blend spinning, the homogeneity of the ES fiber can be improved, and the performance of the ES fiber is improved.
Owner:BESTEE MATERIAL (TSINGTAO) CO LTD

Rheum emodin single-chain biquaternary ammonium salt with antitumor activity and preparation method thereof

The invention discloses rheum emodin single-chain biquaternary ammonium salt with antitumor activity and a preparation method thereof. The rheum emodin single-chain biquaternary ammonium salt is double protected site-6 rheum emodin biquaternary ammonium salt or double deprotected site-6 rheum emodin biquaternary ammonium salt. The preparation method comprises the following steps: carrying out reaction on 1,4-diiodobutane and methyl dioctyl tertiary amine or methyl didecyl tertiary amine to obtain iodobutyl quaternary ammonium salt; carrying out reaction on double protected rheum emodin or double deprotected rheum emodin and dimethylamine to obtain double protected rheum emodin tertiary amine or double deprotected rheum emodin tertiary amine; and carrying out nucleophilic substitution with iodobutyl quaternary ammonium salt to obtain the rheum emodin single-chain biquaternary ammonium salt. An in-vitro cancer cell inhibiting test verifies that the rheum emodin single-chain biquaternary ammonium salt has good antitumor activity, wherein the double deprotected site-6 rheum emodin biquaternary ammonium salt can be used for effectively inhibiting growth of liver cancer HepG2 and is relatively less in toxic and side effects on normal cells. The rheum emodin single-chain biquaternary ammonium salt can be used as an anti-malignant tumor drug, is particularly suitable for treating liver cancer, and has relatively huge application prospect.
Owner:FUZHOU UNIV

Bitter aversive agent and preparation method thereof

The invention discloses a bitter aversive agent and a preparation method thereof. The aversive agent can consist of a bitter substance carrier, a bitter substance and additives. According to the bitter aversive agent and the preparation method thereof provided by the invention, a fresh aloe original fluid is taken as the bitter substance carrier and is matched with a small quantity of chondroitin, and the bitter substance, assisted by two materials, namely the aloe and the chondroitin, can easily permeate into fingernails and subcutaneous tissues; and after 5min of washing a hand coated with the bitter aversive agent, bitterness is still quite strong. The aversive agent is convenient to coat; the aversive agent is applicable to both the fingernails and skin, and the aversive agent is washing-resistant, wear-resistant, free from preservatives and free from toxic and harmful materials; such allergic substances as calcium oxalate, rheum emodin and the like in aloe leaves are effectively eliminated in a process of preparing the bitter substance carrier, so that the bitter aversive agent is quite suitable for young people and children. The aloe ingredient and the chondroitin are also conducive to the repair of collagen tissues in nail beds and the skin, so as to promote the growth of the nail beds and the repair of the hand skin.
Owner:周国文

Application of Lvji cough asthma tablets to preparation of medicine for inhibiting cell proliferation of prostate cancer cells PC-3

The invention belongs to the technical field of traditional Chinese medicine and particularly relates to application of cough asthma tablets to preparation of medicine for inhibiting cell proliferation of prostate cancer cells PC-3 and a preparing method for the cough asthma tablets. The cough asthma tablets are prepared from 200 g of ll-grass of creeping bulbophyllum, 200 g of paederia scandens, 100 g of mahonia fortuneiFedde, 100 g of marsdenia tenacissima, 100 g of rhizoma bletillae, 100 g of polygonum cuspidatum, 100 g of speranskia tuberculata andd 100 g of rhizoma polygonati by the adoption of supercritical extraction. The rheum emodin content is increased greatly.
Owner:济南新时代医药科技有限公司

Method for establishing substance standard of taohe chengqi decoction

The invention relates to a method for establishing the substance standard of a taohe chengqi decoction, and belongs to the technical field of Chinese pharmaceutical manufacturing. The method comprisesthe following steps: an extraction process is established, through high-performance liquid chromatography, effective component chromatography is determined, the content is measured, the paste rate ismeasured, and a fingerprint spectrum is established. Firstly, the traditional taohe chengqi decoction is prepared based on a traditional preparation process, the paste rate is measured and determined, a fingerprint spectrum common model is established by adopting the high-performance liquid chromatography, the chromatographic peak is identified through a reference substance, on the basis, the content of amygdalin, rhein, rheum emodin, chrysophanol, physcion, aloe-emodin, cinnamaldehyde and glycyrrhizic acid is measured, and the method can be used for quality inspection of the taohe chengqi decoction.
Owner:HEBEI UNIV OF CHINESE MEDICINE

Compound medicine composition with lung cancer resistant effect and application of compound medicine composition

The invention belongs to the field of natural medicine, and discloses a compound medicine composition with a lung cancer resistant effect and application of the compound medicine composition. Active ingredients of the compound medicine composition consist of piperlongumine and rheum emodin in a molar ratio of (1:1) to (1:10). By combining the piperlongumine and rheum emodin, a synergic effect for treating the lung cancer is relatively good.
Owner:佛山市第五人民医院 +1

Composition as well as nano-micelle containing composition and application thereof

The invention belongs to the field of research and development of drugs and in particular relates to a composition as well as nano-micelle containing the composition and application thereof. The invention provides a composition, and the composition contains the following raw materials: docetaxel, traditional Chinese medicine monomers and a carrier, wherein the traditional Chinese medicine monomerscontains one or more of quercetin, curcumin, rheum emodin, cnidium lactone, apigenin, baicalein, kaempferol and silymarin. The invention further provides a preparation method of the nano-micelle containing the composition. The invention further provides application of the composition or the product prepared by the preparation method in inhibition of tumor cell proliferation and / or survival. According to experimental determination, the product prepared by the technical scheme provided by the invention has obvious antineoplastic activity after oral medication, is high in bioavailability and capable of obviously reducing the dosage and can overcome drug resistance produced during single use of the docetaxel.
Owner:GUANGDONG MEDICAL UNIV

Traditional Chinese medicine soluble powder for treating piglet diarrhea

The invention relates to traditional Chinese medicine soluble powder for treating piglet diarrhea and a preparation method thereof.The traditional Chinese medicine soluble powder for treating the piglet diarrhea is mainly prepared by mixing, by weight, 20-40 parts of rhizoma coptidis, 20-40 parts of rheum officinale, 20-40 parts of folium isatidis, 10-15 parts of honeysuckle leaves, 5-10 parts of licorice roots and 0.1-0.3 part of a sweetening agent.The production method comprises the steps that the components are cleaned, dried and smashed to be 40-80 mesh, purified water is added, ultrasonic extracting, clarifying, filtering, concentrating and spray drying are performed, and then the traditional Chinese medicine soluble powder is obtained.The traditional Chinese medicine soluble powder for treating the piglet diarrhea contains berberine, chlorogenic acid, rheum emodin, flavone and immune substance, can be used for prevention and treatment on diarrhea of various piglets and especially used for antibiotic-free pig raising and is significant in disease prevention and treatment effect, simple in preparation technology and capable of saving energy sources and time and easily achieving industrialized production.
Owner:NANNING BAIJI BIOLOGICAL ENG

Heat clearing and hematostatic Mongolian medicine and preparation technology thereof

ActiveCN107582899AHas heat-clearing, cooling blood and hemostasis effectSmall toxicityOrganic active ingredientsInorganic phosphorous active ingredientsCholic acidSide effect
The invention relates to medicine and a preparation technology thereof, namely heat clearing and hematostatic Mongolian medicine and preparation technology thereof. The Mongolian medicine is characterized by being prepared from the following active ingredients in parts by weight: 1 to 2 parts of gardenoside, 1 to 2 parts of rutin, 1 to 2 parts of carthamin, 1 to 2 parts of beta-sitosterol, 1 to 2parts of rheum emodin, 1 to 2 parts of glycyrrhizic acid, 1 to 2 parts of kutkin, 1 to 2 parts of rubican, 1 to 2 parts of alkannin, 1 to 2 parts of shellac resin, 3 to 5 parts of calcium carbonate, 3to 5 parts of calcium phosphate, 3 to 5 parts of amino acid, 2 to 3 parts of cholic acid and 2 to 3 parts of calculus bovis. The Mongolian medicine has the beneficial effects of heat clearing, bloodcooling and hematostatic effects, obvious curative effects on hemorrhage syndromes of hematemesis, hemafecia, menorrhagia, traumatic bleeding, liver diseases and the like, low toxic and side effect, wide suitable crowd range, convenience in taking, convenience in digestion and absorption and quick effect; thus, the Mongolian medicine hopefully becomes typical medicine for treating lung diseases.
Owner:内蒙古民族大学附属医院

Medicine composition for treating acute or chronic cholecystitis and acute or chronic pancreatitis

The invention relates to a medicine composition for treating acute or chronic cholecystitis and acute or chronic pancreatitis, which belongs to the field of Chinese medicines and is prepared by saikosaponin 8-15 parts, baicalin 5-12 parts, magnolol 7-16 parts, rheum emodin 1-5 parts, immature total bitter orange flavonoid 9-18 parts, caffeic acid 8-16 parts, paeoniflorin 7-13 parts, chlorogenic acid 10-17 parts, rhizoma pinellinae praeparata 7-13 parts and glycyrrhizic acid 2-7 parts. The medicine composition for treating acute or chronic cholecystitis and acute or chronic pancreatitis has the advantages that the medicine has anti-inflammation, analgesia and antibacterium functions according to Chinese medicine theories and modern pharmacological experimental methods, has a main function of cleaning and discharging liver-gallbladder damp and heat, and is used for acute or chronic cholecystitis and acute or chronic pancreatitis.
Owner:JILIN ZIXIN PHARMA

Improved method of synthesizing emodin

This invention relates a synthesizing and reforming method for rheum emodin, which takes 3, 5-dinitroalizaric acid as the starting material to be reacted through Ke Fu acylation, recovery, circulation and diazo reactions to get the total yield of 50.8%, in which, nitryl is recovered by catalyzation and hydrogenation, oil of vitriol and acetic acid as the medium, glycol mono-aether as the assistant solvent to increase the reaction yield rate of diazo reaction.
Owner:NANJING RALLY BIOCHEM

Plant extract composition with vascular cleaning function and preparation method thereof

The invention discloses a plant extract composition functioning as a dustman of blood vessels and a preparation method thereof. The plant extract composition mainly comprises plant raw materials and an extract, wherein the raw materials include the following components according to parts by weight: 10 to 30 parts s of dyers woad leaves, 15 to 35 parts of cassia seed, 10 to 20 parts of inular flowers, 15 to 30 parts of safflower, 10 to 30 parts of chrysanthemum and 20 to 50 parts of apocynum; and the extract includes the following components according to parts by weight: 20 to 40 parts of gingko flavone, 20 to 35 parts of rheum emodin, 30 to 50 parts of crataegin, 15 to 55 parts of gypenoside and 20 to 60 parts of panax notoginseng saponins. The plant raw materials are processed by the operations of pulverization, steeping, ultrasonic extraction, separation, filtration, PH value adjustment and concentration; then, the extract is added to the plant raw materials. The product obtained by drying the mixture of the plant raw materials and the extract can increase the level of the high density lipoprotein in blood, smoothen and soften the blood vessels, lower the blood viscosity, and function as the dustman of blood vessels.
Owner:杜志政 +1

Anti-hyperuricemia active ingredient group of polygonum cuspidatum and preparation method and application thereof

InactiveCN104721204AGood curative effectMeet the needs of preparing products for the treatment of hyperuricemiaOrganic active ingredientsSugar derivativesD-GlucopyranoseMedicine
The invention provides an anti-hyperuricemia active ingredient group of polygonum cuspidatum and a preparation method thereof. The anti-hyperuricemia active ingredient group contains 5-20wt% of cassia ketone-8-O-beta-D-glucopyranoside, 20-30wt% of rheum emodin-6-O-beta-D-glucopyranoside, 30-50wt% of rheum emodin-8-O-beta-D-glucopyranoside and 10-20wt% of physcion-8-O-beta-D-glucopyranoside; the invention further discloses an application of the anti-hyperuricemia active ingredient group of polygonum cuspidatum in preparation of products for treating hyperuricemia.
Owner:QINGDAO UNIV

Anti-acne serum and preparation method thereof

The invention belongs to the field of cosmetics, and concretely relates to an anti-acne serum and a preparation method thereof. The invention provides the anti-acne serum, which is prepared from the following components in percentage by weight: 2 to 4 percent of tea tree oil, 1 to 3 percent of rheum emodin, 1 to 2 percent of cinnamic acid, 1 to 2 percent of berberine, 1 to 3 percent of dipotassium glycyrrhizinate, 1 to 2 percent of barbaloin, 0.5 to 1.5 percent of hyaluronic acid, 1 to 2 percent of squalane, 1 to 3 percent of glycerinum, 3 to 5 percent of butanediol, 0.1 to 0.3 percent of xanthan gum, 0.1 to 0.3 percent of methyl-p-hydroxybenzoate, and 71.9 to 87.3 percent of water. According to the anti-acne serum provided by the invention, propionibacterium acnes can be effectively inhibited, the production of skin acnes can be reduced fundamentally, an effect on removing the acnes is achieved, and the clinical efficacy rate is 98 percent. Meanwhile, the anti-acne serum provided by the invention also has the efficacies on clearing away heat and toxic materials, desensitizing, diminishing inflammation and moisturizing, has no toxicity and stimulation, and is safe, effective, and easy to absorb.
Owner:JIANGXI YIXINTANG MEDICAL TECH

Medicine for hyperlipemia and atherosclerosis treating and preparation method and application

The invention discloses medicine for hyperlipemia and atherosclerosis treating and a preparation method and an application. The medicine is prepared by raw materials, by weight, 80-100 parts of rheum emodin and 4-6 parts of aloe emodin which are active ingredients in a polygonum multiflorum free anthraquinone derivant. The invention discloses the novel application for the polygonum multiflorum free anthraquinone derivant, a wide application prospect and a medicinal value are provided for the research for polygonum multiflorum which serves as traditional old medicine and active ingredients of the polygonum multiflorum. The active ingredients such as the rheum emodin and the aloe emodin which are screened in the polygonum multiflorum free anthraquinone derivant serve as the raw materials, the prepared medicine has an obvious effect on aspects such as the hyperlipemia treating and AS treating, and the good application prospect is obtained.
Owner:GUIYANG COLLEGE OF TRADITIONAL CHINESE MEDICINE

Medicinal composition for treating psoriasis

The invention relates to a medicinal composition for treating psoriasis. The medicinal composition comprises the active ingredients of lysozyme and rheum emodin which are in the weight ratio of (1:10)-(10:1). Compared with a common Western medicinal preparation, a lysozyme preparation of the medicinal composition is simple in preparation method and reasonable in compatibility; the two active ingredients give play to respective effects, and meanwhile, can generate a synergetic effect; the psoriasis is treated remarkably; the lysozyme and the rheum emodin are sourced naturally and are safe and non-toxic, and have no side effect; the medicinal composition does not contain a Western medicinal component, so that the medicament has no medicament resistance.
Owner:ZHEJIANG AEGIS BIOLOGICAL SCI & TECH CO LTD

Quality control method for capsules with functions of dispelling wind and removing toxicity

The invention provides a detection method for capsules with functions of dispelling wind and removing toxicity. The detection method is used for detecting hastatoside, verbenalin, polydatin, forsythiaside A, verbascoside, glabrolide monoammonium salt and rheum emodin in the capsules simultaneously with a high-efficiency liquid chromatography, wherein the high-efficiency liquid chromatography is performed under following conditions: a chromatographic column adopts octadecyl-silane-bonded silica gel as a filling material; mobile phases comprise a mobile phase A which is acetonitrile and a mobile phase B which is an acidic aqueous solution, and gradient elution is carried out; the flow velocity is 1.0ml / min; the column temperature is 30 DEG C; the detection wavelength is 210nm-400nm; and the number of theoretical plates is calculated according to rheum emodin peaks, and is not less than 5000. According to the detection method provided by the invention, the content of seven active components such as hastatoside, verbenalin, polydatin, forsythiaside A, verbascoside, glabrolide monoammonium salt and rheum emodin in the capsules can be detected simultaneously, so that the active components of the capsules with functions of dispelling wind and removing toxicity can be comprehensively represented. The detection method has the characteristics of high precision, stability and repeatability.
Owner:安徽济人药业股份有限公司

Preparation method of porcine epidemic diarrhea virus liposome diluent freeze-dried product

The invention belongs to the technical field of veterinary biological products, and in particular relates to a preparation method of a porcine epidemic diarrhea virus liposome diluent freeze-dried product, and the method comprises the following steps: weighing raw materials of 5-15 parts by weight of yam polysaccharide, 1-5 parts by weight of ophiopogonone,1-5 parts by weight of rheum emodin, 5-10 parts by weight of liposome and 10-30 parts by weight of a freeze-drying protective additive; mixing evenly the raw material components, adding the raw materials to a phosphate buffer liquid of pH = 7 for oscillation hydration to form a homogeneous solution; placing a filtrate obtained by filtering the homogeneous solution in the environment of -40 DEG C for freezing, then placing the filtrate in a room temperature environment for natural thawing, after repeating for 3 to 6 times, placing the filtrate in the environment of-40 DEG C for prefreezing for 4-8h, and then placing the filtrate in a vacuum freeze drying machine for drying to obtain the porcine epidemic diarrhea virus liposome diluent freeze-dried product. The method can reduce batch difference among semi-finished products, can promote the reproduction of porcine epidemic diarrhea virus, improves the virus content, and enhances the immunogenicity of a vaccine.
Owner:浙江美保龙生物技术有限公司

Medicine composition containing parietic acid and pharmaceutical purpose of medicine composition

The invention relates to a medicine composition containing parietic acid and a pharmaceutical purpose of the medicine composition. The composition comprises the parietic acid and rheum emodin and can also comprise chrysophanol and emodin monomethyl ether. The composition can be made into preparations in a solid form, a liquid form, a gas form or a semi-solid form. A great number of experiments prove that the medicine composition can be used for treating kidney diseases, nephrotic syndrome, hypertensive nephropathy, cardiovascular and cerebrovascular diseases, tumor diseases and the like.
Owner:XIAN SHIJISHENGKANG PHARMA IND
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