114 results about "Diethyl phosphate" patented technology

The invention discloses a preparation method of antistatic modified chinlon filaments, and relates to the field of chinlon filaments. When the antistatic modified chinlon filament is prepared, (formylmethyl) diethyl phosphate and 1-aminopyrrole react to prepare pyrrole diethyl phosphate; reacting the hydroxylated multi-walled carbon nanotube with pyrrole diethyl phosphate to obtain a modified multi-walled carbon nanotube; the preparation method comprises the following steps: reacting 2, 2 '-bipyridine-5, 5'-dicarboxylic acid with 2-amino-5-nitrophenol, and then reducing to obtain a benzoxazole diamine monomer; then, adipic acid, 1, 5-diaminopentane and a benzoxazole diamine monomer are subjected to a reaction, and modified polyamide is prepared; uniformly mixing the modified polyamide, the modified multi-walled carbon nanotubes, pyrrole, ferric trichloride and copper chloride, and performing melt spinning to obtain the antistatic modified polyamide filament. The antistatic modified chinlon filament prepared by the invention has excellent antistatic, flame-retardant, anti-aging and mechanical properties.

The invention relates to the technical field of chemical synthesis, and particularly discloses an alpha methyl beta phosphonate compound and a synthesis method thereof.The alpha methyl beta phosphonate compound is obtained by directly oxidizing the alpha position of aryl ketone into carbon positive and combining the carbon positive with diethyl phosphite anions under the alkaline condition by using hydrogen peroxide and iodine as oxidizing agents. The alpha methyl substituted beta phosphate ester compound can be generated by a one-step method. The method is suitable for synthesizing compounds of phosphoric acid (methyl, ethyl, propyl and the like) with different alkyl substitutes (methyl, ethyl, propyl and the like) at carbonyl alpha positions. According to the method, the alpha-methyl substituted beta phosphate compound can be synthesized only by using commercial cheap and easily available aryl ketone as a raw material, using hydrogen peroxide and iodine as oxidants and using diethyl hypophosphite as a phosphine source, and reacting in the DMSO solvent at 100 DEG C for 12 hours, so that the target product can be obtained, and the yield is excellent. Compared with previously reported methods, the method does not need low-temperature operation, is simple to operate, adopts a one-pot method, does not need a metal catalyst, and all raw materials are common bulk chemicals.

The present invention relates to a debondable solvent-borne pressure sensitive adhesive composition comprising a) a (meth)acrylate co-polymer formed from the monomers selected from the group consisting of ethyl (meth)acrylate, methyl acrylate, butyl (meth)acrylate, 2-ethylhexyl (meth)acrylate, 3-epoxypropyl (meth)acrylate, 2-hydroxyethyl (meth)acrylate, hydrogenated polybutadiene(meth)acrylate, glacial acrylic acid, vinyl acetate, and mixtures thereof; b) an electrolyte selected from the group consisting of 1-butyl-3-methylimidazolium bis(trifluoromethylsolfonyl)imide, 1-ethyl-3-vinylimidazolium methanesulfonate, 1-dodecyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide, tributyl(ethyl) phosphonium diethyl phosphate, trihexyltetradecylphosphonium bis(trifluoromethylsulfonyl)amide and mixtures thereof; c) a cross-linker; and d) a solvent.

The invention discloses a cool breathable fiber and a preparation method thereof, and relates to the field of fibers. When the cool-feeling breathable fiber is prepared, shell powder sequentially reacts with 3-chloropropyltrimethoxysilane, 2, 6-dihydroxy naphthol and 3, 3-diphenyl-2-propyne-1-alcohol, and functionalized shell powder is prepared; the preparation method comprises the following steps: reacting (formylmethyl) diethyl phosphate with (4-pyridyl) acetone, firstly polymerizing with dimethyl terephthalate and ethylene glycol, and then reacting with N-[4-(aminomethyl) phenyl] guanidine to prepare modified polyester; and finally, mixing the modified polyester, the functionalized shell powder and zinc acetate, and spinning to obtain the cool breathable fiber. The cool breathable fiber prepared by the invention has flame-retardant, durable and antibacterial capabilities.

The invention discloses a preparation method of an antibacterial moisture-permeable polyamide fiber and the antibacterial moisture-permeable polyamide fiber, and relates to the technical field of polyamide fibers. When the antibacterial moisture-permeable polyamide fiber is prepared, pretreated carbon nanotubes, ferric trichloride, sodium acetate trihydrate and diallyl disulfide are subjected to a microwave-assisted heating reaction, and carbon nanotube loaded nano iron sulfide is prepared; the preparation method comprises the following steps: modifying carbon nano tube loaded nano iron sulfide by using 3-aminopropyltriethoxysilane to prepare a modified carbon nano tube; mixing the modified carbon nanotubes and a nylon raw material, and performing melt spinning to obtain modified polyamide fibers; the modified polyamide fibers are modified with diethyl (3-aminopropyl) phosphate, 3-pyridylaldehyde and ethyl isocyano acetate, and flame-retardant modified polyamide fibers are prepared; and modifying the flame-retardant modified polyamide fiber with propane sultone to obtain the antibacterial moisture-permeable polyamide fiber. The prepared antibacterial moisture-permeable polyamide fiber has the advantages of being antibacterial, moisture-absorbing, antistatic, flame-retardant and high in tensile strength.

The invention discloses a reactive hot melt adhesive and a preparation method thereof, and relates to the technical field of hot melt adhesives. When the reactive hot melt adhesive is prepared, butyl acrylate, acrylic acid, methyl acrylate, allyl glycidyl ether and diethyl allyl phosphate are subjected to free radical reaction to prepare modified polyacrylate; reacting diethanol amine with acrylamide to synthesize a tertiary amino chain extender; reacting a hindered phenol monomer with pyridol, and then adding aluminum chloride for rearrangement to prepare the hindered phenol sealing agent; the preparation method comprises the following steps: reacting diisocyanate with dihydric alcohol, a tertiary amine chain extender and a coumarin chain extender, adding a hindered phenol sealing agent for blocking, adding modified polyacrylate, and mixing to obtain the reactive hot melt adhesive. The reactive hot melt adhesive prepared by the invention has the advantages of high bonding strength, self-repairing property, flame retardance and aging resistance.

The invention discloses an acid and alkali resistant fiber and a preparation method thereof, and relates to the field of fiber fabrics. When the acid and alkali resistant fiber is prepared, dimethyl terephthalate, polyethylene glycol-2000, ethylene glycol, 1, 3-bis (3-hydroxypropyl)-1, 1, 3, 3-tetramethyldisiloxane and diethyl phosphite are polymerized and then react with 4-vinyl benzoyl chloride and 2-mercaptobenzothiazole in sequence, and modified polyester is prepared; the preparation method comprises the following steps: sequentially reacting microcrystalline cellulose with 3-(chloromethyl)-2-hydroxybenzaldehyde, 4-allylthiosemicarbazide and copper chloride to prepare modified cellulose; the modified cellulose and the modified polyester are mixed and subjected to melt spinning, then perfluoroethylene is used for after-finishing, and the acid and alkali resistant fiber is prepared. The acid and alkali resistant fiber prepared by the invention has durable, flame-retardant and antibacterial capabilities.

The invention discloses a high-flame-retardant coating diaphragm for a lithium battery and a preparation method of the high-flame-retardant coating diaphragm, and belongs to the technical field of battery diaphragms. The high-flame-retardant coating diaphragm for the lithium battery comprises a base membrane and a flame-retardant slurry layer coated on the surface of the base membrane, the flame-retardant slurry comprises the following raw material components in percentage by mass: 0.2%-0.7% of a dispersing agent, 0.1%-0.5% of a wetting agent, 1%-5% of magnesium hydroxide, 5%-10% of a composite binder, 18%-22% of boehmite, 5%-10% of flame-retardant filler and the balance of ultrapure water; the flame-retardant filler is prepared from modified hollow glass microspheres and nanoscale hexagonal flaky melamine cyanurate; the modified hollow glass microspheres are obtained by modifying hollow glass microspheres with a silane coupling agent; the composite binder is obtained by compounding an acrylate copolymer and polyimide; the acrylic copolymer is obtained by grafting 1, 3-dibromopropane after acrylic acid, butyl acrylate and diethyl allyphosphate react; the polyimide is obtained by mixing and reacting beta-nicotinamide adenine dinucleotide lithium salt and biphenyl tetracarboxylic dianhydride.

The invention provides a tetraphenylethylene-based covalent organic framework material with high fluorescence quantum yield as well as a preparation method and application of the tetraphenylethylene-based covalent organic framework material. According to the material, due to the introduction of an aggregation-induced emission unit tetraphenyl ethylene, the conjugate interaction between a tetraphenyl ethylene element and a connecting group is weakened, so that the exciton kinetics among other connecting groups is changed, and the photoluminescence quantum yield is 73%; the material has a good light-emitting effect, is suitable for the field of photoelectric materials, and provides a thought for the design of similar materials. Meanwhile, the material has regular pore channels and rich active sites, the reaction activity of the imine connection site is high, phosphorus-chlorine bonds in the nerve poison stimulant diethyl chlorophosphate can be attacked in a nucleophilic mode, the conjugation relation of the connecting groups is changed, and the material has a good detection effect on the nerve poison stimulant diethyl chlorophosphate and can be used for detecting the nerve poison stimulant diethyl chlorophosphate. The method has the characteristics of simplicity and rapidness in operation, sensitive reaction, convenience in use and low cost, and can provide an effective technical means for detection of potential hazardous articles by related departments.

The invention relates to the technical field of flame retardance, and discloses a reaction type graphene flame-retardant modified polystyrene plastic, acryloyloxy diethyl phosphate of graphene and styrene are polymerized to obtain reaction type graphene grafted polystyrene, and then the reaction type graphene grafted polystyrene is compounded with impact polystyrene to obtain the reaction type graphene flame-retardant modified polystyrene plastic. The reaction type graphene flame-retardant modified polystyrene plastic is obtained, acryloyloxy diethyl phosphate bonded on the surface of graphene serves as a reaction type flame retardant and is subjected to graft polymerization with styrene, graphene and polystyrene have higher interface bonding force, compatibility of the graphene and the polystyrene is better, and the reaction type graphene flame-retardant modified polystyrene plastic is obtained. According to the present invention, the influence of the reaction type graphene on the use performance of the polystyrene is avoided, the acryloyloxy diethyl phosphate small molecules on the surface of the graphene are adopted as the phosphorus-containing flame retardant, can be decomposed during combustion to produce the phosphoric acid compound, can promote the water absorption carbonization, and can be compounded with the graphene to form the continuous carbon barrier layer so as to achieve the good synergistic flame retardation effect;

The invention discloses a method for detecting phosphate impurities, namely diethyl phosphoacetic acid and diethyl phosphate, in afatinib, and establishes a simple and sensitive ion chromatography detection method based on the hydrolysis property of a phosphate compound under an alkaline condition. Sodium hydroxide or potassium hydroxide solution-water is used as a mobile phase for isocratic or gradient elution, and a conductivity detector is used for detection. According to the present invention, the accurate quantification of the impurities in the afatinib is achieved, the detection speed is fast, the cost is low, the operation is simple, and the good specificity, the sensitivity, the precision and the accuracy are provided, such that the product quality of the afatinib maleate bulk drug synthesized by using the diethyl phosphoacetic acid as the starting material and the related preparation can be further ensured.

The invention discloses a tetrazine probe synthon and a preparation method and application thereof.The preparation method comprises the following steps that under the inert atmosphere, diethyl cyanomethylphosphonate, 3-hydroxypropionitrile, 3-mercaptopropionic acid and hydrazine hydrate are mixed and then react at the room temperature, a sodium nitrite solution is added after the reaction is finished, then acid is continuously added till the reaction system reaches acidity, and a tetrazine probe synthon product is obtained; continuously reacting to obtain an intermediate; and dissolving the intermediate in a solvent in an inert atmosphere, adding triethylamine, slowly adding methanesulfonyl chloride, and reacting at room temperature to obtain the tetrazine probe synthon shown in the formula I. The invention further discloses a preparation method of the tetrazine probe synthon. The tetrazine probe synthon provided by the invention can perform series Heck reaction and HWE reaction, so that controllable combination of functional groups on two sides of a tetrazine coupling probe is realized under mild reaction conditions, and the functional groups on two sides are designed according to actual requirements to regulate and control photophysical properties of the probe. A brand new way is provided for developing a high-performance biological orthogonal fluorescent probe.

The invention discloses a benzoxphosphine ligand and a complex and application thereof. The structure of the benzoxphosphine ligand is shown as a formula (I), in the formula (I), R1 is alkyl or aryl substituted oxazolidinyl or imidazoline, R2 is alkyl and / or aryl, and R3 is at least one of fluorine, carbazolyl and 2, 6-dimethoxyphenyl. According to the benzoxphosphine ligand disclosed by the invention, the metal iridium complex can be used as a catalyst to be applied to an asymmetric hydrogenation reaction of alpha-phenyl vinyl diethyl phosphate, and has excellent activity and relatively high enantioselectivity; moreover, the benzoxphosphine ligand disclosed by the invention can be directly synthesized from simple and easily available chiral aldehyde, and the preparation method is simple and easy to operate.

The invention relates to a waterborne polyurethane emulsion as well as a preparation method and application thereof. The preparation raw materials of the waterborne polyurethane emulsion comprise the following components: an isocyanate monomer, flame-retardant polyether polyol, polydimethylsiloxane, a hydrophilic chain extender and a small molecular alcohol chain extender. The flame-retardant polyether polyol is a polymer formed by [(bis (2-hydroxyethyl) amino) methyl] diethyl phosphate and an epoxy compound. According to the synthesized waterborne polyurethane coating, the synergistic effect of nitrogen, phosphorus and silicon is utilized, flame propagation can be effectively inhibited, the molten drop phenomenon can be remarkably inhibited, and the limit oxygen index and the vertical combustion grade of the material are greatly improved.

The invention relates to the field of IPC C07F 9 / 11, in particular to a preparation method of triethyl phosphate. Comprising the following steps: first-stage esterification; carrying out second-stage esterification; carrying out neutralization reaction; dealcoholization is performed; rectifying under reduced pressure; according to the preparation method, a segmented reaction is matched with specific post-treatment (ammonia gas introduction), so that the purity of the obtained product is more than 99.5%, the water content is controlled to be less than 0.04, the color (APHA) is less than or equal to 10, and the acid value is controlled to be less than 0.06 mgKOH / g; according to the method, the ammonia gas is added after the reaction is finished, so that dangerous substances of chloroethane are prevented from being generated by the reaction of ethanol and hydrogen chloride, the product is prevented from being decomposed into diethyl phosphate, the product yield is increased, and the residual liquid amount is reduced.

The invention provides a polymer fluorescent nano-film, a template-free self-assembly preparation method thereof and application of a nerve poison sensing detection agent, and the polymer fluorescent nano-film is prepared on a gas-liquid interface through dynamic acylhydrazone bond condensation reaction by taking a column [5] arene hydrazide derivative and tetraformyl tetraphenylethylene as film building monomers. The polymer fluorescent nano-film is prepared through template-free self-assembly, the preparation process is simple, the conditions are mild, and the accurate regulation and control of the film thickness can be realized by changing the concentration of the precursor solution or the volume of the solution per unit area. The prepared film has a flat, smooth and defect-free surface, has excellent mechanical properties, shows good toughness and puncture resistance, shows excellent sensing performance on a nerve toxic agent simulant diethyl chlorophosphate, has excellent detection capability on a real nerve toxic agent sarin under the assistance of a solvent, and can be widely applied to the field of neurology and neurology, such as neurology, neurology, neurology, neurology, neurology, neurology, neurology, neurology, neurology, neurology, neurology and neurology. The method is expected to play an important role in the fields of public place safety monitoring and the like, and has a wide application prospect.

The invention relates to the technical field of organic synthesis, and provides a preparation method of 3-methoxy-4, 5-methylenedioxy phenylethylamine. According to the invention, myristic aldehyde and diethyl cyano phosphate are adopted as initial raw materials, and the 3-methoxy-4, 5-methylenedioxy phenylethylamine is prepared through wittig reaction, reduction reaction, hydrolysis reaction and Hofmann reaction. According to the preparation method provided by the invention, each step is simple and convenient to operate, the product yield is high (the total yield is 78.3%-84.2%), and the purity is high; furthermore, the preparation method provided by the invention is mild in reaction condition, does not need explosive and highly toxic chemicals, does not need column chromatography purification of products in each step, and is suitable for industrial production.

The invention relates to the technical field of organic synthesis, and provides a synthesis method of an important organic synthesis intermediate methyl diethyl phosphonate. Comprising the following steps: firstly, adding paraformaldehyde and alkali into a solvent, heating and stirring, and filtering to obtain an intermediate solution; and adding cation exchange resin and the intermediate solution into a reaction flask, dropwise adding diethyl phosphite, carrying out a heat preservation reaction after dropwise adding is completed, filtering to remove the cation exchange resin (which can be recycled for multiple times) after the reaction is completed, and carrying out reduced pressure distillation to remove the solvent and a trace amount of diethyl phosphite residue, so as to obtain the product. The method has the main advantage that paraformaldehyde is used as a methylation reagent and reacts with diethyl phosphite in one step under the action of a catalyst to obtain a target product.

The present invention relates to a pyridine derivative-containing triarylethylene photochromic material and its preparation and application methods. A pyridine ring or its derivative containing a formaldehyde substituent at one end is subjected to a Corey-Funchs reaction to synthesize its dibromosubstituted product; then, the dibromosubstituted product is reacted with an aromatic compound or heterocyclic compound containing a boric acid or pinacol borate group through a Suzuki reaction; or a benzophenone derivative is reacted with a pyridine ring or its derivative containing a diethyl phosphate group through a Wittig reaction to obtain the pyridine derivative-containing triarylethylene photochromic material. The present invention has low-cost raw materials and a simple and easy synthesis process. The prepared photochromic material has the advantages of dual light / proton response, high color purity, a wide color change wavelength range, and long color change durability. This expands the original triarylethylene photochromic material with a single stimulus response to a light / proton dual-responsive photochromic material, and also expands the color change range from orange to red and purple. The material is suitable for multiple fields such as inspection, storage encryption, and biological imaging.

The present invention discloses a class of alkyl zinc reagents and a preparation method and application thereof, belonging to the technical field of synthetic organic chemistry. The general structural formula of the alkyl zinc reagent of the present invention is: R‑znOPiv·Mg(OPiv)Br, wherein R is selected from a chain alkyl, a cyclic alkyl or a substituted alkyl. The present invention completes the preparation of a Grignard reagent by lithium salt catalysis or iodine element catalysis, and then completes the preparation of a zinc reagent by transmetallation and an inorganic salt activation strategy to synthesize an alkyl-substituted alkyl difluoro reagent, and the general structural formula of the alkyl-substituted alkyl difluoro reagent is: #imgabs0# wherein R1 is selected from an ester group, an alkyl group, an alkynyl group, an amide, a benzoxazole, diethyl phosphate or a perfluoro-substituted alkyl group; R is selected from a chain alkyl group, a cyclic alkyl group or a substituted alkyl group; R2, R3 are independently selected from a substituted alkyl group; and R4 is selected from an ester group. The alkyl zinc reagent is applied to the bifunctional reaction of olefins, and the alkyl-substituted alkyl difluoro reagent is applied in click chemistry reactions.

The present invention relates to methods of treating endometriosis or preventing recurrence of endometriosis. In particular, the present invention relates to a method of treating endometriosis and relapse thereof, comprising administering to a woman suffering from endometriosis a pharmaceutical composition comprising an S-alkyl isothiourea derivative, in particular S-ethyl isothiourea diethyl phosphate. The methods and pharmaceutical compositions of the present invention can retain fertility and can be fertilized.

The invention relates to the technical field of cables, and provides an aerial insulated cable which sequentially comprises a wire, an insulating layer and a protective layer from inside to outside, and the protective layer is prepared from the following raw materials in parts by mass: 50-60 parts of polypropylene, 10-20 parts of polyolefin elastomer, 10-20 parts of ethylene-vinyl acetate copolymer, 20-30 parts of flame retardant and 0.5-1 part of antioxidant. The flame retardant is graphite powder coated with (4-hydroxy-phenyl)-diethyl phosphate. According to the technical scheme, the problems of poor flame retardance and low mechanical strength of the overhead insulated cable in the prior art are solved.

The invention belongs to the field of polyurethane foam plastics, particularly relates to a polyurethane foam plastic taking rice husk as a raw material and a preparation method thereof, and provides the following scheme aiming at the problem that the existing polyurethane foam plastic is relatively poor in flame retardant property. The invention discloses an environment-friendly foam board which comprises the following raw materials in parts by weight: 50-100 parts of rice husks, 1-10 parts of a foam stabilizer, 1-10 parts of a foaming agent, 50-100 parts of isocyanate, 70-90 parts of polyether and 5-10 parts of a catalyst.The rice husks are used as raw materials, can be degraded and recycled, contribute to reduction of resource waste, have the characteristic of environmental protection and good physical properties, and can be recycled, so that the environment-friendly foam board is environment-friendly and has a good application prospect. Compared with the prior art, the flame-retardant plastic has the advantages that certain use requirements can be met in the aspects of strength, heat resistance, toughness and the like, and the flame-retardant property can be greatly improved through the flame-retardant characteristics of the magnesium hydroxide, the diethyl aluminum hypophosphite, the triethyl phosphate, the dimethyl methylphosphonate, the zinc borate, the polystyrene and the polyvinyl chloride.

The invention discloses a smoke-suppressing low-toxicity flame-retardant floor board and a preparation method thereof. The method comprises the steps that S1, wood is placed in a mixed solution of imidazole diethyl phosphate and a Lewis acid catalyst, vacuum impregnation and heating and pressurizing impregnation are sequentially conducted, and the wood is drained after impregnation; the wood is sequentially placed in a chitosan solution, a metal salt solution and an alkaline solution to be subjected to pressure dipping, and complexing flame retardant modified wood is obtained after draining and washing; and S2, the complex flame retardant modified wood is soaked in a water-soluble charring agent solution, drained after being pressurized and soaked, washed with water and dried, and the flame retardant modified wood is obtained. The imidazole diethyl phosphate is obtained by carrying out condensation reaction on 1-(3-aminopropyl) imidazole and (formyl methyl) diethyl phosphate in a mass ratio of (0.5-0.7): 1. The problems that a current floor board is poor in flame retardant property durability, high in smoke density and low in carbon residue amount can be effectively solved.

The invention provides a phosphorus-nitrogen synergistic intumescent flame retardant and a preparation method and application thereof, and belongs to the technical field of flame retardants, the preparation method comprises the following steps: step S1, enabling expandable graphite and isocyanate to react in the presence of a catalyst to obtain activated expandable graphite; s2, under the protection of inert gas, 1, 3-bis (3-aminopropyl)-1, 1, 3, 3-tetramethyldisiloxane and protocatechuic aldehyde are subjected to a Schiff base reaction in a solvent, then diethyl phosphite and zinc chloride are added, a phosphoric acid addition reaction is performed, and a flame-retardant monomer is obtained; s3, adding the activated expandable graphite and a flame-retardant monomer into a solvent, and performing grafting reaction in the presence of a catalyst to obtain the phosphorus-nitrogen synergistic intumescent flame retardant. Through the process design of isocyanate activation of the expandable graphite and flame-retardant monomer grafting, a multi-component synergistic flame-retardant system based on chemical bonding is constructed, so that the flame-retardant property of the composite material is improved, and the flame-retardant durability of the composite material is enhanced.

The application discloses a liquid titanium-based polyester catalyst and a preparation method thereof, and relates to the field of titanium-based catalysts. The catalyst takes titanate as a main raw material and is prepared through modification of an ionic liquid coordination modification; the modified ionic liquid is prepared through quaternary ammonium and ion exchange reactions and is composed of imidazole cations, phosphoric acid groups and bistrifluoromethylsulfonylimide anions. The preparation method comprises the following steps: first, an intermediate chloride is prepared through quaternary ammonium reaction of N-methyl imidazole and 3-chloropropyl phosphoric acid diethyl ester; then, the modified ionic liquid is obtained through ion exchange reaction to replace anions; finally, the modified ionic liquid is subjected to coordination reaction with the titanate to prepare the liquid titanium-based polyester catalyst. The liquid titanium-based polyester catalyst prepared by the application has excellent hydrolysis resistance, catalytic activity and thermal stability performance and is suitable for the industrial production requirements of the polyester.

The application discloses a preparation method and application of a silane passivator containing diethyl phosphate groups. The preparation method comprises the following steps: heating and stirring allyl diethyl phosphate and hydrogen-containing silicone oil under an argon atmosphere; adding hydrogen-containing silicone oil, toluene and a catalyst chloroplatinic acid into the system in sequence, and heating and reacting under the Ar atmosphere; performing reduced pressure distillation until no distillate is evaporated; adding ethyl acetate into the reaction liquid for washing, and then evaporating the ethyl acetate under reduced pressure; finally, washing the reaction liquid for several times, pouring out the organic phase, and then performing reduced pressure distillation until no distillate is evaporated, so that the silane passivator containing diethyl phosphate groups is obtained. The silane passivator is stable in chemical properties and convenient to store. After the passivator is used to passivate perovskite, the ethoxy group of the passivator can endow the passivator with certain electronic transport capacity, and a phosphorus oxygen (P=O) double bond can be combined with uncoordinated lead ions (Pb 2+ ) to coordinate, so that the crystal structure is perfected, non-radiation recombination is inhibited, and the optical properties and stability of the perovskite material are effectively improved.

The invention discloses a flame-retardant gel polymer electrolyte and a preparation method and application thereof, and belongs to the technical field of supercapacitors. The method comprises the following steps: adding iodine diethyl methyl phosphate and 1, 3-propane sultone into an organic solvent containing 1, 3-dioxolane, and uniformly mixing to obtain a mixed solution; adding lithium salt into the mixed solution to obtain a precursor solution; and dropwise adding the precursor solution on the surface of an electrode to assemble a supercapacitor, and heating to form the flame-retardant gel polymer electrolyte on the surface of the electrode in situ. According to the flame-retardant gel polymer electrolyte prepared by the method, the flame-retardant characteristic of the electrolyte can be remarkably improved, the combustion risk is fundamentally eradicated, a good solid-liquid mixed interface can be formed with an electrode, and high ionic conductivity and low interface impedance are guaranteed.

This invention discloses a method for detecting genotoxic impurities in fosfomycin calcium. The method involves preparing a test solution and a reference solution using hydrochloric acid as a solvent, and then detecting the test solution and reference solution using high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS / MS) to obtain the content of genotoxic impurities in fosfomycin calcium. The genotoxic impurities are: 1,2-epoxypropyl diethyl phosphate, (2-propenyl)-diethyl phosphate, allyl diethyl phosphate, and propyl diethyl phosphate. This invention develops an analytical method capable of simultaneously detecting four diethyl phosphonate genotoxic impurities in fosfomycin calcium. This method exhibits good specificity, injection precision, linear range, limit of quantitation, limit of detection, accuracy, repeatability, intermediate precision, and robustness. It can be used for the detection and monitoring of diethyl phosphonate impurities in fosfomycin calcium raw materials, ensuring product quality and improving the safety of clinical medication.

The invention relates to a method for detecting sarin simulant diethyl chlorophosphate by using a europium-based metal organic framework nano material, and nano particles are the europium-based metal organic framework material of double ligands (1, 3, 5-tri (4-carboxyl phenyl) benzene and o-phenylenediamine tripolymer) uniformly grown on the surface of nano cellulose. The europium-based metal organic framework material taking o-phenylenediamine tripolymer as the ligand can weaken red fluorescence due to the fact that the antenna effect is hindered. Amino groups in the ligand can be subjected to nucleophilic addition reaction with diethyl chlorophosphate, so that an addition ligand with unstable coordination is generated, the addition ligand is separated from a material framework, red fluorescence is recovered, rapid and high-sensitivity fluorescence enhancement detection on sarin toxic agent simulant diethyl chlorophosphate atmosphere is realized, the detection limit is 2.88 ppb, and the response time is about 1 s. Meanwhile, the film material overcomes the interference of acid, realizes the specific detection of diethyl chlorophosphate, and provides an extensive design thought for the detection of functional metal organic framework materials and nerve toxic agents.