161 results about "Reaction intermediate" patented technology

The invention provides a hydrogen fuel cell catalyst as well as a preparation method and application thereof, and relates to the technical field of catalysts, the catalyst comprises an N atom modified carbon carrier and platinum alloy nanoparticles loaded on the surface of the carbon carrier, the platinum alloy nanoparticles are binary or multicomponent alloys formed by Pt and metal M, the molar ratio of platinum to the metal M is (0-10): 1, and the molar ratio of platinum to metal M is (0-10): 1. The weight ratio of the N atom modified carbon carrier to the platinum alloy nanoparticles is (25-80): (75-20). According to the preparation method of the hydrogen fuel cell catalyst, the N-modified carbon-supported PtFe alloy is prepared by a two-step pyrolysis method, so that the use amount of Pt is effectively reduced, the cost is controlled, and the utilization rate of Pt is increased; through the strong coordination capability of the 1, 10-phenanthroline, the formed Fe-N-C layer can restrain the growth and agglomeration of the PtFe alloy nanoparticles, the adsorption to a reaction intermediate is weakened, and the oxygen reduction activity and stability of the alloy catalyst are improved.

The present application provides a kind of for the preparation of C 3+ The application discloses a catalyst for olefin, a preparation method and application, the catalyst is supported by a molecular sieve, and the molecular sieve is MFI molecular sieve or SBA-16 molecular sieve, and the catalyst is loaded with multi-metal, and the multi-metal includes metal tungsten, transition metal and alkali metal. The catalyst is used for providing Lewis acid sites by introducing metal tungsten into MFI molecular sieve or SBA-16 molecular sieve by one-step process, and further selectively introducing transition metal and alkali metal. By selectively coupling hydrogenation-dehydrogenation sites, C-C coupling sites and alkali metal sites in the same multifunctional catalyst, the synergies between the molecular sieve carrier and the multi-metal are realized. The catalyst realizes high-efficiency ethanol-to-C 3+ Olefins conversion in ethanol, with acetaldehyde as the reaction intermediate, and has the advantages of high C 5+ Olefins selectivity.

The invention discloses a liquid metal-based catalyst with flowable amorphous cobalt active sites as well as a preparation method and application of the liquid metal-based catalyst. The spherical gallium-based liquid metal loaded amorphous cobalt nanosheet material is synthesized by using a sodium borohydride ice bath method. Due to the optimization of the synthesis process, the amorphous cobalt nanosheets are uniformly distributed on the surfaces of the liquid gallium balls, are small in size, are high in utilization rate and are not easy to agglomerate; the intrinsic flow characteristic of the liquid metal gallium realizes the efficient reverse hydrogen overflow effect, optimizes the formation process of a catalytic reaction intermediate, and accelerates the formation of the intermediate. The composite material has the advantages of low overpotential, high Faraday efficiency, high ammonia production rate, good stability and the like during nitrate electrocatalytic reduction reaction, meets the requirements of production and use, and is low in preparation cost.

According to the catalyst for generating ethylene through electrocatalytic reduction of carbon dioxide, a CuO / SrCO3 heterojunction is synthesized through high-temperature liquid-phase pyrolysis and carbonization, an energy barrier of a reaction intermediate can be optimized through the electron effect of a heterojunction interface carried by the catalyst, efficient adsorption of OCHCHgroups of the reaction intermediate is achieved, and the catalytic activity of ethylene is improved. Further proton coupling of the intermediate is promoted, and finally, a target reduction product C2H4 is efficiently generated; meanwhile, the stability of the structure is guaranteed by a stable heterojunction surface of the heterojunction, so that the heterojunction has excellent durability.

The invention relates to the technical field of preparation of electro-catalysis electrode materials, in particular to a preparation method and application of a SeO2 doped RuO2 electrolyzed water catalyst.The preparation method comprises the steps that S1, ruthenium acetate and selenium dioxide are dissolved in deionized water together and continuously stirred to obtain a mixed solution A, then sodium citrate is dissolved in deionized water, and the PH value is adjusted to be 9 with ammonia water to obtain a solution B; s2, mixing the solution A and the solution B, reacting at 80 DEG C for 12 hours, naturally cooling, ultrasonically washing with deionized water and ethanol in sequence, centrifuging, and drying in a drying oven to obtain a catalyst precursor; and S3, carrying out two-step pyrolysis on the precursor, namely heating to 250 DEG C, annealing for 4 hours, heating to 400 DEG C, annealing and heating for 2 hours, so as to obtain the SeO2-doped RuO2 nanosheet. By introducing a proper amount of SeO2 for doping, the electronic structure of RuO2 is optimized, the adsorption and desorption balance effect of the catalyst on a reaction intermediate is adjusted, the Ru site catalytic performance is improved, and the obtained SeO2-doped RuO2 nanosheet has efficient acidic OER catalytic performance.

This invention discloses a supported zirconium-based catalyst, its preparation method, and its application. It includes a zirconium-based support and a noble metal supported on the zirconium-based support. The zirconium-based support includes one or more of a zirconium-based composite oxide support and a zirconium-based metal-organic framework material. The zirconium-based composite oxide support includes a composite of zirconium oxide and other oxides, and the other oxides include oxides of one or more elements selected from Si, P, Ce, and Mg. The above-mentioned supported zirconium-based catalyst increases the interaction between the supported noble metal and the support by introducing Si, P, Ce, or Mg into the zirconium-based support to adjust the electron cloud density or oxygen vacancy concentration of the zirconium-based support. By using a zirconium-based metal-organic framework material with regular channels to support the noble metal, reactants and products can diffuse relatively quickly and smoothly, thereby avoiding excessive side reactions and carbon deposition caused by excessive retention of reaction intermediates or products.

The invention discloses a medium-entropy catalyst based on a self-reduction strategy as well as a preparation method and application of the medium-entropy catalyst, and belongs to the technical field of catalysts. The preparation method of the medium-entropy catalyst based on the self-reduction strategy comprises the following steps: jointly dissolving a non-Cu metal salt of which the metal activity is weaker than that of iron, a Cu salt, a metal coordination agent and a surfactant into water to prepare a plating solution, and immersing foam iron serving as a substrate into the plating solution for 10-60 minutes for entropy increase to obtain the medium-entropy catalyst, the molar ratio of Cu to non-Cu metal in the plating solution is (1-2): (1-4). The adsorption / desorption behavior of a reaction intermediate is optimized by cooperatively regulating an electronic structure through multiple elements, and the method has important significance for improving the performance of the NO3RR.

The application provides a regeneration method of halogenated nitrobenzene continuous hydrogenation catalyst, and relates to the technical field of fixed bed halogenated nitrobenzene hydrogenation. The regeneration method mainly comprises the following steps: using alcohol, alkali, petroleum ether and ethyl acetate to preliminarily clean the bed layer, removing azo compounds and other pollutants on the surface of the catalyst by using the special properties of ionic liquids, and then completing the regeneration of the catalyst through the steps of pickling, precious metal solution treatment and drying. The application overcomes the defects of the prior art, has the advantages of simple operation, mild conditions and low cost, realizes the in-situ removal of surface impurities such as reaction intermediates and azo compounds on the catalyst surface without damaging the structure of the catalyst and disassembling the catalyst, further supplements the lost metal active components, and can effectively restore the catalyst activity.

The invention relates to an asymmetric iridium monatomic nano enzyme Ir-S / N-C and a preparation method thereof. S atoms are introduced, an active center with an Ir-S1N3 asymmetric coordination structure is constructed, the electronic structure of the iridium active center is effectively changed, the center position of a d band of the iridium active center is moved upwards, the adsorption / desorption behavior of a reaction intermediate is optimized, a reaction energy barrier is remarkably reduced, and the reaction efficiency is improved. The activity of the oxidoid enzyme reaches 27.98 U / mg, and the activity of the peroxidase reaches 330.24 U / mg; the invention further relates to application of the asymmetric iridium monatomic nano enzyme Ir-S / N-C in preparation of a product for detecting cholinesterase. According to the detection strategy, unstable H2O2 does not need to be additionally added, the operation steps are simplified, the stability and anti-jamming capability of a system are improved, and false positive signals are effectively reduced. Experiments prove that the constructed detection method has a good linear relation and high sensitivity on detection of cholinesterase, the detection limit is as low as 0.21 U.L <-1 >, and great application potential in the fields of biomedical diagnosis and environmental monitoring is shown.

The invention provides a method and equipment for screening an electrochemical alloy oxide catalyst. Comprising the following steps: utilizing a trained machine learning model to predict the difference of second adsorption free energy of each predicted active site on the surface of an alloy oxide to be detected to an electrochemical reaction intermediate; obtaining the first average current density and the uncertainty of the current density based on the difference of the second adsorption free energy of each predicted active site; determining a pre-selected alloy oxide by using the acquisition function to obtain a second average current density of the pre-selected alloy oxide; and under the condition that the difference value between the second average current density and the obtained maximum value of the first average current density is smaller than a preset value, determining that the pre-selected alloy oxide is the target alloy oxide catalyst for the electrochemical reaction. In this way, the electrochemical alloy oxide catalyst with high electrochemical catalytic activity can be rapidly screened out.

A pseudo-boehmite has a ratio of crystalline sizes D(130) and D(020) at a ratio of D(130) / D(020)=1.0-1.5, preferably, 1.1-1.3. A preparation method of the pseudo-boehmite, a catalytic cracking catalyst containing the pseudo-boehmite, and a preparation method and application of the catalytic cracking catalyst are provided. The pseudo-boehmite is applied to a catalytic cracking catalyst, and can produce a significant mesopore distribution in case that the catalyst strength is qualified, significantly improving the pore structure of the catalyst, which is of great significance for promoting the efficient diffusion of heavy oil macromolecules, reaction intermediates and product molecules in the catalyst, reducing the coke yield, and optimizing the product distribution.

The present invention provides a process route for producing auristatin derivative intermediates, which effectively avoids the use of norephedrine in the synthesis route compared to the prior art. Furthermore, the process route for auristatin derivative intermediates according to the present invention allows for the production of the target product in a single step, effectively avoids the generation of reaction intermediates, has a simple purification method, and produces a high yield and purity of the final product, making it suitable for industrial-scale scaling up.

The invention provides a compound for an oil-based drilling fluid viscosity reducer and the oil-based drilling fluid viscosity reducer. The preparation method of the compound for the oil-based drilling fluid viscosity reducer comprises the following steps: mixing polyethylene polyamine, alcohol amine and humic acid for reaction to obtain a first reaction intermediate; and reacting the first reaction intermediate with a fluorine-containing silane coupling agent to obtain the compound for the oil-based drilling fluid viscosity reducer, wherein the ratio of the amount of substance of the humic acid to the polyethylene polyamine to the alcohol amine to the fluorine-containing silane coupling agent is 1 to (0.5 to 0.75) to (0.01 to 0.5) to (0.5 to 5). The viscosity reducer for the oil-based drilling fluid comprises the compound for the viscosity reducer for the oil-based drilling fluid, a fluorine-containing surfactant and an oil-phase solvent in a mass ratio of 100: (10-50): (20-80). The oil-based drilling fluid viscosity reducer provided by the invention has excellent high temperature resistance.

The invention provides a catalyst for preparing C3 + olefin from ethanol through a one-step method, a preparation method and application, the catalyst takes a molecular sieve as a carrier, multiple metals are loaded on the carrier, the molecular sieve is an MFI molecular sieve or an SBA-16 molecular sieve, and the multiple metals comprise metal tungsten, transition metal and alkali metal. The method comprises the following steps: introducing metal tungsten into an MFI molecular sieve or an SBA-16 molecular sieve by adopting a one-step process to provide a Lewis acid site; and transition metal and alkali metal are further selectively introduced. A hydrogenation dehydrogenation site, a C-C coupling site and an alkali metal site are selectively coupled in the same multifunctional catalyst, so that the synergistic effect between the molecular sieve carrier and multiple metals is realized. According to the catalyst, acetaldehyde is used as a reaction intermediate in ethanol conversion, efficient reaction for preparing C3 + olefin from ethanol is realized, and meanwhile, the catalyst has the advantage of high C5 + olefin selectivity.

The application discloses a kind of graphene nanometer heavy anticorrosive coating and preparation method thereof, belong to anticorrosive coating technical field.The coating includes the following mass parts of components: diallyl bisphenol A type epoxy resin 50-70 parts, histidine modifier 8-15 parts, graphene nanometer composite modified filler 12-20 parts, curing agent 5-10 parts, leveling agent 0.5-2 parts, defoaming agent 0.3-1 part.Histidine modifier is generated by 1-palmitoyl-2-oleoyl ethanolamine and N-formyl-L-histidine through Schiff base reaction intermediate A;Again with spiro ring quaternary ammonium reagent reaction forms quaternary ammonium salt intermediate B;Again with aminopropyl triethoxysilane and silicotungstate composite is obtained.Graphene nanometer composite modified filler is formed by graphene oxide / bentonite intercalation structure, by allyl trimethoxysilane surface modification.The graphene nanometer heavy anticorrosive coating prepared by the application forms high dense crosslinking network, has excellent barrier property, strong adhesion, impact resistance and long-acting anticorrosion performance.

The invention discloses a preparation method and application of a cerium-doped CoTeO3 nano-cluster catalyst, and belongs to the technical field of chemical energy materials. The preparation process comprises the following steps: firstly preparing a metal salt solution and a NaHTe solution, dropwise adding the NaHTe solution into the metal salt solution, stirring, centrifuging, cleaning and drying to obtain the cerium-doped CoTeO3 nano-cluster catalyst. The cerium-doped CoTeO3 nano-cluster catalyst prepared by the invention is constructed by a chemical reduction method, the conductivity of the catalyst is remarkably enhanced by introducing transition metal telluride, and the electronic structure of active sites is further optimized by doping rare earth cerium. In an electrocatalytic oxygen evolution reaction (OER), the catalyst breaks through the energy barrier limitation of a catalytic reaction intermediate by introducing a lattice oxygen oxidation mechanism (LOM), shows excellent catalytic activity and stability, and shows a good industrial application prospect.

Provided is a method for producing an olaparib precursor, said method comprising the step of performing the following steps (a) to (c) continuously without isolating a reaction intermediate. (a) Reacting dimethyl(3-oxo-1,3-dihydro-2-benzofuran-1-yl)phosphonate and 2-fluoro-5-formylbenzoic acid in DMF, acetonitrile, or THF and in the presence of diazabicycloundecene. (b) Reacting the reaction mixture obtained in the reaction of (a) with hydrazine. (c) Adjusting the reaction liquid obtained in the reaction of (b) to a pH of not more than 4, to obtain 2-fluoro-5-(4-oxo-3,4-dihydro-phthalazine-1-ylmethyl)-benzoic acid, which is an olaparib precursor.

Compared with the prior art, the process route for preparing the intermediate of the aurestatin derivative has the advantages that the use of norephedrine in a synthesis route is effectively avoided, in addition, the target product can be produced in one step by the process route of the intermediate of the aurestatin derivative, and the process route is suitable for industrial production. The method can effectively avoid generation of reaction intermediate products, the purification method is simple, the yield and purity of the final product are high, and the method is suitable for industrial expanded production.

The invention provides a tackifying and shear strength improving agent, a preparation method thereof and an oil-based drilling fluid containing the tackifying and shear strength improving agent. The preparation method comprises the following steps: mixing a first surfactant, montmorillonite and rectorite, and carrying out a first reaction to obtain a first reaction intermediate; mixing the first reaction intermediate with a second surfactant, and carrying out a second reaction to obtain a second reaction intermediate; mixing the second reaction intermediate with a fluorine-containing quaternary ammonium salt surfactant, and carrying out a third reaction to obtain a third reaction intermediate; and mixing the third reaction intermediate with a silane coupling agent modified nano material under an alkaline condition, and carrying out a fourth reaction to obtain the tackifying and shear strength improving agent for the oil-based drilling fluid. The obtained tackifying and shear strength improving agent is used for the oil-based drilling fluid, and has excellent tackifying and shear strength improving effects and ultrahigh temperature resistance.

The application belongs to the technical field of catalytic chemistry and porous materials, and specifically discloses a kind of vacancy anchoring full-silicon core-shell monatomic catalyst and its preparation method, the application makes Fe highly dispersed in the form of monatomic through the synergistic anchoring effect of silicon vacancy and ligand, avoids the metal oxide cluster produced by traditional impregnation method, inhibits excessive pyrolysis caused by local overheating, reduces the generation of gas impurities such as low-carbon alkane, the crystalline shell layer of the catalyst shortens the diffusion path of the product dimethyl ethylene ketone, DMK molecules can be quickly desorbed and leave the active center after generation, the content of by-product dimers is reduced, the structure of the catalyst improves the feed rate and accelerates the product diffusion, prevents the secondary reaction of reaction intermediates in the pore, greatly reduces the carbon deposition rate, forms a hydrophobic gradient layer by MTES modification, effectively repels the associated by-products isobutyric acid generated in the reaction, blocks the DMK polymerization reaction, thereby maintaining the yield of the target product DMK.

The invention belongs to the technical field of electro-catalysis, and particularly relates to a preparation method and application of a carbon dot loaded metal phthalocyanine composite material, and the specific preparation method comprises the following steps: mixing a carbon source, a nitrogen source and a metal salt, carrying out spray pyrolysis to obtain metal doped carbon dots, compounding the metal doped carbon dots and metal phthalocyanine into the carbon dot loaded metal phthalocyanine composite material, and preparing the carbon dot loaded metal phthalocyanine composite material. As a carrier, the carbon dots improve the dispersity of the metal phthalocyanine and prevent the metal phthalocyanine from being gathered, and the conductivity of the carbon dots promotes charge transfer of the metal phthalocyanine in catalysis or sensing; in addition, the electron storage and transfer capabilities of the carbon dots are combined with the redox active center of the metal phthalocyanine, so that the adsorption energy of a reaction intermediate can be optimized, and electron transfer is accelerated, thereby synergistically promoting the catalytic reaction. The preparation method is simple in process and low in cost, and the prepared composite material is regular in morphology and excellent in stability and can be effectively applied to the field of electro-catalysis, such as electro-catalysis nitric acid reduction and carbon dioxide reduction.

The invention belongs to the field of synthesis and preparation of Schiff base single crystals, and particularly relates to a p-xylylene-bis (4-amino-3-methylphenol) Schiff base single crystal and a preparation method thereof. The p-xylylene-bis (4-amino-3-methylphenol) Schiff base single crystal is a Schiff base formed by condensation of one molecule of p-phthalaldehyde and two molecules of 4-amino-3-methylphenol, and is a completely symmetrical bis-Schiff base, and the molecular structural formula of the p-xylylene-bis (4-amino-3-methylphenol) Schiff base single crystal is C22H20N2O2. The compound has good optical performance, can be used as a reaction intermediate product for synthesis of epoxy resin, and has important significance for research of high-thermal-conductivity epoxy resin; and the new single crystal can show excellent photoelectric properties, thermal stability or magnetism, and promotes the innovation of photoelectric devices or spintronics devices.

The invention discloses a trace antimony (Sb) doped palladium (Pd)-based catalytic material as well as a preparation method and application thereof, and belongs to the technical field of electrocatalytic carbon dioxide reduction. The catalytic material is prepared by taking a palladium precursor and an antimony precursor as metal sources and adding a structure-directing agent into an alkaline mixed solvent through a one-step solvent hydrothermal method. By introducing a trace amount of Sb element, the electronic structure of Pd is effectively regulated and controlled, and the adsorption behavior of a reaction intermediate is optimized, so that the performance of Pd in an electro-catalysis carbon dioxide reduction reaction is remarkably improved. An electrochemical test shows that under a neutral condition (0.5 M KHCO3), the catalytic material can improve the carbon monoxide Faraday efficiency of Pd from 40% to 80%, and shows excellent catalytic activity and good stability. The method is simple in synthesis process, mild in condition and good in repeatability, and the obtained catalytic material is controllable in structure and has a wide application prospect in the field of electrocatalytic carbon dioxide reduction.

The application discloses a lamellar nickel selenide / vanadium selenide self-supporting composite electrode of mallotus philippinensis and a preparation method and application thereof. In the preparation method, selenium powder is used as a selenium source, sodium dodecyl sulfate and polyvinylpyrrolidone are used as morphology control agents, a vanadium source and an alkali source are uniformly mixed, a nickel-vanadium-based hydroxide precursor is in-situ synthesized on a foam nickel by using a hydrothermal reaction method, selenium powder is added into the precursor, and an integrated Ni3Se2 / V5Se8 / NF self-supporting composite electrode is prepared by using a pyrolysis method. The application accelerates the redox process in the electrochemical reaction process, reduces the adsorption energy barrier of the reaction intermediate, and thus improves the catalytic performance of the material. On the other hand, the electron transfer in the electrocatalytic reaction process is improved, the catalytic activity is promoted, the strong interaction between the active material and the NF substrate can be effectively ensured, and the active material exhibits good mechanical stability and anti-deformation ability in the electrochemical application.

The invention belongs to the technical field of organic photochemical synthesis and catalysis, and discloses application of a spin catalyst based on a macrocyclic gadolinium complex in photooxidation reduction reaction. According to the spin catalyst, the high-spin ground state of gadolinium ions is utilized, intersystem crossing of a photoreaction intermediate singlet-state free radical ion pair to a triplet-state free radical ion pair is promoted through the paramagnetic effect, and the reverse electron transfer process is effectively inhibited. Particularly, in a water-containing system, the Gd-DOTP complex induces solvent water molecules to form an ordered hydrogen bond network through a phosphonic acid group on a ligand, a proton-mediated spin transmission channel is constructed, and efficient catalysis can be achieved under the millimole-level low concentration (0.53.0 mM). The system obviously inhibits BET, improves the organic photooxidation reduction reaction efficiency, is suitable for reactions such as halogenated aromatic hydrocarbon dehalogenation and benzene oxidation hydroxylation, and has the advantages of small catalyst dosage, good stability, wide application range and the like.

The application relates to the technical field of organic synthesis, and discloses a method for synthesizing 4-benzyl-5-hydroxy-1-phenyl-1-en-3-ketone compounds. In the application, silane is used as a reducing agent, organic phosphine is used as a ligand, a dibenzylideneacetone compound (I) and an aldehyde compound (II) are subjected to a conjugate reduction / aldol addition series reaction under the catalysis of Cu to obtain a 4-benzyl-5-hydroxy-1-phenyl-1-en-3-ketone compound (III). The method carries out two-step series reactions in the same reaction container, does not need to separate reaction intermediates, reduces the operation process of separation and purification, and is simple in operation. The reaction condition is mild, and the reaction can be carried out at normal temperature. The copper catalyst is a non-noble metal catalyst, and has the advantages of wide source and low price.

According to the catalyst for generating the ethyl alcohol through electro-catalysis of the carbon dioxide, a CuO / BaCO3 heterojunction with non-orthogonal stress is synthesized through liquid phase pyrolysis and carbonization, the non-orthogonal stress can reconfigure a relative energy barrier of a reaction intermediate, the adsorption strength of a * OCHCHintermediate is enhanced, and the adsorption efficiency of the * OCHCHH intermediate is improved. Promoting proton coupling electron transfer to form a * OCHintermediate, and finally directionally generating CHOH; meanwhile, due to the stable structure brought by the stable non-orthogonal stress action of the heterojunction, the excellent durability of the heterojunction is maintained.

This invention discloses a biphase heterojunction multi-shell hollow metal oxide electrocatalyst and its preparation method, belonging to the field of electrocatalyst technology. This invention utilizes transition metals chromium and ruthenium to construct a metal oxide electrocatalyst with a biphase heterostructure, effectively integrating the advantages of chromium and ruthenium. Furthermore, it optimizes the electronic structure of active sites using interfacial synergistic effects, significantly enhancing the catalyst's adsorption capacity for reaction intermediates, thereby significantly improving catalytic performance. Building upon this, glucose is further used as a raw material, combined with calcination to introduce a multi-shell hollow structure, amplifying the material's advantages. The unique hierarchical porous structure not only significantly increases the catalyst's specific surface area and exposes abundant active sites but also optimizes mass transfer efficiency, ultimately achieving breakthroughs in comprehensive performance such as low overpotential and excellent long-cycle stability.

The invention relates to the technical field of tert-butyllithium preparation, in particular to a tert-butyllithium preparation method which comprises the following steps: preparing raw materials, dissolving lithium and washing oil, mixing the raw materials to start reaction, dropwise adding a modifier, carrying out heat preservation treatment, cooling, settling and taking clear liquid. According to the method, trace impurities on the surface of lithium are removed in the pretreatment link, the PVP coating can block contact of water, oxygen and lithium in a long-acting mode, lithium is prevented from going bad in the earlier stage of storage and reaction, and meanwhile the compatibility of lithium and organic solvents such as n-pentane is enhanced; the interference of impurities on the reaction can be eliminated in a high-purity state of the chlorinated tert-butane, byproducts such as lithium tert-butoxide are prevented from being generated, the moisture in the system is strictly limited by deep dehydration, a stable anhydrous environment is provided for synthesis of the tert-butyllithium, and the reaction efficiency is guaranteed; the operation of deep dehydration and impurity removal by activated aluminum oxide creates a high-cleanliness solvent system for the reaction, avoids the action of water and polar impurities with tert-butyllithium or reaction intermediates, and prevents product decomposition or impurity generation.

This invention provides a multi-scale neighborhood synergistic catalyst, its preparation method, and its applications. The method uses nitrogen-doped carbon nanotubes (NCNTs) as a structural platform, achieving precise construction of Al diatomic sites through vapor-phase migration, trapping, and reduction fixation of volatile metal precursors. Furthermore, it combines secondary vapor-phase deposition to drive the surface deposition and nucleation of metal-containing Y species, resulting in in-situ growth into metal nanoclusters to obtain Al2-Y. NC / NCNT catalyst. In this catalyst, Al species are atomically dispersed and exhibit coordination unsaturation, while metallic Y is anchored to its neighboring interface in the form of nanoclusters. Both maintain a stable nearest-neighbor structure under the confinement and anchoring effect of carbon nanotube doping sites. The Al2 sites can regulate the selective adsorption configuration and electronic state of reaction intermediates, while the Y nanoclusters provide efficient hydrogen molecule activation and overflow hydrogen supply channels. Together, they lower the energy barrier of key hydrogenation steps and suppress excessive hydrogenation side reactions. This invention features mild conditions, a simple process, and exhibits excellent hydrogenation activity and selectivity.