6results about How to "Reduce separation and purification process" patented technology

The invention provides the immunomodulatory octapeptide, the small peptide molecule has a unique structure, high broad-spectrum antibacterial activity, strong pathogenic bacterium inhibition and high purity, the stability of the structure and the antibacterial activity can be maintained in artificial gastric juice, no obvious hemolytic activity exists, and the immunomodulatory octapeptide has a very high application value in livestock breeding. The invention also provides a preparation method and a purity detection method of the immunomodulatory octapeptide.

The application provides an arginine deiminase mutant with alkali resistance, and the amino acid sequence of the mutant is SEQ ID NO:3. When L-arginine is used as a substrate to synthesize L-citrulline, the pH value of a reaction system can be as high as pH 11 or higher, and hydrochloric acid neutralization is not needed, so that the cost of product separation and purification and waste water treatment is significantly reduced.

The invention relates to a method and a device for preparing dibutyl terephthalate through micro-reaction, which are characterized in that a mixture of terephthalic acid and n-butyl alcohol continuously passes through a tubular reactor with a built-in turbulent flow component in the absence of a catalyst at certain temperature and pressure to generate the dibutyl terephthalate. The continuous tubular reaction is adopted, through esterification reaction, the conversion rate of terephthalic acid exceeds 99.5%, the selectivity of dibutyl terephthalate exceeds 90%, and the high-purity dibutyl terephthalate is obtained by distilling the mixed product. The continuous esterification reaction of terephthalic acid can be realized, the process flow is simple, the product quality is high, and the method is suitable for industrial production.

The invention discloses a method for inhibiting a deamination side reaction in a hydrogenation process of 2, 4-diaminotoluene, and relates to the technical field of chemical production. The method comprises the following steps: adding a supported single-metal ruthenium-based heterogeneous catalyst, 2, 4-diaminotoluene, a deamination inhibitor and a reaction solvent into a reaction kettle, sealing the reaction kettle, replacing air in the kettle for three times with N2 at room temperature, starting low-speed stirring at 10-100 rpm, simultaneously introducing H2 to replace the atmosphere in the reaction kettle, dissolving a part of hydrogen, finally introducing H2 to the pressure of 2-5 MPa, controlling the temperature to be 150-200 DEG C, and reacting for 1-2 hours to obtain the 2, 4-diaminotoluene. And increasing the stirring speed to 700-1000rpm, and carrying out hydrogenation reaction for 8-15h to obtain a corresponding product. According to the method, the deamination inhibitor is adopted to inhibit the deamination side reaction in the process of preparing the HTDA by catalyzing TDA hydrogenation through the loaded single-metal ruthenium-based heterogeneous catalyst, efficient and green preparation of the target product HTDA is achieved, the selectivity of the HTDA is improved by 20%-30%, the deamination side reaction is basically avoided, the atom utilization rate of the reaction is improved, and the requirement for equipment is low.

The present invention relates to the technical field of film-forming descaling agents, and in particular to a boiler water treatment agent based on polyamines, a preparation method thereof, and a use method thereof. The raw materials for preparing the boiler water treatment agent include: polyamines and composite chelating agents, and the molar ratio is 1: (4-6). The boiler water treatment agent provided by the present invention has a wide applicable temperature and pressure range, can withstand extreme conditions of up to 600°C and 17.8MPa, has excellent film-forming performance, can form a denser and more stable protective film layer on the metal surface, and provides reliable anti-corrosion protection. The corrosion rate of carbon steel in boiler water is as low as 0.12g / (m 2 h).

The present application relates to a method and device for preparing dibutyl terephthalate by micro-reaction, which continuously passes a mixture of terephthalic acid and n-butanol through a tubular reactor with built-in turbulence components at a certain temperature and pressure in the absence of a catalyst to produce dibutyl terephthalate. The present application uses continuous tubular reaction, and the conversion rate of terephthalic acid is over 99.5% and the selectivity of dibutyl terephthalate is over 90% through esterification. High-purity dibutyl terephthalate is obtained through distillation treatment of the mixed product. The present application can realize continuous esterification of terephthalic acid, has a simple process flow, high product quality, and is suitable for industrial production.