2results about How to "Reduce separation and purification process" patented technology

The application provides an arginine deiminase mutant with alkali resistance, and the amino acid sequence of the mutant is SEQ ID NO:3. When L-arginine is used as a substrate to synthesize L-citrulline, the pH value of a reaction system can be as high as pH 11 or higher, and hydrochloric acid neutralization is not needed, so that the cost of product separation and purification and waste water treatment is significantly reduced.

The present application relates to a method and device for preparing dibutyl terephthalate by micro-reaction, which continuously passes a mixture of terephthalic acid and n-butanol through a tubular reactor with built-in turbulence components at a certain temperature and pressure in the absence of a catalyst to produce dibutyl terephthalate. The present application uses continuous tubular reaction, and the conversion rate of terephthalic acid is over 99.5% and the selectivity of dibutyl terephthalate is over 90% through esterification. High-purity dibutyl terephthalate is obtained through distillation treatment of the mixed product. The present application can realize continuous esterification of terephthalic acid, has a simple process flow, high product quality, and is suitable for industrial production.