3 results about "Dihydroarteannuin" patented technology

The invention discloses an application of artemether, artesunate or dihydroartemisinin in preparation of a medicine for preventing or treating aflatoxin B1 poisoning. Belongs to the technical field of medicine. The technical problem of detoxification of aflatoxin B1 is solved. The invention provides an application of artemether, artesunate or dihydroartemisinin in preparation of a medicine for treating aflatoxin B1 poisoning diseases. The body can be promoted to detoxify the AFB1.

The invention discloses an alkynylation dihydroartemisinic acid probe, a biotin-dihydroartemisinic acid probe and a preparation method and application of the alkynylation dihydroartemisinic acid probe. The structural formula of the alkynylated dihydroarteannuic acid is as shown in formula 1. And a'biotin-dihydroartemisinic acid 'probe structure is constructed. And co-incubating the probe and a cell lysis solution, co-incubating a lysis solution-probe mixed solution and streptavidin magnetic beads, and eluting to obtain the drug-specific binding protein. According to the invention, the action target of dihydroartemisinin in disease treatment can be quickly, simply and conveniently found.

Dihydroartemisinin (“DHA”) derivatives that contain a stereospecific C-10 ether linkage and an aryl pharmacophore moiety are disclosed. In some forms, the DHA derivatives possess anticancer properties that are comparable to or better than the parent DHA and / or an existing anticancer drug (e.g., Cisplatin), and are useful in anticancer treatments (such as ovarian cancer and colon cancer). Methods of synthesizing the DHA derivatives that are cost effective are disclosed. Methods of using the DHA derivatives for treating a cancer, such as ovarian cancer and / or colon cancer, in a subject in need thereof are also disclosed.