66results about How to "High antibacterial efficacy" patented technology

The present invention relates to compositions comprising a combination of one or more antiseptic and an antibiotic. It is based, at least in part, on the discovery that such combinations tend to deter the formation of antibiotic-resistant organisms. In preferred, nonlimiting embodiments of the invention, the antibiotic is minocycline and the antiseptic is a chlorhexidine compound, triclosan, or benzalkonium chloride, and in particular embodiments, a silver salt or a bismuth salt is added. Examples of specific, nonlimiting embodiments of the invention include combinations of (i) minocycline, triclosan, and a bismuth salt; (ii) minocycline, a chlorhexidine compound, and a bismuth salt; and (iii) minocycline, benzalkonium chloride, and a bismuth salt. The present invention further provides for articles, such as, but not limited to, medical articles, which have been treated with or which otherwise comprise a combination of antiseptic and antibiotic.

The invention discloses a veterinary suspension containing amoxicillin, colistin sulfate and prednisolone and a preparation method thereof. The veterinary suspension adopts the amoxicillin, the colistin sulfate and the prednisolone as active ingredients. The preparation method of the veterinary suspension containing the amoxicillin, the colistin sulfate and the prednisolone comprises the following steps of: (1) dissolving or dispersing a suspending agent, an antioxidant and a preservative in a hot dispersion medium to obtain a solution (A); (2) adding 40-80 percent of dispersion medium in a formula ratio in a colloid mill, starting the colloid mill, then slowly adding the solution (A) and adding a wetting agent while stirring after the solution (A) is fully added; (3) sequentially adding the amoxicillin, the colistin sulfate and the prednisolone after fully adding all the accessories, and grinding by adopting two alternate modes, i.e. an endless grinding mode and a non-endless grinding mode; and (4) detecting the grain fineness, stopping grinding when the grain fineness accords with the requirement, adding the dispersion medium to the formula ratio, mixing, canning, sealing and sterilizing to obtain the veterinary suspension containing the amoxicillin, the colistin sulfate and the prednisolone.

The invention discloses a silicon-zinc nano mesoporous inorganic antibacterial and a preparation method thereof. The preparation method comprises the following steps: stirring polyethylene glycol-polypropylene glycol-polyethylene glycol triblock copolymer, deionized water and acid together, adding a silicone source, a zinc source and a copper source, and heating to continuously stir to obtain sol-gel solution; and drying and sintering the sol-gel to obtain the silicon-zinc mesoporous material. The silicon-zinc nano mesoporous inorganic antibacterial consists of silicon dioxide and zinc oxide, and can also be added with copper oxide, wherein the silicon dioxide serves as a network support for the antibacterial; and the zinc oxide and the copper oxide serve as active bodies of the antibacterial; and mesopores prepared by the method have an ordered structure. The antibacterial has the characteristics of simple preparation method, strong bacteria resistance, durable antibacterial effect, stable bacteria resistance, no toxin to human bodies and the like, and can be widely applied to the fields such as ceramics, plastics, spinning, coatings, water treatment and the like.

The present invention discloses the new use of available antimalarial arteannuin and its derivatives dihydro arteannuin, antiannuic methyl ether, antiannuic ethyl ether and antiannuic amber. Arteannuin and its derivatives are used through combination with antibiotic medicine to inhibit bacterial growth and enhance the antibiotic effect of available antibiotic medicine. Especially, antiannuic amber is applied in preventing and treating bacterial infection diseases except being used as antimalarial.

The invention relates to multifunctional wallpaper capable of shielding Wi-Fi signals and a production method thereof. The multifunctional wallpaper comprises a base, a multifunctional layer on the base, and a pattern layer printed on the multifunctional layer. The production method of the multifunctional wallpaper includes the steps of selecting base material; preparing material of the multifunctional layer; preparing evenly-dispersed slurry; preparing uniform water-based paint; preparing the multifunctional layer; printing the multifunctional layer; producing a finished product. The multifunctional wallpaper has the functions of shielding Wi-Fi signals, conducting electricity, insulating, decreasing noise, inhibiting bacteria, preventing molds, proofing moisture and the like, human, equipment and information security can be protected, and application range of the wallpaper is widened.

The invention provides a new swine antibacterial peptide PR-39 mutant as well as a preparation method and application thereof. The new swine antibacterial peptide PR-39 mutant is obtained by carrying out space structure analysis on the amino acid sequence of swine antibacterial peptide PR-39 through biosoftware and mutating three amino acids of 39 amino acids, so that the antibacterial effect of the new swine antibacterial peptide PR-39 mutant is obviously improved. On the basis, a novel swine antibacterial peptide PR-39 mutant gene is artificially synthesized by adopting a pichia pastoris preferred codon, a new antibacterial peptide recombination yeast strain is obtained by expressing the novel swine antibacterial peptide PR-39 mutant gene by cloning into pichia pastoris, and a fermentation scale is expanded to a fermentation tank level, so that the high-density fermentation and high-efficiency expression of an antibacterial peptide product are realized. After fermentation liquor is further purified, antibacterial peptide preparations, namely powder, liquid and the like, are prepared for preventing and treating livestock and poultry diseases.

The invention discloses a luminous antibacterial aqueous inner wall coating and a preparation method and application thereof. The formula of the luminous antibacterial aqueous inner wall coating comprises the following components in part by weight: 30 to 60 parts of film-forming emulsion, 5 to 50 parts of luminous pigment, 5 to 40 parts of white pigment and filler, 0.5 to 15 parts of montmorillonoid filler, 0.1 to 5 parts of auxiliary agent and 5 to 15 parts of water. In the coating, aluminate long-afterglow luminous material subjected to surface treatment is used as the luminous pigment, pillared montmorillonite of loaded germicide quaternary phosphonium salt is used as antibacterial filler, and acrylic acid emulsion is used as base resin; and the multifunctional inner wall coating with good luminous, antibacterial and waterproof properties is obtained by adding the auxiliary agent. The coating is endowed with excellent luminous, antibacterial and mildew-proof properties based on the traditional inner wall coating; the preparation process is simple and feasible; the raw materials have low cost; and the coating can be used for large-area decoration of multiple places, combines the traditional decoration and emergency indication or weak light illumination functions, and has good industrialized value and broad application prospect.

The invention discloses a preparation method of a bi-color artificial quartz stone slate. The method comprises steps as follows: (1) raw materials are weighed in proportion and stored separately; (2)an antibacterial agent is added to resin and stirred and mixed in vacuum; pigments, a coupling agent, glass particles, artificial quartz particles, natural quartz sand and quartz powder are stirred and mixed in vacuum; finally, a curing agent is added and stirred and mixed in vacuum, and a mixture is obtained; (3) the mixture is uniformly spread on a template; (4) the template is sent into a vacuum vibration forming press for vibratory pressing forming; (5) primary curing and secondary curing are performed sequentially after vibratory pressing forming. The mechanical properties such as hardness, toughness and the like of the artificial quartz stone slate are effectively improved through optimization and improvement of a raw material formula, matching of different raw materials and improvement of the preparation method, the artificial quartz stone slate has high anti-bacterial ability and lasting anti-bacterial action, and the comprehensive performance of the artificial quartz stone slate is improved.

The invention relates to a disposable movement tooth protecting socket and a preparation method thereof. The preparation method of the disposable movement tooth protecting socket disclosed by the invention comprises purification and modification of konjac glucomannan, preparation of compound gel, degasification, molding and drying. The konjac glucomannan is taken as a carrier and assisted by other assistants; the disposable movement tooth protecting socket has excellent film-forming property, water-tightness, antibacterial property, large tensile strength, and good toughness; the konjac glucomannan is taken as a main material of the disposable movement tooth protecting socket. Compared with the existing movement tooth protecting socket, the disposable movement tooth protecting socket is high in tensile strength, and high in acid and alkali resistance, high-temperature resistance and antibacterial effect. The product is not degraded under normal use, can be completely degraded in soil under the conditions such as water, carbon dioxide, microorganisms, temperature and the like, is short in degradation time, convenient to draw materials, low in price and simple in production technology, accords with the national environment-friendly and low-carbon policy, and accords with the processing and production requirements of the disposable product. The disposable movement tooth protecting socket also has excellent performances such as antibacterial property, water resistance, breaking resistance, softness and the like.

A medicine "Sulfapyrimidine silver-crustamine" in the dosage form of powder contains sulfapyrimidine silver (0.5-2 wt. portions), crustamine (1-50) and polyvinyl alcohol (50-150). Its advantages are high stability and antibacterial effect, and high wound-healing speed.

The invention relates to body paper, in particular to antibacterial body paper. In the process of preparing the antibacterial body paper, the following components relative to the weight of oven dry stock are added: 0.05 to 0.20 percent of double alkyl quaternary ammonium salt and 0.01 to 0.10 percent of 1-hydroxy ethylidene-1,1-diphosphonic acid, wherein in the process of preparing the antibacterial body paper, a right amount of alkali can also be added, so that the pH value of the antibacterial body paper reaches 6.5 to 8.0. Compared with the prior art, the double alkyl quaternary ammonium salt is used as an antibacterial agent, the 1-hydroxy ethylidene-1,1-diphosphonic acid is used as a synergist, the pH of pulp is regulated to ensure the pH of the body paper to reach a suitable value, and then the antibacterial body paper is prepared by adopting a conventional process. The detection shows that the body paper has an excellent antibacterial effect, the bacterium secondary pollution in the production, storage and using process can be prevented and the health index of the body paper is ensured to accord with the requirement.

The invention relates to the technical field of durable ivory board processing, and concretely relates to a durable ivory board. The durable ivory board comprises raw paper and a coating layer, and the coating layer comprises, by weight, 50-80 parts of nanometer calcium carbonate, 1-5 parts of microcrystalline cellulose, 1-5 parts of silica gel powder, 25-45 parts of modified starch, 0.5-2 parts of grapefruit seed extract, 0.1-0.5 part of a dispersing agent and 1-3 parts of a defoaming agent. The invention also provides a production method of the durable ivory board. Pure natural plants are used as antibacterial components and are compounded to obtain the coating layer, and the surfaces of a surface layer and a bottom layer are coated with the coating layers, so the durable ivory board hasan antibacterial effect, is natural and pollution-free, and has no potential harm to human bodies; and the modified starch added into the coating layer has no corrosivity, improves the durability ofthe ivory board, and also improves the adhesiveness of the coating layer and the paper base.

The invention relates to a method for preparing silver-loaded chitosan medical dressing by utilizing loquat leaves or loquat kernel extract. The method comprises the following steps: extracting effective ingredients of the loquat leaves or loquat kernels by using a leaching method to obtain extract of the loquat leaves or loquat kernels; reducing silver nitrate with the extract to prepare a nano-silver aqueous solution; and finally immersing a chitosan fiber non-woven fabric with the nano-silver aqueous solution to obtain the silver-loaded chitosan medical dressing with excellent antibacterial effect. The method has the characteristics of simple process, ecological friendliness, quick action, high efficiency, safety, no toxicity and the like; the silver-loaded chitosan medical dressing prepared by treating the chitosan fiber non-woven fabric with nano-silver has excellent broad-spectrum antibacterial property and durable antibiotic efficiency, and has an antibacterial rate over 98 percent even being washed for multiple times.

The invention discloses multifunctional environmentally-friendly water-based paint. The multifunctional environmentally-friendly water-based paint comprises main materials, additives and deionized water, wherein the main materials include diatom ooze, maya blue, tourmaline, nanometer titania, ultra-fine aluminum silicate, sepiolite, silicon carbide and zinc fluosilicate; the additives include acrylate polymer emulsion, silver ion solution, fluoro-silicone emulsion, wetting dispersant, preservative, polyvinyl alcohol, a thickener, hydroxypropyl methyl cellulose, a buffering agent, a defoaming agent, an anticracking agent and inorganic pigment. The invention also discloses a preparation method of the multifunctional environmentally-friendly water-based paint. According to the multifunctional environmentally-friendly water-based paint, the raw materials are environmentally-friendly, nontoxic and pollution-free materials; maya blue, nanometer titania and diatom ooze are used in match to enable efficient function of resisting formaldehyde, ammonia and benzene; the silver ion solution and nanometer titania are used in match to enable effective antibacterial effect and long-lasting antibacterial effect; tourmaline and silicon carbide are added, so that the functions of health care, smell removing and fireproofing are realized.

The invention discloses indoor antibacterial and environment-friendly powder paint for removing formaldehyde, and the indoor antibacterial and environment-friendly powder paint comprises the following components by weight: 0.03-0.05% of nano silver, 0.3-1% of chitosan, 5-10% of pure diatom, 5-10% of anatase titanium dioxide, 30-45% of heavy calcium carbonate, 25-35% of light calcium carbonate, 15-25% of barium sulfate and balance of an assistant. The raw materials adopted by the indoor antibacterial and environment-friendly powder paint are environmentally-friendly non-toxic and pollution-free, the indoor antibacterial and environment-friendly powder paint is effectively antibacterial and durable in antibacterial effect, can automatically absorb the formaldehyde and other toxic and harmful gases in indoor air, has long lasting purification effect, may not cause secondary pollution, has the advantages of simple preparation and convenient packaging and storage, and is suitable for indoor decoration of all kinds of buildings.

The invention provides a novel hybrid antibacterial peptide CE-PR as well as a preparation method and application of the novel hybrid antibacterial peptide CE-PR. The preparation method comprises the steps of splicing 19 amino acids at the N end of an antibacterial peptide cecropin P1 and 26 amino acids at the N end of an antibacterial peptide PR-39 on the basis of spatial structural analysis on amino acid sequences of swine-derived antibacterial peptides PR-39 and cecropin P1; adding protein Lingker (GPG) in the intermediate; and carrying out mutation (K12N) on an amino acid at the position 1 in the N end of the antibacterial peptide cecropin P1 to obtain the novel hybrid antibacterial peptide CE-PR with a remarkably-improved antibacterial effect. On the basis, a pichia pastoris optimal codon is selected to artificially synthesize a novel hybrid antibacterial peptide CE-PR gene which is cloned into pichia pastoris to express to obtain a novel antibacterial peptide recombinant yeast strain, and the fermentation scale is amplified to the level of a fermentation tank, so that the high-density fermentation and efficient expression of an antibacterial peptide product are realized. After being further purified, a fermentation solution can be prepared into powder, liquid and other antibacterial peptide preparations for preventing and treating livestock and poultry diseases.

The present invention provides a pharmaceutical composition useful for treating bacterial infections in humans and animals which comprises administering to a human or animal in need thereof, an antibacterially effective combination of a β-lactam antibiotic and an inhibitor of any bacterial peptidoglycan biosynthesis enzyme, especially GlmU, GlmU, MurA, MurB, MurC, MurD, MurE, MurF, MurG, MraY, and UppS. Further provided is a method of discovering synergists for antibiotics including: a) expressing in a cell an antisense nucleic acid against a nucleic acid encoding a gene product so as to reduce the activity or amount of the gene product in the cell, thereby producing a cell sensitized to an antibiotic; b) characterizing the sensitization of the cell to the antibiotic and selecting pairs of antibiotics and genes that result in antibiotic efficacy at one-fifth or less the concentration required in the absence of the antisense gene; c) screening for chemical compounds that inhibit the gene product corresponding to the selected synergistic gene; and d) selecting or creating chemical analogs that inhibit the gene product corresponding to the selected synergistic gene such that the inhibition occurs in the bacteria.

An inflammation-relieving filming powder for injury wound contains polyvinyl pyrrolidone iodine (0.5-10 wt. portions) and water-soluble chitosan (10-300 portions). Its advantage is high healing speed.

The invention relates to the field of concrete, in particular to an antibacterial admixture for high-strength and high-performance concrete, and relates an antibacterial admixture for high-strength and high-performance concrete. The antibacterial admixture is prepared by mixing the following components in parts by mass: a polycarboxylate superplasticizer, a chitosan-copper oxide composite antibacterial agent, fly ash, hydroxypropyl methyl cellulose, bentonite and polyacrylamide. The preparation method of the antibacterial admixture for the high-strength and high-performance concrete comprisesthe step of ultrasonic blending of the polycarboxylate superplasticizer and the chitosan-copper oxide composite antibacterial agent, and further comprises the step of blending of other components, andthe preparation method is simple and convenient. Good antibacterial performance is realized, and the antibacterial effect is lasting; the admixture has good water absorption performance, and under the condition that a small dosage of the admixture is added, the strength of concrete can be greatly improved.

The invention discloses a muscular function appliance for preventing and treating early-stage dental-maxillofacial deformities. The basic structure of the muscular function appliance comprises a lip and cheek screen, upper and lower tooth eruption rails, lip thorns, a tongue ring, a tongue bracket, breathing holes, a lip ring hole and a lip ring. The appliance mainly corrects the bad maxillofacial muscular functions through the different designs of the parts to influence development of the maxilla and the mandible, the correcting concept is added into the appliance, and therefore the purpose of correcting the dental-maxillofacial deformities is achieved. According to the appliance, development of the maxilla or the mandible is stimulated by adjusting the height of the lip and cheek screen and the positions of the lip thorns according to the pathogenesis and the disease symptoms of a patient; the surface of the appliance is provided with the breathing holes and the lip ring hole (used by being matched with the lip ring), and the breathing holes and the lip ring hole are used for mouth breathing habit correcting and lip muscle training respectively; the tongue ring is mainly used for guiding a tongue body to be placed at the correct position to coordinate the relative position relation of the maxilla and the mandible. The prepared muscular function appliance is better in pertinence, more stable in treatment effect, more convenient to use and capable of meeting the requirements of orthodontics of the patient and clinical application.

The invention discloses a printing fabric production process, and relates to the technical field of textile processing. The printing fabric production process includes the working procedures of preparing base fabric, desizing and boiling, dyeing, high-temperature setting, printing, re-setting treatment and the like. The invention further discloses an antibacterial microcapsule preparation method,which realizes uniform coating of particles, lightens the agglomeration tendency easy to occur in conventional means, improves the uniformity of microcapsules, and the obtained printed fabric has a good antibacterial effect, good color fastness, uniform color, high use performance and a good market prospect.

The invention discloses antibacterial flame-retardant polyamide 66 fabric and a preparation method thereof. The preparation method of the antibacterial flame-retardant polyamide 66 comprises the following steps: (1) performing pre-polymerization reaction and polymerization reaction on a phosphorus-containing flame retardant, diamine and dihydric alcohol in water sequentially to obtain a flame retardant prepolymer; (2) adding the flame retardant prepolymer into the polymerization process of the polyamide 66 to obtain flame-retardant polyamide 66; and (3) performing antibacterial treatment on the flame-retardant polyamide 66. The antibacterial flame-retardant nylon and fiber have high antibacterial property, durable antibacterial efficacy, stable antibacterial property and high flame-retardant oxygen index, and further improves the antibacterial property and the flame retardance of the polyamide. The antibacterial flame-retardant nylon and fiber has high flame retardance, also has the antibacterial function, can be widely applied to public facilities such as seat fabric of airplanes, high-speed trains and the like, and can be applied in the fields of medical services, clothes and the like.

The invention discloses a veterinary suspension containing amoxicillin, colistin sulfate and prednisolone and a preparation method thereof. The veterinary suspension is the veterinary suspension with amoxicillin, colistin sulfate and prednisolone as active ingredients. The preparation method comprises the following steps: 1) dissolving or dispersing suspending agent, antioxidant and antiseptic in heat dispersion medium to obtain liquid A; 2) taking 40-80% of the formulation amount of dispersion medium and pouring it into a colloid mill , start the colloid mill, and then slowly add the above liquid A. After all the addition is complete, add the wetting agent while stirring; 3) After all the excipients are added completely, add amoxicillin, colistin sulfate and prednisolone in sequence, Then adopt the mode of circulating grinding and non-circulating grinding to grind; 4) check the particle fineness, stop grinding after meeting the requirements, add dispersing medium to the formula amount, mix, fill, seal, sterilize, and obtain the Veterinary suspension of penicillin, colistin sulfate and prednisolone.

The invention provides moisture-absorption polyacrylonitrile fibers, and belongs to the technical field of chemical fibers. The moisture-absorption polyacrylonitrile fibers are obtained by the following steps: hydrolyzing the polyacrylonitrile fibers by using a mixed solution containing a NaOH solution and an alkaline amino acid solution, neutralizing until the pH value is 6-7 after cooling, and then adding a crosslinking agent solution for crosslinking and cleaning, wherein the moisture regain of the prepared polyacrylonitrile fibers is greater than or equal to 3.64%, and is higher than 375.26% of that of non-hydrophilic modified acrylic fibers. According to the preparation method disclosed by the invention, the carboxyl group in basic amino acid can be connected with acrylic fibers and Al3 + together in a subsequent crosslinking process, the main chain amino group and the side chain basic group of the basic amino acid are kept, the water solubility and the electropositivity of the acrylic fibers are improved, the acrylic fibers are endowed with certain antibacterial activity and lasting property, the color, the shape and the mechanical property of the polyacrylonitrile fibers canbe well kept, and the prepared polyacrylonitrile fibers have lasting antibacterial property, good morphology and mechanical property.

The invention relates to a preparation method of a disposable sweat-absorbing antibacterial glove. The method comprises steeping fluid preparation, degassing, steeping and bonding, drying, secondary steeping and bonding, secondary drying and demolding. Konjac glucomannan is taken as a carrier and other aids are added, so that the disposable sweat-absorbing antibacterial glove has the advantages of excellent film forming property, moisture retention, hydroscopic property, bacterinertness, high tensile strength and high flexibility; the konjac glucomannan is taken as a main material of the disposable environmentally-friendly glove, so that the glove has the advantages of high tensile strength, good wearing effect, high antibacterial efficiency and capability of keeping hands clean and sanitary during long-time operation; the glove can be biologically degraded completely, is environmentally-friendly, and has low carbon content; the glove is hydroscopic and humectant, so that skin is keptin a dry state, and folded skin and hand adhesion caused by palm sweating due to long-time wearing of the glove are avoided; the glove is nontoxic, harmless and resistant to high temperatures, and does not cause the toxin transfer phenomenon of other material gloves such as a PVC (Poly Vinyl Chloride) glove and the like due to direct contact with foods or high-temperature foods; a production process is simple, materials are readily-available, and price is low; and the glove has a certain retention effect on additive pigments.