7results about How to "Synergistic" patented technology

The present invention relates to a composition of aliphatic emulsion preparation for malignant thoracicoabdominal hydrops and its preparation method. It is made up by adopting pure natural anticancer medicine elemene and at least one polysaccharide selected from ginseng polysaccharide, astragalus polysaccharide, acanthopanax polysaccharide and lyceum polysaccharide as raw material. Said invention can obviously raise solubility of medicine, increase stability of medicine, effectively remove and kill cancer cells and raise immunity of body.

This invention belongs to the field of material surface treatment technology, specifically relating to a wafer polishing slurry, its preparation method, and its application. The wafer polishing slurry comprises abrasives, oxidants, dispersants, surfactants, pH adjusters, and water. The components of the wafer polishing slurry work synergistically, shortening polishing time and improving polishing efficiency when applied to wafer polishing. Furthermore, it significantly improves the surface quality of the polished wafer, markedly reducing scratches and defects, and lowering surface roughness to below 0.15 nm, thus meeting the surface quality requirements of fields such as power electronics and radio frequency devices.

The application discloses application of chrysin in preparation of a medicine for treating primary Sjogren's syndrome and belongs to the technical field of biological medicine. The application proves that chrysin can be specifically combined with TNFR2 protein and is a new type of TNFR2 inhibitor through molecular docking, molecular dynamics simulation, CETSA experiment and SPR experiment. Animal experiments show that chrysin can significantly increase the secretion amount of saliva and tear of a mouse model of primary Sjogren's syndrome, reduce the serum SSA and SSB antibody levels, reduce lymphocyte infiltration and acinus atrophy of submandibular glands and lacrimal glands, inhibit the expression of a cytokine INF-gamma, and the drug efficacy is equivalent to that of a positive medicine hydroxychloroquine; chrysin and gaoshunyujin have a synergistic effect, and the improvement effect on primary Sjogren's syndrome is better than that of hydroxychloroquine. The application provides a new medical use of chrysin, and provides a safe and effective prevention and treatment medicine for primary Sjogren's syndrome.

The invention belongs to the technical field of medicines, and particularly relates to a pharmaceutical composition for treating pancreatic cancer and a preparation method thereof. The pharmaceutical composition comprises an annonaceous acetogenin derivative and cimicifugin in a mass ratio of 1: (0.3-0.5). The annonaceous acetogenin derivative is prepared through three-step reaction of hydrolysis, oxidative bromination and condensation, and has remarkable OGT enzyme inhibitory activity. After the annonaceous acetogenin derivative and the cimicifugin are combined according to a specific mass ratio, the in-vitro proliferation inhibition effect on pancreatic cancer cells and the tumor inhibition effect in an animal model of the annonaceous acetogenin derivative and the cimicifugin are remarkably better than those of a single drug and an original drug, and the annonaceous acetogenin derivative and the cimicifugin have a good synergistic interaction characteristic; in addition, the composition can obviously reduce the toxicity to normal cells, and provides a new drug selection and combined treatment strategy for pancreatic cancer treatment.

This invention discloses a black hot spring bath concentrate, its preparation method, and its application, relating to the field of personal care products technology. It comprises component A, an active black hot spring concentrate, and component C, a sulfide and humic acid composite stabilization system. Component A must contain humic acid with a content of ≥500 mg / L metasilicic acid, 5-15 mg / L fluoride ions, ≥10 mg / L total hydrogen sulfide, ≥20 mg / L metaboric acid, and ≥100 mg / L total organic carbon. Component C consists of selenite, polyphenolic antioxidants, and metal ion chelating agents. This invention utilizes a low-temperature membrane enrichment-bioenzymatic hydrolysis coupling-nano-stabilization integrated technology to fully preserve the quaternary characteristic component spectrum of black hot springs ("metasilicic acid-fluoride-sulfide-humic acid"), and uniquely employs a composite stabilization technology targeting the dual-active system of "sulfide-humic acid." It can be stored for a long time at room temperature and pressure, exhibiting excellent physical stability and long-lasting efficacy, and demonstrating a clearly targeted therapeutic effect of black hot springs.

This invention relates to the field of wastewater treatment technology, specifically disclosing a photoanode material, a photoanode, its preparation method, and its application in wastewater treatment. The photoanode material comprises an FeSe2 array layer and a Bi2O2WO4 layer supported on the FeSe2 array layer. FeSe2 has a narrow band gap, good light absorption performance, and photogenerated charge separation capability, which can sensitize other semiconductors with wider band gaps to form heterojunctions, promoting the improvement of photocurrent density and electron quantum yield, and enhancing the photoelectric conversion efficiency of the catalytic material. Bi2O2WO4 is composed of [Bi2O2]. 2+ Layers and [WO4] 2‑ The vertically alternating layers facilitate the separation of photogenerated electrons and holes, thereby enhancing the catalytic oxidation activity of the electrode. The combination of Bi₂O₂WO₄ and FeSe₂ improves their respective solar photoresponse capabilities and photoelectrocatalytic performance, offering significant advantages in environmental engineering.

This invention provides a compound herbicide, its preparation method, and its application, relating to the field of pesticide technology. The compound herbicide provided by this invention combines metolachlor or butachlor, nicosulfuron, and propyzoxystrobin or propyzoxystrobin. Through extensive experiments, the inventors discovered that these herbicides, with their different mechanisms of action and weed-killing spectra, not only have a synergistic effect when combined, but also broaden the weed-killing spectrum. Furthermore, all three have short residual periods, do not affect subsequent crops, and facilitate crop rotation. Under different formulations, it can be used in sorghum fields, sunflower fields, corn fields, potato fields, rice fields, etc., adding new agents and options for weed control, reducing pesticide application rates, and promoting sustainable agricultural development.