60 results about "Amygdalin" patented technology

The invention discloses a determination method of a UPLC fingerprint spectrum of children heat-clearing and cough-relieving granules, and belongs to the technical field of pharmaceutical analysis. According to the invention, the children's heat-clearing and cough-relieving granules are subjected to UPLC chromatographic analysis, and a UPLC fingerprint spectrum containing 16 common characteristic peaks including ephedrine hydrochloride, pseudoephedrine hydrochloride, amygdalin, liquiritin, baicalin and baicalein is established, so that the overall quality of the children's heat-clearing and cough-relieving granules can be evaluated more comprehensively; a new technical thought is provided for quality control and quality evaluation of the heat-clearing and cough-relieving granules for children.

The invention provides a method for detecting medicinal components of a traditional Chinese medicine composition UPLC-MS / MS. The detection method can be used for identifying 14 medicinal components of the traditional Chinese medicine composition, namely saikoside A, saikoside D, naringin, paeoniflorin, hesperidin, chicoric acid, chlorogenic acid, salvianolic acid B, narcissoside, kaempferitrin, lobetyolin, amygdalin, hyperoside and rutin. And a reference is provided for evaluating the internal quality of the traditional Chinese medicine composition.

The invention discloses a preparation method and antipyretic and anti-inflammatory application of a novel carrier-free metal-organic small molecule supramolecular hydrogel derived from Maxing Shigan Decoction. The hydrogel drug raw materials of the invention include pseudoephedrine hydrochloride in Ephedra sinica in the prescription of Maxing Shigan Decoction, amygdalin in Armeniaca vulgaris, magnesium ions in Gypsum fibrosum, and glycyrrhizic acid in Glycyrrhiza uralensis Fisch. The preparation method of the quaternary magnesium hydrogel drug is simple, green, has good stability and high biocompatibility. In a rat fever model induced by lipopolysaccharide at different doses, the antipyretic effect of the hydrogel drug can last up to 12 hours, and the antipyretic effect is significantly better than that of other metal ions such as quaternary calcium hydrogel, quaternary zinc hydrogel, and quaternary copper hydrogel groups. At the same time, it has a more persistent antipyretic effect than the whole prescription of Maxing Shigan Decoction; the hydrogel drug does not require the addition of excipients, has no toxic and side effects, and has a high drug utilization rate.

The invention discloses wine peach kernel decoction pieces and a preparation method thereof, and the method comprises the following steps: adding 10-20% by mass of yellow wine into peeled and cleaned peach kernels, uniformly stirring, and moistening at room temperature for 20-40 minutes to enable the yellow wine to be soaked and absorbed; and placing the moistened peach kernels in a drum-type herbal medicine roaster, frying at 100-140 DEG C for 10-20 minutes until the water content is 3-12%, and cooling to obtain the wine peach kernel decoction pieces with wine aroma. The wine peach kernel decoction pieces prepared by the method disclosed by the invention have the extract content of 21-31% and the amygdalin content of 2.4-3.6%, and are suitable for large-scale stable production.

The invention discloses an establishment method of an HPLC (high performance liquid chromatography) characteristic chromatogram of granules for treating common cold and clearing heat and a component content test thereof, and belongs to the technical field of pharmaceutical analys.According to the research, the HPLC characteristic chromatogram of the granules for treating common cold and clearing heat is established under the same chromatographic condition by adopting a high performance liquid chromatography, and the overall internal quality in a preparation is comprehensively reflected; the method for simultaneously determining the content of amygdalin, puerarin, cimicifugin and corydalis bungeana is established, methodology verifies that the method is simple, convenient and feasible, has good stability and repeatability, and can be used for detection in production process monitoring and quality evaluation of the cold and heat clearing granules to ensure that the quality of the cold and heat clearing granules meets the standard. The scheme not only scientifically restores the overall pharmacodynamic material basis of the compound preparation, but also provides a new generalizable normal form for quality control of traditional Chinese medicines with the advantages of low cost and high efficiency, and has milestone significance for promoting industry standardization and internationalization.

The invention relates to a traditional Chinese medicine composition which comprises more than 1.09 permillage of ephedrine hydrochloride, more than 0.86 permillage of pseudoephedrine hydrochloride, more than 0.17 permillage of peiminine, more than 0.03 permillage of peimine, more than 0.17 permillage of chrysin-7-O-glucuronide, more than 0.002 permillage of glycyrrhetinic acid, more than 11.87 permillage of amygdalin and more than 0.01 permillage of neotuberostemonine. The oral liquid is prepared from more than 2.16 per mill of glycyrrhizic acid, more than 1.97 per mill of oroxylin A, more than 1.97 per mill of oroxylin B, more than 1.23 per mill of liquiritin, more than 0.59 per mill of apiose liquiritin, more than 0.55 per mill of baicalin, more than 0.23 per mill of chlorogenic acid, more than 0.18 per mill of praeruptorin A, more than 0.15 per mill of wild melanosin, more than 0.14 per mill of methyephedrine hydrochloride, more than 0.13 per mill of isoliquiritin, more than 0.13 per mill of neochlorogenic acid and more than 0.13 per mill of cryptochlorogenic acid. The composition is prepared from more than 0.10% of peimine, more than 0.08% of baicalein, more than 0.05% of praeruptorin B, more than 0.04% of praeruptorin C, more than 0.011% of xanthoxylin and more than 0.0006% of formononetin.

The invention discloses a method for determining the content of forsythin and amygdalin in Sangju cold granules through high performance liquid chromatography. The method comprises the following steps: preparing a methanol contrast solution of phillyrin (30 [mu] g / ml) and amygdalin (0.1 mg / ml), taking about 2g of Sangju cold granules, adding 25ml of methanol, carrying out ultrasonic treatment for 15-60 minutes, filtering, and taking the subsequent filtrate as a sample solution; high performance liquid chromatography is adopted, phillyrin uses a C18 column, amygdalin uses a Phenyl column, the flow rate is 1 ml / min, and the column temperature is 30 DEG C. Injecting 10 microliters of solutions into a chromatographic instrument, recording peak areas, and calculating the content by using an external standard method. The method has the advantages of high sensitivity, good separation effect, strong repeatability and the like, and can provide technical support for improving the quality standard of the mulberry leaf and chrysanthemum cold granules.

The invention discloses a method for preparing D-ulcerasin from D-amygdalin. The method comprises the following steps: (1) preparing a D-amygdalin solution and a beta-glucosidase solution; and (2) mixing the D-amygdalin solution and the beta-glucosidase solution, and carrying out an enzymatic reaction under certain conditions to obtain a reaction solution containing D-aronia melanocarpa glycoside. By optimizing the preparation method, the purity of the finally prepared and purified D-ultigenin is larger than or equal to 98%, and isomers are identified through chromatography and nuclear magnetic resonance spectroscopy. The research of the experiment provides a certain possibility for the research on the pharmacological and pharmacodynamic activity, toxicity, pharmacokinetics and the like of the D-aronia melanocarpa, and also provides a certain reference significance for the research on the quality standard of medicinal materials and preparations containing amygdalin.

The invention discloses an astragaloside-salvianolic acid B-paeoniflorin-amygdalin nano-liposome and a preparation method of the astragaloside-salvianolic acid B-paeoniflorin-amygdalin nano-liposome. The mass ratio of astragaloside to salvianolic acid B to paeoniflorin to amygdalin in the nano-liposome is (1-5): (1-5); (1-10): (1-5). The liposome disclosed by the invention can be used for preparing the medicine for preventing and / or treating cardiovascular diseases, especially for preparing the astragalus-dragon gum, and has a remarkable effect in the aspect of treating cardiovascular diseases.

The application provides a preparation method of a semi-solid pure loquat whole fruit wine, comprising separation of loquat pulp and loquat kernel, loquat pulp beating, loquat kernel processing, mixing, fermentation and distillation. The application makes full use of rich carbon sources such as starch in loquat kernel and the amygdalin component with the effect of relieving cough, utilizes the aroma and nutrition of loquat fresh fruit, and absorbs the medicinal active components of loquat whole fruit. The semi-solid fermentation mode is adopted to produce the loquat whole fruit wine containing the antioxidant and cough-relieving medicinal active components, realizes efficient and high-value utilization of loquat resources, and the produced loquat whole fruit wine has a high yield and a unique loquat fragrance.

The application discloses a method for lime-free and acid-free copper-sulfur flotation separation, wherein a combined inhibitor for copper-sulfur separation comprises ferrous sulfate and amygdalin, and is used as a pyrite inhibitor in flotation separation of chalcopyrite and pyrite.The combined inhibitor ferrous sulfate and amygdalin, a collector and a foaming agent are added to a raw ore after crushing and grinding to perform a copper flotation operation, and after the copper flotation operation, a combined activator sodium percarbonate and copper sulfate, a combined collector and a foaming agent are added to the ore pulp to perform a sulfur flotation operation.The combined inhibitor ferrous sulfate and amygdalin has a strong inhibiting effect on pyrite, and can effectively realize flotation of chalcopyrite; the combined activator sodium percarbonate and copper sulfate has a good de-inhibiting and activating effect on pyrite, and can effectively realize flotation of pyrite, thereby reducing the mineral processing cost while enhancing the copper-sulfur separation effect, and having a good application prospect.

The application provides a comprehensive extraction method of effective components in peach kernel, and the prepared peach kernel powder is subjected to first extraction treatment for 2-4 times; first extraction liquid obtained by each first extraction treatment is combined to obtain crude peach kernel oil, and first solid obtained by the last first extraction treatment is taken as residue; the crude peach kernel oil is sequentially subjected to washing and liquid separation to obtain peach kernel oil and water phase; the water phase is sequentially subjected to first concentration, standing, filtration and recrystallization to obtain amygdalin; the residue is mixed with water and subjected to second extraction treatment for 2-4 times; second extraction liquid obtained by each second extraction treatment is combined and sequentially subjected to second pH adjustment and centrifugal separation to obtain crude protein, and then subjected to alkaline hydrolysis to obtain amino acid compounds. The method provided by the application improves the utilization rate of peach kernel, is easy to operate, has mild conditions, is convenient for post-treatment and has low cost.

The invention belongs to the technical field of medicines, and provides a blood-activating, swelling-eliminating and pain-relieving pharmaceutical composition containing spirolactone and amygdalin and application of the blood-activating, swelling-eliminating and pain-relieving pharmaceutical composition. The pharmaceutical composition is prepared from spirolactone and amygdalin as raw materials according to a certain weight percentage. Experimental results show that the pharmaceutical composition disclosed by the invention has a remarkable synergistic effect in the aspect of pain threshold of mice painful by a hot plate, in the aspect of mouse ear swelling degree caused by xylene and in the aspect of mouse abdominal cavity capillary permeability caused by acetic acid, has no toxic or side effect and has a relatively good clinical application prospect.

The invention discloses a method for preparing L-amygdalin and L-ulcerasin from D-amygdalin, which comprises the following steps: (1) preparing a D-amygdalin solution, and incubating the D-amygdalin solution under certain conditions to obtain an isomerization solution; and (2) preparing a beta-glucosidase solution, mixing the isomerization solution with the beta-glucosidase solution, and carrying out an enzymatic reaction under certain conditions to obtain a reaction solution containing L-amygdalin and L-ulcerasin. According to the invention, the L-amygdalin is converted from D-amygdalin through SN1 nucleophilic substitution reaction, and it is innovatively found that the L-amygdalin and the L-aronia melanocarpa glycoside are prepared and purified through asymmetric catalytic reaction according to the fact that two pairs of isomers have different selectivity to biological enzyme in space.

The invention provides temperature-sensitive degradable gel for treating intrauterine adhesion and a preparation method thereof, and belongs to the technical field of gel. The preparation method comprises the following steps: preparing an amygdalin-loaded polymer; preparing hydroxyproline modified chitosan; and mixing to prepare the temperature-sensitive degradable gel. Soybean protein isolate and carboxymethyl konjac glucomannan are prepared into solutions, then amygdalin is added into the soybean protein isolate solution, then the mixture is mixed with the carboxymethyl konjac glucomannan solution for electrostatic self-assembly polymerization to form a carrier with a three-dimensional macromolecular structure, the amygdalin is loaded, and the amygdalin / carboxymethyl konjac glucomannan composite material is obtained. After the amygdalin-loaded polymer is added into the gel, the deformation resistance of the gel can be enhanced, so that the effect of improving the supporting force of the gel is achieved, and the recurrence rate of intrauterine adhesion is reduced.

This invention belongs to the technical field of qualitative determination of ephedra, licorice, and bitter almond in traditional Chinese medicine compound preparations. This invention discloses a method for simultaneously identifying ephedra, licorice, and bitter almond in Ma Xing Shi Gan oral liquid. The test sample is placed in a Soxhlet extractor and treated with reagents of different properties to prepare a fractional extraction solution. Ephedra and licorice reference materials are then processed to obtain a reference material solution. Amygdalin reference standard is prepared by adding methanol to prepare a reference solution. The above test sample solution, reference material solution, and reference solution are used in a thin-layer chromatography system to simultaneously identify ephedra, licorice, and bitter almond. The results show that the chromatographic spots are well separated and clear, with no interference from the negative control. This method has simple pretreatment, is environmentally friendly, has high sensitivity, and its repeatability and robustness meet the requirements of the Chinese Veterinary Pharmacopoeia, thus enabling better quality control of Ma Xing Shi Gan oral liquid.

The present invention provides a method for detecting the content of anti-inflammatory active ingredients in a rhubarb and peony preparation. The method utilizes specific solvents and chromatographic conditions, and employs multi-wavelength switching technology to simultaneously and quantitatively detect nine anti-inflammatory active ingredients in rhubarb and peony granules. The method is simple to operate, has good stability, high accuracy, short detection time, high efficiency, and low detection cost. The method calculates the content of the main active ingredients in the rhubarb and peony preparation, including gallic acid, amygdalin, paeoniflorin, paeonol, aloe-emodin, rhein, emodin, chrysophanol, and physcion, by calculating the relative correction factor f. This method provides a more comprehensive method for quality control of rhubarb and peony preparations.

The goal is to artificially ripen unripe green plums in a short period of time, thereby providing plums that are equivalent in quality to naturally ripened, fully mature plums. [Solution] In the decomposition step S4, the decomposition of cyanogenic glycosides such as amygdalin contained in the pulp of raw plums promotes the production of hydrogen cyanide and benzaldehyde. In the detoxification step S5, the produced hydrogen cyanide and benzaldehyde are detoxified. In the high-temperature sterilization step S7, the detoxified plums are sterilized at high temperature. In the ultraviolet irradiation step S8, the plums are further ripened by ultraviolet irradiation. As a result, unripe green plums can be artificially ripened in a short period of time, such as a few days, and plums equivalent to naturally ripened yellow plums that mature over about a month can be obtained.

The application discloses a mandelonitrile-degrading bacterium SYY40 and a culture method and application thereof, relates to the technical field of microbial pollution degradation and environmental pollution, and provides the mandelonitrile-degrading bacterium SYY40 which is identified as Pseudomonas sp. SYY40 and named Pseudomonas sp. SYY40, and is preserved in the China General Microbiological Culture Collection Center on May 19, 2025, and the preservation number of the strain is CGMCC NO. 34596. The strain can realize efficient removal of mandelonitrile, and the degradation rate of the mandelonitrile reaches 100% within 48 hours.

The invention relates to a synthetic flora for degrading amygdalin and application of the synthetic flora in relieving amygdalin stress of peach trees. Through rhizosphere microorganism screening and functional verification, a strain, namely Sinomonas A7, which is enriched under the stress of mandelate in peach seedlings and has efficient degradation capability is identified, and the strain, Pristia megaterium C8 and Caballaria turbo P16 jointly form a synthetic flora with a synergistic effect. Experimental results show that the synthetic flora can effectively relieve the amygdalin-mediated autotoxicity effect of the plants, enhance the tolerance of the plants to stress and promote growth. The invention provides a technical route of the multifunctional complex microbial inoculant, and the multifunctional complex microbial inoculant has potential application values of removing autotoxic substances and improving crop resistance and productivity, and is suitable for rhizosphere improvement and health management of peach tree seedlings.

The present invention belongs to the field of pharmaceutical technology, and particularly relates to a pharmaceutical composition for treating pneumonia and its application, especially a pharmaceutical composition for pediatric pneumonia. The pharmaceutical composition contains active ingredients arctiin and trichosanthesdiol, and the weight ratio of arctiin to trichosanthesdiol is 2.5-7.5:1; the pharmaceutical composition may also contain the active ingredient amygdalin. Pharmacological experiments show that the pharmaceutical composition of the present invention can significantly reduce the expression levels of IL-6 and IL-1β inflammatory factors, greatly improve the treatment effect of pediatric pneumonia, and the effect is significantly better than that of arctiin, trichosanthesdiol, and amygdalin used alone at the same dose. This indicates that after combining arctiin and trichosanthesdiol, or after combining arctiin, trichosanthesdiol, and amygdalin, there is a significant synergistic effect.

The invention provides a quality detection method of bulbus fritillariae cirrhosae lung-heat-clearing syrup. According to the quality detection method, the contents of amygdalin, sipeimine, liquiritin and platycodin in the bulbus fritillariae cirrhosae lung-heat-clearing syrup are detected by adopting an HPLC-ELSD (High Performance Liquid Chromatography-Evaporative Light Scattering Detector) chromatography. According to the method disclosed by the invention, the contents of four components, namely amygdalin, sipeimine, liquiritin and platycodin D, in the bulbus fritillariae cirrhosae lung-heat-clearing syrup are determined by adopting an HPLC-ELSD method, so that the quality of the bulbus fritillariae cirrhosae lung-heat-clearing syrup can be relatively rapidly evaluated, and reference is expected to be provided for quality control of a preparation. According to the method, interference of strong ultraviolet absorption substances is effectively avoided, the research cost is reduced, the operation process is simplified, an economic and efficient analysis means is provided for determining the content of saponin compounds, and meanwhile, a reference is provided for formulating a quality control standard of the bulbus fritillariae cirrhosae lung-heat-clearing syrup.

The invention belongs to the technical field of quality detection of traditional Chinese medicines, and particularly relates to a specific chromatogram establishment and detection method of a compound Haqing injection. The method for establishing the characteristic spectrum comprises the following steps: a, preparing a reference substance solution, namely precisely weighing an amygdalin reference substance, a calycosin-7-glucoside reference substance and a praeruptorin A reference substance, and adding methanol for dissolving to obtain the reference substance solution; b, preparation of a test solution: precisely measuring the compound Haqing injection, and preparing the test solution by adopting a solid-phase extraction instrument; and c, measuring: respectively measuring the test solution and the reference solution, injecting into a liquid chromatograph, and recording a chromatogram to obtain a characteristic spectrum formed by 10 common characteristic peaks. The method is stable, high in precision and good in reproducibility, a rapid and comprehensive detection means is provided for quality control of the compound Haqing injection, and a scientific experimental basis is provided for research of a quality evaluation system of the compound Haqing injection.

The invention discloses a gene related to synthesis of amygdalin from crop seed endosperm and application of the gene, and belongs to the technical field of gene engineering. According to the invention, gene sequences of CYP79D16, CYP71AN24, UGT94AF3 and UGT94AF2 are optimized, CYP79D16 and CYP71AN24 are connected by using a linker peptide I to obtain a fusion gene I, and the fusion gene I is fused with a breeding crop endosperm strong expression promoter to construct a gene expression cassette I; connecting UGT94AF3 and UGT94AF2 by using a connecting peptide II to obtain a fusion gene II, and fusing the fusion gene II with a breeding crop endosperm strong expression promoter to construct a gene expression cassette II; transferring the gene expression cassette into an expression vector to construct a recombinant vector, and introducing the recombinant vector into a plant to obtain a transgenic crop. According to the invention, synthesis of amygdalin in crop seed endosperm is realized, the storability of crop seeds is improved, and the product can be used as a raw material for producing amygdalin, and has guiding significance and production application value for crop breeding.

The invention provides a traditional Chinese medicine composition and a preparation method and application thereof.The traditional Chinese medicine monomer composition in the traditional Chinese medicine composition comprises amygdalin-usnic acid-beta-sitosterol which is derived from traditional Chinese medicine bitter apricot kernel, pericarpium citri reticulatae and rhizoma pinelliae preparata in a compatible combination mode, all the components have a synergistic effect, and through apparent indexes, the traditional Chinese medicine composition can be used for preparing the traditional Chinese medicine composition. The traditional Chinese medicine monomer composition and the traditional Chinese medicine compatibility combination thereof are used for evaluating and investigating the effect of the traditional Chinese medicine monomer composition and the traditional Chinese medicine compatibility combination thereof on inhibiting acute bronchitis of mice according to indexes such as acute bronchitis, tissue pathological observation, inflammatory factors and sputum dilution, the acute bronchitis treatment effect is remarkable, the medical application of the traditional Chinese medicine monomer composition is expanded, the traditional Chinese medicine compatibility combination is optimized, and the traditional Chinese medicine composition has a good application prospect in treatment of bronchitis. Especially, a new treatment idea is provided for treatment of acute bronchitis.

The present invention belongs to the technical field of effective ingredient detection in veterinary drugs, and specifically relates to a method for detecting multiple main components in Baima oral liquid and its application. The method comprises: pre-treating a sample to be tested to obtain a test solution, and detecting the test solution based on UPLC-PDA. The present invention is based on ultra-high performance liquid chromatography to simultaneously detect five alkalis (matrine, oxymatrine, ephedrine hydrochloride, pseudoephedrine hydrochloride, berberine hydrochloride) and amygdalin in Baima oral liquid. The method is fast, sensitive, accurate, and highly specific. Through one-time sample processing, the above six main components are simultaneously detected and analyzed by liquid chromatography, which not only effectively saves reagents and time, but also improves work efficiency, which is beneficial to the quality monitoring of Baima oral liquid, and therefore has good practical application value.

The invention discloses a amygdalin degrading bacterium SYY40 and a culture method and application thereof, and relates to the technical field of microbial pollution degradation and environmental pollution, the amygdalin degrading bacterium SYY40 provided by the invention is identified as pseudomonas, is named as Pseudomonas sp.SYY40, is preserved in China General Microbiological Culture Collection Center on May 19, 2025, and has the preservation number of CGMCC NO.9687. The amygdalin degrading bacterium SYY40 has the preservation number of CGMCC NO.9687. The amygdalin degrading bacterium SYY40 has the preservation number of CGMCC NO.9687. The preservation number of the strain is CGMCC (China General Microbiological Culture Collection Center) The strain can realize high-efficiency removal of the mandelic acid, and the degradation rate of the mandelic acid to the mandelic acid within 48 hours reaches 100%.

The invention discloses a method for detecting effective components of a cervicitis treatment composition, which adopts high performance liquid chromatography for detection, and the chromatographic conditions are as follows: a chromatographic column is a C18 chromatographic column; the detection wavelength is 207 nm; a mobile phase A is a 0.2% phosphoric acid aqueous solution, a mobile phase B is acetonitrile, gradient elution is adopted, the mobile phase proportion is volume percent, and the elution procedure is as follows: 0-5 min, the mobile phase A is 100%, and the mobile phase B is 0%; the mobile phase A accounts for 100%-96% and the mobile phase B accounts for 0%-4% in 5-40 min; 40-60 min, the mobile phase A is 88%-58%, and the mobile phase B is 12%-42%; the mobile phase A accounts for 92% and the mobile phase B accounts for 8% in 60-80 min. The method disclosed by the invention can be used for simultaneously determining the components such as sophocarpidine, sophoridine, oxymatrine and amygdalin in the cervicitis composition, is convenient to operate, accurate in detection result and good in stability, and has very high practicability.

The invention discloses a liquid chromatography method for rapidly determining D / L-amygdalin in traditional Chinese medicine semen armeniacae amarae / semen persicae. A chromatographic column stationary phase used in the method is a silica gel matrix bonded biphenyl reversed-phase chromatography filler; wherein the type of the silica gel substrate comprises full-porous silica gel, core-shell surface porous silica gel and hybrid silica gel; the bonded chemical functional group is a biphenyl group. According to the method, silica gel substrate bonded biphenyl reversed-phase chromatographic packing is adopted as a chromatographic column stationary phase, and optimal chromatographic column temperature, mobile phase type, flow velocity, elution method and the like are combined, so that the D / L-amygdalin in the traditional Chinese medicine semen armeniacae amarae / semen persicae is rapidly measured; according to the present invention, with the method, the baseline separation of the D / L-amygdalin in the sample can be achieved within the short analysis time, the good separation selectivity on the two epimers of the D / L-amygdalin is provided, the universality is provided, and the method can be simultaneously suitable for the determination of the D / L-amygdalin in the traditional Chinese medicine semen armeniacae amarae and the semen persicae.

The invention discloses an amygdalin / glycyrrhizic acid self-assembled hydrogel and a preparation method and application thereof, and the preparation method comprises the following steps: mixing an amygdalin solution and glycyrrhizic acid, uniformly dispersing, and standing to obtain the amygdalin / glycyrrhizic acid self-assembled hydrogel; the concentration of the amygdalin solution is 0.015 to 0.040 g / mL, and the concentration of the glycyrrhizic acid in the amygdalin / glycyrrhizic acid self-assembled hydrogel is 0.015 to 0.040 g / mL. The micro-morphology of the amygdalin / glycyrrhizic acid self-assembled hydrogel is of a three-dimensional porous network structure, the amygdalin / glycyrrhizic acid self-assembled hydrogel can be used for preparing drugs for relieving or treating inflammatory encephalopathy, neuronal damage encephalopathy, blood-brain barrier damage diseases and complement activation diseases, and the amygdalin / glycyrrhizic acid self-assembled hydrogel is simple and safe to prepare and aims at complement activation inhibition.