6 results about "Acute bronchitis" patented technology

Apparatuses, systems and methods are provided for treating pulmonary tissues via delivery of energy, generally characterized by high voltage pulses, to target tissue using a pulmonary tissue modification system (e.g., an energy delivery catheter system). Example pulmonary tissues include, without limitation, the epithelium (the goblet cells, ciliated pseudostratified columnar epithelial cells, and basal cells), lamina propria, submucosa, submucosal glands, basement membrane, smooth muscle, cartilage, nerves, pathogens resident near or within the tissue, or a combination of any of these. The system may be used to treat a variety of pulmonary diseases or disorders such as or associated with COPD (e.g., chronic bronchitis, emphysema), asthma, interstitial pulmonary fibrosis, cystic fibrosis, bronchiectasis, primary ciliary dyskinesia (PCD), acute bronchitis and / or other pulmonary diseases or disorders.

Provided are a Hedera helix extract, a preparation method therefor, and use thereof. The preparation method comprises extracting Hedera helix leaves with 75%-85% ethanol, concentrating, adjusting the pH value to 9.5-11, standing, filtering to obtain a crude extract, passing the crude extract through a chromatographic column, and eluting with 60%-80% ethanol to prepare the Hedera helix extract. The chromatographic column is an HPD100 macroporous resin column, a polyamide column or a C18 column. The Hedera helix extract can be used for preparing drugs with anti-inflammatory, expectorant, and antitussive effects, as well as for treating acute bronchitis.

The invention relates to a firewood-huang heat-clearing granule as well as a preparation method and application thereof. The radix bupleuri and rhizoma anemarrhenae heat-clearing granules are prepared from 8-25 parts of radix bupleuri, 6-20 parts of rhizoma anemarrhenae, 8-25 parts of radix scutellariae, 8-25 parts of folium isatidis, 8-25 parts of mint and 20-50 parts of rhizoma phragmitis, and the preparation method comprises the steps of raw material pretreatment, alcohol extraction, concentration and drying, granulation and the like. The traditional Chinese medicine composition is suitable for diseases such as pneumonia, acute bronchitis, epidemic cerebrospinal meningitis, epidemic encephalitis B, gastrointestinal type cold and the like. Animal experiments prove that the granule has a remarkable antipyretic effect, is exact in curative effect, good in safety and good in stability, and has important clinical application value.

The invention discloses a children Maxingshigan mixture, which relates to the technical field of traditional Chinese medicine pharmacy, and has the technical key points that the children Maxingshigan mixture is prepared into an oral liquid dosage form by mixing ephedra, bitter apricot kernel, gypsum, liquorice, folium isatidis, houttuynia cordata, trichosanthes peel and scutellaria baicalensis according to a specific weight ratio and adding auxiliary materials. The preparation method comprises the following steps: pretreating the raw materials, decocting and extracting twice, merging filtrate, refrigerating and finely filtering, concentrating in vacuum, preparing liquid to a constant volume, filtering and filling at a terminal, sterilizing and the like. The mixture disclosed by the invention has the effects of diffusing lung, depressing qi, clearing heat and eliminating phlegm, is mainly used for treating heat cough and asthma syndromes caused by exogenous evil entering the interior and transforming heat in children, and is particularly suitable for patients with acute bronchitis with the syndromes. The dosage form is convenient for children to take, stable in quality and exact in curative effect.

The invention provides an application of exosomes secreted by autologous stem cell culture in bronchitis COPD treatment, based on an autologous adipose-derived stem cell (ADSCs) organ-like cell directional culture technology, stem cells are induced to be differentiated into bronchial organ-like cells, the exosomes secreted by the bronchial organ-like cells are collected, and the COPD treatment of bronchitis is realized. Through atomization administration, chronic bronchitis, acute bronchitis and chronic bronchitis can be treated. The exosome of the tissue cells of the autologous bronchial mucosa directly reaches the bronchial mucosa through aerosol inhalation, and plays a role through the following ways: anti-inflammation: inhibiting an NF-kappa B pathway, and reducing the release of IL-6 and TNF-alpha; epithelium repair: activating a Wnt / beta-catenin signal to promote basal cell proliferation and enhance a mucus cilia removal function; immunoregulation: regulating and controlling polarization of macrophages to M2 anti-inflammatory phenotype. Therefore, local concentration is high, whole-body side effects are avoided, the whole path of trachea-bronchus-alveolus alveolus is covered, and precise targeted repair is achieved.

A hederasaponin composition and a hedera leaf extract. The hederasaponin composition comprises hederasaponin C, α-hederasaponin, hederasaponin B, and hederasaponin D in a mass ratio of 12-25:5-10:1:1-2. The hederasaponin composition and the hedera leaf extract can be used for preparing drugs for treating or preventing acute bronchitis, expectorants, and antitussives.