116 results about "Expectorant" patented technology

The present invention relates to a sustained release oral pharmaceutical tablet formulation containing an expectorant and a decongestant.

A mixed-release tablet or capsule formulation including vehicles for the delivery of a plurality of drugs in various combinations of immediate release, extended release, and/or delayed release modes over a predetermined time period have been developed, which provide for controlled release not just of the drugs, but controlled release that is designed to create more effective coordination between the drugs being delivered. The drugs can be any medically and/or physiologically appropriate combination of drugs and active ingredients, preferably decongestant drugs, antihistamines, expectorants, antitussives, cough suppressants, and drying agents.

Methods and devices for treating excess mucus accumulation in mammals by administering gaseous inhaled nitric oxide or nitric oxide releasing compounds as a mucolytic agent or expectorant are provided. Delivery of gaseous nitric oxide can be made nasally or orally and is preferably substantially coincident with inhalation of the mammal or based on a synchronous parameter of the mammal's respiratory cycle. Varying therapeutic profiles may be used for the delivery of gaseous nitric oxide depending on the severity of the excess mucus accumulation. Parameters for the therapeutic profiles may include flow rate of nitric oxide containing gas, duration of administration of nitric oxide containing gas, number of breaths for which nitric oxide containing gas is to be administered, and concentrations of therapeutic NO delivered to the airways.

Compositions and methods can be used for tolerizing the immune system. The compositions can be physiologically acceptable and can include any of a wide variety of allergens that are designed to be administered in escalating doses to, for example, an infant. The compositions can include other active ingredients (e.g., one or more of a steroid, vitamin, mineral, vasodilator, hormone, decongestant, anticholinergic agent, leukotriene inhibitor, immunomodulator, mast cell stabilizer, expectorant, immune suppressant, anti-histamine, or anti-inflammatory agent) and/or a carrier.

The present invention relates to compositions comprising an antitussive, a decongestant and an expectorant, and in a specific embodiment comprising hydrocodone, phenylephrine hydrochloride and guaifenesin, wherein the composition may be substantially free of added sugar and added alcohol, and methods for using these compositions for the treatment of patients suffering from, for example and without limitation, coughing, sneezing, rhinorrhea, and/or nasal obstruction.

The invention provides a process for preparing Fudosteine, which has the chemical structural formula (I) disclosed in the specification. The Fudosteine can be used as the medicament for relieving cough and expectorant.

The present invention relates to compositions that comprise an expectorant, an extended release antitussive, and an extended release decongestant, in liquid. Specifically, the compositions may comprise guaifenesin, and the tannate salts of phenylephrine and dextromethorphan. The present invention also includes methods for using these compositions for treatment of patients suffering from, for example and without limitation, coughing, sneezing, rhinorrhea, and/or nasal obstruction.

The invention relates to a vitex oil nanoemulsion and a preparation method and application thereof. The preparation method is characterized in that the advanced nanotechnology is used for the formula and process design of the vitex oil nanoemulsion. The preparation method comprises the steps that: vitex oil, medium chain fatty acid triglyceride, soy lecithin, ethanol and the like are evenly mixed to be used as an oil phase; poloxamer is mixed with water and the like to be used as a water phase; the oil phase is added to the water phase to be mixed and emulsified at a temperature of 40 to 60 DEG C and be treated by a two-step high-pressure homogenizer to obtain the milk-white vitex oil nanoemulsion with the average particle size of less than 100nm. The vitex oil nanoemulsion prepared by the invention has high quality, reliable quality stability and good biocompatibility, and simultaneously has good expectorant, antitussive and antiasthmatic effects.

The present invention discloses the use of Fritillaria fricarifolia alkaloid compounds represented by general formula I in the preparation of antitussive, expectorant and/or anti-inflammatory drugs, wherein R1 is: =O or R2 is: H; R3 is: H; R4 is H or OH; R5 is: O or none. Among them, Sibetine, Tribenidone, Sibetine Nitrogen Oxides, Isofibesine, Isofibesine Nitrogen Oxides and 10 times the amount of codeine phosphate have similar antitussive effects, and the 5 The antitussive and anti-inflammatory effects of this monomer are also superior to peiminine and peiminine; among them, peiminine, peiminine, sibenetine, sibemine nitrogen oxide, and isobeamine Nitrogen oxides have a good expectorant effect. The invention also discloses the total alkaloid extract of Fritillaria wabu and its preparation method and application. Formula I

The invention discloses a composition for treating chicken mycoplasma respiratory infection and a preparing method of the composition. The composition comprises, by weight, 1-10% of erythromycin thiocyanate, 40-90% of ammonium chloride and the balance anhydrous dextrose. According to the composition, the erythromycin thiocyanate is used as a main ingredient for resisting mycoplasmas, is effective in various mycoplasmas causing the chicken respiratory infection, is taken orally and can be absorbed, and can effectively treat mycoplasma infection of respiratory tracts; the ammonium chloride is an expectorant and enables sputum to be discharged easily through increase of sputum quantity, thereby facilitating removal of phlegm, enabling cheesy material and phlegm in tracheas to be diluted, dissolved and discharged out of the body, and keeping smooth breath. Through combination of the two medicines, the composition aims at pathogeny and also aims at symptomatic treatment, can effectively improve the cure rate, and reduces losses caused by respiratory disease characteristics.

The invention discloses an apophlegmatic and antasthmatic tea, which is made of 2% to 4% of coltsfoot flower, 8% to 16% of dahurian rhododendron leaf, 5% to 8% of guangdong earthworm, 5% to 8% of Aster tataricus tatarian aster, and 5% to 8% oftea leaf. The preparation process comprises the steps of selecting the blending materials according to said proportion, mixing, cleaning, crushing, drying, filling the nonwoven-fabrics inner bag with the blending materials, filling the aluminum foil outer bag with the inner bag, and hot pressing and sealing.

A formulation for oral administration comprises an expectorant, an analgesic, and at least one additional active ingredient having a modified release providing a therapeutic effect for each of the active ingredients for up to 12 hours.

The invention relates to a method for preparing an expectorant, namely ambroxol key intermediate trans-4-[(2-amino benzyl) amino]-cyclohexanol. Nitrobenzaldehyde and trans-4-amino cyclohexanol are subjected to the combination reaction of condensation, carbon and nitrogen double-bond hydrogenation and nitro reduction to prepare the trans-4-[(2-amino benzyl) amino]-cyclohexanol in a high-yield mode. The method has the advantages of reasonable process route design, simple and convenient process, high reaction yield, low raw material cost and no harsh reaction conditions and is easy for scale production.

The acetylcysteine has always been widely used as expectorant in clinic in domestic, with the using form being spray (powder spray) and effervescence tablet, the invention relates to a method for preparing the powder injection of acetylcysteine (comprising freeze-drying injection, dissolvent crystalline powder, un-dissolvent crystalline powder, etc) and large fluid infusion and its clinical application, the powder injection of acetylcysteine can not only be used in form of injection and spray for removing the phlegm, but most importantly it can be used in form of injection for treating various hepatitis, especially the light or heavy chromic, acute hepatitis B, and etc.

Capsule preparations are produced by using solutions for capsule-filling which contain ibuprofen, polyethylene glycol, water and terpenes (menthol, limonene, borneol, dl-camphor, mentha oil, etc.) optionally together with one or more drugs selected from among antipyretic analgesics, antihistamines, antitussives, expectorants, sympathetic stimulant, analeptics, hypnotic sedatives and anti-inflammatory agents, solubilizers, thickeners, pH controlling agents, colorants, etc. Thus, it is attempted to relieve the bitterness of ibuprofen and establish an immediate action at the same time.

The present invention relates to extended release formulations comprising expectorant. More particularly, the present invention relates to extended release formulations comprising guaifenesin. The present invention also relates to a process for the preparation of extended release formulations comprising guaifenesin.

A green bamboo health-care drink and a preparation method thereof, characterized by comprising the following dry raw materials: 70-90 parts of green bamboo leaves, 4-15 parts of hericium erinaceus or dictyophora phalloidea, 5-10 parts of chrysanthemum or grass jelly, and appropriate amount of sugar and purified water. Conventional microwave extraction method and\or compound enzyme digestion method, or such conventional extraction methods as hot water extraction method or ethanol extraction method; total flavonoid or other effective active materials are extracted from green bamboo leaves. The finished products can be green bamboo juice health-care drinks and green bamboo leaf flavone oral liquid drinks. The green bamboo health-care drink has all-round nutrition, can eliminate many kinds of active oxyradical, prevents nitrosation reaction and has the functions of protecting blood vessel of brain, fatigue, ageing and bacterial resistance, anti-inflammation, antiviral, decreasing triglyceride, relieving cough and expectorant, and heat-clearing and detoxifying material.

An expectorant in the form of dripping pill is prepared from polygala root. It is based on the polygala syrup.