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148 results about "Respiratory Mucosa" patented technology

The mucous membrane lining the RESPIRATORY TRACT, including the NASAL CAVITY; the LARYNX; the TRACHEA; and the BRONCHI tree. The respiratory mucosa consists of various types of epithelial cells ranging from ciliated columnar to simple squamous, mucous GOBLET CELLS, and glands containing both mucous and serous cells.

Intelligent sputum suction device

ActiveCN106039428ARealize suction operationHigh quality suctionRespiratorsIntravenous devicesMedicineSuction equipment
The invention relates to an intelligent sputum suction device, which comprises a sputum suction detection warning device, a sputum suction action operation arm, a center controller, a sputum suction tube clean replacing box, a sputum suction and collection device and a sputum suction tube, wherein the sputum suction detection warning device is used for detecting and judging whether the sputum suction is needed or not; the sputum suction action operation arm clamps, pulls and feeds the sputum suction tube, and is provided with a pressure sensor used for detecting the tube feeding resistance; a clean sputum suction tube and a waste sputum suction tube are placed in different regions in the sputum suction tube clean replacing box; a sputum collecting bottle is arranged in the sputum suction and collection device; an infrared ray detector is configured for analyzing sucked sputum; and a central controller receives various detection signals, controls the actions of forward pushing, backward retreating, rotating and the like of the sputum suction tube, and controls the starting and the stopping of the negative pressure pump. The intelligent sputum suction device has the advantages that the sputum suction operation can be effectively realized; the sputum suction position is not limited in the front section of an artificial airway; the deep sputum suction can be effectively realized; the condition of infection risk increase due to mutual pollution of the sputum of a patient and sputum suction equipment is effectively avoided; and the injury on the respiratory tract mucosa of the patient caused by sputum suction operation is reduced.
Owner:崇好科技有限公司

Respiratory-tract magnetic-resonance spray contrast agent and preparation method thereof

The invention provides a respiratory-tract magnetic-resonance spray contrast agent, which is a gadolinium-lipid compound formed from a gadolinium contrast agent and a lipid, wherein the average diameter of the compound is less than 1,000 nm, and the mean value of the Zeta potential of the compound is more than 40 mv. The lipid component is selected from at least one or combination of phospholipids, glycolipids, sterol, cationic lipids, surfactant, amphiphilic polymers, and at least contains a positive-charge lipid component. The invention also provides a method for preparing the respiratory-tract magnetic-resonance spray contrast agent. After the contrast agent is atomized and inhaled, gadolinium is effectively distributed on the surface of far-end respiratory-tract mucosa by utilizing theelectrostatic interaction between positive charges carried by the compound and negative charges on the surface of the respiratory-tract mucosa, and the distribution uniformity of spray drips on the surface of the mucosa by means of the action of the surface activity of the lipid, so that the problem that the gadolinium is only distributed on near-end respiratory tracts, is easy to gather and flows to the lower parts of the respiratory tracts after gadolinium aqueous solution is sprayed is solved, and the surface of the whole respiratory-tract mucosa is completely and clearly shown.
Owner:RENJI HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

High performance biodegradation type metal machining protection liquid

The invention discloses high performance biodegradation type metal machining protection liquid, which is composed of high polymer carboxylic acid, organic amine, higher alcohol, a surfactant, plant oil or synthetic lubrication grease, pure water, an antifoaming agent and preservative or bacteriacide. The high performance biodegradation type metal machining protection liquid is good in biodegradable performance. A formula of the high performance biodegradation type metal machining protection liquid can be designed by choosing the plant oil or synthetic ester and other additives. Biochemical oxygen demand (BOD) / chemical oxygen demand (COD) of 3.3% of diluent is larger than or equal to 1.0, so that the high performance biodegradation type metal machining protection liquid is excellent in lubrication performance. The frictional factor mu of the 3.3% of diluent is smaller than or equal to 0.03, and tapping torque of the 3.3% of diluent is smaller than or equal to 400N*cm, so that the high performance biodegradation type metal machining protection liquid is safe, hygienic and reliable in quality. The biological median lethal dose LD50 of the high performance biodegradation type metal machining protection liquid is larger than or equal to 5,000mg/kg, the medical lethal concentration LC50 is larger than or equal to 5,000mg/m<3>, respiratory tract mucous membrane irritation is smaller than or equal to 1 level, and the high performance biodegradation type metal machining protection liquid is friendly to human and environment.
Owner:SHANGHAI YUSHIRO CHEM IND +1

Incense-fumigating oil of rhizoma atractylodis and folium artemisiae argyi

The invention discloses incense-fumigating oil of rhizoma atractylodis and folium artemisiae argyi and relates to a natural plant medicament for external use. The incense-fumigating oil disclosed by the invention is composed of the following botanical medicinal materials in percentage by weight: 80-120 g of rhizoma atractylodis, 80-120 g of folium artemisiae argyi, 40-80 g of agastache rugosus, 40-80 g of herba eupatorii, 40-80 g of clove, 40-80 g of pepper, 40-80 g of amomum cardamomum, 40-80 g of herba elsholtziae, 40-80 g of rhizoma acori graminei, and 20-80 g of rhizoma kaempferiae. The incense-fumigating oil disclosed by the invention is an aromatic oily substance, and taken by way of being inhaled through a nasal cavity, so that the local medicament concentration of a nidus is much higher than that of the whole body, therefore, the incense-fumigating oil can directly act on the nidus part and then quickly kill pathogenic microorganisms; then, the incense-fumigating oil also can enter the blood to regulate the immune system, thereby improving the local sIgA (Immune Gloulin) content of the respiratory tract, protecting the integrity of local respiratory mucosa, and promoting the synthesis and secretion of sIgA. The incense-fumigating oil disclosed by the invention can be used as a preparation which is convenient to use, safe and effective, and has an effect of strengthening the local mucosal immune function, and enhances the mucosa which is the first defense line of the body.
Owner:云南中宜本草生物科技有限公司

Sputum suction device

The invention relates to the field of medical devices, in particular to a sputum suction device which comprises a machine body, a sputum storage bottle, an air filter, a negative pressure pump, a vacuum meter for detecting negative pressure value, a vacuum pump, a silencer, a negative pressure adjusting valve, a dual-station reversing valve, a three-way valve, an oxygen pipe, a sputum suction pipe and a trachea sleeve. The silencer is connected with an exhaust opening of the vacuum pump. The air filter is connected with an air suction opening of the vacuum pump. The air filter, the sputum storage bottle, the negative pressure adjusting valve, the dual-station reversing valve and the three-way valve are sequentially connected in series from left to right. Disinfectant is contained in the sputum storage bottle. The trachea sleeve is connected with the outlet end of the three-way valve through the oxygen pipe. The sputum suction pipe does not need to be manually pulled out, the damage to the respiratory mucosa of a patient by insufficient personal experience or misoperation can be avoided, the trachea sleeve can be well fixed in a trachea through an inner air bag so that disengagement can be prevented, and through the combination of an outer air bag and a medicine applying pipe, medicine applying and sputum suction at the position of the air bags can be achieved.
Owner:葛海

Colonization probiotic preparation and application and medicines thereof

ActiveCN106890197AIncreased chance of stickingSolve the technical bottleneck that is difficult to colonize in the respiratory mucosa under the removal of the cilia transport systemNervous disorderPharmaceutical delivery mechanismAllergic dermatitisDisease
The invention relates to the technical field of biology and discloses a colonization probiotic preparation and application and medicines thereof. The colonization probiotic preparation is used for directly acting on the respiratory mucosa and comprises a surfactant and probiotics. By the surfactant, modification of a sol layer and a gel layer of respiratory tract mucus is realized, probability and speed in contact of the probiotics with respiratory mucosa cells are increased, cell surface hydrophobicity of the probiotics is changed, an adhesion rate of the probiotics and respiratory mucosa epithelial cells is increased, and accordingly the technical bottleneck of difficulty in colonization of the probiotics to the respiratory mucosa under expelling action of a mucociliary transmission system is solved. The colonization probiotic preparation can be applied to fields of preparation of medicines for treatment of rhinitis, treatment of asthma, treatment of allergic dermatitis or treatment of cranial nerve diseases, anti-nasopharynx-cancer, anti-lung-cancer or anti-cold medicines or medicines for prevention or treatment of respiratory infectious diseases.
Owner:邵萍

Multifunctional medical breathing heat and moisture exchanger

The invention discloses a multifunctional medical breathing heat and moisture exchanger. The multifunctional medical breathing heat and moisture exchanger comprises a breathing machine air inlet, a breathing machine extension pipe connector, a plurality of fixed bulges, an air particle filtering material, a heat preservation and moisture retention macromolecule material, a liquid outlet cover, a sputum secretion collecting cavity, two stretchable hoses, a liquid outlet and a filtering cavity, wherein the breathing machine air inlet is connected to the filtering cavity through the stretchable hoses; the fixed bulges are arranged in the filtering cavity; the air particle filtering material and the heat preservation and moisture retention macromolecule material are respectively arranged in the filtering cavity through the fixed bulges; the rear end of the filtering cavity is connected to the front end of the sputum secretion collecting cavity; the rear end of the sputum secretion collecting cavity is connected to the breathing machine extension pipe connector through the stretchable hoses; the liquid outlet is formed in the sputum secretion collecting cavity; the liquid outlet cover covers the liquid outlet. The multifunctional medical breathing heat and moisture exchanger has an effect of filtering air particles and can realize a constant-temperature moisture retention effect so as to protect normal exertion of functions of cilia and glands of respiratory mucosa.
Owner:郭方达

Method of medicine administration for respiratory tract

The present invention relates to a method of medicine administration for respiratory tract and an apparatus for continuous medicine administration for respiratory tract. The present invention mainly utilize a respiratory tract medicine-administrated apparatus, which includes a medicine-storing chamber, which may be attached with an opening for filling in medicine, a medicine-administrated mechanism, which is connected to the medicine-storing chamber, and a medicine-exiting port, which is connected to the medicine-administrated mechanism. The medicine-administrated mechanism includes a pusher, an air intake, and a medicine-mixing chamber. In the most front end of the medicine-exiting port, there is an arrangement of nose-inserting portion of medicine-inhaling hole with opening shape. The interior of medicine-storing chamber may be filled with powder-like medicine, and a pusher with handgrip is inserted into one side portion of the medicine-storing chamber. The medicine-mixing chamber is connected to the pusher's trough. On the upper portion of the medicine-mixing chamber, there is an arrangement of air intake for introducing air. Wherein, the medicine storing chamber is already added with powder-like medicine, and the medicine is also dropped into the medicine-retrieving portion of the pusher, after the pusher is pushed back, the medicine will drop into the medicine-mixing chamber for proceeding mixing. By inserting the nose-inserting portion into the nostril and inhaled, the medicine is mixed with air, inhaled into the nostril through the medicine-inhaling hole, entering into human body, and adhered to the mucous membrane of the respiratory tract for effectively developing the effect of the medicine. With the respiratory tract medicine-administrated method of the present invention, the medicine will be directly inhaled into the respiratory tract and adhered onto the mucous membrane to optimize the treatment for the diseases of respiratory tract.
Owner:CHANG SHIH HO

Adjustable reinforced tracheal catheter

InactiveCN102824676AAdjust soft and hardEasy to controlTracheal tubesTracheal tubeCatheter
The invention discloses an adjustable reinforced tracheal catheter which belongs to the field of medical apparatus and instruments. The tracheal catheter comprises a soft catheter, a inflating pipe, a catheter wire and a spiral steel wire rope, wherein the soft catheter is opened at the front end and is hollow; the catheter wire is arranged in the inner cavity of the catheter; the spiral steel wire rope is arranged on the inner wall of the catheter and is used for supporting; a sleeve bag is arranged at the part close to the front end part of the catheter; the rear end of the catheter is connected with a flexible rod sleeve which is internally provided with a telescopic rod and a telescopic spring, and the telescopic rod is connected with the catheter wire and can move in the telescopic rod sleeve; and a catheter body is provided with an inflating cavity communicated with the inflating pipe. According to the adjustable reinforced tracheal catheter, the problem of unsmooth ventilation caused by the factor that a soft catheter is folded by extrusion is solved on the basis of the prior art, respiratory mucosa is not hurt, the flexibility maintenance of the front end of the catheter can be enhanced, and the operating efficiency and control force of a user on the catheter are greatly improved by cooperation of the telescopic rod and the telescopic spring.
Owner:NANJING SHUANGWEI BIOTECH

Mucosal vaccine composition

The present invention aims at providing a vaccine composition capable of being administered to an intraoral mucous membrane, ocular mucous membrane, ear mucous membrane, genital mucous membrane, pharyngeal mucous membrane, respiratory tract mucous membrane, bronchial mucous membrane, pulmonary mucous membrane, gastric mucous membrane, enteric mucous membrane, or rectal mucous membrane, that is safe, useful as a prophylactic or therapeutic agent for infectious diseases or cancers, and capable of effectively inducing the systemic immune response and mucosal immune response. The present invention provides a mucosal vaccine composition to be administered to at least one mucous membrane selected from the group consisting of a human or animal intraoral mucous membrane, ocular mucous membrane, ear mucous membrane, genital mucous membrane, pharyngeal mucous membrane, respiratory tract mucous membrane, bronchial mucous membrane, pulmonary mucous membrane, gastric mucous membrane, enteric mucous membrane, and rectal mucous membrane, the mucosal vaccine composition containing: at least one antigen; and as an adjuvant, a lipopolysaccharide derived from at least one gram-negative bacterium selected from the group consisting of Serratia, Leclercia, Rahnella, Acidicaldus, Acidiphilium, Acidisphaera, Acidocella, Acidomonas, Asaia, Belnapia, Craurococcus, Gluconacetobacter, Gluconobacter, Kozakia, Leahibacter, Muricoccus, Neoasaia, Oleomonas, Paracraurococcus, Rhodopila, Roseococcus, Rubritepida, Saccharibacter, Stella, Swaminathania, Teichococcus, Zavarzinia, Pseudomonas, Achromobacter, Bacillus, Methanoculleus, Methanosarcina, Clostridium, Micrococcus, Flavobacterium, Pantoea, Acetobacter, Zymomonas, Xanthomonas, and Enterobacter, or a salt thereof, wherein a mass ratio between the adjuvant and the antigen (total mass of the adjuvant / total mass of the antigen) is 0.002 to 500.
Owner:NITTO DENKO CORP
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