Spleen-tonifying and qi-tonifying tea atomized liquid based on traditional Chinese medicine formula and preparation method of spleen-tonifying and qi-tonifying tea atomized liquid

Abstract

The invention discloses a spleen-tonifying and qi-tonifying tea atomized liquid based on a traditional Chinese medicine formula and a preparation method thereof. The atomized liquid consists of the following nine traditional Chinese medicinal materials: ginseng, astragalus membranaceus, black tea, liquorice, Chinese yam, pericarpium citri reticulatae, pinellia ternate, platycodon grandiflorum and poria cocos. Ginseng, astragalus membranaceus and black tea are combined as core components and cooperate with liquorice, Chinese yam and other adjuvants to form a compound system with remarkable spleen tonifying and qi tonifying effects. Ginseng and astragalus mongholicus have a synergistic effect to remarkably improve the qi tonifying effect, active ingredients contained in ginseng and astragalus mongholicus can enhance the immunity of the organism, improve the anti-fatigue ability, regulate blood glucose metabolism and improve exercise tolerance, and by adopting a modern atomization delivery technology, the active ingredients are rapidly absorbed through respiratory mucosa and directly enter human body circulation through lung circulation, so that the health care effect is achieved. According to the preparation method, the bioavailability is greatly improved, the defect that a traditional oral preparation possibly aggravates the metabolic burden of the liver is overcome, the atomization delivery mode avoids the first-pass effect, the spleen strengthening and qi tonifying effects can be achieved quickly, and a novel solution is provided for conditioning of the sub-health state.

Description

Technical Field

[0001] The present invention relates to the field of health-care beverages, and in particular to a spleen-strengthening and qi-invigorating tea atomized liquid based on a traditional Chinese medicine formula and a preparation method thereof. Background Art

[0002] Traditional Chinese Medicine (TCM) considers the spleen and stomach to be the foundation of our acquired constitution and the source of Qi and blood production. Healthy spleen and stomach function is directly related to the body's nutrient absorption and Qi and blood production. Therefore, Chinese herbs that invigorate the spleen and replenish Qi primarily aim to enhance spleen and stomach function, promote digestion and absorption, and help restore vitality. Common herbs for this purpose include Astragalus, Atractylodes macrocephala, Codonopsis pilosula, Ginseng, Licorice root, and Chinese Yam. According to TCM theory, the combination of these herbs can enhance the spleen and stomach's transport and transformation functions, improving symptoms such as indigestion and loss of appetite. For example, the combination of Astragalus and Atractylodes macrocephala can strengthen spleen and stomach function and promote digestion and absorption. Sijunzi Decoction, composed of Codonopsis pilosula, Atractylodes macrocephala, Poria cocos, and Licorice root, is a classic formula for invigorating the spleen and replenishing Qi, commonly used to treat various symptoms associated with spleen and stomach deficiency. Because most spleen-nourishing and Qi-tonifying herbs are warming in nature, excessive use can easily foster internal heat, deplete Yin essence, and trigger symptoms of Yin deficiency and hyperactivity of fire. It may cause symptoms such as hot flashes, night sweats, restlessness, dizziness and tinnitus. Some Qi-invigorating Chinese herbal medicines also have a promoting effect. Long-term use will cause hyperactivity of liver yang, and symptoms such as headaches, dizziness, blurred vision, tinnitus, insomnia, irritability, weakness in the waist and knees, heavy head and light feet, and unsteady walking will appear. Taking too much Chinese medicine will also increase the burden on the liver and even cause serious consequences such as liver failure. Summary of the Invention

[0003] The present invention provides a spleen-strengthening and qi-invigorating tea atomized liquid based on a traditional Chinese medicine formula and a preparation method thereof. The tea takes ginseng, astragalus, and black tea as core raw materials, and is combined with various spleen-strengthening and qi-invigorating Chinese medicinal materials. In order to avoid the burden on the liver caused by excessive oral administration of liquid Chinese medicine, modern atomization delivery technology is adopted to enable the effective ingredients to be rapidly absorbed through the respiratory mucosa and directly enter the human circulation through the pulmonary circulation, thereby greatly improving the bioavailability. The atomization delivery method not only avoids the first-pass effect, but also can achieve the rapid onset of spleen-strengthening and qi-invigorating effects, providing a new solution for the conditioning of sub-health conditions.

[0004] To achieve the above object, the present invention provides the following technical solutions:

[0005] On the one hand, the present invention provides a spleen-strengthening and qi-invigorating tea based on a traditional Chinese medicine formula, wherein the tea is composed of the following ingredients: ginseng, astragalus, black tea, licorice, yam, tangerine peel, pinellia, platycodon, and poria.

[0006] Preferably, the above tea contains the following weight ratios: 5g-8g ginseng, 5g-8g astragalus, 10g-20g black tea, 1g-3g licorice, 5g-10g yam, 3g-8g tangerine peel, 1g-5g pinellia, 5g-10g platycodon, and 6g-10g poria.

[0007] Preferably, the above tea contains the following weight ratios: 5g or 8g ginseng, 5g or 8g astragalus, 10g or 20g black tea, 1g or 3g licorice, 5g or 10g yam, 3g or 8g tangerine peel, 1g or 5g pinellia, 5g or 10g platycodon, and 6g or 10g poria.

[0008] Preferably, the tea beverage comprises the following proportions by weight: 7g ginseng, 7g astragalus, 15g black tea, 2g licorice, 12g yam, 5g tangerine peel, 3g pinellia, 8g platycodon, and 8g poria.

[0009] Preferably, the tea has the following pharmacological effects:

[0010] Ginseng: A qi-tonifying herb, considered the "king of herbs," its root contains various ginsenosides. It is warm in nature, with a sweet, slightly bitter, and slightly warm flavor. It enters the spleen and lung meridians. It has the effects of significantly replenishing vital energy, strengthening the pulse, strengthening the spleen and lungs, promoting fluid production and nourishing blood, and calming the mind and improving intelligence. Current pharmacological research suggests that ginseng also has multiple benefits, including regulating the central nervous system, fighting fatigue, protecting the myocardium, dilating blood vessels, resisting aging, regulating blood pressure, protecting and stimulating hematopoiesis, lowering blood lipids, combating atherosclerosis, preventing shock, protecting the liver, regulating the endocrine system, and regulating metabolism.

[0011] Astragalus: A Qi-tonifying herb with a sweet flavor and slightly warm nature; it enters the spleen and lung meridians. It replenishes Qi and raises Yang, strengthens the body's defense system, promotes diuresis and reduces swelling, and promotes the production of body fluids and nourishes the blood.

[0012] Black tea: a type of tea that is fully fermented (fermentation degree greater than 80%). The caffeine in black tea can stimulate the cerebral cortex to excite the nerve center, thereby refreshing the mind, making the thinking reaction more acute, and enhancing memory; the polyphenols, sugars, amino acids, pectin, etc. in black tea produce a chemical reaction with saliva, stimulating saliva secretion and moisturizing the mouth; at the same time, caffeine can regulate body temperature, maintain the body's physiological balance to achieve the effect of promoting salivation and clearing heat. At the same time, polyphenols can inhibit the activity of substances that destroy bone cells, playing a role in strengthening bones. Black tea also has the effects of nourishing the stomach, promoting digestion, resisting radiation, and delaying aging.

[0013] Licorice: A Qi-tonifying medicine that replenishes Qi and strengthens the middle, eliminates phlegm and relieves cough, detoxifies, relieves acute pain, and has multiple pharmacological effects such as anti-peptic ulcer, liver protection, antispasmodic, antiarrhythmic, antitussive and expectorant, detoxification, anti-inflammatory, antibacterial, antiviral, anti-allergic, adrenocortical hormone-like effects, as well as anti-tumor and anti-mutation.

[0014] Chinese Yam: A Qi-tonifying herb that replenishes Qi and nourishes Yin, tonifies the spleen, lungs, and kidneys, and astringes semen to stop leukorrhea. Chinese Yam polysaccharides can enhance nonspecific immunity, specific cellular immunity, and humoral immunity. Chinese Yam polysaccharides, total flavonoids, and Chinese Yam alcohol extracts have antioxidant and anti-aging effects.

[0015] Tangerine peel: a medicine for regulating qi, strengthening the spleen, drying dampness and resolving phlegm, with multiple pharmacological effects such as regulating gastrointestinal motility, promoting gastric juice secretion, anti-ulcer, liver protection, choleretic, anti-allergic, lipid-lowering, anti-platelet aggregation, antioxidant, expectorant, anti-asthmatic, antibacterial, and anti-tumor.

[0016] Pinellia: expectorant, antitussive and antiasthmatic drug. Pinellia has many pharmacological effects, including antitussive, expectorant, antiemetic, inhibiting gastric secretion, promoting bile secretion, anti-tumor, anti-arrhythmic, sedative and hypnotic, lowering blood lipids, antibacterial, anti-inflammatory, immune enhancement, and diuretic.

[0017] Platycodon grandiflorum: It has many pharmacological effects, such as expectorant, cough suppressant, antibacterial, anti-inflammatory, immune enhancement, inhibition of gastric juice secretion and anti-ulcer, lowering blood pressure and cholesterol, sedation, analgesia, antipyretic, anti-allergic, etc.

[0018] Poria: A diuretic and dampness-removing herb. It has multiple pharmacological effects, including diuresis, immune enhancement, gastrointestinal regulation, anti-tumor, liver protection, sedation, and antibacterial properties.

[0019] On the other hand, the present invention provides a spleen-strengthening and qi-invigorating tea atomized liquid based on a traditional Chinese medicine formula and a preparation method thereof, comprising the following steps:

[0020] S1 Weighing: Weigh the above-mentioned Chinese medicinal materials according to the weight ratio;

[0021] S2 Crushing: Pour the weighed Chinese medicine raw materials into the grinder and grind them into powder;

[0022] S3 sieving: the ground Chinese medicinal materials are passed through an 80-mesh sieve and subjected to boiling water reflux extraction for 1 hour;

[0023] S4 extraction: Filter the extract, add ethanol to the extract, and precipitate overnight to increase the ethanol concentration;

[0024] S5 concentration: the water-extracted alcohol precipitate is centrifuged to obtain a clear liquid, which is then vacuum concentrated to obtain an extract concentrate; S6 dissolution: the extract is dissolved in propylene glycol to obtain a propylene glycol solution;

[0025] S7 finished product: propylene glycol is added to the propylene glycol solution, with the propylene glycol accounting for 50%, and the remaining weight is supplemented with propylene glycol to prepare the atomized liquid.

[0026] Preferably, in step S4, ethanol is added twice, and the two alcohol precipitations are carried out overnight.

[0027] Preferably, in step S4, the ethanol concentration needs to be increased from 40% to 70%.

[0028] Preferably, glycerol is added in step S7, with the proportion of glycerol being 50%, and the remaining weight is supplemented by propylene glycol to prepare the atomized liquid.

[0029] Beneficial effects of the present invention

[0030] The present invention provides a spleen-strengthening and qi-invigorating tea atomization liquid based on a traditional Chinese medicine formula and a preparation method thereof. The core components are ginseng and astragalus combined with black tea, and auxiliary medicines such as licorice and yam are used to construct a compound system with significant spleen-strengthening and qi-invigorating effects. The synergistic effect of ginseng and astragalus significantly improves the qi-invigorating effect. The active ingredients contained in the two can not only enhance the body's immunity and improve anti-fatigue ability, but also regulate blood sugar metabolism, improve exercise endurance, and improve physical strength and energy. The caffeine in black tea can also regulate body temperature and maintain physiological balance in the body. Modern atomization delivery technology is used to enable the effective ingredients to be rapidly absorbed through the respiratory mucosa and directly enter the human circulation through the pulmonary circulation, greatly improving bioavailability, and solving the defect that traditional oral preparations may increase the metabolic burden of the liver. The atomization delivery method not only avoids the first-pass effect, but also can achieve rapid onset of spleen-strengthening and qi-invigorating effects, providing a new solution for regulating sub-health conditions. DETAILED DESCRIPTION

[0031] To make the objectives, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below with reference to the embodiments. The embodiments of the present invention are only used to explain the present invention and are not intended to limit the present invention.

[0032] Example 1

[0033] A spleen-strengthening and qi-tonifying tea nebulizer based on a traditional Chinese medicine formula comprises the following raw materials in parts by weight: 5g ginseng, 5g astragalus, 10g black tea, 1g licorice, 5g yam, 3g tangerine peel, 1g pinellia, 5g platycodon, and 6g poria.

[0034] A spleen-strengthening and qi-invigorating tea nebulizer liquid based on a traditional Chinese medicine formula comprises the following steps: weighing each Chinese medicinal raw material according to a weight ratio, pouring the weighed Chinese medicinal raw materials into a grinder and grinding them into powder, passing the ground Chinese medicinal materials through an 80-mesh sieve, extracting them under boiling water reflux for 1 hour, filtering the extract, adding ethanol to the extract twice, precipitating them with alcohol twice overnight to increase the ethanol concentration to 70%, centrifuging the water-extracted and alcohol-precipitated liquid to obtain a clear liquid, vacuum concentrating the extract to obtain an extract extract, dissolving the extract with propylene glycol to obtain a propylene glycol solution, adding glycerol to the propylene glycol solution to obtain 50% glycerol, and supplementing the remaining weight with propylene glycol to obtain the nebulizer liquid.

[0035] Example 2

[0036] A spleen-strengthening and qi-tonifying tea nebulizer based on a traditional Chinese medicine formula comprises the following raw materials in parts by weight: 7g ginseng, 7g astragalus, 15g black tea, 2g licorice, 12g yam, 5g tangerine peel, 3g pinellia, 8g platycodon, and 8g poria.

[0037] The preparation method is the same as that of Example 1.

[0038] Example 3

[0039] A spleen-strengthening and qi-invigorating tea nebulizer based on a traditional Chinese medicine formula comprises the following raw materials in parts by weight: 8g ginseng, 8g astragalus, 20g black tea, 3g licorice, 10g yam, 8g tangerine peel, 5g pinellia, 10g platycodon, and 10g poria.

[0040] The preparation method is the same as that of Example 1.

[0041] Comparative Example 1 (without adding raw materials ginseng and astragalus)

[0042] A spleen-strengthening and qi-invigorating tea nebulizer based on a traditional Chinese medicine formula comprises the following raw materials in parts by weight: 10g black tea, 1g licorice, 5g yam, 3g tangerine peel, 1g pinellia, 5g platycodon, and 6g poria.

[0043] The preparation method is the same as that of Example 1.

[0044] Comparative Example 2 (both ginseng and astragalus were reduced to 2g)

[0045] A tea nebulizer for invigorating the spleen and replenishing qi based on a traditional Chinese medicine formula, comprising the following ingredients in parts by weight: 2g ginseng, 2g astragalus, 15g black tea, 2g licorice, 12g yam, 5g tangerine peel, 3g pinellia, 8g platycodon, and 8g poria.

[0046] The preparation method is the same as that of Example 1.

[0047] Comparative Example 3 (without adding raw materials yam, tangerine peel, and platycodon)

[0048] A spleen-strengthening and qi-invigorating tea nebulizer based on a traditional Chinese medicine formula comprises the following raw materials in parts by weight: 8g ginseng, 8g astragalus, 20g black tea, 3g licorice, 5g pinellia, and 10g poria.

[0049] The preparation method is the same as that of Example 1.

[0050] Experimental testing

[0051] 60 people, regardless of gender or age, were randomly selected and divided into 6 groups, with 10 people in each group. The first group inhaled the atomized liquid prepared in Example 1, the second group inhaled the atomized liquid prepared in Example 2, the third group inhaled the atomized liquid prepared in Example 3, the fourth group inhaled the atomized liquid prepared in Comparative Example 1, the fifth group inhaled the atomized liquid prepared in Comparative Example 2, and the sixth group inhaled the atomized liquid prepared in Comparative Example 3.

[0052] Atomization method: unlimited atomization, twice a day, 20 minutes each time.

[0053] After inhalation of the nebulized solution, the subjects were followed up for 3 months and the number of people with and without the effect was counted.

[0054] Effective standards: increased appetite, improved physical strength (reduced fatigue), rosy complexion, improved complexion, and enhanced resistance (reduced colds).

[0055] Table 1 Experimental effects of Examples 1-3 and Comparative Examples 1-3 on the test population

[0056]

[0057] It can be seen from the above experimental tests and Table 1 that most of the people who inhaled the atomized tea liquid of Examples 1, 2 and 3 showed obvious improvement, especially among the 10 people who inhaled the tea atomized liquid of Example 3, all of them had obvious changes, increased appetite, improved physical strength, enhanced resistance, and reduced the frequency of colds. Among the 10 people in the comparison example 1 that inhaled the atomized tea liquid without ginseng and astragalus, no one felt that their resistance was enhanced, while the medicinal materials ginseng and astragalus in the comparison example 2 were only reduced in amount, and only a few people felt that their resistance was enhanced. Among the 10 people in the comparison example 3 that inhaled the atomized tea liquid without yam, tangerine peel and platycodon, basically no one felt that their appetite was opened and their appetite was enhanced.

[0058] In summary, the present invention provides a spleen-strengthening and qi-tonifying tea nebulized liquid based on a traditional Chinese medicine formula. The medicinal ingredients are scientifically proportioned and complement each other. With the help of modern atomization technology, the nebulized liquid is made and rapidly absorbed by the respiratory tract and lungs through atomization inhalation. It not only effectively strengthens the spleen and replenishes qi, but also avoids the process of oral Chinese medicine that requires absorption and metabolism by the digestive system.

[0059] The embodiments of the present invention are only specific descriptions of the technical solutions, not limitations of the technical solutions. Any substitutions or modifications made by those skilled in the art without changing the essential contents of the present invention shall fall within the protection scope of the present invention.

Claims

1. A tea drink for strengthening the spleen and replenishing qi based on a traditional Chinese medicine formula, characterized in that: It at least contains the following raw materials: ginseng, astragalus, and black tea.

2. The tea drink according to claim 1, characterized in that The raw material components also include: liquorice, yam, tangerine peel, pinellia, platycodon, and poria.

3. The tea drink according to claim 2, characterized in that It is prepared according to the following weight ratio: 5g-8g ginseng, 5g-8g astragalus, 10g-20g black tea, 1g-3g licorice, 5g-10g yam, 3g-8g tangerine peel, 1g-5g pinellia, 5g-10g platycodon, and 6g-10g poria.

4. The tea drink according to claim 3, characterized in that It is prepared according to the following weight ratio: 5g or 8g of ginseng, 5g or 8g of astragalus, 10g or 20g of black tea, 1g or 3g of licorice, 5g or 10g of yam, 3g or 8g of tangerine peel, 1g or 5g of pinellia, 5g or 10g of platycodon, and 6g or 10g of poria.

5. The tea drink according to claim 3, characterized in that It is prepared according to the following weight ratio: 7g ginseng, 7g astragalus, 15g black tea, 2g licorice, 12g yam, 5g tangerine peel, 3g pinellia, 8g platycodon, and 8g poria.

6. The method for preparing the tea atomized liquid according to claim 2, wherein: The method comprises the following steps: S1 weighing: weighing the above-mentioned Chinese medicinal materials according to the weight ratio; S2 Crushing: Pour the weighed Chinese medicine raw materials into the grinder and grind them into powder; S3 sieving: the ground Chinese medicinal materials are passed through an 80-mesh sieve and subjected to boiling water reflux extraction for 1 hour; S4 extraction: Filter the extract, add ethanol to the extract, and precipitate overnight to increase the ethanol concentration; S5 concentration: The water-extracted alcohol precipitate is centrifuged to obtain a clear liquid, which is then vacuum concentrated to obtain an extract concentrate; S6 dissolution: dissolving the extract with propylene glycol to prepare a propylene glycol solution; S7 finished product: propylene glycol is added to the propylene glycol solution, with the propylene glycol accounting for 50%, and the remaining weight is supplemented with propylene glycol to prepare the atomized liquid.

7. The method for preparing the tea atomized liquid according to claim 6, characterized in that: In step S4, ethanol needs to be added twice, and the two alcohol precipitations are carried out overnight.

8. The method for preparing the tea atomized liquid according to claim 6, wherein: In step S4, the ethanol concentration needs to be increased from 40% to 70%.

9. The method for preparing the tea atomized liquid according to claim 6, wherein: In step S7, glycerol is added, the glycerol accounts for 50%, and the remaining weight is supplemented by propylene glycol to prepare an atomized liquid.

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