10 results about "Hematinic" patented technology

The application relates to the technical field of meat processing, in particular to a vacuum circulation pickling method for meat. The method comprises the following steps: submerging meat pieces to be pickled in pickling liquid added with 0.1% hematin iron; first, applying a transient high-voltage electromagnetic pulse to precisely perforate the cell membrane of the meat; then, applying an alternating vortex magnetic field with a specific frequency; utilizing the high-frequency micro-vibration of the hematin iron in the magnetic field to generate a magnetohydrodynamic effect, expand the micro-pore channel and pump the pickling material molecules into the cell interior; finally, combining vacuum circulation alternating treatment to further press the pickling material into the tissue gap. The added hematin iron significantly enhances the promotion effect of the magnetic field on the pickling material delivery, and the pickling time is shortened to 30 minutes or less. It is proved through measurement that the pickling liquid absorption rate of the process is high, the penetration reaches the geometric center of the meat pieces, and the integrity and water holding capacity of the meat structure are perfectly preserved.

The application provides a low-temperature vacuum-multicavity evaporation linkage heme iron preparation method and device, relates to the technical field of biological medicine and functional food deep processing, and solves the problems of local overheating and fouling caused by traditional wall heat transfer.

This invention relates to the technical field of pet food, and more particularly to a functional pet nutritional supplement and pet nutritional food and its preparation method, comprising 10%–15% beef liver chunks, 20%–30% chicken breast strips, 35%–45% a mixture of cooked rice flour / corn / rice, 0.3%–1.0% chicken oil, 0.3%–1.0% fish oil, 2%–5% pumpkin puree, 1%–3% chopped carrots, 3%–7% egg yolk powder, 3%–7% a mixture of traditional Chinese medicine extracts, 0.5%–1.5% amino acid and mineral premix, 0.5%–1.5% vitamin and antioxidant premix, 0.0001%–0.001% probiotic mixture, 0.05%–0.3% potassium sorbate, 0.05%–0.3% sodium benzoate, 0.05%–0.2% citric acid, and BHA / BHT. 0.05%–0.2%, with the remainder being chicken broth. Beef liver is rich in heme iron, which, combined with lecithin in egg yolk powder, promotes iron absorption. Traditional Chinese medicine extracts significantly reduce IL-6, IgG, and IgM levels, regulating hyperimmune states. Meanwhile, ingredients such as astragalus enhance normal immunity, achieving a balance of "strengthening the body's resistance and eliminating pathogens."

The present invention discloses a heme iron – glycine chelated iron supplement preparation, belonging to the technical field of nutritional and pharmaceutical preparations. The preparation employs a four-source composite of heme iron, glycine chelated iron, ferrous gluconate, and ferrous lactate, enabling iron supplementation via heme receptor absorption, amino acid chelation pathways, and ionic diffusion. This design overcomes the limitations of single iron sources, including gastrointestinal irritation and low absorption of inorganic iron, dietary inhibition of conventional organic iron, and the high cost or slow onset of novel iron sources. The four iron sources act synergistically to reduce free iron ions and integrate multiple absorption pathways. As a result, gastrointestinal irritation is minimized, and the inhibitory effects of phytic acid, oxalic acid, and tannins are reduced, enabling stable and efficient intestinal absorption. The preparation achieves non-irritating, highly bioavailable, and sustained iron supplementation.

The application belongs to the technical field of hematin quantitative detection, and specifically discloses application of methylene blue cyclopropyl formylated derivative as a chromogenic substrate for detecting hematin, and uses methylene blue cyclopropyl formylated derivative AMB as a chromogenic substrate for detecting hematin Hemin; compared with a classical substrate TMB, the methylene blue cyclopropyl formylated derivative AMB of the application has higher sensitivity in the detection of hematin Hemin; in addition, the amino protons of the methylene blue cyclopropyl formylated derivative AMB of the application are fully substituted by methyl, which inhibits the participation of active oxygen free radicals in oxidation, but is still sensitive to the oxidation pathway of ferric free radicals, has better selectivity compared with TMB, and the AMB system can effectively detect hematin Hemin in a serum sample. Therefore, it can be said that for the detection of hematin Hemin, AMB is a more excellent colorimetric substrate than TMB.

This invention provides a method and apparatus for extracting heme iron based on a dual-membrane cascade and oxygen isolation protection, belonging to the field of biochemical separation and purification technology. The method first constructs a pneumatically suspended hemolytic environment, utilizing a metal sintered microporous distributor to generate a micron-sized inert bubble fluidized bed, achieving red blood cell disruption and deep deoxygenation under zero mechanical shear conditions, solving the molecular damage and oxidation problems caused by traditional processes. Then, a gas-liquid co-flow ultrafiltration mechanism is employed, introducing pulsed plug flow drive to physically peel off the protein gel layer on the membrane surface online, achieving dynamic anti-clogging and long-term stability in the macromolecular separation process. Finally, transmembrane partial pressure extraction is performed based on a reverse gas-scan nanofiltration model, distinguishing the migration paths of water molecules and dissolved oxygen, outputting a highly active concentrate and a closed-loop circulating gas flow. This invention effectively improves the extraction efficiency of the product Fe. 2+ Retention rate, purity, and continuity of industrial production.

This invention relates to the field of heme purification technology, and more particularly to a method for extracting and purifying heme chloride. The method includes: taking fresh animal blood, centrifuging to collect the lower red blood cell precipitate, adding physiological saline, mixing, and washing; adding a 1-10% ethanol solution, mixing, and ultrasonically disrupting at 300-800W for 15-60 seconds to obtain a red blood cell lysate; adding an acidic acetone solution to the red blood cell lysate, mixing, and extracting at room temperature, centrifuging to collect the supernatant to obtain an acidic acetone extract; slowly adding NaOH solution to adjust the pH; adding sodium acetate, stirring, allowing to stand, collecting the precipitate, washing, and drying to obtain a crude product; packing a silica gel column; loading the crude product onto an eluent, eluting with an eluent and collecting the eluent fraction containing the target product; the eluent includes dichloromethane, methanol, and formic acid; and removing the mobile phase from the eluent fraction. The advantages are: simple process, low cost, environmentally friendly, and the ability to obtain a high-purity product.

The application discloses a self-derived protein anticoagulant coating and a preparation method and application thereof. The coating utilizes the oxidation of hydrogen peroxide generated by the reaction of an oxidizing agent or a reducing agent with oxygen in the air, is based on the endogenous active center (such as hematin) removal mechanism of self-extracted proteins (such as hemoglobin), induces the oxidative self-assembly of the proteins, and loads an anticoagulant in the assembly process to form a protein-anticoagulant composite nanofilm. The application utilizes the self-proteins to avoid the transmission risk of pathogens such as HIV, PERVs and prions from the source; the preparation method is simple and rapid, and the obtained coating has excellent adhesion stability, good biocompatibility and anti-biofouling capacity on the surface of various substrates. In-vitro and in-vivo experiments prove that the coating has superior anticoagulant performance, reduces the risk of bleeding and liver and kidney toxicity, and can be used for the surface modification of blood-contacting medical devices such as a heart stent, an artificial blood vessel, a central venous catheter and an extracorporeal oxygenator.

The application discloses a preparation method and application of hematin. The hematin is prepared from a fermentation culture of propionic acid bacteria (Corallicola sp.) SCSIO 13291 CGMCC No. 14538. The hematin is prepared from the propionic acid bacteria (Corallicola sp.) SCSIO 13291, and therefore can be applied to hematin-related drugs and food.

The present application relates to a kind of ice feeling comfrey soothing cream and its preparation method and application, the ice feeling comfrey soothing cream includes comfrey extract, anti-allergic component, soothing component, cool component, moisturizing component and auxiliary agent;The anti-allergic component includes ikdoine, sanqi root extract, white and root extract, three leaf burweed root extract, hawthorn fruit extract and ginseng root extract.In the present application, comfrey extract is creatively added in soothing cream, which can significantly reduce the skin hemoglobin EI value and reduce skin temperature.Add anti-allergic component, cool component, soothing component and moisturizing component, by inhibiting inflammatory factors, reducing temperature, relieving skin discomfort and increasing the moisture level of skin, soothing effect is realized from four aspects.