The invention relates to a high-purity ginkgolide and its composition. It is a white powder with slightly bitter taste. The content of ginkgolide A is 10-20%, the content of ginkgolide B is 10-20%, and the content of ginkgolide C is 10-20%. 5-15%, the bilobalide content is 30-50%, and the total lactone content is 80-95%. Ginkgo biloba is used as raw material, heated and refluxed with ethanol solution with a mass fraction of 20-80% to extract, the extract is concentrated to recover ethanol, separated by a macroporous resin column, desorbed by ethanol, diluted with water, and then passed through a gel-type hydrogen bond Adsorption and desorption of the adsorption resin, collection of effluent and desorption liquid, concentration, drying, ethanol dissolution, activated carbon decolorization, concentration and drying. The preparation process is simple, reliable, low in cost and high in yield, and no toxic organic solvent is used in the process, which is an environment-friendly process. The high-purity ginkgolide is used as an active ingredient to prepare a composition that can be used as various preparations (capsules, tablets, oral liquids, granules, powders, injections, etc.) of ginkgolide medicines or health care products.