The invention relates to a water-soluble
ginkgo leaf extract and its preparation technology, The method of the invention comprises: taking common
ginkgo biloba as a
raw material, mixing with
acetone and extracting, concentrating, diluting by adding water, cryoprecipitating, filtering, performing a
gradient elution to a filtrate through macroporous adsorption resin, carrying out an
alcohol precipitation by
ethanol with high purity,
water extraction and cryoprecipitating, concentrating,
drying to obtain the water-soluble
ginkgo leaf extract, wherein the content of total flavonol
glycoside is greater than or equal to 27%; the content of
lactone content is 9%-12%, wherein the content of
Terpene Lactones A is greater than or equal to 2.1%, the content of
Terpene Lactones B is greater than or equal to 0.9%, the content of
Terpene Lactones C is greater than or equal to 1.2%, and the
lactone ratio of GA:GB:GC is close to 7:3:4; the water-
solubility is greater than and equal to 10%; the
ginkgolic acid is less than and equal to 1ppm, which can be taken as a
raw material used for injection. The invention has the advantages of simple production technology, high and stable product quality, high finished product yield, low cost and good economic benefit.