The invention relates to a water-soluble 
ginkgo leaf extract and its preparation technology, The method of the invention comprises: taking common 
ginkgo biloba as a 
raw material, mixing with 
acetone and extracting, concentrating, diluting by adding water, cryoprecipitating, filtering, performing a 
gradient elution to a filtrate through macroporous adsorption resin, carrying out an 
alcohol precipitation by 
ethanol with high purity, 
water extraction and cryoprecipitating, concentrating, 
drying to obtain the water-soluble 
ginkgo leaf extract, wherein the content of total flavonol 
glycoside is greater than or equal to 27%; the content of 
lactone content is 9%-12%, wherein the content of 
Terpene Lactones A is greater than or equal to 2.1%, the content of 
Terpene Lactones B is greater than or equal to 0.9%, the content of 
Terpene Lactones C is greater than or equal to 1.2%, and the 
lactone ratio of GA:GB:GC is close to 7:3:4; the water-
solubility is greater than and equal to 10%; the 
ginkgolic acid is less than and equal to 1ppm, which can be taken as a 
raw material used for injection. The invention has the advantages of simple production technology, high and stable product quality, high finished product yield, low cost and good economic benefit.