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45 results about "Ginkgo nut" patented technology

Medicinal and edible traditional Chinese medicine composition as well as preparation method, traditional Chinese medicine preparation and application thereof

The invention belongs to the field of traditional Chinese medicine biological medicine, and particularly relates to a medicinal and edible traditional Chinese medicine composition and a preparation method, a traditional Chinese medicine preparation and application thereof. The invention provides a medicinal and edible traditional Chinese medicine composition which comprises the following components in parts by weight: ginseng, lily, Chinese yam, angelica sinensis, poria cocos, pericarpium citri reticulatae, ginkgo, radix polygonati officinalis, rhizoma zingiberis and honey-fried licorice root. The preparation method comprises the following steps: mixing the raw materials, adding water for soaking, extracting with water, filtering an extracting solution, concentrating filtrate, and collecting paste to obtain a semi-solid extract or a liquid extract; and further drying the obtained semi-solid extract or liquid extract to obtain the solid extract of the traditional Chinese medicine composition. The traditional Chinese medicine composition provided by the invention adopts an all-medicine-food homologous formula, has no toxic or side effect, is suitable for being taken by various people for a long time, has definite functionality, and is creatively compatible aiming at chronic respiratory system diseases, especially chronic obstructive pulmonary disease in a stable phase complex pathogenesis; the traditional Chinese medicine composition can be applied to health-care products for adjuvant therapy of chronic obstructive pulmonary disease or drugs for treatment of chronic obstructive pulmonary disease.
Owner:ANHUI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE

A traditional chinese medicine composition for pancreatic cancer

The application discloses a traditional Chinese medicine composition for treating pancreatic cancer, which comprises the following medicinal materials in parts by weight: 1-20 parts of Chinese cork tree, 1-15 parts of ginkgo, 1-10 parts of evodia, 1-10 parts of tripterygium, 1-15 parts of two-edged needle, 1-15 parts of radix astragali, and 1-10 parts of jujube. The application further discloses a medicine taking the traditional Chinese medicine composition as raw materials and a preparation method of the medicine. In addition, the application further discloses application of the traditional Chinese medicine composition or the medicine in preparation of a medicine for treating pancreatic cancer.
Owner:INST OF BASIC RES & CLINICAL MEDICINE CHINA ACAD OF CHINESE MEDICAL SCI

Beverage with effect of enhancing immunity and preparation method thereof

PendingCN121817304ACoffee extractionBiotechnologyCichorium
The invention discloses a beverage with an immunity enhancing effect and a preparation method thereof. The beverage with the immunity enhancing effect is prepared from the following raw materials in parts by weight: 5-10 parts of liquorice, 5-10 parts of schizophyllumcommuneh, 5-10 parts of endive, 5-10 parts of semen torreya, 3-5 parts of astragalus membranaceus, 5-8 parts of scutellaria baicalensis leaves, 2-3 parts of L-cysteine, 5-8 parts of coffee, 2-3 parts of lemon and 1-3 parts of wild bolete. According to the drink with the immunity enhancing effect, the drink has the effects of tonifying spleen and replenishing qi, nourishing the body, tonifying qi and lifting yang, enhancing the immunity, promoting salivation and soothing the nerves, enhancing the physique, relieving fatigue and the like by limiting all the raw materials and the dosage, and under the combined action of all the raw materials, the symptoms of easy tiredness, fatigue and easy cold caused by low immunity can be relieved; therefore, the beverage with the effect of enhancing the immunity can improve the physique of the human body and enhance the immunity, and the effect is remarkable.
Owner:赵为兴

Gene GbCYP701A6 for promoting synthesis of ginkgo terpene lactones and application of gene GbCYP701A6

PendingCN122012537AOxidoreductasesFermentationBilobalidesGinkgo nut
The invention discloses a gene GbCYP701A6 for promoting synthesis of ginkgo terpene lactones and application of the gene GbCYP701A6. The nucleotide sequence of the gene GbCYP701A6 is shown as SEQ ID NO.1, and the amino acid sequence of protein expressed by the gene GbCYP701A6 is shown as SEQ ID NO.2. The invention further discloses a preparation method of the gene GbCYP701A6. According to the invention, a brand new gene GbCYP701A6 is cloned from gingko for the first time. The GbCYP701A6 gene is transferred into a ginkgo biloba body, the GbCYP701A6 gene is over-expressed, the contents of terpene lactones including ginkgolide A, ginkgolide B, ginkgolide C and bilobalide in ginkgo biloba are remarkably increased, and the contents of the ginkgolide A, ginkgolide B, ginkgolide C and bilobalide are remarkably reduced when the gene is silently expressed, so that the gene is a key gene for promoting synthesis of the ginkgo terpene lactones, and the GbCYP701A6 gene can be used for preparing the ginkgo biloba terpene lactones. Therefore, the regulation and control of the expression of the GbCYP701A6 has important application value in the aspects of improving the medicinal quality of the ginkgo leaves and the like.
Owner:YANGZHOU UNIV

Whitening and spot-fading composition and application thereof

PendingCN121465940ACosmetic preparationsToilet preparationsBiotechnologyViscum album leaf extract
The invention discloses a whitening and spot-fading composition and application thereof, and belongs to the field of cosmetics. The composition comprises the following raw materials: a cynanchum atratum extract, a morinda citrifolia extract, a fucus extract, a trifolium pretense extract and a mistletoe leaf extract, and the raw materials are synergistically compounded, so that the composition provided by the invention has remarkable whitening and spot-fading effects.
Owner:GUANGDONG FADI COSMETICS TECH CO LTD +1

A traditional Chinese medicine composition for clearing lung and relieving asthma, granular medicine and application thereof

ActiveCN118320037BSignificant clinical effectHigh clinical controlGranular deliveryRespiratory disorderDiseaseFormulary
This invention provides a traditional Chinese medicine composition for clearing the lungs and relieving asthma, its granules, and their applications, relating to the field of traditional Chinese medicine technology. The traditional Chinese medicine composition for clearing the lungs and relieving asthma of this invention is prepared from the following raw materials in the indicated weight proportions: Ephedra 8-12g, Earthworm 8-12g, Bitter Apricot Kernel 8-12g, Mulberry Bark 8-12g, Coltsfoot Flower 13-18g, Stemona 13-18g, Platycodon Root 8-12g, Prepared Pinellia Rhizome 8-12g, Tangerine Peel 8-12g, Ginkgo Root 8-12g, Scutellaria Root 13-18g, Perilla Seed 13-18g, Trichosanthes Peel 25-35g, Peucedanum Root 8-12g, and Belamcanda Rhizome 8-12g. The traditional Chinese medicine formula provided by this invention has good clinical efficacy in treating chronic obstructive pulmonary disease, with high clinical control and efficacy rates, and a high overall effective rate.
Owner:HAINAN PROVINCIAL HOSPITAL OF TRADITIONAL CHINESE MEDICINE

A composition of ginkgo biloba leaf extract and a method for preparing the same

PendingCN122297541ABiotechnologyGinkgo Biloba Leaf Extract
This invention provides a composition of Ginkgo biloba extract and its preparation method. The composition consists of Ginkgo biloba extract (calculated as total flavonol glycosides) and dipyridamole in a dosage ratio of 10:4. The preparation method can significantly improve product yield, reduce production costs, and significantly increase the content of the main components of the produced Ginkgo biloba extract, namely total flavonol glycosides and terpene lactones. It can also reduce the content of poorly water-soluble ginkgolides and harmful impurities such as ginkgolic acid, control its microbial level, and improve the stability and safety of the Ginkgo biloba extract preparation product of this invention.
Owner:TONGHUA GUHONG PHARM CO LTD

Ginkgo functional edible gel product for relieving airway inflammation and preparation method thereof

The invention discloses a ginkgo functional edible gel product for relieving airway inflammation and a preparation method of the ginkgo functional edible gel product. The ginkgo functional edible gel product is prepared from the following components in percentage by mass: 5.15% of ginkgo ethyl acetate extract, 8% of ginkgo RS3 type resistant starch, 2% of ginkgo polypeptide, 10% of gelatin, 15% of malt syrup, 0.19% of acidity adjusting solution and 0.3% of momordica grosvenori glucoside. According to the invention, an edible gel product is used as a carrier, and ginkgo seed ethyl acetate extract and ginkgo seed RS3 type resistant starch with functional activity of relieving airway inflammation, ginkgo seed polypeptide, low-calorie and decayed tooth-resistant momordica grosvenori glucoside and malt syrup are added as sweetening agents; according to the invention, gingko is used as a raw material to prepare an edible gel product containing gingko micromolecular active substances, resistant starch and other multi-component functional components, so that the application range of gingko resources is expanded, the utilization rate of each component of gingko is improved, and the variety of functional leisure food is enriched at the same time.
Owner:NANJING FORESTRY UNIV

Ginkgo biloba extract composition and preparation method thereof

PendingCN121221661AGinkgophyta medical ingredientsBlood disorderBiotechnologyGinkgo Biloba Leaf Extract
The invention provides a composition of ginkgo biloba extract and a preparation method thereof, the composition is composed of ginkgo biloba extract (based on total flavonol glycosides) and dipyridamole according to a dosage ratio of 10: 4, and the preparation method can significantly improve the product yield, reduce the production cost and improve the product quality. The ginkgo biloba extract prepared by the method has the advantages that the content of main components, namely total flavonol glycosides and terpene lactones, of the ginkgo biloba extract is obviously increased, the content of bilobalide with poor water solubility and the content of a harmful impurity, namely ginkgolic acid can be reduced, the microbial level of the ginkgo biloba extract is controlled, and the stability and safety of the ginkgo biloba extract preparation product are improved.
Owner:TONGHUA GUHONG PHARM CO LTD

Ginkgo seed peptide with anti-inflammatory and anti-oxidation effects and preparation method thereof

The invention belongs to the technical field of preparation of protein peptides, and particularly relates to a ginkgo peptide with anti-inflammatory and anti-oxidation effects and a preparation method of the ginkgo peptide. According to the present invention, with the process of sodium carbonate-citric acid-hot water three-stage pretreatment, composite fermentation and double enzymolysis, the toxic components in the ginkgo can be efficiently removed, the complex structure of the ginkgo can be disintegrated, the macromolecular protein can be efficiently converted into the small molecule peptide, and the rich specific active components of the ginkgo can be retained; therefore, in the ginkgo peptide provided by the invention, the residual amount of ginkgolic acid is less than or equal to 10mg / kg, the residual amount of cyanide is less than or equal to 0.5 mg / kg, and the ginkgo peptide meets the food safety standard; meanwhile, the protein content in the ginkgo peptide is larger than or equal to 70%, the average molecular weight is smaller than or equal to 1000 Da, the scavenging rate of the ginkgo peptide to DPPH free radicals is larger than or equal to 85%, and the inhibition rates of the ginkgo peptide to inflammatory factors TNF-alpha and IL-6 are larger than or equal to 30%, that is, the ginkgo peptide has the advantages of being high in toxic component residue removal rate, high in protein content, reasonable in molecular weight distribution, sufficient in anti-inflammatory and anti-oxidation biological activity and the like; and a brand-new and efficient way is provided for high-value utilization of ginkgo resources.
Owner:HUBEI RUIBANG BIOTECHNOLOGY CO LTD

Semen euryales shell opening knife and working method thereof

The invention discloses a gordon euryale seed shell opening cutter and a working method thereof, and belongs to the field of agricultural product processing equipment. The gordon euryale seed shell opening cutter comprises a fixing frame, a plurality of blades, a driving part and a supporting part, the fixing frame is provided with a machining cavity, the driving part is installed on the fixing frame, the blades are installed on the driving part, the blades are arranged in the machining cavity, the supporting part is located below the blades, the blades are distributed in the circumferential direction of the supporting part, and the driving part is used for making the blades move in the radial direction of the machining cavity. The gordon euryale seed shells are cut through the blades which do radial reciprocating motion, and the probability that part of gordon euryale seed shells are clamped between the blades to affect next gordon euryale seed processing is reduced.
Owner:沈建林

Use of a traditional Chinese medicine composition in the preparation of a medicine for viral pneumonia

ActiveCN118384213BReduce lung index in mixed-infected miceIncreased lung index in infected miceAntibacterial agentsAntiviralsPharmaceutical drugSaposhnikovia
The application relates to an application of a traditional Chinese medicine composition in a drug for viral pneumonia, which comprises 10-15 parts of wind-preventing, 10-15 parts of perilla leaf, 2-6 parts of Ephedra, 7-9 parts of Schisandra chinensis, 7-9 parts of white ginkgo, 7-9 parts of bitter almond, 7-9 parts of purple aster, 7-9 parts of dogwood fruit and 7-9 parts of lily of the valley. The traditional Chinese medicine composition can obviously inhibit the increase of the lung index of respiratory syncytial virus (RSV) infected mice and has a better treatment effect on viral pneumonia.
Owner:JIANGSU KANION PHARMA CO LTD

Ornament (Ginkgo Nut)

ActiveCN310061050SBiotechnologyGinkgo nut
Owner:山东医学高等专科学校

Preparation method for improving solubility of ginkgo nut kernel formula granules

PendingCN122624403ABiotechnologyCellulose
This invention discloses a method for preparing ginkgo seed formula granules with improved solubility, belonging to the technical field of traditional Chinese medicine formula granule preparation. The method includes: adding water to ginkgo seed slices, performing a warm extraction at 55-65°C, filtering and concentrating to obtain a ginkgo seed concentrate; adding 6%-10% (by weight of the ginkgo seed slices) of hydroxypropyl-β-cyclodextrin and 0.3%-1.0% of sodium carboxymethyl cellulose to the ginkgo seed concentrate, and stirring to mix; vacuum drying the resulting material at 40-50°C, followed by pulverization and granulation to obtain ginkgo seed formula granules. This invention improves the dispersion and static stability of ginkgo seed formula granules during reconstitution by coordinating extraction conditions, excipient composition and addition stages, and the low-temperature drying process.
Owner:JING BRAND +1

A fermented traditional Chinese medicine product and a preparation method and application thereof

PendingCN122097535AHigh dissolution rateImprove bioavailabilityRespiratory disorderPlant ingredientsBiotechnologyEleutherococcus senticosus
This invention discloses a fermented traditional Chinese medicine product, its preparation method, and its application, belonging to the field of traditional Chinese medicine fermentation technology. The product uses peppermint, astragalus, wolfberry, mulberry bark, anemarrhena, arborvitae leaf, scrophularia, cimicifuga, elsholtzia, angelica, lily, ginkgo, licorice, schisandra, eleutherococcus senticosus, ophiopogon japonicus, and dried ginger as raw materials, sorghum as a co-fermentation raw material, and brewing liquid as a fermentation enhancer. The process involves pretreatment of the traditional Chinese medicine, co-cooking with sorghum, saccharification with small-grain starter, segmented fermentation, extraction and purification, and post-treatment. This invention utilizes a "compound traditional Chinese medicine ~ sorghum" co-fermentation system, combined with the microbial community and active substances rich in brewing liquid, to increase the dissolution rate of active ingredients such as astragaloside A, lily polysaccharide, and wolfberry polysaccharide in the traditional Chinese medicine by more than 50%, while simultaneously converting them into easily absorbed small molecule derivatives. The finished product has an alcohol content controlled at 6-8 degrees, which not only promotes the absorption of active ingredients but also possesses synergistic effects of clearing the lungs and regulating qi, tonifying qi and benefiting the lungs, moistening the lungs and relieving cough, and clearing heat and resolving phlegm. The process enables the resource utilization of yellow water from brewing, reducing costs by 35%, and the product exhibits excellent stability, making it suitable for industrial production. It also has significant value in the field of lung function regulation and health care.
Owner:YUNNAN MINGQU BIOTECHNOLOGY DEVELOPMENT CO LTD +1

A composition for treating athlete's foot

PendingCN122424230AAntifungalGinkgo nut
The present application relates to a long-acting antibacterial material with antifungal and wound healing promoting effects, in particular to an antifungal composition for treating tinea and a preparation method thereof. The antifungal composition for treating tinea disclosed by the present application takes ginkgo extract and walnut peel as main antifungal and wound healing promoting components. Test proves that the long-acting antibacterial material has the characteristics of wide antibacterial spectrum, rapid bacteriostasis and skin affinity, has obvious inhibitory effect on Candida albicans, Epidermophyton floccosum, Trichophyton rubrum and Trichophyton gypseum, can promote wound healing, can be stored for a long time, has low production cost, high safety, and has good application prospect and market potential.
Owner:ZHEJIANG UNIV OF TECH

Fermented composition for improving lung ventilation function and method of preparation

The application provides a fermented composition for moistening and nourishing the lung and a preparation method. The fermented composition comprises the following components in parts by mass: 20-60 parts of yam, 15-40 parts of dark plum, 10-30 parts of polygonatum, 10-30 parts of ginkgo, 5-25 parts of raphanus, 0.3-3 parts of fermented bacteria powder and 3.1-13 parts of enzyme preparation. The fermented composition with the function of moistening and nourishing the lung is prepared by the joint action of the fermented bacteria powder and the enzyme preparation on the five main components of the food and medicine.
Owner:江苏菌钥生命科技发展有限公司

Amoxicillin-loaded self-assembled nanoparticles, and preparation method and application thereof

PendingCN122272527ACitrullineOrganic base
This invention discloses amoxicillin-loaded self-assembled nanoparticles, their preparation method, and applications, belonging to the field of biomedical material preparation technology. The preparation method includes the following steps: mixing ginkgolic acid and anhydrous N,N-dimethylformamide, adding a condensing agent, and stirring to obtain a reactant; adding D-citrulline, adjusting the pH to alkaline by adding an organic base, reacting at room temperature, adding ultrapure water to the reaction solution, adjusting the pH to acidic, extracting, collecting the organic phase, washing, drying, filtering, concentrating under reduced pressure, dialysis, and lyophilizing to obtain a ginkgolic acid-D-citrulline conjugate; mixing with a self-assembly carrier material and amoxicillin, forming a nano-dispersion through self-assembly in a solvent system, and lyophilizing to obtain amoxicillin-loaded self-assembled nanoparticles. These amoxicillin-loaded self-assembled nanoparticles have small particle size, good dispersibility, and high stability, which can improve the delivery effect and application performance of amoxicillin in Staphylococcus aureus biofilm-associated infections.
Owner:HUAZHONG AGRI UNIV

Application of macroporous resin assisted ginkgo biloba juice fermented by probiotics in attenuating and enhancing efficacy

ActiveCN116064278BBiotechnologyFruit juice
The application discloses a method for reducing toxicity and increasing efficiency of ginkgo biloba juice fermented by macroreticular resin assisted probiotics, and the strains are ginkgo endogenous lactobacillus, and the names are lactobacillus plantarum TY-HYB-SYY-Y2 and lactobacillus pentosus TY-HYB-SYY-Y3 , and the preservation numbers of the China General Microbiological Culture Collection Center are CGMCC No. 25128 and CGMCC No. 25127 respectively; the macroreticular resin is a macroreticular adsorption resin. The application finds that the ginkgo endogenous lactobacillus can promote the reduction of the content of toxic substances such as ginkgoic acid and ginkgo poison during the fermentation of ginkgo biloba juice, and at the same time, the content of ginkgo lactone is increased, and it is found that the content of ginkgo acid is further reduced during the macroreticular resin assisted fermentation process, and a more obvious reduction effect is achieved.
Owner:NANJING AGRICULTURAL UNIVERSITY

Wuzi kidney-tonifying pill and preparation method thereof

The invention discloses a Wuzi kidney-tonifying pill and a preparation method thereof. The Wuzi kidney-tonifying pill is prepared from the following raw materials in parts by weight: 100g of longspur epimedium, 100g of actinolite, 100g of fructus psoraleae, 100g of rhizoma curculiginis, 150g of sweet potato pulp, 150g of radix morindae officinalis, 150g of radix rehmanniae preparata, 100g of fructus lycii, 100g of mulberry, 100g of semen cuscutae, 100g of rhizoma coptidis, 100g of semen euryales, 100g of semen ginkgo, 200g of herba cistanche and 100g of Chinese chive seeds. Therefore, a traditional formula is upgraded and optimized through the modern pharmacology and process technology, and the whole-process improvement of refined medicinal material treatment, scientific compatibility and intelligent pelleting process is realized. Specifically, longspur epimedium, morinda officinalis, radix rehmanniae preparata, actinolite and other warm kidney-yang-tonifying medicines are introduced into the preparation, meanwhile, Chinese wolfberry fruits, mulberries, semen cuscutae, gordon euryale seeds and other essence-enriching and marrow-filling medicines are matched, the formula covers multiple vitamin paths of tonifying yang, nourishing yin and inducing astringency, and the preparation can better cope with modern sub-health states such as kidney deficiency, immunocompromise and endocrine disorder.
Owner:李乃新

Composition for promoting neutrophil proliferation as well as preparation method and application thereof

The invention discloses a composition for promoting neutrophil proliferation and a preparation method and application thereof. The composition is prepared from the following raw materials in parts by weight: 30-40 parts of gorgon fruit, 10-20 parts of fructus alpiniae oxyphyllae, 10-20 parts of ginkgo, 10-20 parts of hawthorn, 10-20 parts of Chinese yam, 10-20 parts of liquorice, 10-20 parts of poria cocos, 10-20 parts of lotus seed and 10-20 parts of astragalus membranaceus. The traditional Chinese medicine composition completely conforms to the traditional Chinese medicine mechanism and the theory of homology of medicine and food, can tonify spleen and replenish qi, reinforce kidney and arrest seminal emission and clear damp, and has good effect of promoting neutrophile granulocyte proliferation and immune protection effect.
Owner:GUANGDONG INST OF TRADITIONAL CHINESE MEDICINE +1

Separation and purification process of ginkgo compound GK-A

The invention relates to the field of separation and purification of traditional Chinese medicine monomers, in particular to a separation and purification process of a ginkgo compound GK-A. The separation and purification process comprises the following steps: crushing ginkgo kernels, mixing the ginkgo kernels with water, stirring, carrying out solid-liquid separation, and adjusting the pH to be acidic, so as to obtain a macroporous resin loading solution; then loading a sample on a macroporous resin column, washing with water to remove impurities, eluting with a 5-50% ethanol solution, collecting an eluent, adjusting the pH value of the eluent to 6-9, and concentrating to obtain an eluted concentrated solution; mixing the eluted concentrated solution with methanol, adjusting the pH value to be acidic to obtain a prepared sample loading solution, preparing and separating through reversed-phase preparative liquid chromatography, and collecting a GK-A fraction section; carrying out acid removal and column flushing on the GK-A fraction section by adopting reversed-phase preparative liquid chromatography, and collecting column flushing liquid; adding a sodium hydroxide solution into the column flushing liquid to obtain a GK-A solution; and adsorbing and removing impurities by using medicinal carbon, filtering, concentrating and drying to obtain a high-yield and high-purity pure GK-A product.
Owner:INSTITUTE OF CHINESE MATERIA MEDICA CHINA ACADEMY OF CHINESE MEDICAL SCIENCES

Anti-aging, anti-oxidation and blood fat reducing enzyme liquid and preparation method thereof

PendingCN122004455AFood scienceBiotechnologyGinkgo nut
The invention belongs to the technical field of food fermentation, and discloses an anti-aging, anti-oxidation and blood fat-reducing enzyme liquid and a preparation method thereof. The enzyme liquid is prepared by taking 2-5 parts of hawthorn, 2-5 parts of apple, 1-3 parts of lemon, 0.8-1.5 parts of ginkgo and 1.5-2.5 parts of broken rock sugar as main raw materials, supplementing mountain spring water and honey, and performing raw material pretreatment, primary constant-temperature fermentation and secondary constant-temperature fermentation. The ginkgo seeds are boiled to remove toxins, the primary fermentation is carried out at 28-35 DEG C for 60-90 days, and the secondary fermentation is carried out at 25-32 DEG C for 25-35 days. The prepared enzyme liquid is yellowish, transparent and bright and fragrant in smell, has the remarkable effects of resisting oxidation and aging and assisting in reducing blood fat, can improve intestinal flora and whiten skin, and is suitable for auxiliary conditioning of hyperlipidemia, nephritis and abnormal liver function. The invention has the advantages of scientific formula, controllable process, high safety and good stability, and is suitable for industrial production and market promotion.
Owner:SHENZHEN QIANZHIBEN HEALTH MANAGEMENT CO LTD

Polypeptide composition as well as preparation method and application thereof

The invention relates to the technical field of biology, and particularly discloses a polypeptide composition as well as a preparation method and application thereof. The polypeptide composition comprises American ginseng peptide, rhizoma polygonati peptide and ginkgo fruit peptide. The mass ratio of the American ginseng peptide to the rhizoma polygonati peptide to the ginkgo nut peptide is (20-100): (5-15): (20-150). According to the polypeptide composition disclosed by the invention, the specific raw materials are matched, so that the sleep latency period of an insomnia mouse is effectively shortened, the sleep maintenance time of the mouse is prolonged, the content of 5-HT in hippocampal tissues of the mouse is increased, and the effect of improving sleep is achieved. The raw materials used in the polypeptide composition are safe, and the polypeptide composition can effectively assist sleep and improve insomnia for a long time and has a good application prospect.
Owner:CHENGUANG BIOTECH GRP HANDAN CO LTD

Medicine pair composition with effects of relieving cough and reducing sputum, food prepared from medicine pair composition and detection method of food

The invention discloses a medicine pair composition with cough-relieving and sputum-reducing effects and a quality detection method thereof.Ginkgo seeds and Chinese dates are compatible to achieve the effects of reducing toxicity and preserving effects, after the ginkgo seeds and the Chinese dates are compatible, UPLC-Q TOF-MS / MS detection analysis shows that the types and the content of chemical components are changed, compared with a ginkgo seed group, the cough-relieving effect of a compatible group on mice is enhanced, and the cough-relieving effect of the compatible group on the mice is improved. And after the ginkgo seeds are compatible with the Chinese dates, the toxicity of the ginkgo seeds to cerebral nerve cells is improved, and the ginkgo seeds and the Chinese dates can be developed into healthy food through the compatibility of the ginkgo seeds and the Chinese dates.
Owner:NANJING UNIV OF TRADITIONAL CHINESE MEDICINE HANLIN COLLEGE

Pediococcus pentosaceus strain ncu16v with prevention of thrombosis and cerebral ischemic injury, microbial inoculant comprising the same, and use thereof

The application provides a Pediococcus pentosaceus strain NCU16V with thrombus prevention and cerebral ischemic injury prevention, a microbial inoculum containing the same and application, and relates to the technical field of microorganisms.The preservation number of the Pediococcus pentosaceus strain NCU16V is CGMCC No.35427.The Pediococcus pentosaceus strain NCU16V has good gastrointestinal digestion tolerance, and has a high survival rate after being digested in simulated artificial gastric juice and intestinal juice for 3 hours, as verified by the research of the application.Meanwhile, it is verified that the Pediococcus pentosaceus strain NCU16V and the microbial inoculum containing the same can be widely applied in drugs for preventing thrombosis, drugs for relieving brain tissue injury after cerebral ischemia and preparation of ginkgo fermented products with thrombosis prevention.
Owner:NANCHANG UNIV

A method for nondestructive reduction of toxic components in ginkgo nut kernels and products prepared therefrom and uses thereof

The application discloses a method for lossless reduction of toxic components in ginkgo nuts and products and applications prepared by the method. The method comprises the following steps: removing the middle seed coat and inner seed coat of raw ginkgo nuts to obtain raw ginkgo whole kernel; boiling the raw ginkgo whole kernel with water to obtain boiled ginkgo whole kernel; cooling the boiled ginkgo whole kernel and water boiling liquid to room temperature; adding alpha-amylase to the boiled ginkgo whole kernel and water boiling liquid; performing constant temperature water bath after adding the alpha-amylase, filtering out the boiled ginkgo whole kernel to obtain water bath extraction liquid and attenuated boiled ginkgo whole kernel; and recovering 4'-O-methyl pyridoxine and 4'-O-methyl pyridoxine-5'-glucoside in the water bath extraction liquid. The method effectively removes MPN and MPNG in ginkgo nuts, is simple in process operation, is high in safety, and uses only water and heat treatment. The low-toxicity boiled ginkgo whole kernel obtained by the method can be used as raw material of various ginkgo foods, and is particularly suitable for ginkgo foods that need to be cooked with whole kernel.
Owner:SUQIAN COLLEGE

A superhydrophobic, high-strength SiO2 aerogel composite material and its preparation method

This invention discloses a superhydrophobic, high-strength SiO2 aerogel composite material and its preparation method. The method involves esterifying ginkgolic acid with hydroxyl-containing bio-based plant oil under the action of catalyst 1 to obtain a prepolymer intermediate. This prepolymer intermediate is then incorporated into SiO2 sol, and in-situ grafting modification and gelation reactions are carried out under the action of catalyst 2 to form a wet gel. After aging, solvent replacement, and supercritical drying, the target product is obtained. This invention introduces a flexible hydrophobic long-chain crosslinked structure into the three-dimensional SiO2 network through the molecular design of the prepolymer intermediate and the in-situ grafting co-gel process, effectively shielding silanol groups, achieving a water contact angle of over 140°, increasing compressive strength and flexural strength by 70%~500% and 50%~900%, respectively, while maintaining thermal conductivity at 0.019~0.022 W / (m·K), resulting in excellent thermal insulation performance. It uses green and renewable raw materials to replace petroleum-based reagents, and the process is simple and controllable, overcoming the shortcomings of existing aerogels such as strong hydrophilicity, high brittleness, and poor interfacial compatibility, making it suitable for industrial-scale production.
Owner:GUIZHOU AEROSPACE WUJIANG MACHINERY & ELECTRICITYEQUIP

Separation and purification method of ginkgolic acid monomer in ginkgo testa

The invention discloses a method for separating and purifying ginkgolic acid in ginkgo testa, which adopts methanol reflux extraction, ethyl acetate extraction separation, macroporous resin purification and high performance liquid chromatography monomer separation technologies to effectively separate five ginkgolic acid monomers, the purity reaches 98%, and the process verification recovery rate of ginkgolic acid extract reaches 75.76%. The ginkgo biloba exocarp is turned into wealth from waste, the economic value is provided, and the environment is protected. And the method is simple to operate and suitable for industrial production.
Owner:TONGREN POLYTECHNIC COLLEGE

Compound ginkgo dew and preparation method thereof

The invention discloses compound ginkgo dew and a preparation method thereof. The compound ginkgo dew is prepared from the following raw material components: raw material pulp, a stabilizer, an emulsifier, a sweetening agent and water, the compound ginkgo dew is prepared from the following components in percentage by mass: 70%-80% of raw material pulp, 0.1%-0.2% of a stabilizer, 0.1%-0.2% of an emulsifier, 0.01%-0.02% of a sweetening agent and the balance of water. The volume ratio of the ginkgo pulp to the sweet almond pulp to the fructus perillae pulp in the raw material pulp is 1: (0.5-2): (0.5-2). The preparation method comprises the following steps: uniformly mixing ginkgo pulp, sweet almond pulp and fructus perillae pulp to obtain raw material pulp; adding a stabilizer, an emulsifier and a sweetener into the raw material slurry, stirring uniformly, and performing water bath at 60 DEG C for 10 minutes; the compound ginkgo dew is prepared by taking ginkgo kernels, sweet almonds and fructus perillae as core compatibility, the synergistic conditioning of the ginkgo kernels for astringing lung and relieving asthma, the almonds for moistening lung and moistening intestines and the fructus perillae for depressing qi and reducing phlegm is utilized, the compound health-care efficacy of moistening lung, reducing phlegm and moistening intestines is achieved, and the efficacy limitation of a single raw material is broken through.
Owner:XIAN MEDICAL COLLEGE