114results about How to "Meet the requirements of industrial mass production" patented technology

The invention discloses a nutrient release rate adjustable plant oil coated controlled-release fertilizer and a preparation method thereof. The preparation method comprises the following step: base on total weight of a coating frame substances, firstly co-mixing and polymerizing 1-10 percent of a pore-foaming agent, 1-18 percent of a film forming aid paraffin, 0.01-0.6 percent of an organic metal catalyst and plant oil polyol to prepare a coating material A; uniformly and simultaneously spraying the coating material A and polyisocyanate on the surface of a core fertilizer in a rotational flow-spraying fluidized bed on the bottom side; performing an in-situ polymerization reaction to generate a uniform high-molecular coating layer on the surface of the core fertilizer, wherein the coating frame substances are the plant oil polyol and the polyisocyanate of which the weight ratio is 1:(0.5-1.5). The preparation method disclosed by the invention has innovation in coating material selection, coated fertilizer nutrient release performance regulation, coating material co-mixing and polymerization process and coating process; the prepared controlled-release fertilizer is stable in quality, complete in coating, controllable in nutrient release rate, low in energy consumption in the coating process and simple and easy to operate in process.

The invention belongs to the field of metallurgy and particularly relates to a vanalium preparation method. The vanalium preparation method provided by the invention is low in cost and ensures high purity of obtained alloy. The technical scheme provided by the invention is as follows: in the vanalium preparation method, vanadium pentoxide and metallic aluminium are used as raw materials and are subjected to ignition reduction in a reaction device to obtain vanalium and furnace clinker; and a continuous feeding manner is adopted for the reaction device during feeding, and the feeding speed is 5-40kg/min. Compared with the prior art, the vanalium preparation method provided by the invention has the advantages that no coolant is added for controlling heat so that the cost is lower and the requirement for mass industrial production is completely met; and the produced vanalium is low in impurity content, the finished vanalium contains 65-91wt% of V, 9-35wt% of Al, not more than 0.3wt% of Fe and not more than 0.3wt% of Si, and the obtained vanalium has higher purity and meets the requirement of subsequent further processing.

The invention discloses an oral prednisone time-selecting release preparation and a preparation method thereof. The oral prednisone time-selecting release preparation provided by the invention mainly consists of 0.3-5 parts of prednisone and derivatives thereof, 10-50 parts of glyceryl behenate and 3-30 parts of hydroxypropyl cellulose, and can further contain a disintegrating agent and other pharmaceutically acceptable excipients. The preparation method is as below: extruding tablet cores or granules containing the drug according to the formula by a tablet press or a dry granulator; and coating the tablet cores or particles containing the drug by a coating pan or a fluidized bed to attach the coating film to the tablet cores or particles containing the drug, so as to obtain the oral prednisone time-selecting release preparation. The oral prednisone time-selecting release preparation provided by the invention can achieve a good balance between the biological rhythm of the patients and the curative effects, and is safer, more convenient and effective compared with a traditional preparation. The oral prednisone time-selecting release preparation is prepared by an extrusion-coating process, which is simple for operation, and the obtained time-selecting release preparation has the advantages of drug stability and high reproducibility.

The invention relates to a method for preparing metal vanadium, and belongs to the field of metallurgy. The technical problem to be solved is to provide a method for preparing the metal vanadium with low production cost. The method for preparing the metal vanadium comprises the following steps of: a, preparing crude vanadium, namely igniting and reducing vanadium trioxide and vanadium pentoxide serving as raw materials by using Al powder as a reducing agent to obtain the crude vanadium and slag, wherein the weight ratio of the vanadium trioxide to the vanadium pentoxide is 1:1-2, and the using amount of the Al powder is 0.6 to 0.9 time the theoretical using amount of the raw materials when the raw materials are completely reduced into vanadium (V) (the theoretical using amount is the using amount of the Al powder required for completely reducing the vanadium trioxide and the vanadium pentoxide serving as the raw materials into the metal vanadium); and b, refining, namely performing vacuum refining to obtain the metal vanadium.

The invention discloses an enzymatic production technology of chitosan oligosaccharide. The technology comprises steps as follows: a, chitosan is added to an acetate solution, and a chitosan solution is prepared; b, a hydrogen peroxide solution is added to the chitosan solution and stirred uniformly, a mixed solution is subjected to a degradation reaction, and a degraded solution is obtained after degradation; c, the degraded solution is cooled to the room temperature, pH value is regulated to 6.2-6.5, then beta-glucosidase is added for primary enzymolysis, and a primary enzymatic hydrolysate is obtained; d, alpha-1, 4-glucan glucohydrolace is added to the primary enzymatic hydrolysate for secondary enzymolysis, and a secondary enzymatic hydrolysate is obtained; e, pH value of the secondary enzymatic hydrolysate is regulated to 6-6.5, the secondary enzymatic hydrolysate is subjected to rough filtration, ultrafiltration, nanofiltration, spray drying and sterilization sequentially, and a finished chitosan oligosaccharide product is obtained. According to the enzymatic production technology of chitosan oligosaccharide, the yield of chitosan oligosaccharide is greatly increased, molecular weight of the finally prepared chitosan oligosaccharide product can be smaller than 1500, the size is relatively uniform, and besides, the product contains no monosaccharide, therefore, the quality of the chitosan oligosaccharide product is effectively improved.

The present invention discloses the preparation process of nickel-base catalyst for decomposing ammonia. The preparation process includes the following steps: preparing water or alcohol solution of nitrate containing Ni, Al or Zr, with assistant La or Ce being capable of being added into the solution, and preparing stoichiometric water or alcohol solution of ammonium carboanate or ammonium bicarboanate; dropping these two kinds of solution into the same container while controlling the pH of the mixed solution in 7-10; stirring to age after finishing material feeding, separating to eliminate mother liquid, washing the precipitate with deionized water, drying and roasting at 400-900 deg.c to obtain the nickel-base catalyst. The nickel-base catalyst has high catalytic activity and high stability as well as simple preparation process and low production cost.

The invention discloses a preparation method of a cinnamon polyphenol extract. The method comprises the following steps of: extracting cinnamon with ethanol water or acetone water; removing ethanol or acetone in the extracting solution by a reduced pressure distillation method, then adding a proper amount of water and diluting concentrated liquor to obtain crude extract; extracting the crude extract with petroleum ether, diethyl ether or methylene dichloride and collecting a water layer obtained from extraction; and extracting the collected water layer with ethyl acetate, combining an ethyl acetate layer obtained from extraction, removing the ethyl acetate by a reduced pressure distillation method, and drying to obtain solid powder of the cinnamon polyphenol extract. The preparation method is simple, does not need special equipment or complex technological condition, is low in preparation cost, and accords with the requirement of industrial batch production. The content of total polyphenol in the cinnamon polyphenol extract is as high as 30-40wt%, and hypoglycemic drug preparation can be developed so as to sufficiently guarantee application research of the cinnamon polyphenol extract.

The invention discloses a method for refining isosorbide by a distillation and melt crystallization coupling technology. The method comprises the following steps: dehydrated mixed liquor of sorbitol is introduced to a distillation retort for reducing pressure and distilling; low-boiling isosorbide vaporization flows out from the upper part and enters a heat exchanger, high-boiling sorbitol, 1.4-dehydrated sorbitol and other dehydrated products remain at the bottom of a kettle, and are discharged from the bottom of the kettle. Vapor from the upper part enters the heat exchanger by introductionfor heat exchanging and condenses into liquid state after heat is exchanged by the heat exchanger; low-boiling distillate after heat exchanging is directly introduced into a crystallizer for reducingtemperature and crystallizing. The processes of temperature reducing and crystallization are melt crystallization, comprising four steps: hanging membrane, crystallizing, sweating and melting. In theinvention, the distillation and melt crystallization technologies are coupled and adopted to refine the isosorbide, in the melt crystallization process, 3-8 crystallizers are used for cycle use in turn, and the distillation and crystallization can be carried out continuously. The method of the invention has simple operation, less pollution to environment and low power consumption and the like; andthe ultimate purity of isosorbide can reach over 99.5%.

The invention discloses a method for preparing abiraterone acetate. The method comprises the following steps of: (A) carrying out Suzuki coupling reaction on a formula I compound and 3-pyridineboric acid or a 3-pyridineboric acid derivative in a mixed solvent formed by an organic aprotic solvent and water under the action of a metal palladium catalyst and alkali; (B) after the reaction is finished, adding ethyl acetate and the water to a reaction system for liquid separation; collecting organic phases, sequentially washing by using the water and a saturated salt solution, drying and concentrating to obtain an oily crude product; (3) adding a crystallizing solvent to the oily crude product, and stirring for crystallization; (D) collecting solids for recrystallization. The method disclosed by the invention has the advantages of simple process, low cost and easiness for obtaining of raw materials, easiness for purifying treatment, high yield, low cost, high finished product purity, and the like, completely meets the requirement for industrialized batch production and has very high practical value.

The invention provides an efficient fiber-based thermoelectric energy supply material and a preparation method thereof. The efficient fiber-based thermoelectric energy supply material comprises a fiber-based self-generating layer and a photo-thermal film arranged on an upper surface of the fiber-based self-generating layer, wherein the fiber-based self-generating layer is prepared by dipping the fiber base material in the thermoelectric solution and then arranging the electrodes on the upper surface and the lower surface of the dipped and dried fiber base material; and a colloidal photo-thermal material formed by mixing photo-thermal nanoparticles and a viscose solution is coated on the upper surface of the fiber-based self-generating layer to form the photo-thermal film. The material is advantaged in that the temperature of the upper surface of the fiber-based self-power-generation layer is increased through molecular thermal motion generated after the photo-thermal film absorbs solarrays and infrared rays emitted by a human body, a temperature difference is formed between the fiber-based self-power-generation layer and the lower surface of the fiber-based self-power-generation layer, the thermoelectric material is driven to generate voltage, and the self-power-generation function is achieved; and the efficient fiber-based thermoelectric energy supply material is excellent inthermoelectric performance, high in power generation efficiency and good in flexibility, and has relatively high application value.

The invention relates to a transition metal phosphide MxPy oxygen reduction and hydrogen evolution bifunctional catalyst and a preparation method and application thereof. The preparation method comprises the following steps: S1, mixing transition metal elementary substance M and red phosphorus powder, and ball milling to obtain transition metal phosphide MxPy material in an inert atmosphere; S2, adding a dispersing agent into the MxPy material, ball milling, and drying to obtain a transition metal phosphide MxPy bifunctional catalyst for oxygen reduction and hydrogen evolution. A metal transition phosphide with high purity, small crystal grain size and large specific surface area is prepared by a ball milling method, and has excellent ORR and HER catalytic performance and high stability, and can be widely applied to metal-air batteries, fuel cells or electrocatalytic hydrolysis to produce hydrogen; and the preparation method provided by the invention is simple and quick, the raw materials are cheap and easy to obtain and pollution-free, the production cost is low, and the requirement of industrialized mass production is met.

The invention is a chitooligosaccharide/chito oligomer production process by specific enzyme, firstly preparing 1-6% chitosan solution, adding in saturated sodium bicarbonate solution to regulate pH value, adding in endo-chitosanase for enzymic hydrolysis, then adopting macroporous weakly acidic cation resin chromatographic column to separate and purify the degraded product- chitooligosaccharide, and after reaction ends, adopting screen filter method to recover immobilized enzyme, adopting ultrafiltration membrane to recover dissociative enzyme, and able to use repeatedly. And the process can make high efficiency specific degradation on chitosan, extremely raising yield of chitooligosaccharide, having featuring of simple production process, largely reduced production cost, and effectively improved quality of chitooligosaccharide product. And the whole production process is a continous production process, which meets the requirements for industrialized large-scale production of chitooligosaccharide product.

The invention belongs to the technical field of numerical control engraving, and discloses a numerical control laser engraving machine, a control system, a control method and a computer. The control method comprises the steps that a set of circularly photographing graph sequences are obtained through a camera through a CAD graphic module, so that CAD engraving graphic data of a to-be- engraved product is obtained; moreover, the data are preprocessed through a signal processor and then are sent to a graphic processing module for analysis of the CAD engraving graphic data of the to-be-engraved product; the analyzed data is input into a single-chip microcomputer to be compiled by an engraving program; and an instruction of the compiled program is sent to a core board module, an instruction motor drives a laser to slide back and forth in a guide rail, and engraving of the whole graph is completed. According to the numerical control laser engraving machine, the control system, the control method and the computer, fine engraving can be carried out by utilizing laser, a computer numerical control technology is used and can be well combined with a laser processing system so that requirements for industrial mass production can be met, the production efficiency can be effectively improved, moreover, by using laser processing, the environment can be prevented from being polluted, and thepracticability and the generalization performance are good.

The invention relates to the technical field of thermoplastic processing of polyvinyl alcohol, and concretely relates to a modification method of polyvinyl alcohol capable of being subjected to thermoplastic processing. The method comprises the following steps: (a) performing molecular modification: mixing a polyhydroxy small molecular compound with an aqueous polyvinyl alcohol solution to form ahomogeneous solution; and (b) performing physical modification: cooling the homogeneous solution in step (a) to form an ice crystal mixture, and freeze-drying the ice crystal mixture. The polyvinyl alcohol is firstly subjected to molecular modification, and then is subjected to physical modification, and molecular modification and physical modification are combined to achieve synergistic effects,so the melting temperature of the polyvinyl alcohol is reduced greatly, and meanwhile, the temperature interval of melting processing is increased, thereby the polyvinyl alcohol is conveniently subjected to melting processing to prepare various profiles, such as pipes.

The invention relates to the technical field of reutilization of threonine mother liquor, in particular to feed with the threonine mother liquor as a raw material and a preparation method of the feed.The threonine mother liquor produced by a fermentation method is used as the raw material, a multi-effect evaporator is used for evaporating and concentrating the threonine mother liquor, then concentrated mother liquor is mixed with auxiliary materials according to different proportions, and a mixture is processed by spray-drying or slurry-spraying granulation equipment to obtain the feed; and the obtained feed has the moisture content of less than 5%, good product flowability and no caking. The method solves the problem that the threonine mother liquor cannot be granulated due to too high viscosity in the prior art, avoids the problem of waste or pollution caused by discarding or burning the threonine mother liquor, is simple, and can meet the requirements of industrial mass production.

The invention discloses a vanadium-aluminum alloy production method, and belongs to the technical field of metallurgy. The technical effects that the rate and quality of finished products of vanadium-aluminum alloy are improved, the impurity content of the vanadium-aluminum alloy is reduced, the production scale of the vanadium-aluminum alloy is broadened, and the cost of the vanadium-aluminum alloy is reduced are achieved. The vanadium-aluminum alloy production method comprises the steps that the first batch of vanadium oxide and the first batch of aluminum are added into a graphite crucibleprovided with a drilled cover, ignition is conducted for aluminothermic reduction reaction, after reaction is completed, the follow-up batch of vanadium oxide and the follow-up batch of aluminum are added in sequence, aluminothermic reduction reaction is conducted till all vanadium oxide and aluminum are added and reacted completely, slag is separated from the alloy, and the vanadium-aluminum alloy is obtained. According to the method, the batched adding mode is adopted, the graphite crucible provided with the drilled cover is used as a smelting furnace body, the production scale is expanded,the vanadium yield is increased, a slagging cooling agent does not need to be added, the cost is lower, the obtained alloy is higher in purity and quality, and the industry large scale production requirements are completely met.