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19results about How to "Clear composition" patented technology

Feed additive for preventing broiler necrotic enteritis, preparation method and application

The invention discloses a feed additive for preventing broiler necrotic enteritis, a preparation method and application, and relates to the technical field of feed. Comprising the following raw materials in parts by weight: 15-30 parts of plant essential oil, 40-60 parts of deoxycholic acid, 10-20 parts of vitamin D310, 3-8 parts of protein zinc, 2-6 parts of saccharomyces cerevisiae and 1-5 parts of zeolite powder. The feed additive provided by the invention is clear in component, stable in property, convenient to operate and control, easy to realize industrial production, and convenient to popularize and apply. By adopting the feed additive provided by the invention, the integrity of the intestinal epithelial barrier can be improved, the intestinal flora structure can be improved, the immunity of the organism can be improved, and necrotic enteritis of broilers can be effectively prevented.
Owner:INST OF ANIMAL SCI & VETERINARY HUBEI ACADEMY OF AGRI SCI

Homogeneous coated fiber material based on electrostatic-air jet coaxial spinning and preparation method thereof

The present invention discloses a homogeneous coating fiber material based on electrostatic-jet coaxial spinning and a preparation method thereof, wherein the homogeneous coating fiber material based on electrostatic-jet coaxial spinning includes a core layer located inside and a cortex layer arranged outside the core layer; the material of the core layer includes at least one of degradable polyurethane (BPU) and degradable polyester (BPE); the material of the cortex layer includes a water-soluble polymer matrix, a functional compound molecule, and a cross-linking agent; the functional compound molecule includes at least one compound molecule of anticoagulation, anticalcification, antioxidation, antiproliferation, and anti-infection. The present invention adopts homogeneous blending technology to prepare a spinning solution, and then spins a uniform skin-core structure fiber through a special electrostatic-jet coaxial spinning nozzle, and then soaks in a dilute solution of a green cross-linking agent, ultrasonically washes, pre-freezes, and vacuum freeze-dries to obtain a highly efficient functionalized fiber of the finely controlled coating.
Owner:SHANGHAI UNIV OF ENG SCI

Method for analyzing and identifying squalene ozonation gas phase and particle phase products

The invention belongs to the technical field of biomedicine in the aspect of human health, and particularly relates to a method for analyzing and identifying squalene ozonation gas-phase and particle-phase products. The method specifically comprises the following steps: firstly, introducing ozone with a certain concentration into a sampling bag, and then injecting a squalene standard solution, so that squalene reacts with the ozone; then, a proton transfer reaction time-of-flight mass spectrometer (PTR-TOF-MS) is used for collecting and analyzing the composition and concentration of a gas phase product of the reaction, and an aerosol chemical component real-time analysis sample introduction system (CHARON) is used for collecting and analyzing the composition and concentration of a particle phase product of the reaction in combination with the PTR-TOF-MS. According to the method, the gas-solid distribution characteristic research of the squalene ozonation product can be perfected, and a reference basis is provided for the research of indoor peculiar smell and indoor environment health effect.
Owner:GUANGDONG UNIV OF TECH

Human amniotic fluid source organoid in-vitro culture medium, in-vitro culture method and application

The invention relates to an in-vitro culture medium, an in-vitro culture method and application of a human amniotic fluid source organoid. The in-vitro culture medium of the human amniotic fluid source organoid comprises a DMEM-F12 basal culture medium, a glial cell source neurotrophic factor, 8-bromoadenosine-3 ', 5'-cyclic monophosphate and aldosterone. The culture medium provided by the invention is clear in component and high in culture success rate. The human amniotic fluid organ cultured by using the culture medium and the method disclosed by the invention can be differentiated into multiple types of functional cells including neuron-like cells, myocardial cells and the like through in-vitro induction, and the differentiation capacity is obviously superior to that of an existing 2D cell line model.
Owner:REIN CELL ENG TECH (GUANGZHOU) CO LTD

Cinnamomum camphora flavone component with anti-aging effect as well as preparation method and application of Cinnamomum camphora flavone component

The invention discloses a flavonoid component of Cinnamomum camphora and a preparation method and application thereof, and relates to the technical field of extraction of functional components of plants with homology of medicine and food, and the preparation method mainly comprises the following steps: analysis and definition of the flavonoid component, extraction and refining of the flavonoid component, and analysis and application of the anti-aging effect of the flavonoid component. The yield and the content of the flavonoid components of the Cinnamomum camphora Bunge prepared by the method are high; the preparation process is high in specificity, and the method has the characteristics of high preparation efficiency, high sample yield, no emission of toxic and harmful reagents and the like; the obtained flavonoid component is clear in composition and has a good anti-aging effect. The invention establishes the preparation method of the antrodia camphorata flavone component with the anti-aging effect, the antrodia camphorata flavone component is practically applied to a nematode model, the antrodia camphorata flavone component has anti-aging potential, and a technical support can be provided for deep research on the anti-aging effect of antrodia camphorata flavone compounds, development of novel functional foods and research and development of new drugs.
Owner:赣江中药创新中心

A high-purity ferrous sulfate solution prepared from waste acid, ferrous sulfate heptahydrate and a method for preparing the same

PendingCN122685130AReduce particle size dispersionReduce morphology fluctuations
The present application belongs to the field of waste acid resource utilization and inorganic salt preparation, and provides a high-purity ferrous sulfate solution, ferrous sulfate heptahydrate and a preparation method thereof from waste acid. The present application forms a supersaturated crystallization feed by adjusting the iron-containing waste acid feed liquid, separately prepares plate-shaped ferrous sulfate heptahydrate directional seed A1-S, and crystallizes under low-dissolved oxygen conditions. Then, the wet crystal is subjected to micro-dissolution and recrystallization treatment in an acid sulfate system by using a ferrous-rich sulfuric acid surface polishing liquid B2-L. The crystal morphology is stable, the impurity entrainment is reduced, the ferrous valence is maintained, and the mother liquor circulation is stable. The problems of directional crystallization and purity improvement, low-oxygen control and mother liquor recycling are solved. The present application is suitable for waste acid resource utilization and preparation of high-purity ferrous sulfate products.
Owner:HUIZHOU SIRUIER ENVIRONMENTAL TECH CO LTD

Probe combination, chip, kit and method for detecting eutothrix cyanobacteria strains producing microcystin

PendingCN121951090AReflects synthesis abilityclear compositionNucleotide librariesMicrobiological testing/measurementMicrobiologyAnabaena
The invention discloses a probe combination, a chip, a kit and a method for detecting a floating hylothrix blue-green algae strain for producing microcystin. The floating hylothrix blue-green algae strain capable of producing the microcystic toxins comprises at least one of nine strains, and a probe combination comprises at least one of a probe group SEQ ID No.1 to 10, a probe group SEQ ID No.1 to 10, a probe group SEQ ID No.11 to 20, a probe group SEQ ID No.21 to 30, a probe group SEQ ID No.31 to 40, a probe group SEQ ID No.41 to 50, a probe group SEQ ID No.51 to 60, a probe group SEQ ID No.61 to 70, a probe group SEQ ID No.71 to 80 and a probe group SEQ ID No.81 to 90. The probe combination-based method for detecting the microcystin-producing floating hylothrix blue-green algae strain has the characteristics of fast time efficiency, high accuracy and high sensitivity through chip probe specific hybridization.
Owner:SHENZHEN WATER GRP CO LTD +2

Lycium barbarum protein for regulating oxidative stress caused by exercise fatigue and preparation method of lycium barbarum protein

PendingCN119661627Aclear compositionuniform compositionPeptide preparation methodsFood scienceBiotechnologyFruit Proteins
The invention discloses a medlar protein for regulating oxidative stress caused by exercise fatigue and a preparation method thereof, and belongs to the technical field of processing of food / agricultural products and byproducts thereof. According to the method, fresh Chinese wolfberry fruits are pulped and then subjected to slit-shaped ultrasonic strengthening treatment to obtain raw pulp, and the prepared Chinese wolfberry fruit protein exhausts swimming exercise fatigue oxidative stress model mice through oral administration and intragastric administration, so that the exercise fatigue can be recovered by effectively adjusting oxidative stress caused by the exercise fatigue. The lycium barbarum protein, subunit composition and amino acid composition prepared by the method are clear, the amino acid composition is reasonable, and the lycium barbarum protein can be applied to various recovery products for different types of exercise fatigue oxidative stress, such as various sports drinks, snacks and other supplementary foods in any processing form.
Owner:JIANGSU UNIV

Active peptide capable of directionally inducing IPSCS cracking, preparation method of active peptide and application of active peptide in preparation for repairing liver injury

PendingCN122080139Aefficient releaseClarify the functional characteristics of the liver systemPeptide/protein ingredientsDigestive systemAntioxidative stressEfficacy
The invention discloses an active peptide capable of directionally inducing IPSCS cracking, a preparation method of the active peptide and application of the active peptide in a preparation for repairing liver injury. Experiments prove that the active peptide provided by the invention has a remarkable protective effect on a liver injury model induced by cyclophosphamide and shows a definite anti-oxidative stress effect. The result shows that a key path of chemotherapy injury can be intervened from the source by simulating or enhancing an endogenous protection mechanism of the liver. Compared with the existing exogenous synthetic drugs or single-component natural products, the product provided by the invention has the potential advantages of more comprehensive action mechanism and better biogenic property. Meanwhile, the extract is derived from directionally differentiated functional cells, and a brand new thought and material basis are provided for developing a novel chemotherapy liver protective agent which does not affect the chemotherapy curative effect and has good biocompatibility.
Owner:耿雪璐

Preparation method of hovenia dulcis thunb active component extract with liver protection effect as well as obtained product and application of hovenia dulcis thunb active component extract

The invention belongs to the field of biological medicine, and relates to a hovenia dulcis thunb extraction process, in particular to a preparation method of a hovenia dulcis thunb liver-protecting active component extract with a liver-protecting effect, an obtained product and application. According to the hovenia dulcis thunb extract provided by the invention, active components with specified components can be more efficiently obtained by adopting a two-dimensional high-throughput separation analysis technology; according to the method, the flavonoid components in the hovenia dulcis thunb crude extract are accurately obtained, the content of the flavonoid components is larger than 80%, the extraction time is shortened by 60%, and manpower and reagent use are saved. The hovenia dulcis thunb active component obtained by the method provided by the invention is clear in substance composition, high in extraction rate of flavonoid components and obvious in biological activity in liver protection, and in-vitro cell experiments prove that the hovenia dulcis thunb extract can obviously reduce the ROS level of cells, improve the survival rate of the cells and obviously reduce the ALT and AST levels in cell supernatant. The hovenia dulcis thunb active component extract prepared by the invention lays an experimental foundation for developing a new drug for treating alcoholic liver diseases.
Owner:SHANDONG ACAD OF CHINESE MEDICINE

Carbon-coated pre-magnesium silicon monoxide negative electrode material and preparation method thereof

The invention discloses a carbon-coated pre-magnesium silicon monoxide negative electrode material and a preparation method thereof, the negative electrode material comprises a silicon core, a silicon-magnesium composite porous layer and a carbon-coated layer, the silicon-magnesium composite porous layer comprises MgSiO3 and Mg2SiO4 with porous characteristics, and the porosity is not less than 30%; the material shows a unique peak position and intensity relationship in an XRD diffraction pattern, and Mg2SiO4 is used as a main phase. According to the preparation method, through molten salt mediated low-temperature solid-phase reaction and addition of reducing gas during heat treatment, energy consumption is greatly reduced, a generated Mg2SiO4 crystal structure is more stable than traditional MgSiO3, and a porous structure (porosity is larger than 30%) formed through the cooperation reaction enables the material to maintain high capacity of 1621.49 mAh / g, meanwhile, the first efficiency is improved to 85.91%, and the cyclic expansion rate is reduced by 40% or above.
Owner:CNBM ZHEJIANG MATERIAL TECH CO LTD

Application of verbena glycoside in treating diabetes and / or diabetic complications

ActiveCN116139160BImproves glucose tolerance levelclear compositionOrganic active ingredientsMetabolism disorderDiabetic heartDiabetic complication
The present invention provides the use of verbena glycoside in the preparation of a drug for treating diabetes, the use of verbena glycoside in the preparation of a drug for treating diabetic heart disease, and the use of verbena glycoside in the preparation of a drug for treating diabetic nephropathy. The present invention has found for the first time through research that verbena glycoside has the effect of preventing and treating diabetes and diabetic heart and kidney damage: in terms of blood sugar, verbena glycoside can improve the glucose tolerance level by improving the blood sugar metabolism level; in terms of heart damage caused by diabetes, verbena glycoside can improve cardiac dysfunction and left ventricular remodeling, and inhibit the fibrosis of heart tissue; in terms of kidney damage, verbena glycoside can improve the level of kidney function and inhibit the level of kidney fibrosis. The present invention provides a strong experimental basis and theoretical basis for the use of verbena glycoside in the prevention and treatment of diabetes and its heart and kidney damage, and broadens its application prospects.
Owner:THE FIRST AFFILIATED HOSPITAL OF GUANGZHOU UNIV OF CHINESE MEDICINE

A method for preparing fine components and monomer compounds of Calyx tenuifolia and application thereof in cosmetics

The present invention belongs to the technical field of cosmetics, and specifically discloses a fine-leaved calyx flower extract and its application in the preparation of cosmetics, wherein the extract refers to fine-leaved calyx flower refined components and 7 monomer compounds. The refined components are the components with the strongest antioxidant activity, tyrosinase inhibition activity and matrix metalloproteinase inhibition activity in fine-leaved calyx flower; the 7 monomer compounds are obtained by macroporous resin column chromatography, methanol-water gradient elution, hydroxypropyl dextran gel column chromatography, octadecylsilane bonded silica gel column chromatography, and high performance liquid chromatography acetonitrile water gradient elution of the ethanol extract of fine-leaved calyx flower. The fine-leaved calyx flower extract of the present invention can be applied to skin anti-oxidation, whitening and anti-aging, and is further used to prepare a cosmetic composition containing the extract.
Owner:SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES

Composition with hypoglycemic activity and preparation method and application thereof

The invention provides a composition with hypoglycemic activity and a preparation method and application thereof, and belongs to the technical field of biological medicine. According to the composition disclosed by the invention, cinnamon, turmeric and red ginseng which are homologous in medicine and food are used as core raw materials and are compounded with eggshell membrane extract; after scientific components in parts by weight, all the raw materials achieve synergistic interaction, the inhibition rate on alpha-glucosidase can be remarkably increased, hyperglycemia model rat tests prove that the composition can remarkably reduce the blood sugar concentration, zebra fish tests prove that the composition can remarkably reduce the insulin content and the glucose level, the blood sugar reducing effect is remarkable, and the composition is suitable for clinical application. The traditional Chinese medicine composition can be effectively applied to blood sugar reduction and diabetes treatment. The composition is simple in component, clear in composition, high in raw material safety and free of toxic and side effects, the risk of liver injury possibly caused by combination of multiple traditional Chinese medicines is effectively avoided, and the medication safety and patient compliance are greatly improved.
Owner:JIANGSU ALAND NOURISHMENT

Method for extracting and analyzing palmitic acid in pepper essential oil

The invention discloses a method for extracting and analyzing palmitic acid in pepper essential oil, and belongs to the technical field of food detection.The method comprises the steps that S1, processed black pepper particles and processed white pepper particles are obtained, the prepared black pepper particles and the prepared white pepper particles are smashed respectively, and black pepper powder and white pepper powder are obtained; s2, water and steam are added into the black pepper powder and the white pepper powder for distillation, after distillation is completed, an essential oil layer is taken, and white pepper essential oil and black pepper essential oil are obtained; and S3, respectively adding a petroleum ether extracting solution into the essential oil for extraction, adding a potassium hydroxide and methanol mixed solution for methyl esterification, adding ultrapure water, centrifuging, taking supernatant, filtering, diluting the filtered sample with chromatographic-grade normal hexane, and detecting the content of palmitic acid by using a gas chromatograph-mass spectrometer. According to the method disclosed by the embodiment of the invention, the composition of special effective substances of the pepper essential oil is determined by researching a pepper essential oil palmitic acid component detection technical method, and an important basic technical support is provided for research, development and application of pepper high-quality products in China.
Owner:TROPICAL CORP STRAIN RESOURCE INST CHINESE ACAD OF TROPICAL AGRI SCI

Safety protection platform and method for shuttle vehicle

The invention discloses a safety protection platform and method for a shuttle vehicle, and relates to the field of logistics warehousing system transportation equipment.The safety protection platform comprises a shuttle vehicle operation area used for providing an area for normal work of the shuttle vehicle, and the shuttle vehicle operation area comprises the shuttle vehicle, a maintenance vehicle and an operation track; the maintenance area is an area where the shuttle vehicle is driven by the maintenance vehicle to stop when the shuttle vehicle breaks down and is separated from the shuttle vehicle running area, the maintenance area and the running area are independent, normal running of other devices can be guaranteed while safety is improved, the production efficiency is not affected, the maintenance vehicle adopts the double-station maintenance vehicle, the maintenance time is shortened, and the maintenance cost is reduced. And the transition rail is matched to be connected with the running rail, so that the normal work of the running rail is not influenced in the maintenance process, the composition is clear, the function is clear, and the linkage and safety in the application process are high.
Owner:YUNNAN KSEC INTELLIGENT EQUIP

Fermentation medium and its application in the preparation of teriparatide

The present invention provides a fermentation medium and its application in the preparation of teriparatide, belonging to the field of biopharmaceutical technology. The fermentation medium comprises the following components: yeast peptone, yeast extract powder, dipotassium hydrogen phosphate trihydrate, potassium dihydrogen phosphate, ammonium sulfate, magnesium sulfate heptahydrate, glycerol, trace element solution, defoamer, and the solvent is pure water. The trace element solution added to the fermentation medium of the present invention controls the type and amount of trace elements to obtain a medium that is more conducive to the expression of inclusion bodies. In addition, the strategy of starting at a fixed time point and adjusting the feed flow rate is adopted during the fermentation process, thereby improving the stability of fermentation production.
Owner:YIFAN PHARMACEUTICAL (SHANGHAI) CO LTD

High-efficiency full-automatic multi-gripper type loader

The application provides a high-efficiency full-automatic multi-gripper loader, and belongs to the field of conveying, stacking, loading and logistics machinery. The problem of how to provide a more automatic and high-efficiency loading equipment is solved. The loader comprises a mobile conveying unit, a channeling unit, a grouping unit and a loading unit, the mobile conveying unit, the channeling unit and the grouping unit are sequentially connected, and the grouping unit is invertedly hung on the loading unit. The loading unit is internally provided with a whole lifting mechanism, so that the height of the whole loading unit can be adjusted according to the height of a loading carriage and the height of a top layer of loading bags in real time during a loading operation, the Z-axis stroke of the lifting mechanism is minimized during the loading process, and the loading efficiency is improved.
Owner:HARBIN BOSHI RUBBER & PLASTIC EQUIP CO LTD