The invention provides a composition with hypoglycemic activity and a preparation method and application thereof, and belongs to the technical field of biological
medicine. According to the composition disclosed by the invention, cinnamon, turmeric and red
ginseng which are homologous in
medicine and food are used as core raw materials and are compounded with
eggshell membrane extract; after scientific components in parts by weight, all the raw materials achieve synergistic interaction, the inhibition rate on alpha-
glucosidase can be remarkably increased, hyperglycemia model rat tests prove that the composition can remarkably reduce the
blood sugar concentration, zebra fish tests prove that the composition can remarkably reduce the
insulin content and the glucose level, the
blood sugar reducing effect is remarkable, and the composition is suitable for clinical application. The
traditional Chinese medicine composition can be effectively applied to
blood sugar reduction and
diabetes treatment. The composition is simple in component, clear in composition, high in
raw material safety and free of toxic and side effects, the risk of
liver injury possibly caused by combination of multiple traditional Chinese medicines is effectively avoided, and the medication safety and
patient compliance are greatly improved.