41 results about "Dipsacus asper" patented technology

The invention relates to the technical field of teasel breeding, and discloses a teasel germplasm resource multi-character collaborative screening breeding method, which comprises the following steps: multi-omics data acquisition: extracting teasel germplasm leaf DNA (deoxyribonucleic acid), and capturing exon regions of disease resistance and metabolism related genes by adopting a targeted sequencing technology to obtain an SNP (single nucleotide polymorphism) marker matrix; the method comprises the following steps: collecting root extracts, detecting medicinal components through ultra-high performance liquid chromatography-mass spectrometry, and constructing a metabolite abundance matrix; measuring phenotype data of plant height, root length, root weight, root rot morbidity and survival rate under drought stress; key site and metabolite correlation analysis: constructing a Bayesian network containing SNP markers, metabolite and phenotypes by using a graph database, and carrying out cross validation through a leave-one-out method. The dipsacus asper germplasm resource multi-character collaborative screening breeding method aims at solving the problem that a traditional breeding method lacks systematic integration analysis of genomes and metabolic pathways in dipsacus asper multi-character collaborative improvement.

The invention discloses a traditional Chinese medicine mixture with a liver and kidney tonifying effect and a preparation method thereof, and belongs to the field of pharmaceutical preparations. The traditional Chinese medicine mixture comprises the following components in parts by weight: 45-60 parts of polygonum multiflorum; 45-60 parts of rhizoma polygonati; 110 to 130 parts of fructus rosae laevigatae; 2.4 to 3.2 parts of Chinese angelica; 45-60 parts of rhizoma cibotii; 3.2 to 3.8 of semen cuscutae; 1.8-2.4 parts of dried orange peel; 3.5 parts of fructus psoraleae; the preparation method of the traditional Chinese medicine mixture comprises the following steps: decocting the components in water, filtering, concentrating filtrate until the density is 1.10-1.16 g / mL, adding ethanol until the alcohol content is 60%, standing for 24 hours, taking supernate, filtering, and recovering the filtrate under reduced pressure until no alcohol exists; adding water to 120 parts by weight, adding 2 parts by weight of talcum powder and 1 part by weight of sodium benzoate, uniformly stirring, and standing for 24-48 hours; taking supernatant liquid, adding 120-150 parts by weight of cane sugar, adding water to 300-350 parts by weight, uniformly stirring, boiling, standing and filtering to obtain filtrate, namely the product mixture. Eight medicines of the traditional Chinese medicine mixture are applied dialectically, and complement each other in tonifying liver and kidney, invigorating spleen and replenishing qi, arresting seminal emission and arresting enuresis.

The present invention relates to the technical field of traditional Chinese medicine, and provides a Chinese medicine composition for treating skin lesions and scars, and a preparation method and application thereof, which is mainly used to treat skin lesions and scars caused by carbuncle and ulcer. The Chinese medicine composition of the present invention comprises the following raw materials: Vaccaria segetalis, Astragalus membranaceus, Bletilla striata, Morus alba bark, Angelica dahurica, White Ampelopsis Root, Dictamni Cortex, Rhizoma Cyperi, Rhizoma Bletillae, Bletilla striata Rhizoma, Bletilla striata Rhizoma, Bletilla striata Rhizoma, Bletilla striata Rhizoma, Bark of Bombyx batryticatus, Magnolia officinalis, Pueraria root, Eucommia bark, Dipsacus asper, Smilax glabra, Honeysuckle vine, Chuanxiong, Angelica sinensis, Ephedra sinica, and Cinnamomum cassia. The Chinese medicine composition of the present invention has the effects of dispelling wind and relieving itching, relieving swelling and relieving pain, promoting pus and detoxifying, and reducing color and eliminating scars. It is mainly used to treat skin lesions and scars caused by carbuncle and ulcer, and is significantly effective for treating skin ulcers, swellings, and furuncles. It also treats pruritus caused by deep infected wounds and psoriasis lesions, and reduces the use of antibiotics.

The invention discloses qi-tonifying and bone-strengthening pills and a preparation method thereof, and belongs to the technical field of bone fracture pills. The qi-tonifying and bone-strengthening pill is prepared from the following raw materials: semen cuscutae, herba epimedii, cynomorium songaricum, salted radix dipsaci, scalded rhizoma drynariae, radix polygoni multiflori preparata, radix rehmanniae preparata, fructus lycii, wine-processed glossy privet fruit, herba ecliptae, raspberry, deer-horn glue, tortoise-shell glue, radix astragali preparata, radix angelicae sinensis, radix salviae miltiorrhizae, rhizoma dioscoreae, pericarpium citri reticulatae, fried semen ziziphi spinosae and radix glycyrrhizae preparata. The preparation method of the qi-tonifying and bone-strengthening pill comprises the following steps: adding water into the scalded rhizoma drynariae, and decocting; respectively crushing semen cuscutae, fried spina date seeds and dried orange peel; decocting the raw materials except deer-horn glue and tortoise-shell glue with the crushed semen cuscutae and fried spina date seeds in water, and concentrating the filtrate; and melting deer-horn glue and tortoise-shell glue in the concentrated liquid medicine, adding the crushed dried orange peel and a proper amount of refined honey, uniformly stirring, pelleting and drying to obtain the medicine. The qi-tonifying and bone-strengthening pill is mainly used for treating liver and kidney deficiency type arthralgia, poor rehabilitation in the later period of fracture and other symptoms, and has the functions of tonifying kidney and qi, and strengthening bones and promoting reunion of tendons.

The invention discloses a traditional Chinese medicine composition for treating lumbago and application of the traditional Chinese medicine composition. Rehmannia glutinosa, astragalus membranaceus and radix puerariae are used as monarch drugs; black prepared common monkshood daughter root, dried ginger, cassia twig, asarum, pseudo-ginseng, safflower and the like are used as ministerial drugs; gleditsia sinensis lam, semen brassicae, radix scutellariae, fructus arctii, radix paeoniae alba, fructus lycii, rhizoma atractylodis macrocephalae and the like are used as adjuvant drugs, radix bupleuri, cudrania cochinchinensis, radix dipsaci, eucommia ulmoides, herba epimedii and cynomorium songaricum are used as adjuvant drugs, radix bupleuri is used for soothing liver and regulating qi, and lifting qi to strengthen yang and warm qi, cudrania cochinchinensis is used for promoting blood circulation to remove meridian obstruction, and radix puerariae is used for relieving muscles and relaxing tendons and removing stasis and removing food retention. The traditional Chinese medicine can effectively treat kidney-yang deficiency type and complex lumbago (such as lumbar muscle degeneration, lumbar disc herniation and osteoarthritis), such as cold-dampness stasis and the like, treats both symptoms and root causes, and is not easy to relapse.

The present invention provides a method for preparing bone augmentation and reduction, and belongs to the technical field of traditional Chinese medicine preparations. The raw materials of the bone augmentation and reduction include: Radix Rehmanniae Preparata, Rhizoma Epimedii, Caulis Spatholobi, Cibotium Barbarum, Rhizoma Drynariae, Cynomorium Songaricum, Dipsacus Asper, Fructus Lycii and Semen Raphani; the method includes: choline salt, 1-octyl-3-methylimidazolium bromide and acid hydrogen bond donor or alcohol hydrogen bond donor are heated and mixed to prepare multi-component deep eutectic solvent A or multi-component deep eutectic solvent B; Radix Rehmanniae Preparata powder, multi-component deep eutectic solvent A and water are evenly mixed, and microwave heating is performed to obtain Radix Rehmanniae Preparata extract and Radix Rehmanniae solid residue; the Radix Rehmanniae solid residue after drying, the remaining raw material powder and the multi-component deep eutectic solvent B are mixed with the alcohol solution, and an extraction supernatant is obtained by short-term multiple ultrasonic-assisted extraction; the Radix Rehmanniae Preparata extract and the extraction supernatant are combined and concentrated to obtain a bone augmentation and reduction stock solution; and a bone augmentation and reduction preparation is prepared. The present invention can quickly and efficiently extract the effective active ingredients of each raw material of bone augmentation and reduction, and the conditions are mild and the time consumption is short.

The invention discloses a pharmaceutical composition for treating corpus luteum insufficiency type infertility as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The technical problem to be solved is to provide the pharmaceutical composition for treating the LPD type infertility, which is simpler in formula, lower in cost and better in treatment effect. According to the technical scheme, the pharmaceutical composition is prepared from the following raw materials: codonopsis pilosula, astragalus membranaceus, fried rhizoma atractylodis macrocephalae, angelica sinensis, semen cuscutae, fried eucommia ulmoides, fried teasel root, honey-fried licorice root, processed radix aconiti carmichaeli and cornu cervi degelatinatum. The pharmaceutical composition provided by the invention can improve ovarian injury, ferroptosis phenomenon, embryo implantation disorder, uterine artery blood perfusion and the like caused by LPD, and is helpful for various pathological problems related to LPD.

The invention is suitable for the field of traditional Chinese medicines, and provides a traditional Chinese medicine decoction for treating irregular menstruation and dysmenorrhea. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 5-15 parts of ginseng, 10-20 parts of astragalus membranaceus, 10-15 parts of semen cuscutae, 10-15 parts of rhizoma atractylodis macrocephalae, 10-15 parts of angelica sinensis, 10-15 parts of parasitic loranthus, 10-15 parts of eucommia ulmoides, 10-15 parts of teasel root, 10-20 parts of radix rehmanniae preparata, 10-15 parts of radix paeoniae alba, 5-10 parts of radix bupleuri, 10-15 parts of rhizoma cyperi, 10-15 parts of codonopsis pilosula, 10-20 parts of Chinese yam, 10-15 parts of dogwood, 10-15 parts of cortex moutan, 10-15 parts of pericarpium citri reticulatae, 10-15 parts of poria cocos, 10-15 parts of fried semen coicis and 10-15 parts of scorched medicated leaven. According to the traditional Chinese medicine composition, the holism concept of traditional Chinese medicine is exerted, the effects of reinforcing qi, nourishing blood, relieving depression, regulating menstruation and preventing miscarriage are achieved by nourishing the kidney, the liver and the spleen, and conditioning of the internal organs of the body is achieved.

The application discloses a traditional Chinese medicine composition and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition is mainly composed of the following medicinal materials in parts by weight: 3-35 parts of Semen Euryae, 3-35 parts of kidney-tonifying medicinal materials, 5-35 parts of Salvia miltiorrhiza, 3-35 parts of blood-activating and stasis-removing medicinal materials, 5-60 parts of Astragalus membranaceus, 1-20 parts of Pericarpium Citri Reticulatae and 6-35 parts of Dioscorea opposita. The kidney-tonifying medicinal materials are Dipsacus asper or Morinda officinalis, and the blood-activating and stasis-removing medicinal materials are Spatholobus suberectus or Panax notoginseng. The traditional Chinese medicine composition has the functions of tonifying kidney and activating blood, is aimed at recurrent pregnancy loss (RPL) of the type of kidney deficiency and blood stasis, has the bidirectional regulating function of anticoagulation and hemostasis, and can be used for preventing RPL combined with prethrombotic state (PTS) and metrorrhagia during pregnancy before pregnancy, and treating RPL combined with PTS and metrorrhagia during pregnancy after pregnancy, and has a great application prospect.

The invention belongs to the technical field of health-care wine, and particularly relates to waist-strengthening and kidney-tonifying wine which is prepared from morinda officinalis, cistanche deserticola, eucommia ulmoides, ginseng, cornu cervi pantotrichum slices, gecko, teasel, rhizoma drynariae, rock candy and 50-degree rice wine through related processing. The medicinal materials are ground and ultrasonically extracted, so that the dissolution of functional main components in the traditional Chinese medicine powder can be promoted, the soaking time of traditional Chinese medicines can be shortened, the content of effective components in the wine can be increased, and the wine not only can keep the flavor of the wine and has higher palatability, but also has the effects of tonifying the kidney, strengthening the waist and knees and improving the immunity. And the health-care tea is suitable for long-term drinking of middle-aged and elderly people with symptoms of waist and knee pain, frequent urination at night, physical weakness and low immunity.

The invention belongs to the technical field of Chinese patent medicine detection, and particularly relates to a construction method of a Gusongbao tablet fingerprint as well as the fingerprint and application of the Gusongbao tablet fingerprint, the Gusongbao tablet is detected by adopting a high performance liquid chromatography and mass spectrometry combined technology, 39 common peaks can be identified and analyzed at the same time by systematically and reasonably controlling chromatographic conditions, and the sensitivity of the Gusongbao tablet is improved. 15 characteristic components are identified and are used for representing six medicinal materials including herba epimedii, radix dipsaci, radix paeoniae rubra, rhizoma chuanxiong, rhizoma anemarrhenae and rhizoma sparganii in the Guisongbao tablet. The established fingerprint spectrum covers the main effective components in the Gusongbao tablet, the detection precision of the chemical components in the Gusongbao tablet is greatly improved, the types and quantity of the contained chemical components are comprehensively reflected, the product quality is comprehensively controlled, and the quality consistency of each batch of products is ensured.

The traditional Chinese medicine formula is characterized by being prepared from the following raw materials in parts by weight: 35 to 42 parts of radix rehmanniae preparata, 15 to 22 parts of rhizoma dioscoreae, 15 to 20 parts of fructus lycii, 17 to 25 parts of rhizoma curcumae longae, 17 to 25 parts of radix dipsaci asperoidis, 20 to 26 parts of semen cuscutae, 22 to 31 parts of fructus psoraleae, 20 to 26 parts of herba epimedii, 25 to 32 parts of radix morindae officinalis and 12 to 17 parts of liquorice root. The preparation method comprises the following steps: step 1, cleaning and drying the medicinal materials, and processing and weighing the medicinal materials; step 2, putting the medicines into a vessel, and adding water for soaking; 3, boiling with big fire, decocting with small fire for 30-40 minutes, and filtering out liquid medicine; 4, adding clear water, boiling with big fire, continuously decocting with small fire for 20-30 minutes, and filtering out liquid medicine; and step five, mixing the liquid medicine in the step three and the liquid medicine in the step four, and taking the mixture for several times. The traditional Chinese medicine composition has the beneficial effects of fully cultivating and consolidating basis, ensuring kidney maintenance and improving the overall drug effect.

This invention proposes a traditional Chinese medicine compound for treating ankylosing spondylitis of the kidney-deficiency and damp-heat type accompanied by gastrointestinal dysfunction, along with its preparation method, belonging to the field of traditional Chinese medicine technology. The compound consists of Smilax glabra, Bletilla striata, Paris polyphylla, Geranium wilfordii, Dioscorea hypoglauca, Patrinia scabiosaefolia, Dipsacus asper, Drynaria fortunei, Pyrola rotundifolia, Clematis chinensis, Pheretima aspergillum, Lycopodium clavatum, Corydalis yanhusuo, Paeonia lactiflora, Atractylodes macrocephala (fried), Coix lacryma-jobi (raw), Aucklandia lappa, and Glycyrrhiza uralensis. This invention combines these herbs to achieve a synergistic effect, collectively clearing heat and dampness, strengthening the spleen and kidneys, and unblocking the meridians. The overall formula addresses both strengthening the body's foundation and eliminating pathogenic factors, ensuring unobstructed meridian flow and relieving arthralgia. This compound has the functions of clearing heat and dampness, strengthening the spleen and kidneys, and unblocking the meridians. It offers a short treatment course, rapid efficacy, low recurrence rate after cure, few side effects, and is inexpensive and convenient to use for treating ankylosing spondylitis with gastrointestinal dysfunction.

The invention discloses an anticancer antipyretic traditional Chinese medicine preparation and a preparation method thereof. The anticancer antipyretic traditional Chinese medicine preparation is prepared from honeysuckle, sticktight, corydalis tuber, immature bitter orange, verbena, laggera pterodonta, rhizoma acori graminei, teasel root, Mitsubishi, curcuma zedoary, radices trichosanthis, cape jasmine and a specific proportion of blood stasis removing and antipyretic extract according to specific parts by weight. The method is characterized in that a multi-mode modern extraction technology is adopted, wherein the multi-mode modern extraction technology comprises ultrasonic-assisted ethanol extraction, steam distillation, enzymolysis-microwave combined extraction and supercritical CO2 extraction, and the extraction efficiency and purity of effective components in different medicinal materials are optimized in a targeted mode. The preparation has the effects of clearing away heat and toxic materials and promoting blood circulation to remove blood stasis aiming at the traditional Chinese medicine pathogenesis of stagnant heat of cancerous fever, and the bioavailability and the quality controllability are remarkably improved. Pharmacodynamic experiments show that the effects of the preparation in the aspects of reducing the body temperature of a model animal, inhibiting inflammatory factors and improving oxidative stress indexes are obviously superior to those of conventional western medicines, and a novel traditional Chinese medicine treatment choice which is safe, effective and good in stability is provided for cancerous fever.

The present application belongs to the technical field of Chinese medicine detection, and particularly relates to a construction method of a Gushenbao tablet fingerprint spectrum, the fingerprint spectrum and application thereof. The Gushenbao tablet is detected by using high performance liquid chromatography and mass spectrometry. By systematically and reasonably controlling chromatographic conditions, 39 common peaks can be simultaneously identified and analyzed, and 15 characteristic components can be identified, which are used to represent 6 medicinal materials, i.e. Herba Epimedii, Dipsacus asper, Radix Paeoniae Rubra, Rhizoma Chuanxiong, Rhizoma Anemarrhenae and Rhizoma Sparganii in the Gushenbao tablet. The established fingerprint spectrum covers main effective components in the Gushenbao tablet, greatly improves the detection precision of the chemical components in the Gushenbao tablet, and comprehensively reflects the types and quantities of the chemical components, which is beneficial to comprehensively control the product quality and help to ensure the quality consistency of each batch of products.

The invention provides a traditional Chinese medicine composition for treating chronic obstructive pulmonary disease. The traditional Chinese medicine composition is characterized by being prepared from the following components in parts by weight: 8-14 parts of radix astragali preparata, 3-7 parts of herba cistanche, 3-7 parts of fructus alpiniae oxyphyllae, 3-7 parts of rhizoma polygonati, 3-7 parts of radix dipsaci, 4-8 parts of rhizoma atractylodis macrocephalae fried with bran, 4-8 parts of radix salviae miltiorrhizae, 1-5 parts of semen brassicae, 2-6 parts of fructus perillae, 1-5 parts of semen lepidii, 1-5 parts of fructus trichosanthis, 1-5 parts of scorpio, 3-7 parts of earthworm, 1-5 parts of periostracum cicada, 1-5 parts of herba asari, 2-6 parts of radix saposhnikoviae and 2-6 parts of schizonepeta spike. The traditional Chinese medicine composition has the effects of regulating and tonifying lung and kidney, relieving cough and asthma, reducing phlegm and removing blood stasis, and is suitable for chronic obstructive pulmonary disease, chronic pulmonary heart disease, wheeze, chest distress and shortness of breath, aggravated motility, spontaneous perspiration and aversion to wind, cough, expectoration and other symptoms.

The invention discloses a traditional Chinese medicine ointment formula for treating kidney deficiency and damp-heat syndrome type chronic glomerulonephritis as well as a preparation method and application thereof. The ointment formula is prepared from astragalus membranaceus, codonopsis pilosula, bighead atractylodes rhizome, donkey-hide gelatin, radix aconiti lateralis preparata, semen cuscutae, eucommia ulmoides, the root of kudzu vine, dried ginger, medicated leaven, rhizoma polygonati, gynostemma pentaphylla, teasel root, lucid ganoderma, divaricate saposhnikovia root, ligusticum wallichii, the root of bidentate achyranthes, parasitic loranthus, deer-horn glue, angelica sinensis, pulp of dogwood fruit, caulis spatholobi, gastrodia elata and pyrrosia lingua. According to the pathogenesis characteristics of the chronic glomerulonephritis, according to clinical practice, treatment based on syndrome differentiation, emphasis on tongue vein change, emphasis on combination of four diagnoses, mastering of yin and yang, and taking flat as a period; five internal organs are harmonized, and spleen and kidney are used as the basis; warm and clear effects are combined, and dynamic and static effects are combined; clinical test results show that after the ointment provided by the invention is used for treatment, the improvement condition of a treatment group is obviously superior to that of a control group, and the total effective rates of the treatment group and the control group in the treatment effect of the traditional Chinese medicine syndromes are 93.3% and 46.7% respectively; therefore, the ointment has a remarkable curative effect in the aspect of relieving the traditional Chinese medicine syndromes of the patients with the kidney-deficiency damp-heat syndrome type chronic nephritis.

The invention discloses teasel glycosyl transferase and application thereof in production of alpha-hederaoside and teasel saponin B. The amino acid sequence of the teasel glycosyl transferase is shown as SEQ ID NO.1, and the nucleotide sequence of the coding gene of the teasel glycosyl transferase is shown as SEQ ID NO.2. The invention further discloses a preparation method of the teasel glycosyl transferase. After the glycosyl transferase is subjected to prokaryotic expression, a series of triterpenoid saponins can be catalyzed to be converted into triterpenoid saponin-3-(2-O)-glycoside products in a glycosylation manner, and the triterpenoid saponin-3-(2-O)-glycoside products comprise alpha-hederin and dipsacus asper saponin B. The discovery of the dipsacus asper triterpenoid saponin glycosyltransferase provides more optional biological elements for the biosynthesis of natural products, and has a good application prospect.

The invention belongs to the technical field of pharmaceutical compositions, and particularly provides a traditional Chinese medicine composition for treating chronic pelvic inflammation as well as a preparation method and a detection method thereof. The traditional Chinese medicine composition comprises 400-450 g of folium artemisiae argyi, 10-50 g of angelica sinensis, 300-400 g of sargentgloryvine stem, 10-50 g of wine-processed teasel root, 10-50 g of obscured homalomena rhizome, 10-50 g of vinegar-processed myrrh, 10-50 g of radix angelicae pubescentis, 10-50 g of radix paeoniae rubra, 10-50 g of dragon's blood, 10-50 g of cortex periplocae, 10-50 g of radix angelicae, 10-50 g of radix saposhnikoviae, 10-50 g of safflower carthamus, 10-50 g of mistletoe, 10-50 g of fried pepper, 10-50 g of vinegar-processed frankincense and 10- The traditional Chinese medicine has the characteristics of reinforcing qi, nourishing blood, nourishing liver and tonifying kidney; the traditional Chinese medicine composition has the effects of promoting qi and blood circulation, tonifying liver and kidney, strengthening vital qi, eliminating the pathogenic factors and recovering the pathogenic factors.

The invention belongs to the technical field of antibacterial products, and particularly relates to a traditional Chinese medicine probiotic anti-infection fermentation preparation and a preparation method and application thereof. The traditional Chinese medicine probiotic anti-infection fermentation preparation is sterilized fermentation liquor prepared from polygala tenuifolia, dipsacus asper, lactic acid bacteria and water. Before fermentation, the mass ratio of polygala tenuifolia, teasel and water is (10-20): (5-15): 1000, and the inoculation concentration of lactic acid bacteria is 108 / mL or above. A fermentation type antibacterial agent is prepared, components in polygala tenuifolia and dipsacus asper are subjected to metabolic recombination in the proliferation and metabolism process of lactic acid bacteria, the proportion of active components is adjusted, and finally the preparation with the antibacterial effect is formed.

The application relates to the technical field of traditional Chinese medicines, and particularly discloses application of a traditional Chinese medicine composition in preparation of a medicine for treating organ fibrosis. The traditional Chinese medicine composition is prepared from raw medicinal materials in the following proportions by weight: Semen Euryae 150-350, Fructus Lycii 100-200, Schisandra chinensis 30-60, Cnidium 20-50, Rosa laevigata 20-50, Semen Allii Tuberosi 20-50, Dipsacus asper 20-50, Cistanche 20-50, Rehmannia glutinosa 30-60, Cyathula 20-50, Herba Epimedii 40-100, Rubus chingii 20-50, Ginseng 15-35, Cornu Cervi 10-25, sea horse 15-35, Fructus Meliae Toosendan 15-35. The traditional Chinese medicine composition can be applied in preparation of the medicine for treating organ fibrosis, the obtained medicine has the effects of inhibiting lung fibrosis, reducing myocardial fibrosis and reducing kidney fibrosis, the effect is remarkable, the application is safe, and the price is low.

The invention discloses a preparation method and application of a glossy privet fruit-cistanche-danshen mixture, and belongs to the field of traditional Chinese medicine preparations. The glossy privet fruit, cistanche and danshen mixture comprises the following components: prepared rehmannia root, white paeony root, Chinese angelica, ligusticum wallichii, moutan bark, red-rooted salvia root, suberect spatholobus stem, cistanche, glossy privet fruit, longspur epimedium, teasel root, golden cypress, rhizoma anemarrhenae, spina date seed (fried), dogwood and barbary wolfberry fruit. The traditional Chinese medicine composition can be used for treating premature ovarian failure and polycystic ovarian syndrome, and the clinical application range is expanded.

The invention discloses a traditional Chinese medicine composition for tonifying kidney, nourishing blood and preventing miscarriage as well as a preparation method, a detection method and application thereof, and belongs to the technical field of traditional Chinese medicine, the traditional Chinese medicine composition comprises the following medicine raw materials in parts by weight: 450-550 parts of semen cuscutae, 400-430 parts of Chinese yam, 400-430 parts of angelica sinensis, 400-430 parts of parasitic loranthus, 400-430 parts of teasel root, 400-430 parts of radix paeoniae alba, 400-430 parts of fructus nelumbinis and 230-260 parts of radix aucklandiae. Experimental studies show that the composition can specifically regulate expression levels of thrombosis-related factors (TF, PAI-1 and antithrombin III AT-III) and inflammatory factors (IL-6) in trophoblast cells and vascular endothelial cells, so that placenta local abnormal thrombosis is inhibited, maternal-fetal interface immune inflammation reaction is improved, and recurrent abortion is effectively prevented and treated.

The invention discloses medicinal liquor for preventing and treating liver and kidney deficiency type osteoarticular degenerative change and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine compositions. The medicinal liquor for preventing and treating liver and kidney deficiency type bone joint degenerative change is prepared from the following raw materials in parts by weight: 12 to 18 parts of herba epimedii extract, 12 to 18 parts of fructus lycii, 10 to 15 parts of fructus psoraleae, 10 to 15 parts of semen cuscutae, 10 to 15 parts of herba cynomorii, 10 to 15 parts of radix morindae officinalis, 8 to 12 parts of fructus cnidii, 8 to 12 parts of herba cistanche, 8 to 12 parts of radix astragali seu hedysari, 8 to 12 parts of caulis spatholobi, 6 to 12 parts of radix angelicae sinensis, 6 to 12 parts of rhizoma drynariae, 6 to 12 parts of radix dipsaci, 6 to 10 parts of semen astragali complanati, 6 to 10 parts of cortex eucommiae, 6 to 10 parts of fructus jujubae and 800 to 1200 parts of pure The medicinal liquor can significantly improve clinical symptoms, pain degree and life quality of patients with liver and kidney deficiency type knee osteoarthritis, is good in safety and free of obvious serious adverse reactions, and has a good clinical application prospect.

The application discloses a traditional Chinese medicine composition for treating, relieving or preventing rheumatoid arthritis, and raw materials of the traditional Chinese medicine composition include smilax glabra, angelica pubescens, dipsacus asper, rabdosia lophanthoides, corydalis tuber, saposhnicovia divaricata, potentilla discolor, eupatorium fortunei, myrrha and radix clematidis. The traditional "frying" method is integrated into modern double gel preparation, a variety of extraction methods, oil and water-soluble matrix, and medicine and adjuvant are combined in one way, so that an external preparation is prepared, which has the advantages of water-soluble and fat-soluble components, less component loss, high absorption, significant drug effect, and oil and water gel.

The oral traditional Chinese medicine for treating fracture comprises main components and auxiliary components, and the auxiliary components comprise 15-25 g of semen brassicae and 15-25 g of jasmine. The auxiliary components further comprise 25-30 g of radix violae chinensis and 25-30 g of cortex albiziae. The main components comprise safflower, peach fruit, pseudo-ginseng, teasel root, radix bupleuri, ligusticum wallichii, angelica sinensis, fried rhizoma cyperi, costus root, radix rehmanniae, radix paeoniae rubra, ground beeltle, hematoxylon, curcuma zedoary, fried rhubarb, herba lycopi, polygonum cuspidatum, dragon's blood, ophisaurus harti, hippocampus, syngnathus, fried frankincense, fried myrrh and the like. The oral traditional Chinese medicine for treating fracture has good effects of promoting qi circulation to relieve pain, promoting blood circulation to remove blood stasis, tonifying liver and kidney and promoting reunion of fractured bones, has no toxic or side effect, and achieves better functions of promoting qi circulation to relieve pain, promoting blood circulation to remove blood stasis, warming yang and promoting urination, tonifying liver and kidney and promoting reunion of fractured bones through innovative combination of the prescription medicines.

The invention belongs to the technical field of biological medicines, and particularly relates to application of dipsacus asper saponin B in preparation of a medicine for treating or preventing inflammatory bowel diseases. The technical problem to be solved by the invention is to provide a new choice for treatment of colitis. The technical scheme of the invention is application of dipsacus asper saponin B in preparation of drugs for treating or preventing inflammatory bowel diseases. The invention defines that the dipsacus asper saponin B has a treatment effect on colitis, systematically explains the mechanism of the dipsacus asper saponin B, and provides a brand new scientific basis and data support for development of the dipsacus asper saponin B as a medicine for treating inflammatory enteritis.

This invention belongs to the field of traditional Chinese medicine. Specifically, it relates to a traditional Chinese medicine composition, preparation method, and application for treating ankylosing spondylitis. The raw materials include 10-20 parts of Achyranthes bidentata, 10-20 parts of Dipsacus asper, 5-15 parts of Astragalus complanatus, 5-15 parts of Curculigo orchioides, 10-15 parts of Spatholobus suberectus, 10-20 parts of Salvia miltiorrhiza, 5-10 parts of Liquidambar formosana, 5-10 parts of Clematis chinensis, 10-15 parts of Clematis armandii, 5-15 parts of Pinus massoniana, and 5-15 parts of Scrophularia ningpoensis. This formula is meticulously formulated, addressing both the root cause and the symptoms: it combines tonification and purgation, nourishing the liver and kidneys to treat the root cause, while also dispelling wind and cold, and promoting blood circulation to treat the symptoms. This formula can be used to treat ankylosing spondylitis with symptoms of liver and kidney deficiency, qi and blood stagnation, and cold-dampness obstruction, such as pain, stiffness, and limited mobility in the spine or sacroiliac joints, with significant stiffness upon waking and relief after activity, or accompanied by peripheral joint pain, aversion to cold, cold limbs, dark tongue or ecchymosis, and a deep, hesitant or wiry pulse.

The application discloses a composition for treating traumatic injury and a preparation method thereof, and a traumatic oil yarn. The composition for treating traumatic injury comprises black soybean oil and a compound extract mixed with the black soybean oil, wherein the compound extract comprises oil extracts of the following traditional Chinese medicinal materials: pinellia ternate, prepared wujiabaicang, prepared asters, prepared aconite, ginseng, saposhnicovia divaricata, borneol, safflower, dipsacus asper, paris polyphylla, radix paeoniae, salix caprea leaf and radix scrophulariae. The composition for treating traumatic injury is prepared by compounding the oil extracts of the various traditional Chinese medicinal materials with the black soybean oil, so that the black soybean oil and the extracts of the various traditional Chinese medicinal materials play a mutual synergistic effect, the composition for treating traumatic injury is effectively enhanced in the effects of promoting blood circulation to remove blood stasis, relieving swelling and relieving pain on the tibia sprain, and the composition for treating traumatic injury also has the effect of promoting the healing of broken skin.

The invention discloses a medicinal moxa composition for preventing and treating seborrheic dermatitis and myasthenia. The medicinal moxa composition comprises notopterygium root, eucommia ulmoides, teasel root, semen plantaginis and moxa. Based on the theory of'the bladder dominates the exterior and the liver and kidney dominates the tendons', the medicinal moxa composition disclosed by the invention starts from the bladder meridian, and simultaneously improves the symptoms of seborrheic dermatitis and myasthenia through the effects of dispelling wind and eliminating dampness, nourishing the liver and the kidney, strengthening the muscles and bones, clearing heat and promoting diuresis and the like. The eucommia ulmoides can tonify liver and kidney and strengthen muscles and bones; radix dipsaci tonifies liver and kidney and strengthens muscles Semen plantaginis clears heat and promotes diuresis; the moxa has the effects of warming channels and expelling cold, promoting blood circulation to remove meridian obstruction, clearing damp and relieving itching, and killing parasites and stopping bleeding, and the five medicines are compatible to form a balanced system for dispelling wind and eliminating dampness, tonifying liver and kidney, strengthening muscles and bones, and clearing heat and promoting diuresis. The medicinal folium artemisiae argyi composition disclosed by the invention can be used for remarkably improving the skin symptoms of patients with seborrheic dermatitis and enhancing the muscle strength of the patients with myasthenia at the same time.