16 results about "Bone augmentation" patented technology

The invention discloses a magnetoelectric stent for realizing bone repair under external field driving and a preparation method and application thereof.The stent comprises a stent body based on a triple-period minimal curved surface structure and a magnetoelectric nano-particle coating, and the stent body comprises a convoluted and / or through hole structure; and the magnetoelectric nanoparticle coating is loaded on the inner surface of at least part of the pore structure. The magnetoelectric stent is suitable for providing better mechanical support for the early stage of bone repair of large-area bone defects, meanwhile, under the synergistic effect of magnetoelectric stimulation, osteogenesis and angiogenesis coupling can be promoted, and bone defect repair under the complex conditions of oral clinical alveolar bone vertical bone increment and systemic diseases such as inflammation and the like is achieved.

The present invention provides muscle-derived progenitor cells that show long-term survival following transplantation into body tissues and which can augment non-soft tissue following introduction (e.g. via injection, transplantation, or implantation) into a site of non-soft tissue (e.g. bone) when combined with a biocompatible matrix, preferably SIS. The invention further provides methods of using compositions comprising muscle-derived progenitor cells with a biocompatible matrix for the augmentation and bulking of mammalian, including human, bone tissues in the treatment of various functional conditions, including osteoporosis, Paget's Disease, osteogenesis imperfecta, bone fracture, osteomalacia, decrease in bone trabecular strength, decrease in bone cortical strength and decrease in bone density with old age.

The utility model discloses an oral implant which comprises a bone surface supporting structure, the appearance of the bone surface supporting structure is attached to an upper jaw alveolar bone surface or a lower jaw alveolar bone surface, and a net-shaped through hole is formed in the bone surface supporting structure and corresponds to the alveolar bone surface; a plurality of base tables protruding out of the surface are arranged on the surface of one side of the bone surface supporting structure, and the base tables are used for fixedly connecting the oral implant with a prosthesis; one end, connected to the bone surface supporting structure, of the abutment is provided with an intraosseous implant implanted into the jaw bone. According to the utility model, the traditional subperiosteal implant is improved, the subperiosteal implant is designed in the area with insufficient bone mass of the jaw bone, and the novel stent-shaped implant is formed by combining the subperiosteal implant with the intraosseous implant in the area with sufficient bone mass of the jaw bone, so that independent bone increment operation is not needed, and the implant can be implanted only by one operation; and the clinical problem that a patient with serious atrophy of the alveolar ridge is difficult to implant and repair is effectively solved.

The utility model discloses a 3D (three-dimensional) printing implant for oral implantation in the technical field of medical equipment, which comprises an implant structure, the implant structure comprises an implant body, the implant body is of a gradient pore net structure, a bioactive layer is arranged on the outer side of the implant body, and the bioactive layer is made of a transparent material. A bone meal attaching and guiding structure is arranged on the inner wall of a mesh hole of the implant body, a surface fixing structure is arranged on the surface of the implant body, and a bottom fixing structure is arranged at the bottom of the implant body. According to the utility model, the implant body is arranged into the net-shaped structure, and the bone meal attachment and guide structure is matched, so that the bone meal can be guided to directionally grow along the net-shaped pores, the traditional osteogenesis waiting stage is skipped, the implant implantation and bone increment are synchronously completed, and the damage to soft tissues caused by repeated bone meal filling and pressing operation is avoided.

This invention discloses a biomimetic helical chiral porous bone repair and bone augmentation scaffold, comprising: a scaffold body composed of an array of multiple lattice units, each lattice unit being a biomimetic trabecular bone cell; the lattice units follow the natural helical arrangement of human bone trabeculae, forming a continuous and interconnected helical channel network within the scaffold body; the lattice units are distributed in a helical gradient along the radial direction of the scaffold body, and the outer wall of the scaffold body has a protruding structure integrally formed with the lattice units. This invention, through the deep coupling of the biomimetic helical chiral structure and cellular fluid dynamics, overcomes the limitations of traditional scaffolds with "static channels," forming a composite flow field of "high-speed guidance - low-speed vortex," effectively solving the problem of "nutrient islands," and significantly improving the survival rate and quality of osteoblasts in the central region.

The utility model discloses an oral cavity bone increment operation barrier membrane nail planting fixing auxiliary device which comprises a handle portion, a fixing portion and a fixing portion. The bent clamping end comprises two arc-shaped cranks, the rear ends of the two cranks are connected with the front ends of the two grab handles through connecting pivots respectively, and separation and reunion of the two cranks are controlled through tightness clamping of the two grab handles; the sides, close to each other, of the front ends of the two cranks are detachably provided with the chuck parts used for clamping the barrier film in the folded state. According to the scheme, the barrier film is clamped and positioned through the modularized chuck part, the barrier film can be clamped and stabilized in a non-contact mode through operation optimization of the scissor-type and lever-type mechanical handles, and an unshielded nailing operation space can be provided; the problems that in a traditional oral cavity bone increment surgery, a membrane nail is difficult to fix and position, tired to operate and poor in adaptation are systematically solved.

A method for dispensing a bone reinforcement composition into an intervertebral spacer and at least one adjacent vertebra can help retain the implant in situ. A cannula guide is inserted into a first vertebra guided by a live imaging system. A curved directional composition delivery cannula is inserted through a tubular body of the guide; then positioning the delivery cannula along a desired path, positioning an end using a curved end as a steering mechanism. The delivery cannula passes through a first vertebra, into the intervertebral spacer, and optionally into a second vertebra. A volume of reinforcement composition is dispensed using cyclical steps incrementally withdrawing the delivery cannula and dispensing of the reinforcement composition until the desired path is filled with reinforcement composition stabilizing the respective vertebrae and / or interbody devices relative to each other. In an alternate arrangement, the cannula is inserted through a guide integrated into the intervertebral spacer.

A method for dispensing a bone reinforcement composition into an intervertebral spacer and at least one adjacent vertebra can help retain the implant in situ. A cannula guide is inserted into a first vertebra guided by a live imaging system. A curved directional composition delivery cannula is inserted through a tubular body of the guide; then positioning the delivery cannula along a desired path, positioning an end using a curved end as a steering mechanism. The delivery cannula passes through a first vertebra, into the intervertebral spacer, and optionally into a second vertebra. A volume of reinforcement composition is dispensed using cyclical steps of incrementally withdrawing the delivery cannula and dispensing of the reinforcement composition until the path is filled with reinforcement composition stabilizing the respective vertebrae and / or interbody devices relative to each other. In an alternate arrangement, the cannula is inserted through a guide integrated into the spacer.

The application provides a polytetrafluoroethylene barrier film and its application and preparation method, and belongs to the technical field of biomedical materials. The polytetrafluoroethylene barrier film comprises a film body and a bioactive layer on the surface of the film body; wherein the material of the film body comprises polytetrafluoroethylene, and the outer surface of the film body has a polar group; the material of the bioactive layer comprises a hydrophilic bioactive molecule. In the polytetrafluoroethylene barrier film provided by the application, the polar group on the outer surface of the polytetrafluoroethylene film body interacts with and effectively combines with the hydrophilic bioactive molecule, the combination stability between the film body and the bioactive layer is improved, the adhesion and growth of osteoblasts can be realized, and then the new bone mass during the bone augmentation surgery using the polytetrafluoroethylene barrier film is improved. In addition, the hydrophilic bioactive molecule can also endow the polytetrafluoroethylene barrier film with multifunctionality due to its characteristics.

The application is a kind of periodontitis treatment before and after bone increment quantitative evaluation method based on curved surface tomography, which firstly extracts the tooth feature point pair of the evaluated part in the oral curved surface tomography obtained twice before and after treatment, automatically extracts the feature point of the edge point, matches the feature point of the edge point in the two images; a registration model is constructed to transform the post-treatment oral curved surface tomography; according to the position of the feature point pair, the post-treatment oral curved surface tomography after registration is locally sliced to obtain the registered slice, and the image gray of the registered slice is segmented to obtain a plurality of consistent connected regions, the alveolar bone change target position is automatically selected, and the alveolar bone increment area is calculated by using the number of region pixels and the real resolution of the curved surface tomography. The application can accurately transform the post-treatment picture to the locally aligned position with the pre-treatment picture, automatically extract the change area, and then obtain the accurate alveolar bone increment area.

The utility model provides a titanium mesh for oral implantation, which not only can be conveniently taken out in sections, but also can reduce the risks of displacement and breakage during placement, and relates to the technical field of oral implantation. The oral implant titanium mesh comprises a bent arch-shaped titanium mesh body, the titanium mesh body comprises a titanium mesh edge and a pore structure arranged in the titanium mesh edge, a weak structure easy to break is arranged on the side face of one side of the titanium mesh body, and the weak structure easy to break comprises a groove body extending from one end of the titanium mesh body to the other end of the titanium mesh body. At least one supporting rod group is arranged in the groove body; the supporting rod set is composed of two supporting rods which incline towards the two sides of the width direction of the groove body respectively and intersect in an X mode, and the two ends of each supporting rod are connected with the inner walls of the two sides of the groove body respectively. A fracture guide groove is formed in the intersection position of the two supporting rods of the supporting rod set. According to the utility model, the flap turning area when the titanium mesh is taken out in the later period can be reduced, and the treatment effect of the bone increment surgery can be better ensured.

A stent is an expansion system formed by compounding various materials to expand a bone increment space, comprises a bag body, is of a porous structure, is made of materials such as silk fibroin, gelatin, chitosan, silk, PET, PP, PE, PGA, PLL, PLA and PLGA, and expands after absorbing liquid to provide the bone increment space. The stent is suitable for minimally invasive surgery. When the stent is used, large-area soft tissue incision in an operation area is avoided, the stent can be implanted in a minimally invasive mode in advance in a remote incision and tunnel separation mode, and the stent needs to be placed between a bone wall and the soft tissue. After being delivered to a target increment part, the stent expands due to imbibition, so that the volume is increased, the stent is integrated with tissues, and bone increment is finally realized by inducing osteogenic differentiation.

The present invention provides methods of distributing agents into bone and the maintenance of those agents within bone. These methods include mechanical, rheological, pharmacological, and other methods. By maintaining injectates within a targeted location in bone and increasing their distribution in bone, the methods are useful for purposes including but not limited to increasing local concentration, improving therapeutic effectiveness, increasing duration of action, and decreasing systemic toxicity. These same methods can displace the contents of bone toward a harvesting instrument for purposes of collection with similar and complimentary methods. The methods are useful for controlling the rate of egress of intraosseous distribution of agents or cells for a variety of purposes, including but not limited to: augmenting stem cell recovery in bone marrow aspiration, chemotherapy, medication delivery, treatment of infection, bone augmentation, and the like.

This invention discloses a CAD / CAM lingual alveolar bone augmentation combined with cortical bone incision guide, comprising a maxillary guide for assisting maxillary orthodontics and a mandibular guide for assisting mandibular orthodontics. The maxillary guide includes an upper guide positioning part and an upper guide body. The upper guide positioning part is integrally set on the anterior side of the upper guide body and is fitted and fastened to the maxillary teeth, so that the upper guide body is fitted against the palatal part of the maxilla. The mandibular guide includes a lower guide body, a lower guide positioning part, and a guide lingual guard. The lower guide positioning part is integrally set on the anterior side of the lower guide body and the guide lingual guard is integrally set on the posterior side. The manufacturing method includes: step one, obtaining a digital three-dimensional model; step two, digital guide design. This invention ensures the accuracy of the bone graft range and the adequacy of the bone graft volume during surgery, fills the gap in lingual surgical techniques, and promotes the widespread application and standardization of lingual bone augmentation combined with cortical bone incision.

A method for dispensing a bone reinforcement composition into an intervertebral spacer and at least one adjacent vertebra can help retain the implant in situ. A cannula guide is inserted into a first vertebra guided by a live imaging system. A curved directional composition delivery cannula is inserted through a tubular body of the guide; then positioning the delivery cannula along a desired path, positioning an end using a curved end as a steering mechanism. The delivery cannula passes through a first vertebra, into the intervertebral spacer, and optionally into a second vertebra. A volume of reinforcement composition is dispensed using cyclical steps of incrementally withdrawing the delivery cannula and dispensing of the reinforcement composition until the path is filled with reinforcement composition stabilizing the respective vertebrae and / or interbody devices relative to each other. In an alternate arrangement, the cannula is inserted through a guide integrated into the spacer.

The present invention relates to methods for preparing a crease patterned fibre article, a crease patterned fibre article obtainable by said method as well as the use of a crease patterned fibre article as a packaging, design article, fabrics, bio-tissue implant, organ substitute, organ regeneration (patch), organ model, tissue substitute, tissue model, tissue scaffolds, cell growth support, cell maturing support or bone reinforcement.