71 results about "Bone Trabeculae" patented technology

The invention discloses a bone trabecula hip joint system. The system comprises a series of bone trabecula assembled femoral components, caput femoris, bone trabecula oversleeves, bone trabecula assembled acetabular cups and bone trabecula acetabulum cushion blocks. The surface structures of the bone trabecula assembled femoral components, the caput femoris, the bone trabecula oversleeves, the bone trabecula assembled acetabular cups and the bone trabecula acetabulum cushion blocks are all metal bone trabecula structures and manufactured by means of the metal 3D printing technology, the structural form of holes and porosity can be accurately controlled, a plurality of specifications are available, and assembly can be conducted freely. The system has the advantages that fastness and effectiveness are realized, postoperation osseointegration is facilitated, service life is prolonged, postoperation revision rate is reduced, serious femur and acetabulum deformation is effectively solved, complicated joint primary replacement surgery and revision surgery under the condition of various forms of bone defects can be conducted, and the requirements of various patients for prosthesis customization are met.

The invention discloses a metal bone trabecula. The metal bone trabecula comprises at least three crossed metal bone trabecula supports, a micro-topological grid structure is embedded into the metal bone trabecula, and at least three intersection points are formed between the micro-topological grid structure and the metal bone trabecula supports. The bone trabecula is formed by regularly or irregularly arranging hollowed-out unit structure bodies in a three-dimensional space, the weight reducing effect is obvious, meanwhile, the requirement of rigidity and strength of different areas of partscan be met at the same time, stress shielding is avoided, and good matching of high strength and high weight reduction ratio can be achieved; in addition, after growing into the bone trabecula structure comprising a micro-topological grid, human body sclerotin can be fused with bone, bone ingrow can be induced to the largest extent, and accordingly long-term biological fixation of a prosthesis canbe achieved. Meanwhile, the invention further discloses a bone implant comprising the metal bone trabecula. The bone implant can achieve personalized customization through 3D printing, the process issimplified, and the economic cost is greatly reduced.

A device for forming a cavity in a centrum comprises a cutting part and a control device, wherein the cutting part is used for cutting the centrum and the control device is used for controlling the cutting part to cut the centrum. The control device comprises a bearing part used for bearing the cutting part, and the end, adjacent to the cutting part, of the bearing part is provided with a bendable portion. The bearing part comprises a direction limiting part used for controlling the bending direction of the bearing part and a limiting part used for controlling the bending angle of the bearing part. The bearing part can further comprise a protective part. The control device further comprises a manipulation assembly used for controlling the bearing part to bend. The device can effectively avoid dangers caused by bilateral puncture in the prior art, the shape of the cavity is controllable, meanwhile, damage to bone tissue is reduced, and bone cement can permeate between bone trabeculae more effectively.

The invention discloses a biological-type knee joint partition bone trabecula tibial plateau. The biological-type knee joint partition bone trabecula tibial plateau comprises a reniform plateau bearing part, a handle is arranged in the middle of the lower surface of the reniform plateau bearing part, parts, except the connecting handle, of the lower surface of the reniform plateau bearing part areprovided with bone trabeculae, and the reniform plateau bearing part is divided into an inner side area, a middle area and an outer side area; the hole diameter and porosity of the bone trabeculae inthe inner side area are larger than those of the bone trabeculae in the outer side area and the middle area in sequence. The partition bone trabecula tibial plateau is integrally formed through 3D printing of titanium alloy, and the hole diameters and porosities of the bone trabeculae arranged in different areas of the lower surface of the tibial plateau are different. An experiment proves that through partition arrangement of the bone trabecula of the biological-type knee joint tibial plateau, under the actual circumstance of uneven stress of the tibia, uniform bone ingrowth is achieved, andthe long-time stability of the biological-type tibial plateau is improved. through 3D printing, the surface of the whole component is rough, friction between the plateau and the tibia is increased, and the initial stability of the plateau is improved.

The invention provides an ultrasonic apparatus for preventing osteolysis from appearing around a prosthesis after joint replacement. The ultrasonic apparatus is mainly composed of a processor, an ultrasonic generator, an output probe, a display screen, an operation rotary knob, a power supply and an ultrasonic apparatus shell, wherein the processor and the ultrasonic generator are located in the ultrasonic apparatus shell, the processor, the ultrasonic generator and the display screen are connected with the power supply in series, and the ultrasonic generator is connected with the output probe. The ultrasonic apparatus is reasonable in design and convenient to carry, the ultrasonic frequency, the strength, the duty ratio, the working hour span and the area of the output probe can all be adjusted and matched with data bases composed of different parameters combinations, different types of parameter setting can be arranged as required, probes in different sizes can be adopted as required, corresponding low-energy ultrasonic waves are transmitted to the area around the prosthesis, therefore, the osteolysis is prevented from appearing around the prosthesis, reconstruction of bone trabeculas around the prosthesis is promoted, the bone mineral density around the prosthesis is improved, the service life of the prosthesis is prolonged, the ultrasonic apparatus is suitable for different people, no use contraindication exists, no invasive intervention occurs to a user, and the ultrasonic apparatus is relatively safe.

The invention relates to the technical field of medical instruments, in particular to a medical tantalum metal bone trabecula material prepared through a chemical vapor deposition method and a preparation method of the medical tantalum metal bone trabecula material. The preparation method specifically comprises the following process that tantalum pentachloride gas and high-purity hydrogen react for 6-9 h under the vacuum environment of 900 DEG C-1,050 DEG C, a tantalum metal layer obtained through replacement is deposited on the surface of a matrix, and the matrix and the tantalum metal layerdeposited on the surface of the matrix are the tantalum metal bone trabecula material; and the speed that the tantalum pentachloride gas is introduced into the vacuum environment ranges from 10,000 ml/min to 13,000 ml/min, the speed that the high-purity hydrogen is introduced into the vacuum environment ranges from 530 ml/min to 570 ml/min, and the vacuum degree of the vacuum environment is largerthan or equal to 4 Pa and is smaller than or equal to 13.3 Pa. Under cooperation of various reaction conditions, the preparation efficiency of the medical tantalum metal bone trabecula material is improved, and the tantalum metal bone trabecula material prepared through the preparation method is high in porosity, good in biocompatibility and good in friction coefficient, is highly similar to cancellous bones of human bodies and is a more ideal bone implant material.

The invention discloses a detachable pedicle screw. A screw body and a screw tail adopt a split type structure, micro holes are evenly formed in the screw body and the front end of the screw tail, and the axes of the micro holes are perpendicular to that of the screw body. The pedicle screw adopts the split type structure, namely, a spinning structure, a clamping structure, an insertion structure and the like, the screw body and the screw tail are made of magnesium alloys having advantages of degradability, biocompatibility and the like, meanwhile, the micro holes perpendicular to the axis of the screw body are formed in the screw body and the front end of the screw tail, so that bone trabeculae can be distributed along the micro holes, synchronous reconstruction of the bone trabeculae is allowed during fracture healing, the continuity of the bone trabeculae in vertebrae is recovered, dual healing of fracture cortex and spongiosa is realized, the structure and mechanical conduction features are effectively recovered, the internal fixation complication incidence can be significantly reduced, the fracture treatment effect can be improved, peripheral soft tissue and blood circulation can be effectively protected, the internal fixator related complication occurrence risk is reduced, and pain and economic burden caused by secondary major surgery on patients are avoided.

The invention relates to the technical field of medical apparatus and instruments, and provides a thighbone far-end prosthesis capable of preserving epiphysis. The thighbone far-end prosthesis comprises a thighbone far-end prosthesis body and a myeloid needle sleeve, wherein the thighbone far-end prosthesis body and the myeloid needle sleeve are in taper fit. The thighbone far-end prosthesis bodyis provided with a lower end face; a lower end protrusion is arranged on the lower end face, and a third bone trabecula structure is arranged on the surface of the lower end protrusion; and the myeloid needle sleeve is provided with a solid inner wall, and a second bone trabecula structure is arranged on the surface of the solid inner wall. The beneficial effects lie in that the lower end protrusion is customized in size according to the medullary cavity of a patient and matched with the medullary cavity of the patient, rapid intraoperative positioning can be achieved, the postoperative prosthesis is prevented from deviating front and back, and the prosthesis is prevented from damaging the bone of the patient. The third bone trabecula structure is arranged on the surface of the lower end protrusion, so that the contact area between the prosthesis body and human bones is increased, the bone ingrowth places can be increased, and the prosthesis body is more stable and firmer and is not easy to dislocate.

The invention relates to application of a group of thio-matrine derivative and salts thereof to preparation of an anti-osteoporosis medicament. The structural general formula of the thio-matrine derivative is shown in the description, where X is a sulfur atom, and an R group is selected from a hydrogen atom, an alkyl group, halogen, nitryl and a cyano group. The group of compositions is proven by bioactivity tests to remarkably reduce the bone mass loss of an ovariectomized mouse, represented by increase of the number of bone trabeculae, the bone surface and bone volume ratio, the relative bone volume or bone volume fraction and the number of bone trabecula connections, and remarkably suppress differentiation of RAW264.7 cells and primary monocytes of the mouse to osteoclasts, and thus can be developed into an anti-osteoporosis medicament or used for preparing a reagent for researches on pathological mechanism of osteoporosis and evaluation of the curative effect of the anti-osteoporosis medicament.

A device for forming a cavity in a centrum comprises a cutting part and a control device, wherein the cutting part is used for cutting the centrum and the control device is used for controlling the cutting part to cut the centrum. The control device comprises a bearing part used for bearing the cutting part, and the end, adjacent to the cutting part, of the bearing part is provided with a bendable portion. The control device further comprises a manipulation assembly used for controlling the bearing part to bend, and the manipulation assembly is arranged to generate action force in the axial direction of the bearing part to control the bearing part to bend. The device can effectively avoid dangers caused by bilateral puncture in the prior art, the shape of the cavity is controllable, meanwhile, damage to bone tissue is reduced, and bone cement can permeate between bone trabeculae more effectively.

The invention discloses minocycline hydrochloride nano sustained-release gel as well as a preparation method and application thereof, and belongs to the technical field of medicines. The problem of low encapsulation efficiency of small-molecule hydrophilic medicines is solved by introducing a form of a novel complex formed by chelating minocycline hydrochloride, metal ions and a compound with a plurality of sulfate, sulfonate or phosphate functional groups. Prepared minocycline hydrochloride multiple emulsion nanoparticles are smooth, round, high in encapsulation efficiency and strong in drug loading capacity. A prepared minocycline hydrochloride multiple emulsion nanoparticle is dispersed in a temperature-sensitive gel matrix to construct a double-layer delivery system which has certain biological adhesion, is good in periodontal retention and is convenient for administration. According to the minocycline hydrochloride nano sustained-release gel as well as the preparation method and application thereof, while the positioning advantage of the gel is exerted, burst release of a medicine can be remarkably reduced, the medicine administration period can be prolonged, possibility is created for further periodontal pocket local medicine administration treatment of periodontitis, the nanoparticles can penetrate through alveolar bone trabecula and bottom connective tissue, distribution of the medicine at a focus position is enhanced, and the antibacterial effect of the medicine is remarkably improved.

The invention relates to the technical field of medical instruments, and provides a dental implant with an osteoinduction structure. The dental implant comprises a solid part, a bone trabecula part and a tantalum coating part; wherein an integrally-formed base platform part and a root part are arranged at the top of the solid part, the solid part is provided with a rough surface formed by spraying, irregular pore structures are formed on the rough surface, the bone trabecula part is arranged on the irregular pore structures, and the tantalum coating part is arranged on the bone trabecula partof the solid part through 3D printing; and three blade parts with a self-tapping function are arranged on the root part. The dental implant has the beneficial effects that the irregular pore structures are formed on the solid part, so that the contact area with normal sclerotin is extended; a porous bone trabecula structure is beneficial to new bone ingrowth, sufficient space is provided for vascular regeneration and new bone regeneration, and the later-period stability of the implant is guaranteed; and tantalum metal is sprayed to the implant, the osseointegration process is shortened due tothe good biocompatibility, and the clinical osseointegration rate is increased.

The invention discloses a personalized bone-imitating trabecularism metal gasket based on a 3D printing technology. The personalized bone-imitating trabecularism metal gasket based on the 3D printingtechnology comprises a metal bottom plate compatible with a human body, wherein an inner structural layer, a middle structural layer and an outer structural layer are sequentially arranged on the metal bottom plate through the 3D printing technology and are not limited to three antique trabecularism layers, and the porosity of the inner structural layer is smaller than that of the middle structural layer. Due to the fact that metal bottom plates with uniform specifications are manufactured in advance, fine adjustment is facilitated when the metal bottom plates need to be used; the requirementsof different patients can be met conveniently; the personalized bone-imitating trabecularism metal gasket based on the 3D printing technology can directly scan through a laser scanner to obtain fine-tuned graphs and sizes, measurement and drawing time is saved, and rapid modeling is facilitated; and models of the inner structural layer, the middle structural layer and the outer structural layer are preset in three-dimensional software, the thickness and the porosity can be adjusted, personalized construction can be quickly realized, and the requirements on operators are reduced.

The invention is applicable to the technical field of medicines, and provides prunus humilis procyanidins, a preparation method and application thereof, and a medicine; the preparation method of the prunus humilis procyanidins comprises the following steps: preparing and depitting prunus humilis to obtain depitted prunus humilis; carrying out ultrasonic extraction on the prunus humilis and an ethanol aqueous solution at the temperature of 30-50 DEG C to obtain an extracting solution; and carrying out suction filtration on the extracting solution, and then carrying out vacuum concentration andfreeze-drying treatment to obtain the prunus humilis procyanidine. The active ingredients in the prunus humilis bunge are extracted and prepared into the freeze-dried powder, so that the biological activity of the prunus humilis bunge can be maintained, the prunus humilis is convenient to store and transport, and the prunus humilis freeze-dried powder has important significance in development of the prunus humilis industry and meeting of increasing large health requirements of people. In addition, the prunus humilis procyanidine has the effects of preventing osteoporosis, maintaining a bone structure, protecting the integrity of a bone trabecula microstructure, improving estrogen disorder caused by menopause, regulating and controlling intestinal flora metabolites of organisms and the like.

The invention relates to a 3D printing individualized customized bionic micropore acetabulum mortise and tenon patch and a manufacturing method, the mortise and tenon patch is of a 3D printing solid structure, the upper edge and the lower edge of the inner side face are connected with one side edge of the upper surface and one side edge of the lower surface respectively to form a tenon structure embedded into the acetabulum bone defect position. The upper edge and the lower edge of the outer side surface are respectively connected with the other side edges of the upper surface and the lower surface to form an integral mortise and tenon patch structure in a surrounding manner; the lower surface is arc-shaped, and the radian of the lower surface is the same as that of an acetabular cup prosthesis; through the arrangement of the four forms of threaded holes, multi-angle fixation of the mortise and tenon patch can be guaranteed, the stability is guaranteed to the maximum extent, and sideslip or displacement is prevented. And through bone-like trabecular bionic micropores are formed in the mortise and tenon patch. The problems that in the acetabular bone defect reconstruction process in the prior art, the rotation center of a hip joint cannot be recovered easily, an implant and a bone defect form are not matched, bone ingrowth of the implant is poor, and initial and long-term stability is poor are solved.

The invention relates to the technical field of medical instruments, and provides an individualized pelvic prosthesis. The individualized pelvic prosthesis comprises a solid part made of titanium alloy, a large aperture bone trabecula part made of titanium alloy, a small aperture bone trabecula part made of titanium alloy, a pterygoid lamina made of titanium alloy, and self tapping bone nails madeof titanium alloy, wherein the large aperture bone trabecula part made of titanium alloy comprises a first large aperture bone trabecula and a second large aperture bone trabecula; the small aperturebone trabecula part made of titanium alloy comprises a first small aperture bone trabecula and a second small aperture bone trabecula; multiple self tapping bone nails made of titanium alloy are arranged; and the installation position of the self tapping bone nails made of titanium alloy on the solid part made of titanium alloy corresponds to the bone position connected with the self tapping bonenails made of titanium alloy. The individualized pelvic prosthesis in the invention has the benefits that: the prosthesis is connected with the bone by adoption of ten bone nails; the bone nails aredivided into four groups; and the initial stability of the prosthesis is enhanced due to distributed and grouped distribution of the bone nails.