Liquid chromatograph-mass spectrometer and control method thereof
By using a liquid chromatography-mass spectrometry (LC-MS) system with magnetic separation pretreatment and low-pressure liquid phase fluid delivery, the high cost and high failure rate of ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) equipment have been solved, enabling efficient detection of trace substances.
CN122282977APending Publication Date: 2026-06-26SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD
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Patent Information
- Application Number
- CN202511991189.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Priority Date
- 2024-12-25
- Filing Date
- 2025-12-25
- Publication Date
- 2026-06-26
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Figure CN122282977A_ABST
Abstract
This invention relates to the field of medical devices and discloses a liquid chromatography-mass spectrometry (LC-MS) device and a control method for the LC-MS device. The LC-MS device includes a sample storage device, a pretreatment device, a chromatographic element, a mass spectrometry detection device, and a controller. The chromatographic element includes a reagent preparation channel, a reagent transfer assembly, a liquid flow delivery assembly, and a chromatographic column. The liquid flow delivery assembly is used to drive the reagent in the reagent preparation channel through the chromatographic column to adsorb the reagent onto the column, and to drive the liquid flow through the chromatographic column to elute the adsorbed reagent to form the analyte. The pretreatment device uses magnetic separation to pretreatment the sample. The operating pressure of the liquid flow delivery assembly is less than or equal to 20 MPa. This invention reduces the cost of LC-MS devices.
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