Process for preparing O-carboxymethyl chitosan covalent binding chemical modification electrode

A carboxymethyl chitosan and chemical modification technology, which is applied in the field of electrochemical analysis and detection, can solve the problems that it is difficult to simultaneously eliminate or reduce the influence of AA and UA determination, the interference of DA content, etc., so that the electrode modification layer is firm and easy to use. The effect of long life and convenient production
CN1865967AInactive Publication Date: 2006-11-22YANGZHOU UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
YANGZHOU UNIV
Publication Date
2006-11-22
Estimated Expiration
Not applicable · inactive patent

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Abstract

The disclosed preparation method for an electrode chemical modified by O-carboxylmethychitose covalence bond comprises: dipping glass-carbon electrode into O-carboxylmethychitose-formic acid solution for modification, taking out to clean with formic acid and distilled water. This invention can improve detection sensitivity for DA, can eliminate effect of AA and UA, and has long lifetime.
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Description

technical field

[0001] The invention relates to a preparation method of an O-carboxymethyl chitosan covalently bonded chemically modified electrode, belonging to the technical field of electrochemical analysis and detection. Background technique

[0002] Dopamine (DA), also known as 3-hydroxytyramine, is a very important information-transmitting substance in the central nervous system of mammals and humans. Dysregulation of dopaminergic nerves in the brain is an important cause of schizophrenia and Parkinson's disease. Therefore, the research on its determination method is of great significance to explore its physiological mechanism and the diagnosis of related diseases. The determination of DA has always been a research hotspot in the fields of electroanalytical chemistry, biology and medicine. At present, the main methods for the determination of DA are fluorescence method, chemiluminescence method and capillary electrophoresis method. In its electrochemical determinatio...

Claims

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