34 results about "Fused silica capillary" patented technology

The subject invention concerns zirconia-based hybrid organic-inorganic sol-gel coating for optional use as a stationary phase in capillary microextraction (CME), gas chromatographic (GC), high performance liquid chromatography (HPLC), capillary electrophoresis (CE), capillary electrochromatography (CEC) and related analytical techniques. Sol-gel chemistry is employed to chemically bind a hydroxy-terminated silicone polymer (polydimethyldiphenylsiloxane, PDMDPS) to a sol-gel zirconia network. In one embodiment, a fused silica capillary is filled with a properly designed sol solution to allow for the sol-gel reactions to take place within the capillary. In the course of this process, a layer of the evolving hybrid organic-inorganic sol-gel polymer becomes chemically bonded to the silanol groups on the inner capillary walls. The unbonded part of the sol solution is expelled from the capillary under helium pressure, leaving behind a chemically bonded sol-gel zirconia —PDMDPS coating on the inner walls of the capillary. Polycyclic aromatic hydrocarbons, ketones, and aldehydes are efficiently extracted and preconcentrated from dilute aqueous samples followed by GC separation of the extracted analytes.

A separation column is provided with a photopolymer component which, when irradiated, causes controlled porosity polymerization. A particularly preferred embodiment is wherein the separation medium is retained by a photopolymer frit, which can be reliably and reproducibly generated with controlled porosity.

The invention discloses a mass spectrometric nano-spray electrode, a manufacturing method and the application thereof. The mass spectrometric nano-spray electrode is composed of a fused quartz capillary tube and a CNT (carbon nanotube) doped sol-gel composite material, wherein the CNT doped sol-gel composite material is coated on an outlet end of the capillary tube. The method for manufacturing the electrode comprises the following steps: firstly, carrying out pretreatment on the used fused quartz capillary tube and the CNT; then, preparing sol doped with the CNT; and finally, coating the outlet end of the fused quartz capillary tube with the sol, and carrying out solvent volatilizing and aging. The mass spectrometric nano-spray electrode disclosed by the invention has the advantages of good stability, high sensitivity, long service life, high reusability, simpleness for manufacturing, low cost, and capability of continuously realizing nano-spray for 52 hours and continuously being used 170 hours, and the like and can be continuously used for 170 hours, and the mass spectrometric results have good reproducibility; and the mass spectrometric nano-spray electrode can be used in CE (capillary electrophoresis) or capillary LCMS (liquid chromatography-mass spectrometry) analysis technique, and also can be used in a nano-spray mass spectrographic analysis technique.

The invention discloses a manufacturing method of an inclusion standard sample synthesized by a fused silica capillary. The manufacturing method includes the following steps: a fused silica capillary with the length of 45-60mm is intercepted; one end of the fused silica capillary is sealed; moderate liquid is sucked in the capillary through the other end of the fused silica capillary by using the siphon principle; high-speed centrifugal processing is performed on the fused silica capillary filled with the liquid by using a high-speed centrifugal machine so as to enable the liquid to sink at the bottom of the sealed end of the capillary; refrigeration is performed, and the liquid has phase transition to be condensed into a solid state; air in the capillary is exhausted by controlling a vacuum system; and pipe sealing is performed on the open end of the fused silica capillary under the vacuum state. The manufacturing method is simple to operate, small in equipment investment, high in production efficiency and finished product rate and regular in products.

A double-clad optical fiber fabrication method including the steps of: preparing a crystal fiber, inserting the crystal fiber into a silica capillary, attaching a sapphire tube to the periphery of the silica capillary, and applying a laser beam to the sapphire tube to increase the temperature of the sapphire tube and to further fuse the silica capillary with thermal radiation to have the fused silica capillary be wrapped about the crystal fiber, thereby forming the desired double-clad optical fiber.

A separation column is provided with a photopolymer component which, when irradiated, causes controlled porosity polymerization. A particularly preferred embodiment is wherein the separation medium is retained by a photopolymer frit, which can be reliably and reproducibly generated with controlled porosity.

A tip portion of a probe has a triple tube structure in which a fused silica capillary on the innermost side, a capillary made of FEP outside the fused silica capillary, and a stainless pipe on the outermost side are disposed coaxially. An eluate from a liquid chromatograph flows through the innermost flow passage, a matrix solution flows through the flow passage between the fused silica capillary and the FEP capillary, and a rinsing solution or air flows through the flow passage between the FEP capillary and the pipe.

Germania-based sol-gel organic-inorganic hybrid coatings were prepared for on-line coupling of capillary microextraction with high-performance liquid chromatography. A germania-based sol-gel precursor, tetra-n-butoxygermane and a hydroxy-terminated triblock copolymer, poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide), were chemically anchored to the inner walls of a fused silica capillary (0.25 mm I.D.). Scanning electron microscopy images of the sol-gel germania triblock polymer coating were obtained to estimate the coating thickness. The analyte distribution constants between a sol-gel germania organic-inorganic hybrid coating and the samples (Kcs) were determined. For a variety of analytes from different chemical classes, including polycyclic aromatic hydrocarbons (PAHs), ketones, alcohols, phenols, and amines, the Kcs values ranged from 1.8×101 to 2.0×104. The sol-gel germania triblock polymer coatings survived exposure to high temperature solvent conditions (200° C.) with little change in extraction capabilities. Reproducibility of the method for preparation of the sol-gel germania triblock polymer coatings was also evaluated, and the capillary-to-capillary RSD values ranged from 5.3% to 6.5%. The use of higher flow rates in extraction was found to significantly reduce the time required (from 30-40 minutes to 10-15 minutes) to reach equilibrium between the sol-gel germania triblock polymer coating and the analytes in the sample solution.

The invention discloses a nano-filler capillary chromatographic micro-column preparation device and a preparation method thereof, which relate to the preparation of a nano-filler capillary chromatographic micro-column. The nano-filler capillary chromatography microcolumn preparation device is provided with a centrifuge and a centrifugal filling device, and the centrifugal filling device is provided with a detachable PEEK joint, a PEEK interface, a PTFE sleeve, a capillary and a centrifuge tube. Take nanoparticles and disperse them in acetone, the concentration is controlled at 1-50 μg / μL, and the homogenate solution is mixed and oscillated to obtain a homogenate solution; a section of elastic quartz capillary is cut off, and a single through-hole silicon ball with a particle size slightly larger than the inner diameter of the capillary is pressed into the capillary One end is used as the outlet plunger; fix the capillary with the outlet plunger in the centrifugal filling device, inject the homogenate into the liquid storage tank, weigh and centrifuge, and fill the stationary phase; after the centrifugation is completed, remove the filled capillary, A through-hole silica gel particle is filled at the inlet end of the capillary as an inlet plunger to obtain a nano-filled capillary chromatographic microcolumn.

The invention belongs to the related technical field of semiconductor surface cleaning, and discloses a device and method for removing nano-scale particles adsorbed on the surface of a silicon wafer. The device includes a vacuum component and a droplet emission and acceleration component connected to the vacuum component; droplet emission and acceleration The components include liquid storage, graphite electrode, PEEK capillary, fused silica capillary and grounded extraction electrode; the liquid storage is set above the vacuum component, which is used to contain the conductive solution; the graphite electrode is set on the liquid storage, and its two ends are respectively used for contact with The DC power supply is connected and in contact with the conductive liquid; one end of the PEEK capillary is connected with the liquid storage, the other end is connected with the fused silica capillary, and one end of the fused silica capillary extends into the vacuum component; the extraction electrode is arranged in the vacuum component, and It is located opposite the emission tip formed by the fused silica capillary. The invention improves the cleaning efficiency, reduces the cost, and realizes no liquid residue after removal.

The invention relates to a method for determining content of gamma-aminobutyric acid through a micellar electrokinetic capillary chromatography method, and belongs to the technical field of chromatographic analysis. The method comprises the following steps of selection and pretreatment of a fused silica capillary column, electrophoretic analysis conditions, gamma-aminobutyric acid standard curve drawing, sample derivatization and quantitative analysis of gamma-aminobutyric acid. Compared with the prior art, the method has the following advantages that micellar electrokinetic capillary chromatography (MECC) is adopted, sodium dodecyl sulfonate (SDS) and beta-cyclodextrin serve as micelle, an organic modified isopropanol reagent is added, gamma-aminobutyric acid is rapidly, easily and efficiently separated from other free amino acids, and gamma-aminobutyric can be detected within 30 min.

The invention discloses a method for simultaneously accumulating, enriching and separating multiple arsenic forms in a natural medicine on line based on micelle-solvent accumulation. A zwitterionic surfactant PAPS is used for carrying out effective and sensitive two-step accumulation capillary zone electrophoresis CZE on As (V), As (III), MMA and DMA through electric injection and micellar-to-solvent accumulation MSS in co-electroosmotic flow co-EOF. The HDMB coating fuses the quartz capillary to satisfy the condition of the same EOF direction between the anion and the capillary. The background solution is a borax buffer solution. The micelle and the target analyte are injected and stacked through a field enhanced sample under negative pressure; methanol is injected, wherein the scanned analyte is brought by the micelles to the MSS boundary. According to the invention, arsenic in a natural drug is detected by using a micelle-to-solvent accumulation method through coating capillary electrophoresis, rapid detection of arsenic form is realized, and the sensitivity of on-line enrichment of a capillary electrophoresis sample is improved.

It is an object of the present invention to provide a manufacturing method of a micro-gripper which takes an optical fiber Fabry-Perot interferometer as a clamping jaw and which has a self-sensing function, wherein that micro clamp manufactured by the manufacture method can solve the problem that the clamping jaws of the micro clamp in the prior art can not simultaneously realize the clamping component and the clamping force self-sensing. The method comprises the following steps of: fusing silica capillary tube with reflective optical fiber and input / output optical fiber respectively to form optical fiber Fabry-Perot interferometer; forming a clamping portion of the jaw on the reflective optical fiber; forming an oxide layer on the upper and lower surfaces of the silicon wafer; photoetching a groove pattern on an upper oxide layer of a silicon wafer and a pattern of a monolithic flexible mechanism on a lower oxide layer of the silicon wafer by a photoresist, and etching a part of the silicon wafer that is not covered by the photoresist on an upper surface and a part of the silicon wafer that is not covered by the photoresist on a lower surface to form a groove and a monolithic flexible mechanism; installing the optical fiber Fabry-Perot interferometer with groove and single flexible mechanism respectively, and connecting the input / output optical fiber, the F-P demodulator, an actuator, the F-P demodulator and the controller correspondingly.

The invention discloses a mass spectrometric nano-spray electrode, a manufacturing method and the application thereof. The mass spectrometric nano-spray electrode is composed of a fused quartz capillary tube and a CNT (carbon nanotube) doped sol-gel composite material, wherein the CNT doped sol-gel composite material is coated on an outlet end of the capillary tube. The method for manufacturing the electrode comprises the following steps: firstly, carrying out pretreatment on the used fused quartz capillary tube and the CNT; then, preparing sol doped with the CNT; and finally, coating the outlet end of the fused quartz capillary tube with the sol, and carrying out solvent volatilizing and aging. The mass spectrometric nano-spray electrode disclosed by the invention has the advantages of good stability, high sensitivity, long service life, high reusability, simpleness for manufacturing, low cost, and capability of continuously realizing nano-spray for 52 hours and continuously being used 170 hours, and the like and can be continuously used for 170 hours, and the mass spectrometric results have good reproducibility; and the mass spectrometric nano-spray electrode can be used in CE (capillary electrophoresis) or capillary LCMS (liquid chromatography-mass spectrometry) analysis technique, and also can be used in a nano-spray mass spectrographic analysis technique.

The invention provides a gas chromatography-mass spectrometry detection method for a methylaniline compound. The method comprises the following steps of: A) extraction of a sample, namely adding an acid into the sample to extract the methylaniline compound into an acid liquor phase, adding alkaline into acid liquor phase extract to regulate pH to be neutral, adding methylene chloride to reextract the methylaniline compound in the neutral extract into the methylene chloride, and performing volume fixing to obtain a sample detection solution; and B) detection of the sample, namely separating the obtained sample detection solution by using a DB-1MS fused silica capillary column, and performing gas chromatography-mass spectrometry detection. The quantitative detection of the methylaniline compound is realized; the method is high in accuracy, low in detection limit, high in extraction efficiency and easy to operate, and can be widely applied to the detection of the methylaniline compound in a crude oil sample, a gasoline sample, a diesel sample and the like; the interference of other compounds in an extraction process can be eliminated; and powerful support can be provided for the environmental performance evaluation and monitoring of the sample.