60results about How to "High sensitivity measurement" patented technology

An electrical condition monitoring method utilizes measurements of electrical resistivity of an age sensor (303) made of a conductive matrix or composite disposed in a polymeric structure such as an electrical cable (301). The conductive matrix comprises a base polymer and conductive filler. The method comprises a means for communicating the resistivity to a measuring instrument (317) as a means to correlate resistivity of the conductive matrix of the polymeric structure with resistivity of an accelerated-aged conductive composite.

An extensometer having a loop of a single-mode optical fiber. At least two points of the loop are attached to desired locations on a specimen. Light is transmitted through the loop and the transmitted optical power is measured by a photodetector. The deformation of the specimen causes the size and shape of the loop to change, which changes the transmitted optical power. The change in optical power is related to extension or compression using calibration curves. The sensor works on the principle of transmitted power modulation through the curved section.

There is disposed, on a substrate 41 holding a sample to be detected, a dielectric multilayer 42 which reflects excitation light e1 supplied from above the substrate 41 and transmits fluorescence f1 emitted from the sample, and the excitation light e1 is reflected at the dielectric multilayer 42 while the transmitted fluorescence f1 is detected by a light receiving unit 44, thereby providing a fluorescence measurement apparatus which can resolve a problem of reduction in detection sensitivity due to autofluorescence from the substrate or leakage of the excitation light from a light receiving filter, and which can detect the sample with high sensitivity.

The invention discloses an SPR (Surface Plasma Resonance) based reflective index sensor with high sensitivity and a wide measurement range. The SPR based reflective index sensor is characterized by comprising a laser source, an optical isolator, a polarization controller, a microfluidic channel, a side polishing and grinding mono-mode optical fiber, a chip coated with a gold film on a glass slide, a spectrometer and a microfluidic pump, wherein an SPR sensing area comprises the chip coated with the gold film on the glass slide, the microfluidic channel and the side polishing and grinding mono-mode optical fiber; the microfluidic channel is formed in a residual cladding of the side polishing and grinding mono-mode optical fiber by virtue of a photo-etching technology; the chip coated with the gold film on the glass slide is formed by sputtering the gold film on the surface of a silicon substrate by virtue of an ion sputtering technology. Due to a strong evanescent field in the microfluidic channel and the SPR effect, great excursion is generated by an SPR wavelength when the reflective index of the microfluidic channel slightly changes; a great effective reflective index difference is generated on an interface between the chip coated with the gold film on the glass slide and the microfluidic channel, and thus the measurement range is widened. The SPR based reflective index sensor is practical and is low in cost.

The invention relates to a marine biochemical substance monitoring sensor based on CMUT (Capacitive Micromachined Ultrasonic Transducer) as well as a manufacturing method and a measuring method of the marine biochemical substance monitoring sensor. The overall structure of the sensor comprises an upper thin plate, an upper cavity, a vibration membrane, a lower cavity, a base, a sensitive material layer and a lower porous electrode from top to bottom, wherein the upper cavity and the lower cavity are respectively formed in the upper side and the lower side of the vibration membrane; the sensitive material layer is arranged on the lower surface of the base; the lower porous electrode is arranged on the lower surface of the sensitive material layer and provided with a through hole running through the thickness of the sensitive material layer; the vibration membrane is taken as an upper electrode at the same time. The sensor provided by the invention can be used for preventing the quality factors of the vibration membrane from being influenced by fluid damping in a liquid environment, so that the biochemical substances measurement with high sensitivity can be realized.

The invention discloses a differential interference phase detecting method and device of a vector beam excitation surface plasma. A radially polarized beam and an azimuthally polarized beam are generated by a light source unit so as to realize high sensitivity and large dynamic range detection by using a sensing unit and a detecting unit. According to the invention, the surface plasma resonance is excited by using an axisymmetric vector beam; and high sensitivity and large dynamic range detection is realized by using differential interference phase detection.

A chemiluminescent enzyme immunoassay method whereby a target substance such as a protein is assayed. This chemiluminescent enzyme immunoassay method comprises: the step of capturing an immune complex containing an enzyme-labeled antibody, which is labeled with an enzyme acting a chemiluminescent substrate, and the target substance on a support having no solution layer; the step of overlaying a support membrane containing the chemiluminescent substrate on the immune complex having been captured above; and the step of measuring the luminescence dose caused by the reaction between the enzyme-labeled antibody and the chemiluminescent substrate to thereby quantify the target substance. Since a highly sensitive chemiluminescent enzyme immunoassay is conducted by using a non-liquid phase type reaction system in the chemiluminescent enzyme immunoassay method as described above, multiple items can be assayed by using only a small amount of a specimen and, furthermore, the target substance can be assayed at a high sensitivity thereby without resorting to any troublesome procedures such as pipetting a reagent.

A tandem Fourier transform ion cyclotron resonance mass spectrometer is provided. In the mass spectrometer, the ions selected by a FT-ICR mass analyzer, which can perform an ion selection process and a mass measurement process with a time interval between the processes, are transmitted through an ion guide to a collision cell, which is located a predetermined distance from the FT-ICR mass analyzer, to split into fragment ions. The fragment ions are transmitted to the FT-ICR mass analyzer that measures the mass of the fragment ions. The fragment ions are generated in the collision cell 60 established separately from the FT-ICR mass analyzer 40 according to the mass spectrometer. Accordingly, It can solve various problems (e.g., the radius reduction of cyclotron motion of colliding ions, or the removal of periphery gas after generating the fragment ions) occurred in a tandem mass spectrometer using a conventional tandem-in-time mass analysis method. Also, a high resolution and with sensitivity measurement can be achieved. Moreover, when a reagent gas instead of a collision gas in the collision cell is injected, the gas phase reaction of the selected ions and the reagent gas can be observed, and the mass of the ions generated in the gas phase reaction can be measured.

A surface defect measuring apparatus and method by microscopic scattering polarization imaging is provided. The apparatus mainly comprises a laser, a first converging lens, a rotary diffuser, a second converging lens, a diaphragm, a third converging lens, a pinhole, a fourth converging lens, a polarizer, a half-wave plate, a polarizing beam splitter, an X-Y translation stage, a sample, a microscope lens, a quarter-wave plate, a micro-polarizer array, a camera and a computer. The micro-polarizer array is adopted to realize real-time microscopic scattering polarization imaging of the surface defects; a polarization-degree image is calculated to improve the sensitivity for detecting the surface defects of the ultra-smooth element, and the effective detection of the surface defects of a high-reflective coating element is also realized, and the requirement for rapid detection of the surface defects of a meter-scale large-aperture ultra-smooth element can be met.

Disclosed is an electrode member which has spherical sections, each of which configures a part of a sphere, and a plurality of spherical electrode sections wherein the radiuses of the spherical sections are different from each other. The spherical electrode sections are disposed in a state wherein the center points of the respective spheres match each other and the spherical electrode sections are insulated from each other such that voltages can be independently applied thereto. Electron-passing openings for straightly taking out electrons, which are moving from the center point, to the outside of the electrode are formed at positions where the spherical electrode sections and a plurality of straight lines radially extending from the center point intersect each other.

A device for attaching and detaching a cryogenic probe to and from a nuclear magnetic resonance (NMR) spectrometer. The device permits the probe to be loaded in the spectrometer in a shortened time and achieves high measurement throughput. The device has loading platforms (11-1, 11-2) on which cryogenic probes (P1, P2) are loaded. Each loading platform has a horizontal drive mechanism, a vertical drive mechanism, and a spacing mechanism. The device further includes probe cooling devices (14-1, 14-2) for circulating a refrigerant to and from the cryogenic probes (P1, P2) via transfer tubes (12-1, 12-2) made of a flexible material, thus cooling the probes (P1, P2). A temperature-controlled gas feeder (18) supplies a temperature variable gas for temperature adjustment to the probes (P1, P2). A vacuum pumping system (15) evacuates the interiors of the probes (P1, P2) via vacuum pipes (17-1, 17-2) made of a flexible material.

The present invention provides, in a method for measuring a subject substance by using a binding partner that specifically recognizes a substance to be measured, a detection agent for amplifying a signal from a reporter substance that indirectly binds to the substance to be measured via the binding partner, and a signal amplification method using the detection agent. The present invention pertains to the detection agent in which the binding partner which specifically recognizes a substance to be measured is immobilized on gold nanoparticles together with a plurality of the reporter substances.

Embodiments of the invention disclose a medication reminding device based on a biological clock. The medication reminding device comprises an infrared radiation temperature detector, an electric signal detector, a sleep detection unit, an ear cavity adaptive shell, a wireless transmission circuit and an intelligent terminal, wherein the infrared radiation temperature detector, the electric signaldetector, the sleep detection unit, the wireless transmission circuit and the intelligent terminal are arranged in the ear cavity adaptive shell; the infrared radiation temperature detector is used for receiving infrared radiation signals from eardrums and the deep parts of a peripheral ear cavity; the electric signal detector collects temperature data signals output by the infrared radiation temperature detector at preset intervals and sends the temperature data signals to the intelligent terminal through the wireless transmission circuit; the sleep detection unit comprises a three-axis accelerometer, and is used for detecting the activity amount of the human body and the posture of the head every other preset time and sending the activity amount and the posture of the head to the intelligent terminal through the wireless transmission circuit; and the intelligent terminal has a wireless data receiving function and is used for receiving data from the electric signal detector and the sleep detection unit.

The invention relates to a method for measuring a geometrical shape of a stratified interface of a two-phase flow. The method is used for measuring the form of the stratified interface with conductivity difference. An adopted parallel line array sensor comprises two groups of parallel line electrodes, wherein one group of the parallel line electrodes are distributed on the cross section of the same pipeline on the upstream and are exciting electrodes, the other group of the parallel line electrodes are distributed the cross section of the same pipeline on the downstream and are receiving electrodes, the exciting electrodes and the receiving electrodes on the opposite positions form paired parallel line electrodes, and each electrode is fixed on a fixed component and penetrates through a horizontal measurement pipeline. The method comprises the following steps: determining the geometrical dimension of the parallel line array sensor on the premise that the form of an oil-water stratified interface is not damaged by the parallel line array sensor; sequentially measuring each line electrode pair, so as to collect a frame of measurement data; and calibrating measurement respond of the parallel line array sensor by virtue of the distribution of static stratified gas and water phases in the horizontal measurement pipeline.

The invention discloses a signal processing method of an acoustic emission tower crane safety detection system. The signal processing method of the acoustic emission tower crane safety detection system comprises the following steps: 1, denoising a signal through wavelet analysis; 2, selecting a wavelet, re-decomposing, and performing signal reconstruction to complete characteristic signal extraction; 3, performing severity pattern recognition on an acquired acoustic emission signal by using a BP neural network; 4, dividing the severity of the acoustic emission signal into a plurality of levelsaccording to an extracted characteristic signal for safety evaluation. By the signal processing method of the acoustic emission tower crane safety detection system, the acoustic emission tower cranesafety detection system can achieve early warning of early damage, can monitor expansion of the damage, has high sampling rate and high conversion rate, and can achieve high-precision and high-sensitivity measurement.

A compound represented by the formula (I) (R¹ represents hydrogen atom or a monovalent substituent; R² and R³ represent hydrogen atom, an alkyl group, or a halogen atom; R⁴ and R⁵ represent an alkyl group or an aryl group; R⁶ and R⁷ represent hydrogen atom, an alkyl group, or a halogen atom; R⁸ represent hydroxy group or a dialkoxyboranetriyl group; and X represents silicon atom, germanium atom, or tin atom), which is a novel fluorophore usable as a mother nucleus of an off/on type fluorescent probe not utilizing the intramolecular photoinduced electron transfer.

A method of measuring the length of a G tail sequence, characterized by hybridizing the G tail of an nondenatured chromosomal DNA in a sample with a labeled DNA probe having a sequence complementary to the telomere repeat sequence, measuring chemiluminescence from the hybridized DNA probe, and determining the length of the G tail sequence from the measured value, and a kit used for use in such a method.