78 results about "Biological clock" patented technology

The invention discloses a method, apparatus and program for evaluating life styles. Disclosed herein is a life-style evaluation method including the steps of acquiring information on a form of a living habit prescribing a life style, obtaining a virtual biological-clock rhythm curve by reflecting the information in a reference biological clock rhythm curve on a basis of the degree of an effect given by the form of the living habit on a biological-clock rhythm curve, and setting an indicator of the life style on a basis of the virtual biological-clock rhythm curve.

The present invention includes the disclosure of the hPER2 gene and a mutant of the hPER2 gene that participates in the human circadian biological clock. The product of the mutant hPER2 gene found in some familial advanced sleep phase syndrome patients is hypophosphorylated by casein kinase epsilon due to the serine-to-glycine mutation caused by the point mutation of the genomic sequence. Specifically, this serine-to-glycine mutation affects the casein kinase epsilon binding region of the hPER2 protein, thus blocking the phosphorylation cascade ordinarily caused by the binding of casein kinase epsilon to hPER2.

The invention discloses a human body period expression gene identification method based on an RNN-CNN neural network fusion algorithm. The method comprises the steps of performing missing filling andtime sequence period extension on original data, then establishing a high-quality learning dataset through a data level, performing thermal graph clustering on period expression data for preliminarilyunderstanding the specific expression of a biological clock gene in a visual sense angle, then combining a recurrent neural network algorithm and a convolutional neural network algorithm for obtaining an RNN-CNN fused algorithm by means of a deep learning algorithm, and performing periodical and non-periodical subtype classification on an RNN-CNN fused algorithm classifier and common deep learning algorithms CNN and RNN, performing cross validation on a classifying result, and performing evaluation by means of an accuracy score, a recall rate and a comprehensive evaluation index.

The invention relates to a high-quality ecological pig feeding method, which comprises the aspects in healthcare feed, regular feeding, ecological environment and healthy daily life. The healthcare feed is traditional Chinese medicine feed capable of promoting digestion, increasing immunity, improving feed conversion rate, improving daily weight increase and increasing pork quality, and can effectively substitute for antibiotics and hormones; and by providing cooked food, the digestion and the absorption of live pigs are facilitated, the body health of the live pigs is facilitated and the pork quality of the live pigs is improved. By letting the live pigs out of pigsties for exercise, the body health of the live pigs is improved and the possibility of antibiotic injection because of sickness is reduced. Regular feeding and healthy daily life are compliant with the rhythm of the biological clock of the live pigs, the health of the live pigs can be further improved and the pork quality is improved. By providing an ecological environment, excrements such as fetes, urine and the like can be rapidly decomposed, the pigsties are enabled to be free of pollution and smell and the living quality of the live pigs is improved.

The invention discloses an infant or pet nursing method. The method includes the steps that audio signals of infants or pets are acquired; the acquired audio signals are compared with prestored standard information; translation information of the audio signals of the infants or the pets is acquired. According to the voice of the infants or the pets, the acquired audio signals are compared with the standard information in a database, languages of the infants or the pets are translated, and meanwhile through user operation, the collected information is marked, data analysis is conducted through a system, and prompt information is provided before the biological clock of the infants.

The invention provides a sleep body motion recognition method. The method comprises the steps of using an acceleration sensor to collect three-dimensional acceleration data in a plurality of body movements during sleeping of a user and processing the data to establish a plurality of standard models at a normal speed; collecting a novel sleep action of the user, and generating a test template for the sleep action of the user; determining body motions during the sleeping of the user through a DTW algorithm; obtaining the physical activity frequency of the user through the body motion of the user; combining the physical activity frequency and a subjective standard of the user to analyze and assess the sleep state of the user. The smart wearable device based on the sleep body motion recognition method or the sleep quality assessment method helps the user to calculate sleep time and body activity rules in order to better understand own biological clock, and urges the user to develop bettersleep habits, understand and grasp the rhythm of turning or activity during sleep, pay attention to physical health, and improve own result of sleep.

A personal grounding device that is used to ground a human being and provides a human being a device to directly and naturally equalize one's body to the same energy level, or potential, as the Earth. This equalization results in synchronizing the person's internal biological clocks, hormonal cycles, and physiological rhythms and in supplying the body with healing and free, positively charged electrons (called free radicals). These are abundantly present on the surface of the Earth. Electrically speaking free radicals have a positive charge. The grounding directly equalizes the body of the person to the same energy level, or potential (zero), as the Earth. The device is comprised of a closed grid (like a heating pad) in an encasement to form a mat; a lead to the grid from a ground; a ground lead (natural or artificial); and a means for connecting the field grid to the ground.

The invention relates to an ergonomic air conditioner and a temperature adjustment method. Through the external temperature detection unit, the main unit of the air conditioner can continuously pay attention to and detect the change and rhythm of the real ambient temperature in the external nature. According to different application occasions, the present invention includes two control modes: temperature difference stabilization mode and biological clock mode. In rooms where people come and go frequently, such as shops, buses, etc., the temperature difference stabilization mode is adopted, and the temperature difference between indoor and outdoor is stable, and there will be no sudden cold or hot; With the biological clock mode, the temperature changes according to the natural rhythm, and the biological clock of the human body will not be disturbed.

The invention discloses an environmental light self-adaptive adjusting method used for biological clock adjusting glasses. The environmental light self-adaptive adjusting method includes the following steps: step 1, presetting an adjusting light intensity value a; step 2, monitoring and collecting an environmental light intensity value B; step 3, calculating intensity D of light which is already used in environmental light according to a formula: D=cXB, wherein c is a constant and is determined by wave length of a used light source; step 4, calculating to acquire an intensity value of light that the light source needs to provide according to a formula: E=A-D; step 5, if a value of the E is smaller than 0, closing an LED array, and if the value of the E is larger than 0, using a method of adjusting duty ratio to adjust a light intensity value of the LED array to be E according to the value of the E. The environmental light self-adaptive adjusting method is practical and more intelligent in adjusting LED lamp intensity, a light source emitted by an LED is combined with natural light to enable an intensity value of light received by a user to be constant all the time, intensity of light needed by the user can be adjusted accurately and quickly, and the user can feel more comfortable during use, so that the biological clock of a human body can be adjusted better.

The invention relates to a medicinal composition of an agomelatine-containing enteric capsule. The medicinal composition is characterized in that the composition is mainly composed of a medicine-containing part and an enteric material part. 1mg-100mg of the active component agomelatine is contained. The enteric preparation provided in the invention is used for treating depression and anxiety, adjusting sleep rhythm and regulating biological clock, and has the advantages of small main drug content and high bioavailability.

The invention relates to a medicinal composition of agomelatine-containing enteric-coated tablets. The medicinal composition is mainly composed of a medicine-containing tablet portion and an enteric coating portion, wherein the content of an active component-agomelatine is 1 mg-50 mg. The enteric-coated tablets provided by the invention can be used for treating depression and anxiety, have the functions of adjusting sleeping rhythms and biological clocks, and have the advantages of low content of the main medicine and high bioavailability.

A composition having a normalizing action for infradian rhythm and/or a synchronization promoting action for circadian rhythm (biological clock) containing arachidonic acid and/or an arachidonic acid-containing compound.

An on-line biological water quality monitoring model based on biological rhythms of golden crucian carps and a building method thereof are disclosed. The method includes (1) selecting organisms to be tested; (2) preparing a trace pollutant solution, and determining the concentration of a medicine for tests according to surface water environment quality standards of the People's Republic of China; (3) arranging a blank group and an experimental group, with each group comprising at least three parallel groups, putting the organisms to be tested in the blank group and the experimental group into different sensors of an organism on-line behavior detector, adding aerated water into the sensors of the blank group, adding the prepared trace pollutant solution into the sensors of the experimental group, adding at least two golden crucian carps into each sensor after the aquatic organism on-line behavior detector is calibrated, performing a water flowing test, and allowing a system to automatically collect and record data; (4) performing data processing and result analyzing; and (5) building a biological clock model.

An apparatus for adjusting the biological clock of a traveler is constructed to has a body, which can be made in the form of an article of clothing for wear by a user or a footstool for resting the user's legs, and a light source installed in the body and used to emit light of a wavelength within about 400 nm-700 nm to irradiate a part of the body of the traveler having many blood vessels relatively close to the surface, a location at which light interacts with photoactive substances in the blood.

The invention relates to a method and an illuminometer of measuring illuminance of human body biological clock effect. The method and the illuminometer of measuring illuminance of the human body biological clock effect are characterized by utilizing the visual effect relevant with working and sleeping of a human body. The method and the illuminometer of measuring the illuminance of the human body biological clock effect comprise a photometry probe (1), a photoelectricity amplifying module (2), a data processing module (3), a data locking module (4) and a number-reading displayer (5). The photometry probe (1) is composed of a cosine reviser (11), a corrector (12) matched with a visual spectral response curve of the human body biological clock effect and a silicon photocell, and therefore the measuring result is enabled to be identical to the vision sensitization of the human body biological clock effect.

The invention discloses a biological clock nerve-soothing hypnosis medicinal pillow. Chinese medicinal herbs and plant leaves are filled in the medicinal pillow. The medicinal pillow comprises the following components in part by weight: 10 to 20 parts of peanut leaf, 10 to 20 parts of sunflower disc, 10 to 20 parts of sunflower leaf, 10 to 20 parts of tuber fleeceflower stem, 10 to 20 parts of seed of wild jujube, 10 to 20 parts of valerian root and 10 to 20 parts of juncus effusus. The medicaments are compatible, coordinate yin and yang, have synergetic effect and definite curative effect, and can be widely applied to various asomnia symptoms. The medicinal pillow is convenient to use, and can be used for treatment in bed rest; and the medicinal pillow is a result researched by combining Chinese medicinal theory and biological clock effects of Chinese medicaments and plants based on years of clinical research and application, and is obtained from an effective medicinal pillow formula determined by repeated proof, screening and clinical practice. After long-term use, the medicinal pillow can fully exert the biological clock effect of the Chinese medicaments in the medicinal pillow, and achieves the effects of strengthening brain, soothing nerve, calming, accelerating sleeping and prolonging life. The medicinal pillow is widely applied to asomnia and sleep disorders caused by various reasons.

A method for increasing the expressions of CLOCK, ARNTL and/or PER2 genes is provided, wherein the method comprises administering to a subject in need an effective amount of Momordica charantia extract. The method is useful for treating or preventing diseases related to CLOCK, ARNTL and/or PER2 genes, or regulating physiological functions related to CLOCK, ARNTL and/or PER2 genes. The method is especially for adjusting the biological clock, improving sleep quality, and facilitating sleep.

The invention relates to a construction method and application of a drosophila model for simulating human diseases, in particular to a construction method and application of a drosophila model for axonal Charcot-Marie-Tooth (CMT2). The model constructs the amino acid mutation of the endogenous corresponding human ATP1A1 gene of the Drosophila by a genome editing method, and evaluates the pathological phenotype by utilizing the changes of brain nervous system loop, biological clock related behavior, life span and exercise ability. The model and the pathological evaluation means established by the invention have the advantages of simple operation and strong repeatability, and the obtained CMT2 drosophila model can be used for researching the pathological process and mechanism of the disease,can also be used for screening and verifying medicines for delaying or treating the CMT2 disease on a large scale, and has a good application prospect.

The invention discloses a novel method for adjusting the time difference reaction of the mammal, relating to a novel protein Magedl for adjusting the circadian rhythm and the mammal, wherein the novel protein Magedl plays an important part in maintaining the normal biological clock function. In a mouse with the Magedl, the core biological clock molecular amplitude of the mouse is changed to be small, the day-night cycle of the mouse is changed to be short, and the adjusting speed in the simulative time difference reaction is accelerated. Therefore, the Magedl can be taken as a drug target for curing the time difference reaction of human body.

The present invention provides a soy GmLCL1 protein, which is: 1) a protein comprising an amino acid sequence represented by SEQ ID NO.1; or 2) a protein, wherein an amino acid sequence represented by SEQ ID NO.1 is processed by substituting, deleting, or adding one or a plurality of amino acids to form the amino acid sequence of the protein, and the protein is derived from the protein 1) and has the same activity as the protein 1). The present invention further provides a gene GmLCL1 encoding the protein. With over-expression of the gene, plant flowering can be significantly inhibited, and a growing period can be prolonged. The gene and the encoding protein can be used for solutions of problems of asynchronous flowering period in cross breeding, and growing period controls, photoperiod sensitivity and introduction of various crops, vegetables, fruits and flowers.

The invention discloses a culture method for ecological wild boars. The method comprises following steps: (1) health-care fodder; (2) ecological environment; (3) healthy living. The culture method for ecological wild boars has following beneficial effects: based on eating habits and nutrition demands, fodders can be arranged so that good palatability, high protein content, full amino acid and rich vitamin content are obtained; immunity and disease prevention of wild boars are obtained; in addition, though weight-gaining speed of wild boars may slow down due to indoor ventilation, physical health of wild boars is enhanced so that possibilities of injecting antibiotics due to diseases is reduced; regular feeding and healthy living are compatible with rhythm of biological clocks of wild boars; health degree of wild boars is improved so that quality is improved; an ecological environment can rapidly digest and decompose excreta such as manure such that hog houses are pollution-free and odor-free so that living quality of wild boars is improved.

The invention discloses a bionic illumination lamp. The lamp comprises a frame assembly, an LED light source module, a diffusion plate, a light guide plate, a rear cover plate, a junction box and a control device, wherein the frame assembly forms a frame, the LED light source module is arranged on the inner side wall of the frame assembly, and a plurality of LED lamps are arranged on the LED lightsource module; an inner frame of the frame assembly is filled with the diffusion plate, and the light guide plate is arranged on the diffusion plate; the rear cover plate located on the light guide plate is fixed to the frame assembly, the junction box is fixed to the rear cover plate, and a driving power supply and an aviation plug are arranged on the junction box. The control device is connected with the aviation plug, and the control device is configured to control the color temperature change of the LED lamps according to time change. According to the lamp, natural light can be simulatedconveniently, so that the biological clock disorder is avoided.