5 results about "Biological clock" patented technology

Provided herein are methods and compositions for an epigenetic clock comprising differentiation-independent methylation sites to asses biological age of a human subject.

This invention provides an artificial lighting system and method for promoting circadian health. [Solution] Methods, systems, and computer-readable media utilizing artificial lighting regulate the human circadian clock. By utilizing light-emitting diodes (LEDs) that emit wavelengths associated with the human opsin absorption spectrum, the device can stimulate human opsins. For example, the device replicates normal sunlight (for example, based on the season or time of day) by emitting light that changes in rhythmic intensity or spectral modulation.

The present invention relates to biological clocks for measuring skin aging based on the protein expression level measured in a sample of a person's stratum corneum.

The present invention provides agents and other devices that can advance the phase of the circadian rhythm. [Solution] The body clock regulator contains bergamot oil, geranium oil, and cedarwood. It contains at least one of Virginia oil, citral, and β-caryophyllene. It contains an active ingredient that advances the phase of the expression rhythm of clock genes.

The present invention provides a method for generating a biological clock containing a DNA methylation map applicable to at least two different sample types, the method comprising: (i) providing a first set of DNA methylation maps generated from at least two different sample types from multiple subjects; (ii) generating a composite DNA methylation map from the first set of DNA methylation maps, wherein the composite DNA methylation map contains methylation sites having a matching state in the different sample types; and (iii) generating a biological clock using the composite DNA methylation map with a reference DNA methylation map from one of the at least two sample types.