The invention discloses an intelligent manufacturing MES system which comprises a basic modeling module, a plan scheduling module, a comprehensive production module, a logistics management module, a quality management module, an energy management module, an equipment management module, a central control center management module and an abnormal Andon module. The basic modeling module is used for completing establishment of factory layout, establishment of product information and establishment of external resources. The plan scheduling module is used for establishing a production order, carryingout material preparation and distribution for a warehouse, work order scheduling, production execution, inspection, packaging and production warehousing. The comprehensive production module is used for managing a generated full-service process. The logistics management module is used for managing a production material taking management process and a production warehouse-in management process; andthe quality management module is used for carrying out inspection object maintenance on a purchasing department, a workshop department and a sales department. The invention provides a perfect intelligent manufacturing MES system, thereby realizing intelligent manufacturing full-process monitoring.