This invention provides a tear collection patch, comprising, from near to far from the eye, a biomimetic flexible substrate, a superhydrophilic drainage layer, a storage cavity, and a sealing cap. The superhydrophilic drainage layer includes a hydrophilic medical
fiber membrane and a superhydrophilic
coating. The hydrophilic medical
fiber membrane is prepared by
electrospinning medical hydrophilic fibers, and the superhydrophilic
coating is formed by immersing the hydrophilic medical
fiber membrane in a superhydrophilic
coating solution and then curing it. The biomimetic flexible substrate has a biomimetic
adhesive layer that automatically adheres to the target location. The superhydrophilic drainage layer absorbs
tears into the storage cavity. This invention achieves instantaneous tear absorption and painless adhesion by designing a drainage layer with superhydrophilic properties and a biomimetic
adhesive substrate working synergistically. The biomimetic
adhesive substrate reduces the risk of corneal
irritation, ensuring that the collected
tears are in a normal physiological state rather than due to stress
secretion, thus solving the problems of reliance on manual operation and low efficiency in traditional
collection methods.