206results about How to "Improve progress" patented technology

The present invention concerns a method and apparatus for automatic processing a biological sample on a carrier, perhaps robotically, by applying predetermined amounts of reagents in a predetermined sequence according to a processing protocol, the processing including pre-treatment steps, under the control of an adaptive processing control system using a sample process parameter input that may be independent and an independent process parameter memory that does not interrupt process operation when being used, such that samples may be added or removed without interrupting the processing of other samples. Also included is an image capture function for sample and reagent identification and process monitoring, as well as temperature regulation and environmental control functions.

The present invention concerns a method and apparatus for automatic staining or other processing of a biological sample on a slide, perhaps robotically, by applying predetermined amounts of reagents in a predetermined sequence according to a processing protocol, the processing including pre-treatment steps, under the control of an adaptive processing control system. Further provided is a method of antigen retrieval, the method comprising contacting, within a heated processing tank of an automated staining apparatus, at least one biological sample with at least one composition for antigen retrieval comprising at least one chelating agent, at least one detergent and at least 50% by volume of at least one liquid that facilitates antigen retrieval.

The invention discloses a method for carrying out engineering progress supervision by use of three-dimensional panoramic technology by combining BIM technology. The method comprise following steps of S1: constructing a BIM model for an engineering project; S2: carrying out three-dimensional data acquisition on a construction field of the engineering project and making a three-dimensional panoramic image of the engineering field; S3: associating and integrating the BIM model in the S1 and the three-dimensional panoramic image of the engineering field in the S2: and S4: carrying out synchronous comparison according to positions and carrying out switching comparison according to different time schedules on the associated and integrated data of the three-dimensional panoramic image and the BIM model. According to the invention, sense organ recognition between actual construction conditions and designing models is effectively improved; effective reference basis is provided for construction schedule conditions and onsite construction conditions; and schedule management and quality management of the whole designing and construction stage are effectively improved.

The present invention concerns a method and apparatus for automatic processing a biological sample on a carrier, perhaps robotically, by applying predetermined amounts of reagents in a predetermined sequence according to a processing protocol, the processing including pre-treatment steps, under the control of an adaptive processing control system using a sample process parameter input that may be independent and an independent process parameter memory that does not interrupt process operation when being used, such that samples may be added or removed without interrupting the processing of other samples. Also included is an image capture function for sample and reagent identification and process monitoring, as well as temperature regulation and environmental control functions.

This document provides methods and materials related to treating skin cancer. For example, methods and materials relating to the use of a taxane compound, an alkylating agent, and an anti-VEGF polypeptide antibody to treat skin cancer are provided.

The present invention concerns a method and apparatus for automatic staining or other processing of a biological sample on a slide, perhaps robotically, by applying predetermined amounts of reagents in a predetermined sequence according to a processing protocol, the processing including pre-treatment steps, under the control of an adaptive processing control system. Further provided is a method of antigen retrieval, the method comprising contacting, within a heated processing tank of an automated staining apparatus, at least one biological sample with at least one composition for antigen retrieval comprising at least one chelating agent, at least one detergent and at least 50% by volume of at least one liquid that facilitates antigen retrieval.

A segment-assembled type pier column member with a steel-concrete composite structure includes a reinforcement tube embedded in a pile cap, wherein the reinforcement tube is connected with a bottom of a lower segment of a hollow steel tube pier and is poured with concrete, and pier columns in upper and lower segments are reinforced by means of segment connecting and being embedded with local reinforcing meshes. A steel cross beam is connected with an upper segment of the hollow steel tube pier in an assembled way. A pre-stressed tensioning duct is reserved between the steel cross beam and the pier column in the upper segment.

Disclosed herein are methods of preventing or delaying the recurrence of melanoma in a subject with bis(thio-hydrazide amides) represented by a formula selected from Structural Formulas (I)-(IX) or pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising these bis(thio-hydrazide amides) and compositions comprising these bis(thiohydrazide)amides and one or more anti-cancer agent.

Polysaccharide preparations lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided.

A method of administering a suspension of paclitaxel particles into the peritoneum is provided. A corresponding method of treating a disease, disorder or condition that is therapeutically responsive to paclitaxel is also provided. The methods provide improvements over comparator formulations containing an equivalent dose of paclitaxel.

An exoskeleton (100) system comprises at least one garment selected from the group consisting of a shirt or vest (110), short or pants (120), an upper arm sleeve (130), a lower arm sleeve (140), a thigh sleeve (150), and a leg sleeve (160) wherein the garment is a multilayer construct that essentially comprises an inner layer (201) of nylon material, a middle layer (202) made of neoprene, an outer layer (203) made of plush material; and an article (300) with attached hook and loop fasteners (301) to be mounted onto the garment by securing the hook and loop fasteners (301) onto any spots of the outer layer (203).

The invention provides a method of preventing, delaying, or reversing the progression of Alzheimer's disease by administering an Aβ42 lowering agent to a mammal under conditions in which levels of Aβ42 are selectively reduced, levels of Aβ38 are increased, and levels of Aβ40 are unchanged. The invention provides methods and materials for developing and identifying Aβ42 lowering agents. In addition, the invention provides methods for identifying agents that increase the risk of developing, or hasten progression of, Alzheimer's disease. The invention also provides compositions of Aβ42 lowering agents and antioxidants, Aβ42 lowering agents and non-selective secretase inhibitors, as well as Aβ42 lowering agents and acetylcholinesterase inhibitors. The invention also provides kits containing Aβ42 lowering agents, antioxidants, non-selective secretase inhibitors, and / or acetylcholinesterase inhibitors as well as instructions related to dose regimens for Aβ42 lowering agents, antioxidants, non-selective secretase inhibitors, and acetylcholinesterase inhibitors.

Provided are assay systems for determining the therapeutic or toxic effect of a putative drug based on assaying its activity in cells which have been differentiated in vitro from stem cells, and induced to display a phenotype that resembles a disease to be treated.

A method induces bacteria to enter into viable, but nonculturable state. The method includes subjecting a target bacterium to high pressure carbon dioxide treatment so as to make it enter into the viable, but nonculturable state, which can be demonstrated experimentally. The viable but nonculturable state can be entered quickly, such as within one hour.

An apparatus and method for making expandable honeycomb structures suitable for use as window coverings is provided. Material is fed to a folder and past a cutter. Adhesive is applied to the material downstream of the cutter and the material is cut to desired lengths. The cut strips of material are stacked with similarly formed strips to form the honeycomb structure.

The invention provides an AGV charging management method. The method includes the following steps that a charging threshold value a, a target electric quantity value b and a lowest electric quantity threshold value c are set; a total real-time electric quantity value e of AGVs in a transport system is monitored; an expected number g of to-be-charged AGVs in the transport system is calculated; theg AGVs are selected as the to-be-charged AGVs, whether the AGVs marked with execution of charging tasks exist in the expected number g of the to-be-charged AGVs or not is judged, according to the charging threshold value a and the lowest electric quantity threshold value c, the precedence levels of the to-be-charged AGVs are judged, and the to-be-charged AGVs are sequentially moved to operating charging piles to be charged according to the precedence levels; and an operation in a new round is started after one to-be-charged AGV is charged. The provided transport system applies the above AGV charging management method. By the adoption of the AGV charging management method, the charging precedence levels of the AGVs can be arranged quickly; and the transport system can assess the total electric quantity of the AGVs in the transport system and then execute charging management, so that AGV charging management decision making time is shortened.

Polysaccharide preparations lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided.

The invention provides a method of preventing, delaying, or reversing the progression of Alzheimer's disease by administering an Aβ42 lowering agent to a mammal under conditions in which levels of Aβ42 are selectively reduced, levels of Aβ38 are increased, and levels of Aβ40 are unchanged. The invention provides methods and materials for developing and identifying Aβ42 lowering agents. In addition, the invention provides methods for identifying agents that increase the risk of developing, or hasten progression of, Alzheimer's disease. The invention also provides compositions of Aβ42 lowering agents and antioxidants, Aβ42 lowering agents and non-selective secretase inhibitors, as well as Aβ42 lowering agents and acetylcholinesterase inhibitors. The invention also provides kits containing Aβ42 lowering agents, antioxidants, non-selective secretase inhibitors, and / or acetylcholinesterase inhibitors as well as instructions related to dose regimens for Aβ42 lowering agents, antioxidants, non-selective secretase inhibitors, and acetylcholinesterase inhibitors.

The invention discloses a comprehensive and integrative gas drainage method which can be used for solving the problems that gas drainage is difficult to realize due to soft coal beds and low air permeability of the existing mines and the drainage effect of the current single gas drainage technology is unsatisfied. The method disclosed by the invention comprises the following steps: (1) high-position fracture borehole drainage of the top plate of a coal bed; (2) heterotropic high-position borehole drainage of a return airway; and (3) upper corner pipe-laying drainage of a gob. According to the invention, the stress field and fracture field caused by mining and a gas migration rule are fully utilized, so that drilled holes are high in drainage efficiency and flexible in arrangement, a drainage system is simple, the gas concentration at a drainage outlet can be up to 15-24%, and the gas drainage efficiency can reach 55-67.3%. The method disclosed by the invention is a new technology and method in fully mechanized caving face gas control methods, can be used for reducing the occurrence of excessive gas accidents and reducing the losses of life and property, has very important and far-reaching significance and is strongly worthy to be popularized and applied.

The invention relates to a control method and a full-servo control system for operating a multi-axis mechanical arm. The control method comprises the steps of setting function instruction data by the program editing window of an input / output interface or a function conversion module which is controlled by a key and transmitting the data to a plurality of groups of any memory storage modules for storage; calling the data, transmitting the data to a signal processing module after the processing by a data operation module and a data coding module and conversing the data into a function signal, later amplifying the data according to the recognizable format of a main control subsystem; calling a function execution signal and corresponding die number within a set period by a set servo module and an electric control execution mechanism to finish the control operation of the mechanical arm; arranging a multi-axis control module and providing a fixed mode to select to implement different functions; and automatically detecting the fault and memorizing the fault number by a fault detection module, implementing automatic alarming function by micro adjusting the axis position when in operation and automatically accumulating and calculating the operation times, and jumping out of an infinite circular operation state.

To avoid accelerated progression of deterioration of a semiconductor laser, an LED, and the like to extend their lives while adjusting a balance of a plurality of colors, such as R, G, and B, by feedback control, a deterioration controllable monochromatic light source module is configured to: calculate a substantial upper limit Iu, determine an operation coefficient hx based on a deterioration coefficient dx, perform feedback control of the output current Ix of each drive circuit, and output a light intensity detection signal to the outside. An integrating control circuit calculates a monochromatic light intensity sum σ by a sum of light intensity detection signals from the monochromatic light source modules belonging to the same wavelength band and determines a light intensity target signal so that a ratio of the monochromatic light intensity sum σ to the monochromatic light source modules in different wavelength bands is a predetermined ratio.

The present invention is directed to a method for treating tumors and cancer cells by administering an immunocytokine following radiation treatment. This combination of treatments can stimulate an immune response at irradiated and non-irradiated sites, which is useful in eradicating cancer cells that have spread from the site of the primary tumor. In addition, immunocytokines can be administered at a dose that is less that the maximum tolerated dose, which reduces the side effects associated with immunocytokine therapy.

The present invention relates to the identification of p53 biomarker profiles that predict response in patients with hyperproliferative disease such as cancer to a therapy, and their use in methods of treating such patients with an anti-hyperproliferative disease gene therapy.

The invention relates to an ADAS and V2V combined beyond visual range sensing and publishing method and system. The sensing and publishing method comprises data integration publishing process and integrated data receiving handling process; the data integration publishing process utilizes environment sensing data published and integrated by a V2V module, the integrated data receiving handling process utilizes the integrated data and performs collision warning or risk prompt by using a scene classification handling algorithm. By performing state inverse, data filtering and data integration on the collected data of the traditional ADAS vehicle with the V2V module, the sensing and application range of the equipped V2V module vehicle is improved, the application and promotion progress of the V2V module is greatly promoted from the technical angle. The sensing range of the vehicle and the reliability of the V2V application can be improved, and the dependency on an installation rate by the V2V application is reduced.

The invention discloses a method for testing a satellite navigation receiver. The method comprises the following steps of: resolving effective information from test data files acquired by the receiver; storing the effective information into a database; setting a judgment rule; indexing records according with the judgment rule from the database; and positioning the indexed records to the test data files. By utilizing the technical scheme, the development efficiency is improved, the cost is saved, and the progress is improved.

An exoskeleton (100) system comprises at least one garment selected from the group consisting of a shirt or vest (110), short or pants (120), an upper arm sleeve (130), a lower arm sleeve (140), a thigh sleeve (150), and a leg sleeve (160) wherein the garment may be a multilayer construct that comprises an inner layer (201) of nylon material, a middle layer (202) made of neoprene, an outer layer (203) made of plush material; and an article (300) with attached hook and loop fasteners (301) to be mounted onto the garment by securing the hook and loop fasteners (301) onto any spots or locations of the outer layer (203).

The present disclosure relates to: a) a crystalline composition of essentially pure Form IV of N—((R)-2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide; b) pharmaceutical compositions comprising the crystalline composition of essentially pure Form IV of N—((R)-2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide, and, optionally, a pharmaceutically acceptable carrier; and c) methods of treating a tumor, a cancer, or a Rasopathy disorder by administering the crystalline composition of essentially pure Form IV of N—((R)-2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide to a subject in need thereof.