The invention discloses bridge coarse aggregate active powder concrete and a preparation method thereof. The coarse aggregate active powder concrete comprises, by weight, 100 parts of cement, 20-60 parts of blending materials, 2-10 parts of interface modifying agents, 60-120 parts of fine aggregates, 40-120 parts of coarse aggregates, 10-60 parts of fibers and 15-30 parts of water. Under conventional curing processes such as natural conditions, the coarse aggregate active powder concrete has super-high compressive strength, bending tensile strength and tensile strength and bonding strength andlow contraction performance and further has high elasticity modulus, anti-fatigue performance and durable performance and excellent construction performance, dead weight and shrinkage and creep influence of a bridge can be reduced, and the span, the structural stiffness and the bearing capacity of the bridge can be remarkably improved, and the service life of the bridge is prolonged.